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Psycho-emotional stress and congential ophthalmopathology of children in zone of spitak earthquake
PSYCHONEUROLOGICAL
WHO
PERSONS
DISTURBANCES
ENDURED
INDIVIDUAL AND GENETICALLY DETERMINED BEHAVIOURAL EFFECTS OF TUFTSIN AND ITS ANALOGUE IN STRESS SITUATIONS. I. I. Kozlovskii, T. P. Semenova, N. I. Medvinskaya, R. Czabak-Garbacz Institute of Pharmacology Rus. Med. AC. Sci., Institute of ceil Biop&ics Rw. AC. Sci.. Russia rmd Deparmaent of Human Physiology, University Medical School, Lublin, Poland
IN
PSYCHOEMOTIO-
NAL STRESS IN THE ZONE OF EARTHQUAKE IN ARMENIA Khachatrian S.H., Hovhanessian M.G. Department
Planning,
of
Pathophysiology,
Department
Center
of
Reproduction,
of
Farnib Medical
The anxiolytic effects of the tuftam and its analogue, on the adaptive behavioural reactions under stress of the different genesis have been studied. The Wistar rats with different resistance to stress (with passive and active type of emotionfear reaction) and inbred mice we used in acute and chronic experiments. The peculiarities of the individual and genetically determined animal emotional reactions in extreme situations have been investigated. It has been shown that the synthetic analogue of tuftsin (heptapeptide, including tripeptide Pro-GlyPro in its structure) demonstrates a selective anxiolytic activity. Under both the unavoidable and avoidable stress conditions the heptapeptide (0,3mg/kg) shows the anxiolytic activity in the rats unresistant to stress (p
University of Erevan, RA The total index of the health of all population of catastrophe,
which somehow
in the zone
suffered from the Spitak
earthquake,
deteriorated
catastrophe
in 15-2 times. 200 men have been observed
from the zone EEG), (hormonal,
during the last 10 years after the
of earthquake.
neurological,
Biophysiological
neuropsychiatric,
immunological)
methods
(ECG,
radioimmune
have been used, as
well as doplerographic
investigations
of vessels of genital
organs.
neurasthenic
syndrome
In 93 men
component them:
of fear neurosis has been diagnosed,
depression.
psychoemotional
It’s
shown
that
negative
with action
stress affects not only the course
gravity of the disease, but also the development symptomocomplexes:
somatovegetative
the
in 32 of of and
of new
disturbances,
as
well as infertility.
EMOTIONAL AND PHYSICAL STABITILITY OF RATS IN ECOLOGICAL STRESS AND IT’S DEPENDENCE UPON ENVIRONMENTAL CONDITIONS IN STAGE OF DEVELOPMENT M.A.Mirzojeva,T.N.Sonnov,S.I.Utkin,L.V Slotma I A.Kulitchenco,N.V Dotsenko,M J Voronma. Russian Stare Medical lJnllprsirq.Mosco~l: Russia We tried to make clear th: dependence of emotional and physical stability to the ecological stress adult rats upon the conditions they were grown up. One group of rats grew up in check cages as usual The other group were placed under additional emotional and physical activity (compulsory swimming). There were 3 tyles of modelled high water stress used upon the rats in their middle age. The behavioral reachions of the rats were checked and filmed, intervalograms were registered before the stress experiments and after them Rats kept in traming when growing up showed more physical endurance than rats grown up in usual conditionsbut they alsodemonstrated behavioral disturbance(deceleration of action by change of the mod.: of action lessening of searching activity) The emotional stability became smaller (the fear reac-tions were strengthened) and arrhythmias were larger. The reactions depended on the dimensions of the stress experiments. The method of training used in our experi-ments in order to strenghten the stability of growing rats to the noxious conditions of the environment turned out to be somewhat excessive and some disturbances in sphere of emotional behaviour and vegetative reactions were found in these rats when they were in their middle age alongside of the increased physical enduranct
PSYCHO-EMOTIONAL STRESS AND CONGENTIAL OPHTHALMOPATHOLOGY OF CHILDREN IN ZONE OF SPITAK EARTHQUAKE Kbachatrian
S.H., Malayan
AS.,
Yeghiazaryan
H.V.,
Dept of Pathophysiology, department of Ophthalmology, Medical University of Yerevan, Republican Ophthalmological Center of Armenia 039. Emotional Stress The present investigation aims at studying childrens’ congental stress conditions for people affected by disasters.
Our observations indicated that expressiveness and stability of psycho-emotional disorders after disasters were directly connected with character and massively of personally significant psycho-traumatic factor tragic consequences of disastrous earthquake. Patients with expressed congenital ophtbalmopathology were more frequently observed among mothers who have lost their family members, shelter and property (41,2%), and it proves again the special heaviness of the psycho-emotional stress endured.
223
WHO
PERSONS
DISTURBANCES
ENDURED
INDIVIDUAL AND GENETICALLY DETERMINED BEHAVIOURAL EFFECTS OF TUFTSIN AND ITS ANALOGUE IN STRESS SITUATIONS. I. I. Kozlovskii, T. P. Semenova, N. I. Medvinskaya, R. Czabak-Garbacz Institute of Pharmacology Rus. Med. AC. Sci., Institute of ceil Biop&ics Rw. AC. Sci.. Russia rmd Deparmaent of Human Physiology, University Medical School, Lublin, Poland
IN
PSYCHOEMOTIO-
NAL STRESS IN THE ZONE OF EARTHQUAKE IN ARMENIA Khachatrian S.H., Hovhanessian M.G. Department
Planning,
of
Pathophysiology,
Department
Center
of
Reproduction,
of
Farnib Medical
The anxiolytic effects of the tuftam and its analogue, on the adaptive behavioural reactions under stress of the different genesis have been studied. The Wistar rats with different resistance to stress (with passive and active type of emotionfear reaction) and inbred mice we used in acute and chronic experiments. The peculiarities of the individual and genetically determined animal emotional reactions in extreme situations have been investigated. It has been shown that the synthetic analogue of tuftsin (heptapeptide, including tripeptide Pro-GlyPro in its structure) demonstrates a selective anxiolytic activity. Under both the unavoidable and avoidable stress conditions the heptapeptide (0,3mg/kg) shows the anxiolytic activity in the rats unresistant to stress (p
University of Erevan, RA The total index of the health of all population of catastrophe,
which somehow
in the zone
suffered from the Spitak
earthquake,
deteriorated
catastrophe
in 15-2 times. 200 men have been observed
from the zone EEG), (hormonal,
during the last 10 years after the
of earthquake.
neurological,
Biophysiological
neuropsychiatric,
immunological)
methods
(ECG,
radioimmune
have been used, as
well as doplerographic
investigations
of vessels of genital
organs.
neurasthenic
syndrome
In 93 men
component them:
of fear neurosis has been diagnosed,
depression.
psychoemotional
It’s
shown
that
negative
with action
stress affects not only the course
gravity of the disease, but also the development symptomocomplexes:
somatovegetative
the
in 32 of of and
of new
disturbances,
as
well as infertility.
EMOTIONAL AND PHYSICAL STABITILITY OF RATS IN ECOLOGICAL STRESS AND IT’S DEPENDENCE UPON ENVIRONMENTAL CONDITIONS IN STAGE OF DEVELOPMENT M.A.Mirzojeva,T.N.Sonnov,S.I.Utkin,L.V Slotma I A.Kulitchenco,N.V Dotsenko,M J Voronma. Russian Stare Medical lJnllprsirq.Mosco~l: Russia We tried to make clear th: dependence of emotional and physical stability to the ecological stress adult rats upon the conditions they were grown up. One group of rats grew up in check cages as usual The other group were placed under additional emotional and physical activity (compulsory swimming). There were 3 tyles of modelled high water stress used upon the rats in their middle age. The behavioral reachions of the rats were checked and filmed, intervalograms were registered before the stress experiments and after them Rats kept in traming when growing up showed more physical endurance than rats grown up in usual conditionsbut they alsodemonstrated behavioral disturbance(deceleration of action by change of the mod.: of action lessening of searching activity) The emotional stability became smaller (the fear reac-tions were strengthened) and arrhythmias were larger. The reactions depended on the dimensions of the stress experiments. The method of training used in our experi-ments in order to strenghten the stability of growing rats to the noxious conditions of the environment turned out to be somewhat excessive and some disturbances in sphere of emotional behaviour and vegetative reactions were found in these rats when they were in their middle age alongside of the increased physical enduranct
PSYCHO-EMOTIONAL STRESS AND CONGENTIAL OPHTHALMOPATHOLOGY OF CHILDREN IN ZONE OF SPITAK EARTHQUAKE Kbachatrian
S.H., Malayan
AS.,
Yeghiazaryan
H.V.,
Dept of Pathophysiology, department of Ophthalmology, Medical University of Yerevan, Republican Ophthalmological Center of Armenia 039. Emotional Stress The present investigation aims at studying childrens’ congental stress conditions for people affected by disasters.
Our observations indicated that expressiveness and stability of psycho-emotional disorders after disasters were directly connected with character and massively of personally significant psycho-traumatic factor tragic consequences of disastrous earthquake. Patients with expressed congenital ophtbalmopathology were more frequently observed among mothers who have lost their family members, shelter and property (41,2%), and it proves again the special heaviness of the psycho-emotional stress endured.
223