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PT01.4: Energy and Macronutrient Intake at Age 70 is not Associated with Prevalence of Sarcopenia at Age 88
S30 Conclusion: The MNA-SF classification and Score, and the CC were shown to be an efficient nutritional indicator capable of identifying the 30-day mortality risk in this population. Disclosure of Interest: None declared.
PT01.3 A REVIEW OF NUTRITIONAL SCREENING TOOLS USED IN OLDER ADULTS L. C. Power1,2 *, D. Mullally1,2, M. A. de van der Schueren3,4, E. R. Gibney2,5, M. Clarke2,5, L. A. Bardon2,5, C. Corish1,2, on behalf of the MaNuEL Consortium. 1School of Public Health, Physiotherapy and Sports Science, 2Institute of Food and Health, University College Dublin, Dublin, Ireland, 3 Department of Nutrition and Dietetics, VU University Medical Centre, Amsterdam, 4Department of Nutrition and Health, HAN University of Applied Sciences, Nijmegen, Netherlands, 5 Department of Agriculture and Food Science, University College Dublin, Dublin, Ireland Rationale: Many nutritional screening tools (NSTs) are used in older adults (>65 years), each containing a diverse range of parameters and validated against different standards. An objective of the EU Malnutrition in the Elderly Knowledge hub (MaNuEL) project is to review existing NSTs used in older adults in various healthcare settings. Methods: A literature review using a systematic approach was conducted. Electronic searches were performed in the following databases; PubMed Central, CINAHL Plus and Science Direct. Results: 48 NSTs and 110 validation studies were identified. Validation results vary greatly, with sensitivities and specificities ranging from 0.06–1.0 and 0.12–1.0 respectively. Poor study designs (i.e. tools not validated against an appropriate ‘gold standard’ method) were apparent for many of the tools. Twenty-three (47%) tools were designed specifically for older adults (e.g. MNA-SF) and twenty-five (53%) were designed for general adult use (e.g. NRS-2002, MUST). Furthermore, each tool included different parameters (54 different parameters were identified), some of which are considered more appropriate for malnutrition screening in older adults (e.g. weight loss) than others (e.g. serum albumin). Conclusion: Although many NSTs are recommended for use in older adults, their derivation and/or validation in younger populations mean that they may not be reliable in older adults or in settings outside those in which they have been validated. Further work of the MaNuEL project involves the creation of a scoring system to determine the most appropriate NSTs for use in older adults. This work was supported by funding from the Department of Agriculture, Food and the Marine and Health Research Board through the Joint Programming Initiative – A Healthy Diet for a Healthy Life (JPI HDHL) Knowledge Hub on Malnutrition in the Elderly (MaNuEL). Disclosure of Interest: None declared.
PT01.4 ENERGY AND MACRONUTRIENT INTAKE AT AGE 70 IS NOT ASSOCIATED WITH PREVALENCE OF SARCOPENIA AT AGE 88 M. Karlsson1 *, T. Cederholm1, W. Becker1, P. Sjogren1. 1 Department of Public Health and Caring Sciences, Uppsala University, Clinical Nutrition and Metabolism, Uppsala, Sweden
Poster tours Rationale: An unfavorable change in body composition with increasing age, i.e. loss of muscle mass, will influence functionality and risk of developing sarcopenia. However there are indications that macronutrient (e.g. protein) may affect protein turn-over in skeletal muscle. Against this background we examined how energy and macronutrient intake at age 70 was associated to sarcopenia approximately 18 years later. Methods: The participants are part of a larger study population of men (Uppsala Longitudinal Study of Adult Men) born between 1920 and 1924, living in Uppsala county, Sweden. Dietary intake at age 70 was determined by a 7-day estimated food record. Dual-energy X-ray absorptiometry (DXA), gaitspeed and handgrip strength were examined approximately 18 years later. The criteria established by the European Working Group on Sarcopenia in Older People were used to define sarcopenia. T-test was used for statistical analysis. Results: A total of 255 elderly men, identified as adequate dietary reporters, (mean age 86.6 ± 1.0 year, BMI 25.6 ± 3.5 kg/m2 and weight 76.3 ± 11.4 kg) were include of which 54 men (21.2%) were defined as sarcopenic (mean age 86.6 ± 1.0 year, BMI 23.4 ± 2.6 kg/m2 and weight 67.9 ± 9.1 kg). The nonsarcopenic men (n = 201, mean age 86.6 ± 1.0 year, BMI 26.2 ± 3.4 kg/m2 and weight 78.6 ± 10.9 kg) had a significantly higher ( p = 0.0001) BMI and body weight compared to the sarcopenic men. There was no significant difference in the intake of energy or macronutrients between the sarcopenic (energy 1,803 ± 447 kcal, fat 70.8 ± 23.1 g, carbohydrate 216.5 ± 59.8 g and protein 68.2 ± 17.3 g) and non-sarcopenic men (energy 1,870 ± 439 kcal, fat 73.3 ± 20.5 g, carbohydrate 225.7 ± 60.4 g and protein 69.5 ± 15.8 g). Conclusion: We found no correlation between energy or macronutrient intake at age 70 and the prevalence of sarcopenia 18 years later in this cohort of community dwelling men. Disclosure of Interest: None declared.
PT01.5 LONGITUDINAL ASSOCIATIONS BETWEEN VITAMIN D METABOLITES AND SARCOPENIA IN OLDER AUSTRALIAN MEN: THE CONCORD HEALTH AND AGEING IN MEN PROJECT V. Hirani1 *, F. Blyth2, V. Naganathan2, R. Cumming3. 1School of Life and Environmental Sciences, Faculty of Science, 2Concord Clinical School, 3School of Public Health, University of Sydney, Sydney, Australia Rationale: Sarcopenia, an age associated reduction in skeletal muscle mass and strength as well as hypovitaminosis D are major clinical problems among older people. The aims of this study are to explore the associations between serum 25hydroxyvitamin D (25D) and 1,25-dihydroxyvitamin D (1,25D) levels at baseline and incidence of sarcopenia over time in older Australian community-dwelling older men. Methods: Men aged ≥70 years (2005–07) from the Concord Health and Ageing in Men Project were assesed at baseline, two year and five year follow up. The main outcome measurement was the incidence of sarcopenia defined as appendicular lean mass adjusted for body mass index <0.789 and grip strength < 26.0 kg using the Foundation for the National Institutes of Health definition of sarcopenia. Serum 25D and 1,25D levels
PT01.3 A REVIEW OF NUTRITIONAL SCREENING TOOLS USED IN OLDER ADULTS L. C. Power1,2 *, D. Mullally1,2, M. A. de van der Schueren3,4, E. R. Gibney2,5, M. Clarke2,5, L. A. Bardon2,5, C. Corish1,2, on behalf of the MaNuEL Consortium. 1School of Public Health, Physiotherapy and Sports Science, 2Institute of Food and Health, University College Dublin, Dublin, Ireland, 3 Department of Nutrition and Dietetics, VU University Medical Centre, Amsterdam, 4Department of Nutrition and Health, HAN University of Applied Sciences, Nijmegen, Netherlands, 5 Department of Agriculture and Food Science, University College Dublin, Dublin, Ireland Rationale: Many nutritional screening tools (NSTs) are used in older adults (>65 years), each containing a diverse range of parameters and validated against different standards. An objective of the EU Malnutrition in the Elderly Knowledge hub (MaNuEL) project is to review existing NSTs used in older adults in various healthcare settings. Methods: A literature review using a systematic approach was conducted. Electronic searches were performed in the following databases; PubMed Central, CINAHL Plus and Science Direct. Results: 48 NSTs and 110 validation studies were identified. Validation results vary greatly, with sensitivities and specificities ranging from 0.06–1.0 and 0.12–1.0 respectively. Poor study designs (i.e. tools not validated against an appropriate ‘gold standard’ method) were apparent for many of the tools. Twenty-three (47%) tools were designed specifically for older adults (e.g. MNA-SF) and twenty-five (53%) were designed for general adult use (e.g. NRS-2002, MUST). Furthermore, each tool included different parameters (54 different parameters were identified), some of which are considered more appropriate for malnutrition screening in older adults (e.g. weight loss) than others (e.g. serum albumin). Conclusion: Although many NSTs are recommended for use in older adults, their derivation and/or validation in younger populations mean that they may not be reliable in older adults or in settings outside those in which they have been validated. Further work of the MaNuEL project involves the creation of a scoring system to determine the most appropriate NSTs for use in older adults. This work was supported by funding from the Department of Agriculture, Food and the Marine and Health Research Board through the Joint Programming Initiative – A Healthy Diet for a Healthy Life (JPI HDHL) Knowledge Hub on Malnutrition in the Elderly (MaNuEL). Disclosure of Interest: None declared.
PT01.4 ENERGY AND MACRONUTRIENT INTAKE AT AGE 70 IS NOT ASSOCIATED WITH PREVALENCE OF SARCOPENIA AT AGE 88 M. Karlsson1 *, T. Cederholm1, W. Becker1, P. Sjogren1. 1 Department of Public Health and Caring Sciences, Uppsala University, Clinical Nutrition and Metabolism, Uppsala, Sweden
Poster tours Rationale: An unfavorable change in body composition with increasing age, i.e. loss of muscle mass, will influence functionality and risk of developing sarcopenia. However there are indications that macronutrient (e.g. protein) may affect protein turn-over in skeletal muscle. Against this background we examined how energy and macronutrient intake at age 70 was associated to sarcopenia approximately 18 years later. Methods: The participants are part of a larger study population of men (Uppsala Longitudinal Study of Adult Men) born between 1920 and 1924, living in Uppsala county, Sweden. Dietary intake at age 70 was determined by a 7-day estimated food record. Dual-energy X-ray absorptiometry (DXA), gaitspeed and handgrip strength were examined approximately 18 years later. The criteria established by the European Working Group on Sarcopenia in Older People were used to define sarcopenia. T-test was used for statistical analysis. Results: A total of 255 elderly men, identified as adequate dietary reporters, (mean age 86.6 ± 1.0 year, BMI 25.6 ± 3.5 kg/m2 and weight 76.3 ± 11.4 kg) were include of which 54 men (21.2%) were defined as sarcopenic (mean age 86.6 ± 1.0 year, BMI 23.4 ± 2.6 kg/m2 and weight 67.9 ± 9.1 kg). The nonsarcopenic men (n = 201, mean age 86.6 ± 1.0 year, BMI 26.2 ± 3.4 kg/m2 and weight 78.6 ± 10.9 kg) had a significantly higher ( p = 0.0001) BMI and body weight compared to the sarcopenic men. There was no significant difference in the intake of energy or macronutrients between the sarcopenic (energy 1,803 ± 447 kcal, fat 70.8 ± 23.1 g, carbohydrate 216.5 ± 59.8 g and protein 68.2 ± 17.3 g) and non-sarcopenic men (energy 1,870 ± 439 kcal, fat 73.3 ± 20.5 g, carbohydrate 225.7 ± 60.4 g and protein 69.5 ± 15.8 g). Conclusion: We found no correlation between energy or macronutrient intake at age 70 and the prevalence of sarcopenia 18 years later in this cohort of community dwelling men. Disclosure of Interest: None declared.
PT01.5 LONGITUDINAL ASSOCIATIONS BETWEEN VITAMIN D METABOLITES AND SARCOPENIA IN OLDER AUSTRALIAN MEN: THE CONCORD HEALTH AND AGEING IN MEN PROJECT V. Hirani1 *, F. Blyth2, V. Naganathan2, R. Cumming3. 1School of Life and Environmental Sciences, Faculty of Science, 2Concord Clinical School, 3School of Public Health, University of Sydney, Sydney, Australia Rationale: Sarcopenia, an age associated reduction in skeletal muscle mass and strength as well as hypovitaminosis D are major clinical problems among older people. The aims of this study are to explore the associations between serum 25hydroxyvitamin D (25D) and 1,25-dihydroxyvitamin D (1,25D) levels at baseline and incidence of sarcopenia over time in older Australian community-dwelling older men. Methods: Men aged ≥70 years (2005–07) from the Concord Health and Ageing in Men Project were assesed at baseline, two year and five year follow up. The main outcome measurement was the incidence of sarcopenia defined as appendicular lean mass adjusted for body mass index <0.789 and grip strength < 26.0 kg using the Foundation for the National Institutes of Health definition of sarcopenia. Serum 25D and 1,25D levels