- Email: [email protected]
PT166 How Many Dialysis Patients Receive Transplantation After Achieving Eligibility By Undergoing Coronary Artery Bypass Grafting?
Hospital, prior to potential future renal transplant. Mortality and rate of subsequent RTX were assessed. Results: Isolated CABG was performed in 90 dialysis patients, with 45 (50%) considered potential future RTX candidates. Of these 20 (44%) were asymptomatic, with 4 (20%) receiving subsequent RTX, 10 (50%) removed from the transplant list or died, and 6 (30%) patients continued to await renal transplantation as at 1st July 2013. In symptomatic dialysis patients eligible for RTX, 3 (12%) received RTX, 17 (68%) were removed from the transplant list or died and 5 (20%) continue to await renal transplantation. There was no difference between asymptomatic patients and symptomatic patients for rate of transplantation(p<0.68) and rate of removal from transplant list due to ineligibility or death(p<0.24). Median follow-up time for asymptomatic and symptomatic patients was 1487 and 1711 days respectively. Mortality at 30 days was 5% and 12% for asymptomatic and symptomatic patients respectively (p<0.62). Conclusion: In dialysis patients, both symptomatic and asymptomatic, only a small proportion undergo subsequent renal transplantation following CABG, with more than half becoming ineligible. Strict selection criteria is important to ensure the appropriate patients undergo CABG prior to RTX. Disclosure of Interest: None Declared
PT167 Health-Related Quality of Life Five Years After Coronary Artery Bypass Graft Surgery Josip Vincelj*1, Tihana Jendricko2, Lela Bitar3, Mario Udovicic1, Mladen Petrovecki4 Cardiology, University Hospital Dubrava, 2Pshychiatry, University Psychiatric Hospital Vrapce, 3 Internal medicine, University Hospital Center Zagreb, 4Laboratory Diagnostics, University Hospital Dubrava, Zagreb, Croatia
1
Conclusion: In non-selected ACS patients, lab index has reasonable predictive power for the 30-day and 1-year mortality and performed better than GRACE score for STEMI patients at both time points. Disclosure of Interest: None Declared
Introduction: Coronary artery bypass graft (CABG) surgery is performed to reduce cardiac mortality and to relieve patients’ symptoms of coronary artery disease and to prolong lives. Health related quality of life (HRQL) is a sensitive tool to asses the outcome of coronary artery bypass graft surgery in terms of patient’s postoperative functionality. Objectives: The aim of our study was to determine HRQL of our patients and to determine variables that have an impact on impaired or unimpaired HRQL, based on the completion of the short form health survey questionnaire (SF-36). Methods: Eligible subjects were adults who underwent CABG surgery in University Hospital Dubrava, Zagreb during 2007. HRQL was assessed by the Short-Form 36 questionnaire. Demographic data (age, gender, BMI, smoking status, family history), medical characteristics (cholesterol, LDL and blood glucose level) and presence of co-morbidity (myocardial infarction, cerebrovascular disease, arterial hypertension, hyperlipidemia and diabetes mellitus) were collected. Results: The study population included 140 patients with age range between 43-83 years, mean 61. 99.27. The study population had a significant burden of morbidity, including hyperlipidemia 82%, hypertension 74% and myocardial infarction 59%. Good or excellent health was reported by 62% of subjects. Limited performance during vigorous activities was reported by 62.9% of our subjects, while only 20% of them reporetd limited performance during moderate activities. Also 60.7% of our subjects reported that they accomplished less than they would like. Physical health or emotional problems didn’t interfere with their normal social activities in 73%. Based on SF-36 answers we identified two groups of subjects, first with unimpaired HRQL and second with impaired HRQL after CABG surgery. We have found that gender, age, co-morbidity and smoking status were no significant predictors of group membership (p>0.1). However, some of the variables were associated with specific HRQL outcomes. For example, myocardial infarction was a significant predictor for decreased work ability and difficulties in performing everyday tasks (p<0.1). Conclusion: Overall HRQL is unimpaired for most of the patients. There were no significant predictors for impaired or unimpaired HRQL. We identified variables that are associated with specific HRQL outcomes, which could be used as preoperative assessment and to improve patients’ outcomes. Disclosure of Interest: None Declared
PT168 Predictors of Thromboischemic Events In Early Postoperative Period of Coronary Artery Bypass Grafting
PT166 How Many Dialysis Patients Receive Transplantation After Achieving Eligibility By Undergoing Coronary Artery Bypass Grafting? Janarthanan Sathananthan*1, Helen Pilmore2, Janak De Zoysa3, Peter Ruygrok1 1 Cardiology, Greenlane Cardiovascular Service, 2Department of Renal Medicine, Auckland District Health Board, 3Department of Renal Medicine, Waitemata District Health Board, Auckland, New Zealand Introduction: In some centres dialysis patients undergo coronary artery bypass grafting (CABG) to achieve eligibility for potential future renal transplantation (RTX). Objectives: We wished to determine mortality and rate of renal transplantation following CABG in this patient population. Methods: All dialysis patients were identified, both symptomatic and asymptomatic, who underwent isolated CABG from January 2005 to December 2012, in Auckland City
GHEART Vol 9/1S/2014
j
March, 2014
j
POSTER/2014 WCC Posters
Sergey Altarev*1, Olga Barbarash2, Yulia Podaneva2 Pehabilitation Laboratory, 2Research Institute of Complex Issues of Cardiovascular Diseases, Kemerovo, Russian Federation
1
Introduction: Although contemporary invasive cardiology and cardiac surgery have achieved great success, perioperative periods including after coronary artery bypass grafting (CABG) are still complicated with cerebral and cardiac ischemic events. Objectives: Determine predictors of thromboischemic events in the early postoperative period after CABG. Methods: We analyzed the data of the CABG Registry which had been carried out in the Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, Russian Federation, in 2009. The Registry contains the data of all the patients undergone CABG in the Institute in 2009. Ischemic events included fatal and nonfatal myocardial infarctions and ischemic strokes. All the statistical calculations were performed using
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POSTER ABSTRACTS
ExTRACT-TIMI25) and was shown to be a powerful predictor of death in STEMI separately and with TIMI risk score Objectives: To test whether the lab index can predict short and intermediate-term mortality in real world all ACS patients separately and in combination with GRACE score. Methods: The study population consisted of 7929 consecutive patients enrolled in the Gulf-RACE 2 registry from 6 gulf countries in the Middle East. Lab index was calculated for every patient according to the formula (15 - Hgb + [100- CrCl/8]). C-statistic was used to test the predictive power of lab index for 30-day and 1-year mortality in the entire ACS cohort, and in STEMI and non-STEMI groups, and was compared to GRACE score. We also tested whether the addition of the lab index to GRACE score improves its predictive power Results: The predictive power of the lab index for the 30-day mortality was reasonably good with C-statistic for all ACS patients 0.71 (95% CI 0.69-0.74), STEMI 0.75 (95% CI 0.71-0.77) and non-STEMI 0.70 (95% CI 0.66-0.74). Similarly, the predictive power for the1-year mortality was good; C-statistic for all ACS patients 0.72 (95% CI 0.70-0.74), STEMI 0.74 (95% CI 0.71-0.76) and non-STEMI 0.71 (95% CI 0.680.71). Overall, the lab index was as good as GRACE score in predicting 30-day and 1-year mortality, however, it performed better than GRACE score for STEMI patients with C-statistic of 0.75 vs. 0.71 at 30 days (P¼ 0.02) and 0.74 vs. 0.69 at 1 year (P¼ 0.001). The low and intermediate GRACE risk groups showed significant variation in the predicted risk of death when stratified by different levels of lab index.
PT167 Health-Related Quality of Life Five Years After Coronary Artery Bypass Graft Surgery Josip Vincelj*1, Tihana Jendricko2, Lela Bitar3, Mario Udovicic1, Mladen Petrovecki4 Cardiology, University Hospital Dubrava, 2Pshychiatry, University Psychiatric Hospital Vrapce, 3 Internal medicine, University Hospital Center Zagreb, 4Laboratory Diagnostics, University Hospital Dubrava, Zagreb, Croatia
1
Conclusion: In non-selected ACS patients, lab index has reasonable predictive power for the 30-day and 1-year mortality and performed better than GRACE score for STEMI patients at both time points. Disclosure of Interest: None Declared
Introduction: Coronary artery bypass graft (CABG) surgery is performed to reduce cardiac mortality and to relieve patients’ symptoms of coronary artery disease and to prolong lives. Health related quality of life (HRQL) is a sensitive tool to asses the outcome of coronary artery bypass graft surgery in terms of patient’s postoperative functionality. Objectives: The aim of our study was to determine HRQL of our patients and to determine variables that have an impact on impaired or unimpaired HRQL, based on the completion of the short form health survey questionnaire (SF-36). Methods: Eligible subjects were adults who underwent CABG surgery in University Hospital Dubrava, Zagreb during 2007. HRQL was assessed by the Short-Form 36 questionnaire. Demographic data (age, gender, BMI, smoking status, family history), medical characteristics (cholesterol, LDL and blood glucose level) and presence of co-morbidity (myocardial infarction, cerebrovascular disease, arterial hypertension, hyperlipidemia and diabetes mellitus) were collected. Results: The study population included 140 patients with age range between 43-83 years, mean 61. 99.27. The study population had a significant burden of morbidity, including hyperlipidemia 82%, hypertension 74% and myocardial infarction 59%. Good or excellent health was reported by 62% of subjects. Limited performance during vigorous activities was reported by 62.9% of our subjects, while only 20% of them reporetd limited performance during moderate activities. Also 60.7% of our subjects reported that they accomplished less than they would like. Physical health or emotional problems didn’t interfere with their normal social activities in 73%. Based on SF-36 answers we identified two groups of subjects, first with unimpaired HRQL and second with impaired HRQL after CABG surgery. We have found that gender, age, co-morbidity and smoking status were no significant predictors of group membership (p>0.1). However, some of the variables were associated with specific HRQL outcomes. For example, myocardial infarction was a significant predictor for decreased work ability and difficulties in performing everyday tasks (p<0.1). Conclusion: Overall HRQL is unimpaired for most of the patients. There were no significant predictors for impaired or unimpaired HRQL. We identified variables that are associated with specific HRQL outcomes, which could be used as preoperative assessment and to improve patients’ outcomes. Disclosure of Interest: None Declared
PT168 Predictors of Thromboischemic Events In Early Postoperative Period of Coronary Artery Bypass Grafting
PT166 How Many Dialysis Patients Receive Transplantation After Achieving Eligibility By Undergoing Coronary Artery Bypass Grafting? Janarthanan Sathananthan*1, Helen Pilmore2, Janak De Zoysa3, Peter Ruygrok1 1 Cardiology, Greenlane Cardiovascular Service, 2Department of Renal Medicine, Auckland District Health Board, 3Department of Renal Medicine, Waitemata District Health Board, Auckland, New Zealand Introduction: In some centres dialysis patients undergo coronary artery bypass grafting (CABG) to achieve eligibility for potential future renal transplantation (RTX). Objectives: We wished to determine mortality and rate of renal transplantation following CABG in this patient population. Methods: All dialysis patients were identified, both symptomatic and asymptomatic, who underwent isolated CABG from January 2005 to December 2012, in Auckland City
GHEART Vol 9/1S/2014
j
March, 2014
j
POSTER/2014 WCC Posters
Sergey Altarev*1, Olga Barbarash2, Yulia Podaneva2 Pehabilitation Laboratory, 2Research Institute of Complex Issues of Cardiovascular Diseases, Kemerovo, Russian Federation
1
Introduction: Although contemporary invasive cardiology and cardiac surgery have achieved great success, perioperative periods including after coronary artery bypass grafting (CABG) are still complicated with cerebral and cardiac ischemic events. Objectives: Determine predictors of thromboischemic events in the early postoperative period after CABG. Methods: We analyzed the data of the CABG Registry which had been carried out in the Research Institute for Complex Issues of Cardiovascular Diseases, Kemerovo, Russian Federation, in 2009. The Registry contains the data of all the patients undergone CABG in the Institute in 2009. Ischemic events included fatal and nonfatal myocardial infarctions and ischemic strokes. All the statistical calculations were performed using
e199
POSTER ABSTRACTS
ExTRACT-TIMI25) and was shown to be a powerful predictor of death in STEMI separately and with TIMI risk score Objectives: To test whether the lab index can predict short and intermediate-term mortality in real world all ACS patients separately and in combination with GRACE score. Methods: The study population consisted of 7929 consecutive patients enrolled in the Gulf-RACE 2 registry from 6 gulf countries in the Middle East. Lab index was calculated for every patient according to the formula (15 - Hgb + [100- CrCl/8]). C-statistic was used to test the predictive power of lab index for 30-day and 1-year mortality in the entire ACS cohort, and in STEMI and non-STEMI groups, and was compared to GRACE score. We also tested whether the addition of the lab index to GRACE score improves its predictive power Results: The predictive power of the lab index for the 30-day mortality was reasonably good with C-statistic for all ACS patients 0.71 (95% CI 0.69-0.74), STEMI 0.75 (95% CI 0.71-0.77) and non-STEMI 0.70 (95% CI 0.66-0.74). Similarly, the predictive power for the1-year mortality was good; C-statistic for all ACS patients 0.72 (95% CI 0.70-0.74), STEMI 0.74 (95% CI 0.71-0.76) and non-STEMI 0.71 (95% CI 0.680.71). Overall, the lab index was as good as GRACE score in predicting 30-day and 1-year mortality, however, it performed better than GRACE score for STEMI patients with C-statistic of 0.75 vs. 0.71 at 30 days (P¼ 0.02) and 0.74 vs. 0.69 at 1 year (P¼ 0.001). The low and intermediate GRACE risk groups showed significant variation in the predicted risk of death when stratified by different levels of lab index.