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PT326 Basic Life Support Knowledge and Skills of General Dental Practitioners to Perform Cardiopulmonary Resuscitation
POSTER ABSTRACTS
synovium, glomerulus which may further leads to complex diseases. The web of metabolic disorders leads to metabolic syndrome which is associated with high risk of diabetes. Objectives: This cross-sectional study emphasizes the association of circulating levels of MMP 2,4,9 in metabolic syndrome (MetS) with coronary artery disease (CAD). Methods: The age, sex matched 200 patients recruited with 70 subjects having only metabolic syndrome, 70 subjects having both metabolic and 60 healthy controls. The study subjects devided in three groups Gr 1 MetS, Gr 2 Mets + CAD, Gr 3 Control. Blood and serum samples of patients and healthy controls were collected. To screen the patients with MetS, IDF criteria and biochemical assays were used while CAD patients were screened. The circulating level of MMP 2,4,9 in serum was analyzed by ELISA in all patients and control. Results: We found the activity of MMP2 and 9 enzymes were higher (p < 0.05) in patients having MetS + CAD as compared to MetS group. The activity of MMP 9 was higher in Gr 1 as compared to Gr3 (p < 0.001) while difference between Gr 2 and Gr 3 was also significantly altered (p < 0.05). There was no change observed in MMP 4 activity. Conclusion: Our findings suggests that serum MMP 9 level may have significant potential to work as a biomarker in diagnosis of Mets and CAD. This may provide a novel target for new therapeutic measures for metabolic disorders and cardiovascular events. Disclosure of Interest: None Declared
PT319 The Association Between Oral Glucose Test Tolerance Test, BMI and Physical Fitness Among 7 to 10 Years Children in Ellisras Rural Areas, South Africa M. Sekhotha*1, K. Monyeki1 Physiology, University of Limpopo, Sovenga, South Africa
1
Introduction: Most studies had shown that poor physical fitness and impaired glucose tolerance can lead to late development of insulin resistance and diabetes mellitus. Objectives: The purpose of this study was to investigate the relationship between oral glucose tolerance test, BMI and physical fitness among Ellisras rural children age 7 to 10 years old. Methods: Oral glucose tolerance test (OGTT), BMI and physical fitness were conducted amongst a total of 417 who are part of Ellisras rural children from age 7 to 10 years following a standard procedure Linear regression was used to determine the relationship between oral glucose tolerance test, BMI and physical fitness. Results: There was a relationship between OGTT and with plate tapping (b ¼ 0.091) at 95% CI -0.014 to 0.014 adjusted for age and gender (-0.02 to 0.010). But there was not relationship between BMI and Glucose tolerance test. Conclusion: As both physical fitness does not relationship OGTT and BMI this illustrate that the might not be any danger of developing any insulin resistance in the future. Further studies are need to look at this relation in the near future. Disclosure of Interest: None Declared PT325 Public Knowledge Concerning Cardiopulmonary Resuscitation and Automated External Defibrillator Skills in Lithuania P. Serpytis*1, T. Tamosiunas2, A. Slusniene3, G. Kezyte4, I. Urbanaviciute1,4, R. Serpytis1,2, A. Laucevicius2 1 Emergency Department, 2Cardiology Department, Vilnius University Hospital Santariskiu Klinikos, 3Centre for Innovative Medicine, 4Faculty of medicine, Vilnius University, Vilnius, Lithuania Introduction: Cardiovascular disease (CVD) is the leading cause of mortality worldwide. 65 % of first registered rhythm after cardiac arrest is ventricular fibrillation (VF) which can be restored to sinus rhythm by defibrillation. European Resuscitation Council guidelines (2015) highlights the importance of Automated external defibrillator (AED) and encourages further AED program development and device installation in public places. Objectives: To assess public knowledge about cardiopulmonary resuscitation (CPR) and capability of AED use in 5 biggest Lithuanian cities. Methods: Anonymous survey was conducted in 2015 from January to March in public areas (shopping malls, stations, city squares). Adults (age range 18-65 years) who claimed to have knowledge about CPR were interviewed. When estimating the number of respondents in each city it was attempted to maintain proportion of the citizens corresponding the city’s population. Results: 130 (76.9%) of the respondents described their knowledge about CPR as inadequate. In a hipothetical 3-step situation where a person clenches fists over his chest and falls only 16.6% of respondents would act correctly according to guidelines. Only 29% (49) knew what AED was, those aware of AED - almost all correctly stated the principle of managing the device and indications of its usage. The main sources of information regarding AED: training in the office 28.6% (14), television 28.6% (14), driving courses 22.4% (11); about CPR - driving courses 70.4% (119), school 46.7% (79), television 26% (44) and training in the office 24.9% (42). 81.6% of respondents would participate in CPR and AED courses, if they were free of charge. Conclusion: Lithuanian people knowledge about CPR is insufficient, only every third person knows what AEDs are. Community education and training on CPR and AEDs use are needed. Majority of respondents would attend CPR and AED training if it would be free. Disclosure of Interest: None Declared
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PT326 Basic Life Support Knowledge and Skills of General Dental Practitioners to Perform Cardiopulmonary Resuscitation S. Timerman1, L. Timerman*2, V. C. Conrado2, A. C. P. de Andrade2, G. A. Angelis2, T. Facholi3 1 Medicine and Health Science, Laureate International Universities, 2Dentistry Department, Dante Pazzanese Institute of Cardiology, 3LTSEC, Heart Institute (InCor) HC FMUSP, Sao Paulo, Brazil Introduction: When cardiopulmonary arrest occurs, the dentist’s ability to perform cardiopulmonary resuscitation (CPR) is the most important factor to minimize morbidity and mortality. Objectives: This study assessed the basic life support (BLS) knowledge and performance of general dental practitioners in Sao Paulo, Brazil. Methods: The participants in the study were 128 general dental practitioners who were chosen randomly. Their CPR knowledge was evaluated by verbal questions and their CPR skills were determined by CPR execution on a special manikin. Nearly 39% of dentists answered none of the questions and only 2.50% answered all of the questions correctly. 66 dentists had been participated CPR course after graduation. Results: There was a significant difference between dentists who participated in CPR training course and those that did not participate (P value ¼ 0.000). Only 3.75% (n ¼ 3) were able to perform CPR properly. Conclusion: The results showed that the amount of CPR knowledge and skills were low in participated general dental practitioners. However, CPR training courses after graduation increased the amount of knowledge significantly, thus, retraining CPR courses is necessary for dentists. Disclosure of Interest: None Declared PT327 The Impact of Augmentation Index on Renal Function Decline in a Chinese Community-Based Population Without Chronic Kidney Disease B. Zheng1, L. Qi1, F. Fan1, J. Jia1, H. Li2, J. Li1, Y. Zhang*1, Y. Huo1 1 Cardiology, 2Clinical laboratory, Peking University First Hospital, Beijing, China Introduction: Increased augmentation index (AIx) are associated with a more rapid progression of decline of renal function in patients with chronic kidney disease (CKD). However, whether AIx could affect the future kidney outcome among patients without CKD still remains uncertain. Objectives: We aimed to investigate the impact of baseline AIx on the kidney function decline among the population without baseline CKD. Methods: A total of 3164 Chinese subjects with estimated glomerular filtration rate (eGFR) > 60ml/min/1.73 m2 from an atherosclerosis cohort were included in our analysis. Baseline AIx normalized to heart rate of 75 beats per minute (AIp75) was obtained using HEM-9000AI (Omron Healthcare Co., Ltd.). EGFR of both baseline and follow-up were calculated using CKD-EPI formula. ). Multivariate regression models were used to evaluate association of AIp75 and rapid kidney function decline defined as a drop in GFR category accompanied by a 25% or a sustained decline in eGFR of more than 5 ml/min/1.73 m2/year. Results: Subjects were 56.6 8.5 years old, 36% were male, and 49.3% had hypertension. Mean (SD) baseline AIp75 was 80.5 12.0 Mean (SD) and baseline eGFR was 101.2 10.6 ml/min/1.73 m2. After 2.3 years follow-up, the incidence of rapid decline was 7.3%. AIp75 (per each 10 increase) tended to be associated with rapid kidney function decline (OR, 95% CI, 1.13, 0.977-1.27, p¼0.056) after adjustment for demographic variables, risk factors, comorbidities and baseline eGFR. When stratified according to age, gender, diabetes, and eGFR at baseline respectively, AIp75 was an independent predictor for rapid renal function decline in subgroups of the elderly, female, diabetes and mildly impaired renal function (eGFR 60-90 ml/min/1.73 m2) (Figure 1).
Conclusion: Augmentation index might be a predictive risk factor related to early renal function decline in Chinese community-based population without chronic kidney disease, especially in elderly, female, diabetic population and patients with slightly reduction of kidney function. Disclosure of Interest: None Declared
GHEART Vol 11/2S/2016
j
June, 2016
j
POSTER/WCC_2016-POSTERS
synovium, glomerulus which may further leads to complex diseases. The web of metabolic disorders leads to metabolic syndrome which is associated with high risk of diabetes. Objectives: This cross-sectional study emphasizes the association of circulating levels of MMP 2,4,9 in metabolic syndrome (MetS) with coronary artery disease (CAD). Methods: The age, sex matched 200 patients recruited with 70 subjects having only metabolic syndrome, 70 subjects having both metabolic and 60 healthy controls. The study subjects devided in three groups Gr 1 MetS, Gr 2 Mets + CAD, Gr 3 Control. Blood and serum samples of patients and healthy controls were collected. To screen the patients with MetS, IDF criteria and biochemical assays were used while CAD patients were screened. The circulating level of MMP 2,4,9 in serum was analyzed by ELISA in all patients and control. Results: We found the activity of MMP2 and 9 enzymes were higher (p < 0.05) in patients having MetS + CAD as compared to MetS group. The activity of MMP 9 was higher in Gr 1 as compared to Gr3 (p < 0.001) while difference between Gr 2 and Gr 3 was also significantly altered (p < 0.05). There was no change observed in MMP 4 activity. Conclusion: Our findings suggests that serum MMP 9 level may have significant potential to work as a biomarker in diagnosis of Mets and CAD. This may provide a novel target for new therapeutic measures for metabolic disorders and cardiovascular events. Disclosure of Interest: None Declared
PT319 The Association Between Oral Glucose Test Tolerance Test, BMI and Physical Fitness Among 7 to 10 Years Children in Ellisras Rural Areas, South Africa M. Sekhotha*1, K. Monyeki1 Physiology, University of Limpopo, Sovenga, South Africa
1
Introduction: Most studies had shown that poor physical fitness and impaired glucose tolerance can lead to late development of insulin resistance and diabetes mellitus. Objectives: The purpose of this study was to investigate the relationship between oral glucose tolerance test, BMI and physical fitness among Ellisras rural children age 7 to 10 years old. Methods: Oral glucose tolerance test (OGTT), BMI and physical fitness were conducted amongst a total of 417 who are part of Ellisras rural children from age 7 to 10 years following a standard procedure Linear regression was used to determine the relationship between oral glucose tolerance test, BMI and physical fitness. Results: There was a relationship between OGTT and with plate tapping (b ¼ 0.091) at 95% CI -0.014 to 0.014 adjusted for age and gender (-0.02 to 0.010). But there was not relationship between BMI and Glucose tolerance test. Conclusion: As both physical fitness does not relationship OGTT and BMI this illustrate that the might not be any danger of developing any insulin resistance in the future. Further studies are need to look at this relation in the near future. Disclosure of Interest: None Declared PT325 Public Knowledge Concerning Cardiopulmonary Resuscitation and Automated External Defibrillator Skills in Lithuania P. Serpytis*1, T. Tamosiunas2, A. Slusniene3, G. Kezyte4, I. Urbanaviciute1,4, R. Serpytis1,2, A. Laucevicius2 1 Emergency Department, 2Cardiology Department, Vilnius University Hospital Santariskiu Klinikos, 3Centre for Innovative Medicine, 4Faculty of medicine, Vilnius University, Vilnius, Lithuania Introduction: Cardiovascular disease (CVD) is the leading cause of mortality worldwide. 65 % of first registered rhythm after cardiac arrest is ventricular fibrillation (VF) which can be restored to sinus rhythm by defibrillation. European Resuscitation Council guidelines (2015) highlights the importance of Automated external defibrillator (AED) and encourages further AED program development and device installation in public places. Objectives: To assess public knowledge about cardiopulmonary resuscitation (CPR) and capability of AED use in 5 biggest Lithuanian cities. Methods: Anonymous survey was conducted in 2015 from January to March in public areas (shopping malls, stations, city squares). Adults (age range 18-65 years) who claimed to have knowledge about CPR were interviewed. When estimating the number of respondents in each city it was attempted to maintain proportion of the citizens corresponding the city’s population. Results: 130 (76.9%) of the respondents described their knowledge about CPR as inadequate. In a hipothetical 3-step situation where a person clenches fists over his chest and falls only 16.6% of respondents would act correctly according to guidelines. Only 29% (49) knew what AED was, those aware of AED - almost all correctly stated the principle of managing the device and indications of its usage. The main sources of information regarding AED: training in the office 28.6% (14), television 28.6% (14), driving courses 22.4% (11); about CPR - driving courses 70.4% (119), school 46.7% (79), television 26% (44) and training in the office 24.9% (42). 81.6% of respondents would participate in CPR and AED courses, if they were free of charge. Conclusion: Lithuanian people knowledge about CPR is insufficient, only every third person knows what AEDs are. Community education and training on CPR and AEDs use are needed. Majority of respondents would attend CPR and AED training if it would be free. Disclosure of Interest: None Declared
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PT326 Basic Life Support Knowledge and Skills of General Dental Practitioners to Perform Cardiopulmonary Resuscitation S. Timerman1, L. Timerman*2, V. C. Conrado2, A. C. P. de Andrade2, G. A. Angelis2, T. Facholi3 1 Medicine and Health Science, Laureate International Universities, 2Dentistry Department, Dante Pazzanese Institute of Cardiology, 3LTSEC, Heart Institute (InCor) HC FMUSP, Sao Paulo, Brazil Introduction: When cardiopulmonary arrest occurs, the dentist’s ability to perform cardiopulmonary resuscitation (CPR) is the most important factor to minimize morbidity and mortality. Objectives: This study assessed the basic life support (BLS) knowledge and performance of general dental practitioners in Sao Paulo, Brazil. Methods: The participants in the study were 128 general dental practitioners who were chosen randomly. Their CPR knowledge was evaluated by verbal questions and their CPR skills were determined by CPR execution on a special manikin. Nearly 39% of dentists answered none of the questions and only 2.50% answered all of the questions correctly. 66 dentists had been participated CPR course after graduation. Results: There was a significant difference between dentists who participated in CPR training course and those that did not participate (P value ¼ 0.000). Only 3.75% (n ¼ 3) were able to perform CPR properly. Conclusion: The results showed that the amount of CPR knowledge and skills were low in participated general dental practitioners. However, CPR training courses after graduation increased the amount of knowledge significantly, thus, retraining CPR courses is necessary for dentists. Disclosure of Interest: None Declared PT327 The Impact of Augmentation Index on Renal Function Decline in a Chinese Community-Based Population Without Chronic Kidney Disease B. Zheng1, L. Qi1, F. Fan1, J. Jia1, H. Li2, J. Li1, Y. Zhang*1, Y. Huo1 1 Cardiology, 2Clinical laboratory, Peking University First Hospital, Beijing, China Introduction: Increased augmentation index (AIx) are associated with a more rapid progression of decline of renal function in patients with chronic kidney disease (CKD). However, whether AIx could affect the future kidney outcome among patients without CKD still remains uncertain. Objectives: We aimed to investigate the impact of baseline AIx on the kidney function decline among the population without baseline CKD. Methods: A total of 3164 Chinese subjects with estimated glomerular filtration rate (eGFR) > 60ml/min/1.73 m2 from an atherosclerosis cohort were included in our analysis. Baseline AIx normalized to heart rate of 75 beats per minute (AIp75) was obtained using HEM-9000AI (Omron Healthcare Co., Ltd.). EGFR of both baseline and follow-up were calculated using CKD-EPI formula. ). Multivariate regression models were used to evaluate association of AIp75 and rapid kidney function decline defined as a drop in GFR category accompanied by a 25% or a sustained decline in eGFR of more than 5 ml/min/1.73 m2/year. Results: Subjects were 56.6 8.5 years old, 36% were male, and 49.3% had hypertension. Mean (SD) baseline AIp75 was 80.5 12.0 Mean (SD) and baseline eGFR was 101.2 10.6 ml/min/1.73 m2. After 2.3 years follow-up, the incidence of rapid decline was 7.3%. AIp75 (per each 10 increase) tended to be associated with rapid kidney function decline (OR, 95% CI, 1.13, 0.977-1.27, p¼0.056) after adjustment for demographic variables, risk factors, comorbidities and baseline eGFR. When stratified according to age, gender, diabetes, and eGFR at baseline respectively, AIp75 was an independent predictor for rapid renal function decline in subgroups of the elderly, female, diabetes and mildly impaired renal function (eGFR 60-90 ml/min/1.73 m2) (Figure 1).
Conclusion: Augmentation index might be a predictive risk factor related to early renal function decline in Chinese community-based population without chronic kidney disease, especially in elderly, female, diabetic population and patients with slightly reduction of kidney function. Disclosure of Interest: None Declared
GHEART Vol 11/2S/2016
j
June, 2016
j
POSTER/WCC_2016-POSTERS