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Quality of life, anxiety, and depression: Negative associations in college students
S54
Abstract/Journal of Affective Disorders 122 (2010) S42–S72
[P1.3.15] The association of weight gain with mood symptoms and functional outcomes following a first manic episode: Prospective 12-month data from the systematic treatment optimization program for early mania (STOP-EM) D.J. Bond, M. Kunz⁎, I.J. Torres, R.W. Lam, L.N. Yatham et al. University of British Columbia, Canada Objective: Up to 75% of patients with bipolar I disorder (BD) are overweight or obese. Obesity has been associated with poor physical health and an increased frequency of mood episodes in BD, and with impaired functioning in the general population, but the association between weight gain and functional outcomes in BD has received little attention. Methods: We measured rates of clinically significant weight gain (CSWG), defined as gaining ≥ 7% of baseline weight, over 12 months in 46 patients with BD who recently recovered from their first manic episode. We compared patients with and without CSWG for 1) the amount of time spent with mood symptoms, assessed using standard clinical rating scales and NIMH Life Charts, and 2) 12month functional outcomes, measured using the Multidimensional Scale of Independent Functioning (MSIF). Results: Forty-one percent of patients (N = 19) experienced CSWG by 12 months. CSWG was not significantly associated with the number of days with mania, hypomania, depression, or any mood symptoms during the follow-up period. Patients with CSWG had significantly poorer global functioning at 12 months than those without CSWG (MSIF score = 2.26 vs 1.74; p = 0.011). Functional impairment was independent of recent or current mood symptoms, which were entered as covariates in our analyses. Conclusions: CSWG in the 12 months following a first manic episode is associated with significantly impaired functioning in patients with BD. Weight gain should be understood as affecting not only patients’ physical health, but also their ability to truly recover from BD and to lead full, productive lives. Clinicians should consider the possibility of weight gain when making the earliest treatment decisions in BD. Keywords: Bipolar disorder; Weight gain; Overweight; Obesity; Recurrence; Psychosocial functioning doi:10.1016/j.jad.2010.02.059
[P1.3.16] Quality of life, anxiety, and depression: Negative associations in college students A. Abdel-Khalek Kuwait University, Kuwait Introduction: Quality of live (QOL) is a multicontextual concept that has been arisen from several disciplines: biology, medicine, psychology, sociology, ecology and economics. QOL involves mainly psychological components. It has become an important outcome criterion for psychological and psychiatric interventions. There is a possible assessment overlap between QOL and psychopathology.
Objective: To examine the relationship between quality of life and psychopathology, mainly anxiety and depression among college students. Methods: A sample of 224 male and female Kuwait University college students took part in the study (M age = 20.8 yr, SD = 1.5). They responded to the Arabic forms of the World Health Organization Quality of Life Scale- short form (WHOQOL-Bref), the Center for Epidemiological Studies-Depression Scale (CES-D), and the Kuwait University Anxiety Scale (KUAS).The three scales have good reliability and validity in Arabic samples. Results: Anxiety (KUAS) and depression (CES-D) were significantly and negatively associated with the QOL total score as well as its subscales: general QOL, general health, and physical, psychological, social, and environmental QOL. The correlation coefficients ranged between -.261 and -.537 (p < .01 and above, 2 -tailed). Conclusion: There is a measurement overlap between QOL and psychopathology namely, anxiety and depression. It is suggested that the QOL scales should be used in conjunction with scales of anxiety and depression. By and large, the amelioration of the negative mental state may enhance quality of life. Keywords: Quality of life; Anxiety; Depression; College students doi:10.1016/j.jad.2010.02.060
[P1.3.17] Physical activity as a treatment for depression: An outline of the TREAD study M. Chalder⁎1, A. Montgomery1, S. Hollinghurst1, D. Sharp1, J. Campbell2, G. Lewis1 1
University of Bristol, United Kingdom Peninsula Medical School, Exeter, United Kingdom
2
Objective: Whilst anti-depressants provide a clinically effective treatment for many within the primary care setting, it has been shown that patients and GPs would like to have access to alternative options, particularly for the more common, less severe forms of depression. Research to date suggests that physical activity can be beneficaial for this patient population. The TREAD study is designed, therefore, to investigate whether physical activity, in addition to usual GP care, can change clinical depression outcomes. Methods: TREAD is a pragmatic, multi-centre, randomised controlled trial with two treatment arms; phiysical activity plus usual GP care or usual GP care alone. The study's primary outcome is the Beck Depression Inventory (BDI) score measured 4-months after randomisation, with a range of other secondary outcomes measured at 4, 8 and 12 month follow-up. Qualitative work is investigating the acceptability and perceived benefits of the physical activity intervention and an economic evaluation of costs / benefits is also being conducted. Results: The study is ongoing, with a baseline sample of 361 patients consulting in general practices from the Bristol and Exeter areas of the United Kingdom. This poster provides a summary of participants' baseline characteristics and plans for data analysis with final trial results becoming avialable in early 2011. Conclusions: It is hoped that TREAD will provide a better understanding of the potential benefits of physical activity as a treatment for depression.
doi:10.1016/j.jad.2010.02.060
Abstract/Journal of Affective Disorders 122 (2010) S42–S72
[P1.3.15] The association of weight gain with mood symptoms and functional outcomes following a first manic episode: Prospective 12-month data from the systematic treatment optimization program for early mania (STOP-EM) D.J. Bond, M. Kunz⁎, I.J. Torres, R.W. Lam, L.N. Yatham et al. University of British Columbia, Canada Objective: Up to 75% of patients with bipolar I disorder (BD) are overweight or obese. Obesity has been associated with poor physical health and an increased frequency of mood episodes in BD, and with impaired functioning in the general population, but the association between weight gain and functional outcomes in BD has received little attention. Methods: We measured rates of clinically significant weight gain (CSWG), defined as gaining ≥ 7% of baseline weight, over 12 months in 46 patients with BD who recently recovered from their first manic episode. We compared patients with and without CSWG for 1) the amount of time spent with mood symptoms, assessed using standard clinical rating scales and NIMH Life Charts, and 2) 12month functional outcomes, measured using the Multidimensional Scale of Independent Functioning (MSIF). Results: Forty-one percent of patients (N = 19) experienced CSWG by 12 months. CSWG was not significantly associated with the number of days with mania, hypomania, depression, or any mood symptoms during the follow-up period. Patients with CSWG had significantly poorer global functioning at 12 months than those without CSWG (MSIF score = 2.26 vs 1.74; p = 0.011). Functional impairment was independent of recent or current mood symptoms, which were entered as covariates in our analyses. Conclusions: CSWG in the 12 months following a first manic episode is associated with significantly impaired functioning in patients with BD. Weight gain should be understood as affecting not only patients’ physical health, but also their ability to truly recover from BD and to lead full, productive lives. Clinicians should consider the possibility of weight gain when making the earliest treatment decisions in BD. Keywords: Bipolar disorder; Weight gain; Overweight; Obesity; Recurrence; Psychosocial functioning doi:10.1016/j.jad.2010.02.059
[P1.3.16] Quality of life, anxiety, and depression: Negative associations in college students A. Abdel-Khalek Kuwait University, Kuwait Introduction: Quality of live (QOL) is a multicontextual concept that has been arisen from several disciplines: biology, medicine, psychology, sociology, ecology and economics. QOL involves mainly psychological components. It has become an important outcome criterion for psychological and psychiatric interventions. There is a possible assessment overlap between QOL and psychopathology.
Objective: To examine the relationship between quality of life and psychopathology, mainly anxiety and depression among college students. Methods: A sample of 224 male and female Kuwait University college students took part in the study (M age = 20.8 yr, SD = 1.5). They responded to the Arabic forms of the World Health Organization Quality of Life Scale- short form (WHOQOL-Bref), the Center for Epidemiological Studies-Depression Scale (CES-D), and the Kuwait University Anxiety Scale (KUAS).The three scales have good reliability and validity in Arabic samples. Results: Anxiety (KUAS) and depression (CES-D) were significantly and negatively associated with the QOL total score as well as its subscales: general QOL, general health, and physical, psychological, social, and environmental QOL. The correlation coefficients ranged between -.261 and -.537 (p < .01 and above, 2 -tailed). Conclusion: There is a measurement overlap between QOL and psychopathology namely, anxiety and depression. It is suggested that the QOL scales should be used in conjunction with scales of anxiety and depression. By and large, the amelioration of the negative mental state may enhance quality of life. Keywords: Quality of life; Anxiety; Depression; College students doi:10.1016/j.jad.2010.02.060
[P1.3.17] Physical activity as a treatment for depression: An outline of the TREAD study M. Chalder⁎1, A. Montgomery1, S. Hollinghurst1, D. Sharp1, J. Campbell2, G. Lewis1 1
University of Bristol, United Kingdom Peninsula Medical School, Exeter, United Kingdom
2
Objective: Whilst anti-depressants provide a clinically effective treatment for many within the primary care setting, it has been shown that patients and GPs would like to have access to alternative options, particularly for the more common, less severe forms of depression. Research to date suggests that physical activity can be beneficaial for this patient population. The TREAD study is designed, therefore, to investigate whether physical activity, in addition to usual GP care, can change clinical depression outcomes. Methods: TREAD is a pragmatic, multi-centre, randomised controlled trial with two treatment arms; phiysical activity plus usual GP care or usual GP care alone. The study's primary outcome is the Beck Depression Inventory (BDI) score measured 4-months after randomisation, with a range of other secondary outcomes measured at 4, 8 and 12 month follow-up. Qualitative work is investigating the acceptability and perceived benefits of the physical activity intervention and an economic evaluation of costs / benefits is also being conducted. Results: The study is ongoing, with a baseline sample of 361 patients consulting in general practices from the Bristol and Exeter areas of the United Kingdom. This poster provides a summary of participants' baseline characteristics and plans for data analysis with final trial results becoming avialable in early 2011. Conclusions: It is hoped that TREAD will provide a better understanding of the potential benefits of physical activity as a treatment for depression.
doi:10.1016/j.jad.2010.02.060