Radical radiation treatment of operable (stage I and II) breast cancer following limited surgery

Radical radiation treatment of operable (stage I and II) breast cancer following limited surgery

ficult group to diagnose by mammography alone; whereas, all 16 patients were correctly diagnosed by aspiration cytology. The value of aspiration cytol...

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ficult group to diagnose by mammography alone; whereas, all 16 patients were correctly diagnosed by aspiration cytology. The value of aspiration cytology as a cellular technique for diagnosing and following the patient with dysplastic breasts is strongly recommended.

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RADICALRADIATIONTREATMENT OF OPERABLE (STAGE I AND II) BREAST CANCER FOLLOWING LIMITED SURGERY A. M. Chu, M.D.*; 0. Cope, M.D.; R. Russo, B.S., and K. Rothman, D.P.H. Department of Radiation Medicine Massachusetts General Hospital Boston, Massachusetts

140 patients with surgically operable Tl-2, No-l invasive breast carcinoma were treated with limited surgical incision or excision followed by a course of radical radiotherapy at Massachusetts General Hospital between January 1956 through December, 1978. A 5 year survival of 80% and 5 year disease-free survival of approximately 70% was obtained. Since this series spans several years, an analysis of the patterns of recurrence, type of surgery, e.g., incision versus excision and dose response relationship with residual tumor will be analyzed. A discussion of effect of various equipment and treatment techniques used on Tocal control will be discussed. A multifactorial analysis using various parameters of histological examination, e.g., blood vessel invasion, lymphatic vessel, perineural invasion, et cetera, will be analyzed. The impact of adjuvant chemotherapy on survival of these patients will be presented. Complications and cosmesis as a function of treatment given will be presented.

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COMBINATION OF EXTERNAL AND INTERSTITIAL IRRADIATION IN THE PRIMARY MANAGEMENT OF BREAST CARCINOMA A.M. Nisar Syed, M.D.*; F.W. George III, M.D.; J. Thropay, M.D.; and J. Lipsett, M.D. University of Southern California School of Medicine Division of Radiation Medicine Los Angeles, California A. Puthawala, California Southern Los

M.D., and P. Fleming, M.D. Hospital Medical Center/ California Cancer Center Angeles, California

For several decades irradiation has been used effectively in the primary management of carcinoma of the breast. We have treated 83 patients with carcinoma of the breast using a combination of external and interstitial irradiation at Los Angeles County-University of Southern California Medical Center and Southern Califonria Cancer Center from All 30 patients who had Tl February 1, 1975 until December 31, 1977.

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