Radiobiology in clinical radiation therapy—Part IV: Radiobiology normal tissue pathology

Radiobiology in clinical radiation therapy—Part IV: Radiobiology normal tissue pathology

Proceedings of the 40th Annual ASTRO Meeting l 15 REFRESHER COURSE DESCRIPTIONS Conclusions: Long-term results suggest that with careful follow-up, ...

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Proceedings of the 40th Annual ASTRO Meeting

l 15

REFRESHER COURSE DESCRIPTIONS Conclusions: Long-term results suggest that with careful follow-up, breast cancer specific survival equivalent with mastectomy can be achieved in selected cases of DCIS treated with breast conserving surgery and radiation. Further follow-up will be required to define whether a subset of these patients, likely based on size, grade, margins, and perhaps cytogenetic prognostic factors, exists for whom the radiation may safely be omitted. 410 Diagnostic Imaging in Oncology: New Challenges and Changing Strategies Ronald A. Castellino, M.D and Lawrence H. Schwartz, M.D., Memorial Sloan Kettering Cancer Center, New York, NY Diagnostic radiology and nuclear medicine studies, both imaging and therapeutic, play important roles in screening, staging, monitoring of treatment, and in long term surveillance of oncologic patients. Frequently, information from these studies, as well as from ancillary data (such as the clinical examination and laboratory studies) overlap, and it is sometimes unclear which tests and examinations to perform. Current changes in the delivery and funding of health care are prompting all specialties to evaluate their patterns of care. 411 Morbidity Associated With Radiation Therapy for Head and Neck Cancer: Measurement Tools and Prevention Strategies W. Robert Lee, M.D., Wake Forest University School of Medicine, Winston-Salem, NC Pamela Sandow, D.M.D. and Giselle J. Moore, A.R.N.P., M.S.N., A.O.C.N. University of Florida College of Medicine and Dentistry, Gainesville, FL Purpose/Objective: This course will focus on the expected morbidity associated with the delivery of high dose radiation therapy to the head and neck region. A multidisciplinary approach will be emphasized and the following topics will be addressed: 1) Appropriate dental evaluation prior to the institution of treatment, oral care during radiotherapy and management of dental complications following the completion of treatment. 2) Review of the available quality of life measures used in men including discussion of the domains used in quality of life measures. 3) Strategies to prevent acute and late morbidity including modification of conventional treatment

techniques and a review of potential radioprotective agents. 412C Radiobiology in Clinical Radiation Therapy - Part IV: Radiobiology Normal Tissue Pathology Luis Fajardo, M.D., VA Medical Center, Pa/o Alto, CA

No description available 413 Interactions of Radiation with Novel Chemotherapeutic Agents: Taxanes and Nucleoside Analogs Luka Milas, M.D., Ph.D., M.D. Anderson Hospital & Tumor Institute, Houston, TX Purpose/Objective: The objective of this course is to overview the rationale for using these drugs as radioenhancing agents, the experimental findings in preclinical studies, the mechanisms of their interaction, and the clinical application of these agents. 414C Stereotactic Radiosurgery - Part Ih Clinical Experience and Future Directions Jay S. Loeffler, M.D., Massachusetts General Hospital Boston, MA John C. Flickinger, M.D., Presbyterian University Hospital Pittsburgh, PA Hanne M. Kooy, Ph.D., Harvard Medical School Boston, MA Purpose/Objective: To review the various indications for stereotactic radiosurgery and the resulting treatment outcomes (results and complications). 415 Breast Conserving Therapy for Early Stage Invasive Cancer Barbara L. Fowble, M.D., Fox Chase Cancer Center, Philadelphia, PA Purpose/Objective: To discuss clinical, pathologic, and treatment related issues in the management of early stage invasive breast cancer through case presentations with an emphasis on evidence-based medicine.