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Re: Perirenal Hematoma after Ureteroscopy: A Systematic Review
UROLITHIASIS/ENDOUROLOGY
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TRPV-5 activity but this did not occur with mutant MUC1. Enhancing MUC1 activity may be a future treatment approach for patients with calcium kidney stones. Dean G. Assimos, MD
Suggested Reading Pearle MS, Goldfarb DS, Assimos DG et al: Medical management of kidney stones: AUA guideline. J Urol 2014; 192: 316. Dinour D, Beckerman P, Ganon L et al: Loss-of-function mutations of CYP24A1, the vitamin D 24-hydroxylase gene, cause long-standing hypercalciuric nephrolithiasis and nephrocalcinosis. J Urol 2013; 190: 552.
Re: Perirenal Hematoma after Ureteroscopy: A Systematic Review L. A. Whitehurst and B. K. Somani Departments of Urology, Royal Hampshire County Hospital, Winchester and University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom J Endourol 2017; Epub ahead of print. doi: 10.1089/end.2016.0832
Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/28001097 Editorial Comment: The authors performed a meta-analysis of the occurrence of perirenal hematoma after ureteroscopy. The risk was 0.45%. The majority of these patients had symptoms or signs suggesting possible hemorrhage. Risk factors included severe hydronephrosis, cortical thinning, hypertension, recent urinary tract infection and long operative time. The majority of these cases can be managed conservatively. This occurrence can be limited with careful manipulation of ureteroscopes, guidewires and other instruments, and measures to reduce intrarenal pressure, such as use of an access sheath and avoidance of high pressure irrigation. Dean G. Assimos, MD
Suggested Reading Pais VM Jr, Smith RE, Stedina EA et al: Does omission of ureteral stents increase risk of unplanned return visit? A systematic review and meta-analysis. J Urol 2016; 196: 1458. Bloom J, Matthews G and Phillips J: Factors influencing readmission after elective ureteroscopy. J Urol 2016; 195: 1487. Skolarikos A, Gross AJ, Krebs A et al: Outcomes of flexible ureterorenoscopy for solitary renal stones in the CROES URS global study. J Urol 2015; 194: 137.
Re: Outcomes of Percutaneous Nephrolithotomy in Spinal Cord Injury Patients as Compared to a Matched Cohort K. G. Baldea, R. H. Blackwell, S. Vedachalam, A. N. Kothari, P. C. Kuo, G. N. Gupta and T. M. Turk Department of Urology, One:MAP Division of Clinical Informatics and Analytics, and Department of Surgery, Loyola University Chicago, Maywood, Illinois Urolithiasis 2016; Epub ahead of print. doi: 10.1007/s00240-016-0958-6
Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/27999875 Editorial Comment: These investigators queried an inpatient database to analyze outcomes of patients undergoing percutaneous nephrolithotomy in California and Florida from 2007 to 2011. They compared the results of patients with spinal cord injury to those without this comorbidity. They used propensity score matching to adjust for other comorbidities. The spinal cord injury group had significantly longer lengths of stay and more complications, including pneumonia and sepsis. Inpatient mortality rates approached statistical significance, at 3.1% vs 4.2% for patients with spinal cord injury. These patients and those with spina bifida require careful preoperative preparation and perioperative care to limit such occurrences. Despite these measures, these events still occur. This cohort needs to be informed that they are at increased risk for such complications. Dean G. Assimos, MD
Dochead: Urological Survey
LIT 5.4.0 DTD JURO14684_proof 11 April 2017 1:36 am EO:
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115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171
TRPV-5 activity but this did not occur with mutant MUC1. Enhancing MUC1 activity may be a future treatment approach for patients with calcium kidney stones. Dean G. Assimos, MD
Suggested Reading Pearle MS, Goldfarb DS, Assimos DG et al: Medical management of kidney stones: AUA guideline. J Urol 2014; 192: 316. Dinour D, Beckerman P, Ganon L et al: Loss-of-function mutations of CYP24A1, the vitamin D 24-hydroxylase gene, cause long-standing hypercalciuric nephrolithiasis and nephrocalcinosis. J Urol 2013; 190: 552.
Re: Perirenal Hematoma after Ureteroscopy: A Systematic Review L. A. Whitehurst and B. K. Somani Departments of Urology, Royal Hampshire County Hospital, Winchester and University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom J Endourol 2017; Epub ahead of print. doi: 10.1089/end.2016.0832
Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/28001097 Editorial Comment: The authors performed a meta-analysis of the occurrence of perirenal hematoma after ureteroscopy. The risk was 0.45%. The majority of these patients had symptoms or signs suggesting possible hemorrhage. Risk factors included severe hydronephrosis, cortical thinning, hypertension, recent urinary tract infection and long operative time. The majority of these cases can be managed conservatively. This occurrence can be limited with careful manipulation of ureteroscopes, guidewires and other instruments, and measures to reduce intrarenal pressure, such as use of an access sheath and avoidance of high pressure irrigation. Dean G. Assimos, MD
Suggested Reading Pais VM Jr, Smith RE, Stedina EA et al: Does omission of ureteral stents increase risk of unplanned return visit? A systematic review and meta-analysis. J Urol 2016; 196: 1458. Bloom J, Matthews G and Phillips J: Factors influencing readmission after elective ureteroscopy. J Urol 2016; 195: 1487. Skolarikos A, Gross AJ, Krebs A et al: Outcomes of flexible ureterorenoscopy for solitary renal stones in the CROES URS global study. J Urol 2015; 194: 137.
Re: Outcomes of Percutaneous Nephrolithotomy in Spinal Cord Injury Patients as Compared to a Matched Cohort K. G. Baldea, R. H. Blackwell, S. Vedachalam, A. N. Kothari, P. C. Kuo, G. N. Gupta and T. M. Turk Department of Urology, One:MAP Division of Clinical Informatics and Analytics, and Department of Surgery, Loyola University Chicago, Maywood, Illinois Urolithiasis 2016; Epub ahead of print. doi: 10.1007/s00240-016-0958-6
Abstract available at http://www.ncbi.nlm.nih.gov/pubmed/27999875 Editorial Comment: These investigators queried an inpatient database to analyze outcomes of patients undergoing percutaneous nephrolithotomy in California and Florida from 2007 to 2011. They compared the results of patients with spinal cord injury to those without this comorbidity. They used propensity score matching to adjust for other comorbidities. The spinal cord injury group had significantly longer lengths of stay and more complications, including pneumonia and sepsis. Inpatient mortality rates approached statistical significance, at 3.1% vs 4.2% for patients with spinal cord injury. These patients and those with spina bifida require careful preoperative preparation and perioperative care to limit such occurrences. Despite these measures, these events still occur. This cohort needs to be informed that they are at increased risk for such complications. Dean G. Assimos, MD
Dochead: Urological Survey
LIT 5.4.0 DTD JURO14684_proof 11 April 2017 1:36 am EO:
172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228