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Relation of nutritional deficiency to cardiac dysfunction
Lewis,
T.:
Congenital
Tricuspid
Stenosis.
Clin.
SC. 5: 261,
19G.
A ~‘a30 of tricuspid steno3is in a newly born child is described. The macroscopic alJpearance was that of endocarditis, but on histologic examination it was found that the lwion was a ~~ongenital malformation. Valvular deformities discovered in early life are belicw~d 11, lw 11sua1ly if not always the result of aongenita.1 malformation rather than endoTi Ar1,4(‘E. 1’3 rditis.
Pickering,
G. W., and Sanderson,
P. H.:
Angina
Pectoris
and Tobacco.
(Yin. Sr. 5: 27.;.
‘l‘~~lnt~~.rJ angina is regarded 11)~ the authors a< rare in owurrence but important IK~‘3ir.w elf’ its implications that tobacco may cause constriction of the coronary arteries. Three I’:I,-CR are reported in which angina1 pain was induced or aggravated by smoking. One of the patients was ~~arefully studied with respect to the manner in which smoking produced the pain. Khrn the patient, smoked following the disappearance of pain produced by esercipe, the pain rc:t ppeare~l. It reappeared, howrvcr, only if smoking was awompanied by an adequate in~‘rease in pulse rate. Exercise tnlerance wxs not reduced by smoking before or during the eserciw. Smoking was therefore a relatively minor factor in the production of angina1 pain in this case, and it appeared to produce the pain by increasing the work of the heart rather than by causing vnsoconstriction. Tt is pointed out that use of the term “tobacco .s;rnoking [tl:rys such a relatively small and in-onwquential pain.
angina ” is scarcely justifiable since part in the production of angina1 LaPLact.
Eyster, J. A. E., and Gilson, W. E.: The Development Potential. Am. .T. I’hysiol. 145: 507 (Feb.) 19.M.
and Contour
of Cardiac
Injury
By applying increasing increments of suction to a small region of heart muscle, the Ilevelopment of injury potentials of rest and activity has been observed. When completely developed! the injury potential curve of activity is fundamentally monophasic in form and consists of only two parts: (I) a part in a-hieh the resting potential, negative with respect to uninjured resting muscle, is rapidly abolished and replaced by a potential positive n-ith respect to the same reference, and (2) a slower and continued decline of the lJotentia1 to the resting state. Modifications in this curve causing it to depart from this strictly monophasic type may result from two factors, inclusion of action potentials from uninjured regions of the muecle and from incomplete or nonuniform injury. The former occur most prominently in bipolar leads, arr leas often present in unipolar leads, and are usually absent in coaxial leads. The latter effevtv are prominent during the development of suction injuries or during their sub3idence and are alway3, in our experience, present. in in jury potential curves derived from burned or crushed regions. _. Tt is shown by several experimental methods that the injury potential of activity i> derived solely from the region of injury or the immediately contiguous tissue. The electrode cJn unin,jured tissue contributes to the recortled curve only by the adqlition of active potential components arising from the region IIf the electrode or from ncumnl heart tissue intervening between 1hca two electrodes. A,TRORS.
Wintrobe, JIe(l.
M. M.: 76:
Relation
341 (Nov.-Dee.)
of Nutritional
Deficiency
to Cardiac
Dysfunction.
Arch. ht.
191.5.
Tl1i.s article contains a good summary of the cardiac effect3 of nutritional deficiency. The author reviews the literature on the subject from the clinical and experimental standpoints and reports his own experiments upon the production of thiamine deficiency in pigs. The effects of aritaminoses, particularly of vitamin B,, are tliwus3ed from the clinical, electro121rrliogrnpll ic, and pathologic standpoints. BELLET.
T.:
Congenital
Tricuspid
Stenosis.
Clin.
SC. 5: 261,
19G.
A ~‘a30 of tricuspid steno3is in a newly born child is described. The macroscopic alJpearance was that of endocarditis, but on histologic examination it was found that the lwion was a ~~ongenital malformation. Valvular deformities discovered in early life are belicw~d 11, lw 11sua1ly if not always the result of aongenita.1 malformation rather than endoTi Ar1,4(‘E. 1’3 rditis.
Pickering,
G. W., and Sanderson,
P. H.:
Angina
Pectoris
and Tobacco.
(Yin. Sr. 5: 27.;.
‘l‘~~lnt~~.rJ angina is regarded 11)~ the authors a< rare in owurrence but important IK~‘3ir.w elf’ its implications that tobacco may cause constriction of the coronary arteries. Three I’:I,-CR are reported in which angina1 pain was induced or aggravated by smoking. One of the patients was ~~arefully studied with respect to the manner in which smoking produced the pain. Khrn the patient, smoked following the disappearance of pain produced by esercipe, the pain rc:t ppeare~l. It reappeared, howrvcr, only if smoking was awompanied by an adequate in~‘rease in pulse rate. Exercise tnlerance wxs not reduced by smoking before or during the eserciw. Smoking was therefore a relatively minor factor in the production of angina1 pain in this case, and it appeared to produce the pain by increasing the work of the heart rather than by causing vnsoconstriction. Tt is pointed out that use of the term “tobacco .s;rnoking [tl:rys such a relatively small and in-onwquential pain.
angina ” is scarcely justifiable since part in the production of angina1 LaPLact.
Eyster, J. A. E., and Gilson, W. E.: The Development Potential. Am. .T. I’hysiol. 145: 507 (Feb.) 19.M.
and Contour
of Cardiac
Injury
By applying increasing increments of suction to a small region of heart muscle, the Ilevelopment of injury potentials of rest and activity has been observed. When completely developed! the injury potential curve of activity is fundamentally monophasic in form and consists of only two parts: (I) a part in a-hieh the resting potential, negative with respect to uninjured resting muscle, is rapidly abolished and replaced by a potential positive n-ith respect to the same reference, and (2) a slower and continued decline of the lJotentia1 to the resting state. Modifications in this curve causing it to depart from this strictly monophasic type may result from two factors, inclusion of action potentials from uninjured regions of the muecle and from incomplete or nonuniform injury. The former occur most prominently in bipolar leads, arr leas often present in unipolar leads, and are usually absent in coaxial leads. The latter effevtv are prominent during the development of suction injuries or during their sub3idence and are alway3, in our experience, present. in in jury potential curves derived from burned or crushed regions. _. Tt is shown by several experimental methods that the injury potential of activity i> derived solely from the region of injury or the immediately contiguous tissue. The electrode cJn unin,jured tissue contributes to the recortled curve only by the adqlition of active potential components arising from the region IIf the electrode or from ncumnl heart tissue intervening between 1hca two electrodes. A,TRORS.
Wintrobe, JIe(l.
M. M.: 76:
Relation
341 (Nov.-Dee.)
of Nutritional
Deficiency
to Cardiac
Dysfunction.
Arch. ht.
191.5.
Tl1i.s article contains a good summary of the cardiac effect3 of nutritional deficiency. The author reviews the literature on the subject from the clinical and experimental standpoints and reports his own experiments upon the production of thiamine deficiency in pigs. The effects of aritaminoses, particularly of vitamin B,, are tliwus3ed from the clinical, electro121rrliogrnpll ic, and pathologic standpoints. BELLET.