RESPIRATORY CARE PHARMACOLOGY

RESPIRATORY CARE PHARMACOLOGY

-------t j~. the bookshelf PHYSIOLOGY AND PATHOPHYSIOLOGY. Edited by E. K..: NNt7f11 WEIR and JOliN T. R..:fo:v..:s. New York: Marcel Dekker, 1989,...

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PHYSIOLOGY AND PATHOPHYSIOLOGY. Edited by E. K..: NNt7f11 WEIR and JOliN T. R..:fo:v..:s. New York: Marcel Dekker, 1989, 762 PI', $125.00

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The uppeal of this volume lies in its breadth of <..'()vera~e. The hook is divided into two parts. PO.ut one (physiolo~y) first describes phylo~enetic aspt.~cts of lung dn.'. ulation hefore turning to physical characteristk's, autonomic nu'chanisms, fetal and n(~onataJ charactt.>ristics, hypoxic and hYIX~n)xic reac,tivity, and responses to exercise, pregnan(.·y, diving and high altitude. One chapter is devoted to riJ(ht ventri('ular function in pulmonary hypertension. This is hroader covera~e than has heen provided in other volumes on lun~ circulation ancl the weater hreaclth is clearly heneficial. Part two (more patho~enesis than pathophysiol~) covers persistent hypertension in the newborn, humoral mediators in response to emholi. effects of chronk hi~h and low flow states. ~enesis of primary pulmonary hypertension. acute lun~ injUry, l>()ntrol of cell proliferation, and the roles of endothelium. smooth muscle cells and leukocytes in patho~enesis. Devotion of a major portion of this hook to the rclpidly growing area of lung cell biology is a strong plus, although the amount of speculation sometimes encroaches on a level previously reserved for economists. Forty-one authors, well-recognized as experien<..'ed in their topics, have contributed a total 18 chapters. Individual \\-Titing styles differ, however, such that chapters vary from sketchy summaries to tutorial essays to heavily referenced reviews. Hence, not all chapters serve all readers similarly. The ~reat majority are well organized, clearly \\-Titten, and suitahly illustrated and referene--ed. There is only a small amount of overlap (of hoth (.'tmtcnt and authors) with other ree--ent volumes on the lung interested in the pulmonary circulation will find <'irculation. Investi~at{)rs this hook a valuahle acquisition. Clinical pulmonolo~ists will want to rememher it as a useful referen<..-e that warrants examination. 111Oma,~

c.

lloyd Jr:. ~f.D. Indianapolis

PEDIATRIC CARDIOLOGY, ITS CURRENT PRACTICE. By J. TIMOTHY BRICKER and DAN G. McNAMAR.". London: Edward Arnold. 1988, 178 pp. $49.50 (US) This small, Pediatric Cardiolol!.Y, Its CUm?nt Practice hy Bricker and McNamara, represents a brief and concise presentation of a variety of current or new areas in the practice of pediatric cardiology. Obviously, the text is not intended to represent a complete review of the subject but selects a variety of topics for presentation. They include (of note): echocardiography, Doppler echocardiography, dysrhythmias, therapeutic catheterizations and surgical management. Tnle to its course, thc text basically deals with a variety of current aspt-'<.·ts of pediatric cardiology practice. Each st,-ction providcs a vcry hrief discussion of the topic. The organization is hasi<... ally quite acceptable with the ex('Cption of the separation of Doppler cchocardiography frum twodimensional echocardi{)~phy which. practically speaking. should he (.'()flsidt~red to~ether. Ohviously. the experience presented represents the comhined views of a variety of excellent clinicians from the Texas Childrens Hospital and Baylor Cone~e of Medicine. If the hook is somewhat remiss, it is only in that its references are limited hasically to those from Texas Childrens Hospital and does not provide reference material from other institutions. It certainly represents an interesting review of current practice.

S. H af!,ler. M. D. Rochester, Minnesota

Donald

THE PRACTICE OF CARDIOLOGY. 2nd ed. Edited by K. A. EAGL":, E. HABER, R. W D..:SANCTIS and W G. Al'~"F.N. Boston: Little Brown and Company, 1989, 1790 pp (2 volumes). $120.00 An almost inevitahle question <..'omes up when one picks up this ne\\~ nearly 2.000-page text on heart disease from the Massachusetts General Hospital: do we really need yet another tome in this field - when we already have Braunwald's Heart Disease, Hurst's The Heart (with all its "updates"), BrandenbuJ1('s Cardiology, and even the huge, enldite six-volume contribution by the American Physiological Society on The CardWvascular System? The answer to this question is clearly not simple. hut the present MGH product is mostly an insightful and well-written record which warrants a vote in its favor. This reviewer especially likes the succinct yet discerning introductions to many cardiovascular diseases, In certain chapters. however, more rigorous definitions should he used: it is remiss, for instance, that in

chapter 34 (dealin~ with the sequelae of pulmonary hypt.>rtensinn), tht' \\(lrld Health Or~anization's definition for chronic ('or pulmonalt> is totally omittt,d (even though it is a standard reference). Othernise. this Chapter is niedy delineated; one is especially pleased to see tht·rein a much nt>t'ded can>at that lung scans shOWing multiple area~ of \'cntilation-Ix>rfusinn mismatch can qUill- frequently he false-positive for the prcscn{'(.> of pulmonary emholization. and that pulmonary angiognlphy should, thercf()re, ht' dont' in all pati.>nts requirin~ a definitive diagnosis of pulmonary throlJlhol'lIIholism, Of (.''Onsidt·rable l ..o ncern to this rc"ieWl'r wus thl' paucity of Il'urned dis('ussion on right ventricular performance in none-'(mgl'nital udult l·urdial.· disease. and an almost total ahsen(.'e of (.'ollontrk-ular intt·radions. Thus, in the Chapter on pericardial diseast>s - whf>rc sUl'h inh>radions an' (1'Iitt· prominent-only a cursory statement or two are clpntricle: the implit·d (>ostllialt> that ri~ht ventriculo~raphy is no lon~er IWt>(le(1 or pt~rformf'rfidal discussion to the right ventricle when it (.'omes to myocardial pC'rfusion and Viability, and almost ignores this chamber completely \\,11{'n tht> aSSf'SSmt'nt of cardiac function is surveyed. Perhaps these (.'ommt..>nts at It>ast partially reflect my bias toward the ri~ht ventricle: when an or~an ht><.'omes sonwhc ldly. tht.' intent of tht, hook is to survey the cardiovascular information of immt>diat(' liSt' to a clini('al canliolo~st. Yet. to dismiss the extremely pr()misin~ (and often dink-ally aln-ady with just a sin~l(' very useful) technique of positron emission tomo~raphy paragraph in a handlxx)k containing almost 2.000 pa~t>s dt>tmds f!rt>atly from a potentially valuable dia~ostic tool. (A number of hospitals in this ('ountryincluding our O\\11-are already using positron emission tomo~raphy and the appropriate coronary flow plus myoc:ardial metalx)lism radiolahds such as '"IN-ammonia and '''F-ftuoro-2-deoxyglu<..'ose to detennine in l'ritil'ally ill hut operatively very borderline <..'onmary caSlas who is to unde~() opt'n heart hypass surgery and who is not.) Despite some of these short<..'()mings, I found l1,e Practice uf Cardiology a pleasure to read. It brims with carefully inte~.lted canons for most (.·ardiova.~('ular disease pox-esscs in most instancl's; in I(l'lwml it is also ",rittt'n in a manner that makes it prohahly the (~asiest of ~'ardio"as(.'ular hanclhooks to read among all the aforementioned contrihutions. As sm,'h it. tlwrt·fc)rl·. helongs to the trove of many a lihrary; I think that it \\;11 1)(' partkularly useful to the cardiova.~ular fellows-in-tr.linin~ and tht· ~ellt'ral inh'rnist~ who concentrate primarily on the ('ardiova.«·ular disordt>rs.

jack Ferlira:. ~I.J) .. FC.C.P. Sout hfieltl, .\1it'll il!ll1l RESPIRATORY CARE PHARMACOLOGY. 3rd ed. By Jos ..:.... L. Ru'. Chica~o: Year Book Medical Publishers Inc. 1989,360 pp. $27.95

In.

As stated in the preface, the purpose of the hook is "to provid{> a dt'ar and introduction to the dru~s used in rt'spimtory carl''', It is urganizt.'d and written in a manner which Ininhnizt's assumptiuns rq,~a . . din~ the readers background knowledge. It introduces respiratory nws. It also provides information about other dnlgs relevant (hut not always directly) to the care of patients with respiratory illness. This indmlt's antibiotics. narcotics. cardiovascular agents. diuretks. and st.'datives. This book is written for respiratory therapists and healthcare provi(lers attending to patients with lung diseases. It is an introductory treatist· on dnlgs associated with respiratory care. As stich, it is not "Titten for physicians. It reads well and has numerous simple line drawings which adt'qllatdy illustrate points that the author desires to make. As a paperha<.,'k, it carries an affordable price. It provides. in my opinion. a very reasonahle first slt-p in learning about the pharmac(}lo~ of respiratory can>. well-()r~anized

Daniel

f~.

Banks, .\f. J).

Morf!,antown. \Vest Virl!inia

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