Book Review ~esioratiue N~rolo~, Vol. 3 (Clinical N~arop~~sia~a~ in Peripheral N~urapath~~s~, edited by P.J. Delwaide and A. Gorio, Elsevier, Amsterdam, 1985, 174 pp., U.S. $80.00. The contributors to this short volume concerned with restorative neurology met in Venice in 1983. The theme of this symposium and of the book is regeneration in the human peripheral nervous system after nerve injury. The book starts with a few chapters mainly dealing with peripheral nerve regeneration following experimental lesions in animals. Both anatomical and physiological data concerning the characteristics of various regenerating neuronal structures are presented. There follow chapters describing new approaches to investigate and restore peripheral nerve fibre functions in man. The second half of the book deals with routine techniques currently used in clinical neurophysiology to evaluate the extent of regeneration and aid in the prognosis of return of function after repair of nerve lesions in man. Included in these chapters are also aspects on the values and limitations of the techniques in use as well as some speculations concerning future developments in this field. A large gap which was not covered by the symposium and, consequently, not covered by this book, is that much rather new and highly important data on the central effects of peripheral nerve injury were omitted. There is now considerable evidence that deficits in function after nerve injury and repair are not only due to inadequate regeneration but to irreversible changes at all levels of the CNS. The clinical implications of these experimental observations need to be considered and, thus, the fact that the book deals exclusively with peripheral function limits its value. As in other publications of this type the different chapters vary considerably both in length and quality. A few of the longer chapters would have benefitted by being cut down. Some presentations lack concluding paragraphs which often can be helpful to the reader. The layout and printing is very good. For its contents the volume is rather expensive. Keeping its limitations in mind, the book may be of interest for medical and scientific professionals with an interest in restorative neurology.
R.G. Hallin department of Clinical Ne~raph~s~a~a~, Huddinge University Hospital, I41 86 Huddinge (Sweden) 0304-3959/87/$03.50 0 1987 ElsevierSciencePublishersB.V. (Biomedical Division)