Retrograde Deep Femoral Artery Access as Bailout Technique to Rescue Unexpected Ostial Occlusion during Antegrade Superficial Femoral Artery Recanalization

Retrograde Deep Femoral Artery Access as Bailout Technique to Rescue Unexpected Ostial Occlusion during Antegrade Superficial Femoral Artery Recanalization

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Journal Pre-proof Retrograde deep femoral artery access as bailout technique to rescue unexpected ostial occlusion during antegrade superficial femoral artery recanalization. Gabriele Testi, MD, PhD, Tanja Ceccacci, MD, PhD, Elisa Paciaroni, MD, Fabio Tarantino, MD, Giorgio Ubaldo Turicchia, MD PII:

S0890-5096(20)30018-2

DOI:

https://doi.org/10.1016/j.avsg.2019.12.041

Reference:

AVSG 4853

To appear in:

Annals of Vascular Surgery

Received Date: 15 November 2019 Revised Date:

15 December 2019

Accepted Date: 17 December 2019

Please cite this article as: Testi G, Ceccacci T, Paciaroni E, Tarantino F, Turicchia GU, Retrograde deep femoral artery access as bailout technique to rescue unexpected ostial occlusion during antegrade superficial femoral artery recanalization., Annals of Vascular Surgery (2020), doi: https://doi.org/10.1016/ j.avsg.2019.12.041. This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain. © 2020 Published by Elsevier Inc.

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Retrograde deep femoral artery access as bailout technique to rescue unexpected ostial

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occlusion during antegrade superficial femoral artery recanalization.

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Authors:

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1) Gabriele Testi, MD, PhD

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Cardiovascular Department, Forlì-Cesena Vascular Surgery Unit, Morgagni-Pierantoni

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Hospital, Azienda USL della Romagna, Forlì (FC), Italy

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[email protected]

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2) Tanja Ceccacci, MD, PhD,

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Cardiovascular Department, AUSL Romagna, Forlì-Cesena Vascular Surgery Unit, Morgagni-

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Pierantoni Hospital, Forlì (FC), Italy

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[email protected]

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3) Elisa Paciaroni, MD,

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Cardiovascular Department, AUSL Romagna, Forlì-Cesena Vascular Surgery Unit, Morgagni-

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Pierantoni Hospital, Forlì (FC), Italy

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[email protected]

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4) Fabio Tarantino, MD,

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Cardiovascular Department, AUSL Romagna, Interventional Cardiology, Morgagni-Pierantoni

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Hospital, Forlì (FC), Italy

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[email protected]

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5) Giorgio Ubaldo Turicchia, MD,

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Cardiovascular Department, AUSL Romagna, Forlì-Cesena Vascular Surgery Unit, Morgagni-

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Pierantoni Hospital, Forlì (FC), Italy

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[email protected] 1

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Total word count: 1038

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Declaration of Conflicting Interests

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The authors declared no potential conflicts of interest with respect to the research, authorship,

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and/or publication of this article.

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Funding

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The authors received no financial support for the research, authorship, and/or publication of

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this article.

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Corresponding Author:

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Gabriele Testi, Cardiovascular Department, AUSL Romagna, Forlì-Cesena Vascular Surgery

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Unit, Morgagni-Pierantoni Hospital, Via C. Forlanini 34, 47121 Forlì (FC), Italy

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Email: [email protected]

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ABSTRACT

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We report a case of deep femoral artery (DFA) retrograde access for recanalization of an

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accidental ostial occlusion complicating an antegrade-retrograde superficial femoral artery

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(SFA) procedure. A 77-year-old man with chronic limb-threatening ischemia of the right lower

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limb was submitted to a duplex ultrasound which showed a heavy calcified SFA chronic total

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occlusion. During antegrade and retrograde attempts to cross the SFA obstruction, a control

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angiogram unexpectedly showed the ostial occlusion of DFA. Several antegrade attempts to

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cross the DFA occlusion with various guidewires and catheters were unsuccessfully made.

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Retrograde access was achieved by direct puncture of the DFA distally to the first perforating

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artery. With sheathless approach the occlusion was crossed, the retrograde guidewire was

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externalized through the femoral sheath, and the balloon angioplasty was than antegradely

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performed. The SFA recanalization was interrupted because of patient discomfort. The patient

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had an uncomplicated recovery, with immediate resolution of rest pain probably due to the

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resolution of the underestimated DFA stenosis. The retrograde DFA access is a useful bailout

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technique in case of accidental ostial occlusion of DFA.

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Introduction

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Even if the surgical approach is considered the first choice in the treatment of long

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femoropopliteal occlusive disease, endovascular treatment is widely recognized as an option

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in high-risk patients with chronic limb-threatening ischemia (CLTI). Thanks to the recent

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technical improvements, even complex lesions such as flush ostial occlusion of the superficial

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femoral artery (SFA) has been treated with the endovascular techniques. These lesions are a

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frequent cause of failure of endovascular treatment precluding engagement of SFA.1 When

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the atherosclerotic process involves the proximal SFA, also the deep femoral artery (DFA) is

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frequently affected.2 In many cases, the DFA presents focal disease localized in its origin and

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the proximal portion.2,3 For this reason, management of guidewires and catheters at the SFA

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origin can compromise the DFA ostium. We report a case of DFA retrograde access as a

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bailout technique to rescue an accidental occlusion of DFA.

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Case Report

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A 77-year-old man presented to our attention with CLTI of the right lower limb with untreatable

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rest pain (Rutherford Class 4). The patient was submitted one year before to a left femoro-

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peroneal in-situ saphenous vein bypass grafting. The medical history included hypertension,

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dyslipidemia, kidney transplantation after bilateral nephrectomy, severe aortic valve stenosis,

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and recent percutaneous endoscopic gastrostomy for aspiration pneumonia.

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The preprocedural duplex ultrasound showed an SFA chronic total occlusion with extreme

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parietal calcifications of all lower limb vessels. Antegrade ipsilateral common femoral artery

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(CFA) access was gained, and a 5F sheath was inserted. The diagnostic angiogram

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confirmed a heavily calcified ostial flush SFA occlusion and showed an ostial calcified flap of

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DFA (Figure 1A-B). After few attempts to antegrade cross the SFA obstruction, retrograde 4

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access to the popliteal artery in the P1 segment was performed (Figure 1C). Before to reenter

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with the retrograde guidewire in CFA, a control angiogram showed the ostial occlusion of DFA

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precluding the safety guidewire advancement (Figure 1D). This unexpected finding was

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probably due to dislodgement of the underestimated ostial calcified DFA stenosis during SFA

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origin manipulation. Several antegrade attempts to cross the DFA occlusion with various

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guidewires and catheters were unsuccessfully made. Retrograde access was achieved by

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direct puncture of the DFA distally to the first perforating branch with a 20-gauge needle

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(Figure 2A). Since the diffuse DFA heavy calcification, the fluoroscopic-guided puncture was

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preferred over ultrasonographic technique, which represents the first choice in non-calcified

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arteries. With sheathless approach, the occlusion was crossed (Figure 2B) with a hydrophilic

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0.018 guidewire (V18, Boston Scientific, Natick, MA, USA) supported by a Berenstein II

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catheter (Tempo; Cordis Corporation, a Cardinal Health company, Milpitas, CA, USA). The

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retrograde guidewire was then externalized through the femoral sheath establishing a flossing

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wire (Figure 2C). Angioplasty with 4.0x40 balloon (Armada 18, Abbott, Santa Rosa, CA, USA)

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was than antegradely performed (Figure 2D). The balloon was placed in the puncture site

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after retrograde guide removal and replacement with a 0.014 guidewire (Hi-Torque

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Command™ ES, Abbott, Santa Rosa, CA, USA). The balloon was inflated at nominal

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pressure for 4 minutes to achieve hemostasis (Figure 2E). The control angiogram showed the

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patency of DFA with complete resolution of the ostial stenosis (Figure 2F). The SFA

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recanalization was interrupted because of patient discomfort. The patient had an

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uncomplicated recovery, with immediate resolution of rest pain probably due to the treatment

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of the unrecognized ostial DFA stenosis. Dual antiplatelet therapy (aspirin 100 mg and

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clopidogrel 75 mg once daily), started the day before the procedure, was continued for 3

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months and thereafter aspirin was prescribed long-life. At twelve-month clinical follow-up, no 5

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recurrent CLTI was present, and a duplex ultrasound examination showed the patency of

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DFA without significant restenosis or complications in the retrograde puncture site.

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Discussion

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Endovascular treatment of SFA lesions is rapidly extending its indication because of

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technological improvements of devices and operators experience. In the case of an SFA flush

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occlusion or a very short SFA stump, ostial engagement is often challenging and requires

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extensive management of catheters and guidewires. Whereas atherosclerotic lesions

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involving the SFA ostium often affect the femoral bifurcation, clearly the treatment of these

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lesions entails the risk of DFA damage. For this reason, during procedures involving SFA

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origin, a safety guidewire should always be positioned in DFA. This precaution allows for DFA

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protection and antegrade sheath stability.4

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In case of SFA occlusion, DFA represents the most essential collateral vessel to maintain

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limb viability, and then it is crucial to preserve its patency.5–8 When DFA accidental occlusion

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occurs without a safety guide in place, it could be impossible to pass through the lesion with a

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guidewire. In this case, retrograde access to the DFA is a useful bailout technique to rescue

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the vessel patency.

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The retrograde puncture of the DFA has been rarely described. There are only two reports in

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the literature for a total of four patients; all procedure published were planned (elective). Dacie

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et al.9 reported three cases of angioplasty of a stenosis at the DFA origin performed with

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retrograde approach. In all patients, the antegrade ipsilateral or contralateral approach was

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unfeasible for anatomic reasons. More recently, Megaly et al.10, treated a large CFA

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pseudoaneurysm through a retrograde DFA access. Also in this patient, the standard access

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was unsuitable. In none of these cases were observed complications at the access site. 6

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In the case presented in this report, the retrograde access was carried out as a bailout

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technique to rescue the DFA accidental occlusion. The diffuse dense parietal calcifications of

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DFA allow for a fluoroscopic-guided puncture given that ultrasounds are unable to accurately

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visualize the artery. Moreover, considering the DFA parietal characteristics, a sheathless

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approach was preferred to avoid injuries to the DFA and reduce risk of pseudoaneurysm in

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the access site. For the same reasons, the angioplasty was performed in antegrade fashion

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after externalization of the retrograde guidewire avoiding repeated catheters exchange

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through the sheathless access. The retrograde DFA access could be useful also when a

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safety guidewire is unfeasible such as during CFA directional atherectomy or ostial stenting of

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SFA with jailing of DFA.

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Conclusion

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Accidental occlusion of DFA is a rare but potentially catastrophic complication which could

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occur during antegrade recanalization of SFA flush occlusion. The retrograde DFA access is

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a useful bailout technique to restore the patency of DFA when unfeasible via antegrade route.

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Reference

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Megaly M, Sharma GK, Kumar A, Jones P. Endovascular Repair of a Large Common

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Cardiovasc Intervent Radiol. 2016;39(12):1792-1794. doi:10.1007/s00270-016-1408-0

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Figure legends

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Figure 1: Preprocedural angiograms demonstrate (A) the superficial femoral artery flush

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occlusion and the patency of the deep femoral artery (DFA) with diffuse heavy wall

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calcifications, and (B) the ostial calcified flap that determines tight stenosis. (C) The

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retrograde recanalization of the superficial femoral artery. (D) The control angiogram shows

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the DFA occlusion.

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Figure 2: Images that show: (A) the retrograde puncture of the deep femoral artery; (B)

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progression of the retrograde guidewire up to the common femoral artery; (C) externalization

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of the retrograde guidewire through the femoral sheath; (D) balloon angioplasty in antegrade

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fashion over the flossing wire; (E) endoluminal hemostasis; (F) final result with restoration of

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DFA patency and resolution of the ostial stenosis.

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