Rheumatology quiz

Indian Journal of Rheumatology 2011 March Volume 6, Number 1; p. 40

PG Forum

Rheumatology quiz Vivek Arya, Varun Dhir

1. Long-term remission rates in Behcet’s disease associated uveitis are highest with (a) azathioprine (b) corticosteroids (c) interferon α (d) cyclosporine A

6. Atypical femoral fractures seen in patients taking bisphosphonates most commonly affect the (a) shaft (b) neck (c) lower end (d) subtrochanteric region

2. In early secondary Raynaud’s phenomenon, nail fold capillaroscopy shows (a) increased capillary size (b) microhaemorrhages (c) loss of capillaries (d) neoangiogenesis

7. The lesions of urticarial vasculitis differ from those of urticaria in their (a) size (b) location (c) morphology (d) time to resolution

3. Levels of which of these markers are elevated in the early nail fold capillaroscopy changes of PSS? (a) anti-Scl 70 antibodies (b) anti-centromere antibodies (c) serum tissue kallikrein (d) urinary F2-isorostanes

8. The drug which has shown promise in treating osteonecrosis of the jaw following bisphosphonate use is (a) rituximab (b) teriparatide (c) cholecalciferol (d) methotrexate

4. Which of the following is not a feature of dermatomyositis associated with anti-Mi-2 antibodies? (a) acute onset (b) V-sign, shawl sign rashes are common (c) cuticular overgrowth (d) poor response to treatment

9. All the following are seen in Wegener’s granulomatosis, except (a) deficiency of TREG cells (b) decreased expression of CD25 on T cells (c) shift from CD4+ to CD8+ T cells (d) skewing towards CD4+ effector memory cells

5. Factors associated with severe infections one year following the first cycle of rituximab in RA include all, except (a) older age (b) extra-articular involvement (c) anti-CCP positivity (d) low IgG levels

10. Which of the following indices is used in the ACR/EULAR provisional definition of remission in rheumatoid arthritis for clinical trials? (a) DAS28 (b) MOI-RA (c) SDAI (d) CDAI For answers refer page 43