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Rhinoconjunctivitis and bronchial asthma due to monosensitization to Quercus pollen
S64 Abstracts
J ALLERGY CLIN IMMUNOL FEBRUARY 2004
SATURDAY 159
Rhinoconjunctivitis and Bronchial Asthma Due to Monosensitization to Quercus Pollen
J. Bartra1, M. San Miguel-Moncin2, M. Lombardero3, R. Alonso4, B. Fernández Parra4, R. Tella4, A. Cistero-Bahima4; 1Hospital Universitari de Girona Dr. Josep Trueta, Girona (Spain), SPAIN, 2Institut Universitari Dexeus, Barcelona, Barcelona, SPAIN, 3Departamento I+D; ALK-Abello, Madrid, SPAIN, 4Institut Universitari Dexeus, Barcelona, SPAIN. BACKGROUND: Quercus ilex and Quercus robur are two types of trees among fagaceas family. They show a cosmopolitan distribution and cause an important atmospheric pollinic rate between April and June. Nevertheless, sensitization to these types of pollens is unfrequent, and usually coexisting with other pollens sensitization
MATERIAL AND METHODS: Two patients suffering from rhinoconjunctivitis and seasonal bronchial asthma between April and June, came to our allergy department for an allergologic study. Prick tests to a battery of common aeroallergens and battery of pollens were performed. Specific conjunctival challenge test, determination of seric specific IgE levels and SDS-Page Immunoblotting were obtained. RESULTS: Prick test was positive to Quercus ilex and Quercus robur pollens in both patients. All other aeroallergens tested were negative. Specific IgE to Quercus ilex and Quercus robur was significant (>0.75 kU/L) in patient No. 1 and patient No. 2. Conjunctival challenge test to Quercus robur pollen was positive in both patients. Immunoblotting showed IgE fixing bands of 10 and 24 Kda against Quercus ilex pollen and 24 Kda against Quercus robur pollen in patient No. 1; in patient No. 2 a 50 Kda band against Quercus ilex pollen and 37 and 100 Kda bands against Quercus robur were observed. CONCLUSIONS: 1. We describe the first two cases of respiratory allergy due to monosensitization to Quercus pollen. 2. Quercus pollen should be considered as possible etiologic antigen in patients with respiratory symptoms and signs during its polinization season although no sensitization to other fagaceas pollen. Funding: Self-funded
Abstracts S65
SATURDAY
J ALLERGY CLIN IMMUNOL VOLUME 113, NUMBER 2
J ALLERGY CLIN IMMUNOL FEBRUARY 2004
SATURDAY 159
Rhinoconjunctivitis and Bronchial Asthma Due to Monosensitization to Quercus Pollen
J. Bartra1, M. San Miguel-Moncin2, M. Lombardero3, R. Alonso4, B. Fernández Parra4, R. Tella4, A. Cistero-Bahima4; 1Hospital Universitari de Girona Dr. Josep Trueta, Girona (Spain), SPAIN, 2Institut Universitari Dexeus, Barcelona, Barcelona, SPAIN, 3Departamento I+D; ALK-Abello, Madrid, SPAIN, 4Institut Universitari Dexeus, Barcelona, SPAIN. BACKGROUND: Quercus ilex and Quercus robur are two types of trees among fagaceas family. They show a cosmopolitan distribution and cause an important atmospheric pollinic rate between April and June. Nevertheless, sensitization to these types of pollens is unfrequent, and usually coexisting with other pollens sensitization
MATERIAL AND METHODS: Two patients suffering from rhinoconjunctivitis and seasonal bronchial asthma between April and June, came to our allergy department for an allergologic study. Prick tests to a battery of common aeroallergens and battery of pollens were performed. Specific conjunctival challenge test, determination of seric specific IgE levels and SDS-Page Immunoblotting were obtained. RESULTS: Prick test was positive to Quercus ilex and Quercus robur pollens in both patients. All other aeroallergens tested were negative. Specific IgE to Quercus ilex and Quercus robur was significant (>0.75 kU/L) in patient No. 1 and patient No. 2. Conjunctival challenge test to Quercus robur pollen was positive in both patients. Immunoblotting showed IgE fixing bands of 10 and 24 Kda against Quercus ilex pollen and 24 Kda against Quercus robur pollen in patient No. 1; in patient No. 2 a 50 Kda band against Quercus ilex pollen and 37 and 100 Kda bands against Quercus robur were observed. CONCLUSIONS: 1. We describe the first two cases of respiratory allergy due to monosensitization to Quercus pollen. 2. Quercus pollen should be considered as possible etiologic antigen in patients with respiratory symptoms and signs during its polinization season although no sensitization to other fagaceas pollen. Funding: Self-funded
Abstracts S65
SATURDAY
J ALLERGY CLIN IMMUNOL VOLUME 113, NUMBER 2