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RISK FACTORS ASSOCIATED WITH INFECTIVE ENDOCARDITIS AFTER AORTIC VALVE REPLACEMENT
1954 JACC March 21, 2017 Volume 69, Issue 11
Valvular Heart Disease RISK FACTORS ASSOCIATED WITH INFECTIVE ENDOCARDITIS AFTER AORTIC VALVE REPLACEMENT Moderated Poster Contributions Valvular Heart Disease Moderated Poster Theater, Poster Hall, Hall C Sunday, March 19, 2017, 12:30 p.m.-12:40 p.m. Session Title: Infectious Endocarditis: Comprehensive Perspectives Abstract Category: 36. Valvular Heart Disease: Clinical Presentation Number: 1313M-03 Authors: Lauge Østergaard, Nana Valeur Køber, Lars Køber, Nikolaj Ihlemann, Henning Bundgaard, Gunnar Gislasson, Christian Torp‑Pedersen, Niels Eske Bruun, Emil Loldrup Fosbøl, Rigshospitalet, Copenhagen, Denmark
Background: Patients undergoing aortic valve replacement (AVR) are considered at subsequent risk of infective endocarditis (IE), yet data on incidence of IE and associated factors are sparse.
Methods: Using nationwide registries in Denmark, all patients with no prior or current history of IE who underwent AVR Jan 1996-Dec 2012 were included. Patients were followed from hospital discharge after AVR to either death, end of study period (31th December 2012), or admission to hospital due to IE, whichever came first. Incidence of IE was described by 1, 5, and 10 years after AVR and factors associated with IE were analyzed using multivariable adjusted Cox proportional hazard analysis. Results: A total of 13,454 patients underwent AVR; 36.2% were women and the median age was 71.4 years, IQR: 63.4-77.2 years. Multivariable adjusted analyses identified factors associated with subsequent IE (see Figure). At 1, 5, and 10 years follow up after AVR we found that 1.5%, 3.3%, and 4.7% were rehospitalized due to IE. We found that male gender, bioprosthetic aortic valve, pacemaker at AVR surgery, and diabetes with complications were among factors associated with an increased risk of IE (see Figure). Conclusions: IE was not uncommon in patients undergoing AVR. Male gender, bioprosthetic valve, pacemaker, and diabetes with complications were among factors associated with subsequent risk of infective endocarditis.
Valvular Heart Disease RISK FACTORS ASSOCIATED WITH INFECTIVE ENDOCARDITIS AFTER AORTIC VALVE REPLACEMENT Moderated Poster Contributions Valvular Heart Disease Moderated Poster Theater, Poster Hall, Hall C Sunday, March 19, 2017, 12:30 p.m.-12:40 p.m. Session Title: Infectious Endocarditis: Comprehensive Perspectives Abstract Category: 36. Valvular Heart Disease: Clinical Presentation Number: 1313M-03 Authors: Lauge Østergaard, Nana Valeur Køber, Lars Køber, Nikolaj Ihlemann, Henning Bundgaard, Gunnar Gislasson, Christian Torp‑Pedersen, Niels Eske Bruun, Emil Loldrup Fosbøl, Rigshospitalet, Copenhagen, Denmark
Background: Patients undergoing aortic valve replacement (AVR) are considered at subsequent risk of infective endocarditis (IE), yet data on incidence of IE and associated factors are sparse.
Methods: Using nationwide registries in Denmark, all patients with no prior or current history of IE who underwent AVR Jan 1996-Dec 2012 were included. Patients were followed from hospital discharge after AVR to either death, end of study period (31th December 2012), or admission to hospital due to IE, whichever came first. Incidence of IE was described by 1, 5, and 10 years after AVR and factors associated with IE were analyzed using multivariable adjusted Cox proportional hazard analysis. Results: A total of 13,454 patients underwent AVR; 36.2% were women and the median age was 71.4 years, IQR: 63.4-77.2 years. Multivariable adjusted analyses identified factors associated with subsequent IE (see Figure). At 1, 5, and 10 years follow up after AVR we found that 1.5%, 3.3%, and 4.7% were rehospitalized due to IE. We found that male gender, bioprosthetic aortic valve, pacemaker at AVR surgery, and diabetes with complications were among factors associated with an increased risk of IE (see Figure). Conclusions: IE was not uncommon in patients undergoing AVR. Male gender, bioprosthetic valve, pacemaker, and diabetes with complications were among factors associated with subsequent risk of infective endocarditis.