Septicemic complications of the cutaneous T-cell lymphomas

Septicemic complications of the cutaneous T-cell lymphomas

_ bacillary meningitis bacillary menin adults. Am J Diabetes mellitus ratios in diabetes mellitus and bac- Meningitis Although calculation of th...

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_ bacillary meningitis

bacillary menin adults. Am J

Diabetes mellitus

ratios in diabetes

mellitus and bac-

Meningitis

Although calculation of the cerebrospinal fluid to serum glucose ratio is widely recommended as a way to identify pathologic hypoglycorrhachia. few data are available to document its accuracy. In order to provide a better basis for interpreting this quotient, simultaneous cerebrospinal fluid and serum glucose concentrations from patients with diabetes mellitus and noninflammatory cerebrospinal fluid and patients with acute bacterial meningitis were compared. Cerebrospinal fluid to serum glucose ratios were significantly lower in the patients with meningitis. A ratio of 0.31 provided the best differentiation between the two groups. In 45 of 64 patients with meningitis, ratios were below this level, including 10 in whom the absolute cerebrospinal fluid glucose concentration was not below 40 mg/dl. In 35 of 36 uninfected diabetic subjects, ratios were 0.31 or greater. In tfte sole exception, concentrated glucose solution had been given intravenously shortly before lumbar puncture. Use of the cerebrospinal fluid to serum ratio, in addition to the absolute cerebrospinal fluid glucose concentration, increases sensitivity in detecting pathologic hypoglycorrhachia with little loss in specificity.

Powers WJ: Cerebrospinal fluid to serum glucose terial meningitis. Am J Med 1981; 71: 217-220.

Cerebrospinal fluid

In an eight year period (1972-1979) 158 cases of enteric gram-negative bacillary meningitis and 53 cases of Listeria meningitis were reported to the New York City Health Department. These two forms of bacterial meningitis were the fourth and fifth most common ones reported to the Department, respectively. The cumulative total of reported cases of gram-negative rod meningitis was only slightly less than the reported cases due to Neisseria meningitis over this period. In contrast to most previous studies of Listeria and enteric gram-negative meningitides, the majority of cases occurred in adults. The over-all mortality in Listeria meningitis was 62 percent and in the combined gram-negative meningitides 7 1.3 percent. The only appreciable survival rates were in those with Listeria. Escherichia coli, Proteus mirabilis and Salmonella meningitis who were treated with ampicillin alone in whom the over-all mortality was 51 percent.

Cherubin CE, Marr JS, Sierra MF, Becker S: Listeria and gram-negative ingitis in New York City, 1972-1979. Frequent causes of meningitis Med 1981: 71: 199-209.

Salmonella meningitis

Gram-negative

Klebsiella meningitis

Escherichia coli meningitis

Listeria

Sepsis

Antimicrobial therapy

complications

Cancer

of the cuta-

Contractility

hy-

In 14 patients suffering from primary hyperkinetic heart syndrome, intravascular and ultrasound evaluations were repeated at yearly intervals for five years. During this period, seven subjects (group I) were untreated, and seven (group II) received propranolol. The study was undertaken to test whether (1) hypertrophic subaortic stenosis is a complication of the syndrome; and (2) very prolonged normalization of the circulatory regimen by propranolol promotes an irreversible circulatory adjustment. Septal and left ventricular posterior wall thickness remained normal for the duration of the follow-up both in group II (in which persistent circulatory normalization was documented) and in group I (in which cardiac hyperkinesis was unchanged or increased). Overactivity of the heart promptly reappeared in group II when, at the end of the trial, placebo was substituted for propranolol. Data indicate that transition toward hypertrophic cardiomyopathy probably is not a feature of the syndrome and that prolonged circulatory normalization by propranolol does not extinguish the disorder.

follow-up of the primary

Hypertrophic subaortic stenosis

Fiorentini C, Olivari MT, Moruzzi P, Guazzi MD: Long-term perkinetic heart syndrome. Am J Med 1981; 71: 221-227.

Anxiety

The records of 60 consecutive patients with cutaneous T-cell lymphomas were reviewed to determine the incidence, etiology, predisposing factors, therapy, complications and outcome of septicemia. Fourteen patients had 26 septicemias: due to gram-positive cocci in 21 and to gram-negative bacilli in five. The presence of stage IV lymphomatous disease (p = 0.032), generalized erythroderma (p
Posner LE, Fossieck BE, Eddy JL, Bunn PA Jr.: Septicemic neous T-cell lymphomas. Am J Med 1981; 71: 210-216.

Septicemia

Cutaneous T-cell lymphomas