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Short-Term Functional Outcomes for Total Knee Arthroplasty in Diabetic Patients: A Prospective, Control-Matched Comparison
e68 The Journal of Arthroplasty Vol. 25 No. 3 April 2010
Poster #23 Short-Term Functional Outcomes for Total Knee Arthroplasty in Diabetic Patients: A Prospective, Control-Matched Comparison Todd A. Morrison, MS, William B. Macaulay, MD, Jeffrey A. Geller, MD Introduction: Patients with diabetes mellitus (DM) are at an increased risk for surgical morbidity. Previous studies have attempted to compare TKA outcomes for diabetic and non-diabetic patients but may not have fully accounted for differences in preoperative functional status. The purpose of this study was to perform a prospective, case control-matched comparison of functional outcomes for TKA in diabetic and non-diabetic patients while controlling for differences in baseline function. Methods: A cohort of patients with type II DM undergoing TKA (dTKA) was randomly matched to a control group of non-diabetic patients undergoing TKA (ndTKA) on the basis of age ( ± 5 years), gender, and preoperative WOMAC physical function (PF) score ( ± 10). Patients without a primary diagnosis of osteoarthritis were excluded. SF-12 and WOMAC assessments were collected preoperatively and at 3-months follow-up. Data was analyzed using t tests, χ 2 analyses, and multivariate linear regression models. Results: A total of 35 diabetic TKAs were randomly matched to 35 non-diabetic TKAs. At 3-months follow-up, the dTKA group exhibited significantly lower SF-12 function (P = .035) and WOMAC PF (P = .048) scores than the ndTKA group. When controlling for the effects of age, gender, and BMI, the presence of DM had a significantly negative effect on the outcome of SF-12 function scores (P = .044). The overall complication rate for the dTKA cohort was significantly higher (χ 2 = .01) than that for the ndTKA cohort. In the dTKA cohort, stiff/painful TKAs and manipulations under anesthesia (MUA) were the most common complications. MUA occurred solely in the dTKA cohort. Conclusions: Our results indicate that diabetic patients undergoing TKA have poorer outcomes at early follow-up and are more likely to suffer postoperative complications than non-diabetic patients in this cohort. This data may be important when counseling patients about the potential risks of surgical intervention in the face of DM.
Poster #23 Short-Term Functional Outcomes for Total Knee Arthroplasty in Diabetic Patients: A Prospective, Control-Matched Comparison Todd A. Morrison, MS, William B. Macaulay, MD, Jeffrey A. Geller, MD Introduction: Patients with diabetes mellitus (DM) are at an increased risk for surgical morbidity. Previous studies have attempted to compare TKA outcomes for diabetic and non-diabetic patients but may not have fully accounted for differences in preoperative functional status. The purpose of this study was to perform a prospective, case control-matched comparison of functional outcomes for TKA in diabetic and non-diabetic patients while controlling for differences in baseline function. Methods: A cohort of patients with type II DM undergoing TKA (dTKA) was randomly matched to a control group of non-diabetic patients undergoing TKA (ndTKA) on the basis of age ( ± 5 years), gender, and preoperative WOMAC physical function (PF) score ( ± 10). Patients without a primary diagnosis of osteoarthritis were excluded. SF-12 and WOMAC assessments were collected preoperatively and at 3-months follow-up. Data was analyzed using t tests, χ 2 analyses, and multivariate linear regression models. Results: A total of 35 diabetic TKAs were randomly matched to 35 non-diabetic TKAs. At 3-months follow-up, the dTKA group exhibited significantly lower SF-12 function (P = .035) and WOMAC PF (P = .048) scores than the ndTKA group. When controlling for the effects of age, gender, and BMI, the presence of DM had a significantly negative effect on the outcome of SF-12 function scores (P = .044). The overall complication rate for the dTKA cohort was significantly higher (χ 2 = .01) than that for the ndTKA cohort. In the dTKA cohort, stiff/painful TKAs and manipulations under anesthesia (MUA) were the most common complications. MUA occurred solely in the dTKA cohort. Conclusions: Our results indicate that diabetic patients undergoing TKA have poorer outcomes at early follow-up and are more likely to suffer postoperative complications than non-diabetic patients in this cohort. This data may be important when counseling patients about the potential risks of surgical intervention in the face of DM.