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Sinus bradycardia with cardiac asystole
ically three clays later, confirmed the presence of myocarditis; it persisted for two days in spite of digitalis therapy and ultimately changed to auricular flutter. Anatomic and histologic findings at autopsy revealed an acute myocarditis with formation of ante-mortem mural thrombi. Here, then, is an example of auricular fibrillation and auricular flutter developing as. terminal events in the course of an extremely acute myocnrditis. AUTHOR.
Cookson, I-I.: Heart Block and the Simulation .I-. 7: 6.3, 1945.
of Bundle
Block in Diphtheria.
Brit. Heart
Clinical and cardiographic findings are given of eight cases showing conduction changes among a series of eight,y-three patients with diphtheria. Of four with latent block, a prolonged P-R interval has persisted in one for five months. Bundle branch block was observed in four unimmunized children, aged 12 years or lpss, and all died; complete block was recorded in one of these four. In two others bizarre ventricular complexes were found in association with a passive ectopic rhythm; at first sight these suggest a bundle branch lesion, but like the short P.R wide QRX syndrome, which seems a related condition, these changes do not appeal to have any prognostic significance. AUTHOR.
?ewson,
R. S. B.:
Sinus Bradycardia
With
Cardiac
Asystole.
Brit.
Heart
J. 7: 85, 1945.
A case of persistent sinus bratlycartliu with syncopal attacks due to cardiac standstill is described. Evidence is given for believing that this is not vagal in origin but due to hypo-excitability nf the pacemaker. .kLlTHOR.
Costero, and Fuertes, G. A.: Frequency of Congenital Anatomic Lesions the City of Mexico. Arch. Inst. (.“:trdiol. Mex. 14: 275, 7945.
of the Heart
in
In 1,000 consecutive autopsies with a complete pathologic study recorded in the Service of Pathology of the General Hospital of Mexico and carried out for Sept. 11, 1937, to Jan. 19, 1941, the frequency of congenital anatomic lesions of the heart and of the large vessels has been investigated with the following results: 1. Fenestration of the sigmoid valves was found in 253 cases. In 107 of them the lesion was of the pulmonary sigmoid; in 67, of the aortic sigmoid; and in 79, of the valves of both arteries. Of these cases 48 (18.97 per cent) coincided with other congenital abnormalities in the organism. 2. The foramen of Botal was incompletely closed in 1.79 cases, of which 80 (44.69 per cent) coincided with other congenital malformations. 3. The coronary arteries were abnormal in 36 cases; in 14 there were accessory corenaries; in eight there was duplicity in the opening of one of the coronaries; in two there were multiple openings; and in 12 the opening was displaced. The following abnormalities were found only once. 4. Bivalve sigmoid, which coincided with other extracardiae congenital malformations. 5. Incomplete interauricular septum, coinciding also with other malformations. 6. Bifurcation of the apex, associated with fenestration of the sigmoid. 7. Dilatation of coronary sinus. In 90 of the cases tabulated there were two simultaneous lesions, and, in five of them, there were three simultaneous congenital lesions of the cardiovascular system. AIWEORS.
Grolnick, M., and Loewe, L.: Immunologic Studies in Patiepts With Subacute Bacterial Endocarditis Treated by Combined Penicillin-Heparin Method. J. Lab. & Clin. Med. 30: 559, 1945. Twenty-seven patients receiving intensive and prolonged treatment with penicillin failed to develop any positive akin or ophthalmic reactions to a solution of penicillin contaiaing These patients did not ddvelop any positive skin reactions 10,000 units per cubic centimeter. to the source of this product, the mold Penicillti?n notakm. From the present study penicillin would appear to be a very poor sensitizing agent. AUTHORS.
Cookson, I-I.: Heart Block and the Simulation .I-. 7: 6.3, 1945.
of Bundle
Block in Diphtheria.
Brit. Heart
Clinical and cardiographic findings are given of eight cases showing conduction changes among a series of eight,y-three patients with diphtheria. Of four with latent block, a prolonged P-R interval has persisted in one for five months. Bundle branch block was observed in four unimmunized children, aged 12 years or lpss, and all died; complete block was recorded in one of these four. In two others bizarre ventricular complexes were found in association with a passive ectopic rhythm; at first sight these suggest a bundle branch lesion, but like the short P.R wide QRX syndrome, which seems a related condition, these changes do not appeal to have any prognostic significance. AUTHOR.
?ewson,
R. S. B.:
Sinus Bradycardia
With
Cardiac
Asystole.
Brit.
Heart
J. 7: 85, 1945.
A case of persistent sinus bratlycartliu with syncopal attacks due to cardiac standstill is described. Evidence is given for believing that this is not vagal in origin but due to hypo-excitability nf the pacemaker. .kLlTHOR.
Costero, and Fuertes, G. A.: Frequency of Congenital Anatomic Lesions the City of Mexico. Arch. Inst. (.“:trdiol. Mex. 14: 275, 7945.
of the Heart
in
In 1,000 consecutive autopsies with a complete pathologic study recorded in the Service of Pathology of the General Hospital of Mexico and carried out for Sept. 11, 1937, to Jan. 19, 1941, the frequency of congenital anatomic lesions of the heart and of the large vessels has been investigated with the following results: 1. Fenestration of the sigmoid valves was found in 253 cases. In 107 of them the lesion was of the pulmonary sigmoid; in 67, of the aortic sigmoid; and in 79, of the valves of both arteries. Of these cases 48 (18.97 per cent) coincided with other congenital abnormalities in the organism. 2. The foramen of Botal was incompletely closed in 1.79 cases, of which 80 (44.69 per cent) coincided with other congenital malformations. 3. The coronary arteries were abnormal in 36 cases; in 14 there were accessory corenaries; in eight there was duplicity in the opening of one of the coronaries; in two there were multiple openings; and in 12 the opening was displaced. The following abnormalities were found only once. 4. Bivalve sigmoid, which coincided with other extracardiae congenital malformations. 5. Incomplete interauricular septum, coinciding also with other malformations. 6. Bifurcation of the apex, associated with fenestration of the sigmoid. 7. Dilatation of coronary sinus. In 90 of the cases tabulated there were two simultaneous lesions, and, in five of them, there were three simultaneous congenital lesions of the cardiovascular system. AIWEORS.
Grolnick, M., and Loewe, L.: Immunologic Studies in Patiepts With Subacute Bacterial Endocarditis Treated by Combined Penicillin-Heparin Method. J. Lab. & Clin. Med. 30: 559, 1945. Twenty-seven patients receiving intensive and prolonged treatment with penicillin failed to develop any positive akin or ophthalmic reactions to a solution of penicillin contaiaing These patients did not ddvelop any positive skin reactions 10,000 units per cubic centimeter. to the source of this product, the mold Penicillti?n notakm. From the present study penicillin would appear to be a very poor sensitizing agent. AUTHORS.