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Sleep and biological rhythms; basic mechanisms and applications to psychiatry
Book Reviews Current Protocols in Immunology. Volume l--Edited by J. COLIGAN, A. M. KRUISBEEK, D. M. MARGULIFS, E. M.
SHEVACHand W. STROBER.1991. 880 pp. John Wiley/ Greene, New York. $240 (shipping charge $5 USA; $30 elsewhere). This is a loose leaf format in a hard binder, so that the year’s two additional updates (of 100-150 pages each) can be inserted. The editors are from NIH and there are 90 contributors. It is a practical manual giving precise instructions on how to carry out specific procedures. The main sections are on: care and handling of laboratory animals; antibody detection and preparation; in vitro assays for mouse B and T cell function; in viz.0assays for mouse T cell function; immunoflorescence and cell sorting; cytokines and their cellular receptors; immunologic studies in humans and isolation and analysis of proteins. This volume will be very useful to all laboratories that use any immunological techniques. Immunodiagnosis
of Cancer. 2nd Edition--Edited
by R. B. HERBMAN andD. W. MERCER.712 pp. 1990. Marcel Dekker, New York. $150 U.S.A. and Canada. $180 elsewhere. Since the first edition there have been many new markers developed and their clinical interpretation has become more skilled. In addition there has been a change of emphasis, and cancer is now considered not as a unique disease, but as a shift in the antigenic composition of normal cells. The level of tumor (T) markers only becomes easily detectable when there are a substantial number of tumor cells or metastatic spread. Methods are being developed to increase the sensitivity of the detection systems. The book deals with experimental design; statistical methods; mutivariate tech-
411
niques; use of multiple markers; serum and tissue banks for markers; MAb for breast carcinoma associated mucins; enzyme immunoassays; enhanced detection systems; fiber optic evanescent wave immunosensors; electrochemical detection; luminescence detection; organ site directed tumor markers (breast epithelial antigens; lymphomas; pancreatic T; melanoma; CNS T; ovarian T; prostate T; head and neck T; uterine T: testicular T: heoatocellular T: bone T: thyroid’ T; lung T; renal cell T; bladder T); use of im: munoglobulins; acute phase reactant proteins; immune complexes; incipient T, serum enzymes; mucin glycoproteins and placental proteins. Sleep and Biological Rhythms; Basic Mechanisms and Applications to Psychiatry-Edited by J. MONPLAISIRand R. G~DIKIUT.240 pp. 1990. Oxford University Press, New
York. $49.95. The topics discussed in this book include: circadian system and sleep-wake behavior; biological rhythms; effects of wakefulness and sleep on depression and mania (lack of sleep can reduce depression the next day; but 90 minutes of sleep may bring it back); extended sleep in man; assessment of endogenous circadian pace maker in man; bright light and melatonin; twilight therapeutics, winter depression (strong light can sometimes overcome winter depression), melatonin and sleep; brain stem cholinergic system; thalamic transfer of signals during dreaming sleep; sleep neuromodulators (muramyl peptides, poly (LC), IL-l, interferon alpha 2, tumor necrosis factor, GRF, VIP, PHI-GH, PRL, CRF); cholinergic mechanisms; chronic insomnia and restless legs syndrome, sleep and narcolepsy. This book is interesting enough to keep you awake.
SHEVACHand W. STROBER.1991. 880 pp. John Wiley/ Greene, New York. $240 (shipping charge $5 USA; $30 elsewhere). This is a loose leaf format in a hard binder, so that the year’s two additional updates (of 100-150 pages each) can be inserted. The editors are from NIH and there are 90 contributors. It is a practical manual giving precise instructions on how to carry out specific procedures. The main sections are on: care and handling of laboratory animals; antibody detection and preparation; in vitro assays for mouse B and T cell function; in viz.0assays for mouse T cell function; immunoflorescence and cell sorting; cytokines and their cellular receptors; immunologic studies in humans and isolation and analysis of proteins. This volume will be very useful to all laboratories that use any immunological techniques. Immunodiagnosis
of Cancer. 2nd Edition--Edited
by R. B. HERBMAN andD. W. MERCER.712 pp. 1990. Marcel Dekker, New York. $150 U.S.A. and Canada. $180 elsewhere. Since the first edition there have been many new markers developed and their clinical interpretation has become more skilled. In addition there has been a change of emphasis, and cancer is now considered not as a unique disease, but as a shift in the antigenic composition of normal cells. The level of tumor (T) markers only becomes easily detectable when there are a substantial number of tumor cells or metastatic spread. Methods are being developed to increase the sensitivity of the detection systems. The book deals with experimental design; statistical methods; mutivariate tech-
411
niques; use of multiple markers; serum and tissue banks for markers; MAb for breast carcinoma associated mucins; enzyme immunoassays; enhanced detection systems; fiber optic evanescent wave immunosensors; electrochemical detection; luminescence detection; organ site directed tumor markers (breast epithelial antigens; lymphomas; pancreatic T; melanoma; CNS T; ovarian T; prostate T; head and neck T; uterine T: testicular T: heoatocellular T: bone T: thyroid’ T; lung T; renal cell T; bladder T); use of im: munoglobulins; acute phase reactant proteins; immune complexes; incipient T, serum enzymes; mucin glycoproteins and placental proteins. Sleep and Biological Rhythms; Basic Mechanisms and Applications to Psychiatry-Edited by J. MONPLAISIRand R. G~DIKIUT.240 pp. 1990. Oxford University Press, New
York. $49.95. The topics discussed in this book include: circadian system and sleep-wake behavior; biological rhythms; effects of wakefulness and sleep on depression and mania (lack of sleep can reduce depression the next day; but 90 minutes of sleep may bring it back); extended sleep in man; assessment of endogenous circadian pace maker in man; bright light and melatonin; twilight therapeutics, winter depression (strong light can sometimes overcome winter depression), melatonin and sleep; brain stem cholinergic system; thalamic transfer of signals during dreaming sleep; sleep neuromodulators (muramyl peptides, poly (LC), IL-l, interferon alpha 2, tumor necrosis factor, GRF, VIP, PHI-GH, PRL, CRF); cholinergic mechanisms; chronic insomnia and restless legs syndrome, sleep and narcolepsy. This book is interesting enough to keep you awake.