THE DIFFUSION OF SMALL-POX.
1456
septal artery alone; it was observed in 18 per cent. with ligation of the arteria coronaria dextra, in 50 per cent. with ligation of the descendens, and in 80 per cent. with ligation of the arteria circumflexa. Ligation of two of the above-named arteries failed to stop the ventricles in 5 out of 14
the leucocytes ceasing in two hours as they did in the first series of experiments, they continued for at least eight hours. An interesting fact was here noted, that although the virulence of the microbes was diminished, and they seemed to be by the leucocytes, yet their reproductive properties were not affected and fresh subcultures were easily obtained.
devoured
In each of the 5 the coronaria dextra was one of the arteries tied. Ligation of three arteries invariably caused standstill. The number of seconds during which the heart continued to beat after ligation varied with the artery occluded. With ligation of the coronaria dextra the time in 3 cases was, respectively, 1C02, 1008, and 343 seconds ; with the descendens the average duration of activity in 8 cases was 233 seconds ; with the circumflexa the average was 119 seconds. Stand-still did not occur more quickly after ligation of a second or a third artery than afterI ligation of a single artery. When stand-still did not follow ligation the frequency of the ventricular beat was seldom changed. When stand-still followed ligation, frequency was sooner or later usually altered. But some hearts beat with unchanged rhythm to the last. As a rule, both ventricles stopped at the same moment, no matter which ventricle the ligated arteries supplied. Fibrillary contractions followed arrest of action instantly or within a very few seconds, and finally the arrest of action was always permanent. cases.
INTERNATIONAL MEDICAL CONGRESS, ROME, 1894. FROM Rome, under date Dec. 4th, our own correspondent writes : "The Char6d’Affaires of the Argentine Republic at the Court of the Quirinal has informed the Minister for Foreign Affairs that the medical faculty of Buenos Ayres and the Board of Public Health of that capital have nominated Dr. Francesco Silveyra to represent them in clinical medicine and hygiene respectively in the sections dealing with those subjects at the coming Congress."
MEDICAL SICKNESS ASSURANCE IN FRANCE.
THE Seine Medical Mutual Association, which has now been in existence six years, has reason to congratulate its members, who now number 280, on its success and on its usef ulness-100, 000 francs having already been placed in the The arrangements differ somewhat from those reserve fund. to which we are accustomed. Thus, all the members, whatTHE DIFFUSION OF SMALL-POX. ever their ages may be at the time of joining, pay the same in IN the provinces small-pox is still slowly extending, and premium-10 francs monthly-and sick members all receive some of the larger towns previously infected the disease a similar amount daily throughout the whole time they are ill. maintains itself with a great deal of tenacity. In Walsall It is stated that one member, who has been obliged to give there were last week 36 fresh attacks, as opposed to 45 in the up practice on account of locomotor ataxy, has received week ending Nov. 25th ; in Birmingham the number was 69; 10 francs a day during the past financial year. Bradford, 41; Aston Manor, 15; Bristol, 13 ; West Bromwich, 9 ; West Ham, 6 ; Wakefield, 6 ; Wimbledon, 6 ; OldSMALL-POX IN SCOTLAND.
ham, 5 ; Middlesbrough, 4 ; Handsworth, 4; Leicester, 4; Chatham, 3 ; and minor occurrences in a number of other places, such as Bolton, Chadderton, Derby, Worcester, Smethwick, and Bath. In the metropolis there were 32 fresh attacks last week, and the total number of cases of small-pox isolated by the Metropolitan Asylums Board managers was about 130, this number representing a slight diminution.
Small-pox has unfortunately become epidemic in Leith, and The accommodation available i.3 are already in hospital. now practically at an end, and the authorities are seeking some building by which their hospitals may be supplemented.
28
IODOFORM AND PUS FORMATION.
months Scotland has been practically free from but the disease has now broken out with coiisiderable severity in Leith. Within the past fortnight no less that 40 cases have occurred, and the existing hospital accommodation is being taxed to its utmost. The cholera hospital is being prepared for the reception of small-pox patients, and a temporary wooden structure, to receive 40 cases, is to be proceeded with at once. Free vaccination is being adopted. As Leith is a very important shipping centre and has constant inland communication with all parts of the country, it will be necessary for the Scotch sanitaryauthorities to prepare themselves once more to deal with impotted cases of the disease. FoR
some
small-pox,
___
DR. MANSEL has made an interesting series of observaPARLIAMENT AND THE INFLUENZA. tions1 on the action of iodoform in preventing suppuraTHE unmistakable reappearance of influenza in its typical He watched the action of leucocytes on a warm tion. and which a virulent culture of disabling form in London has a most important bearing stage amongst staphylococcus on the prolongation of the present session of Parliament. been had introduced. A number of the microbes pyogenes were absorbed by the leucocytes, but the latter were destroyed We all know how severely and disproportionately its members in about two hours. Dr. Mansel is of opinion that this suffered on a former occasion. How much more may they destruction of leucocytes is due not to any mechanical be expected to do so in the depth of winter and the gloom action on the part of the staphylococcus, but to the toxines of shortening days, after a yearof unexampled labour ? evoked by the microbe. Iodoform was then mixed with blood Very serious loss of health, and even life, may be expected, in the proportion of 0’10 to 0 25 per kilogramme of blood ; the perhaps in members on whose ability and judgment the leucocytes were not, however, affected by the drug injuri- country is relying for years of important service. There ously-on the contrary, the activity of their movements seemed is no denying that, apart from influenza, Parliamentary Mr. to be increased. In another series of experiments he mixed work nowadays is exhausting to all but strong men. iodoform with cultures of staphylococcus pyogenes aureus Gladstone’s unique strength misleads him and misleads the and staphylococcus pyogenes albus, but the organisms public as to the limitations of the physical powers of members, underwent no change. He then subjected the leucocytes on which the amount and character of the legislative work of and cultures of these microbes together to the action of the country depends. The prolongation of the session and the iodoform, and found that the virulence of the staphylococcus shortening of the brief interval of holiday to follow thus was certainly diminished; for, instead of the movements of become questions of great national moment. They are by no means to be settled on political principles, but on physio1
Bulletin Général do
Thérapeutique.
logical and medical considerations
of
great urgency.