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SPMO 8101 Sonographic features in the diagnosis of diffuse goiter
S146
Ultrasound
in Medicine
and Biology
Volume 23, Supplement
SPMO 8005
SPMO 8102
COLOR DOPPLER FLOW IN SUPERFICIAL MELANOMA METASTASES: HISTOLOGIC CORRELATION
ULTRASONICALLY OF SECONDARY M.Elwertowski Ultrasound Dept. POLAND
Alexan&,& Nszarian. LN, Capuzzi, Kurtz, AB. Duhow, BE
D, Rawool,
NM,
PURPOSE: To determine whether tumor vessel size or nnmhcr affects color Doppler flow detection in superficial melanoma metastsses. MATERIALS AND METHODS: Seven subcutaneous (n= 5) and superficial nodal (n= 2) melanoma metastascs in six patients were scanned with color Doppler US at 6 MHz. Color Doppler parameters were optimized for each lesion, and umscncc or absence of interns1 flow documented. Followinn &icsl removal, the metastascs underwent immunohistochemicsl staining for endothclial markers (Factor VIII and CD-34). For each lesion the number of tumor vessels (100X magnification) and diameter of the largest vessel (4COX magnification) were recorded. RESULTS: Four metsstases contained intcmsl color Doppler flow. and 3 did not. Histolonv showed the maximum vessel diamctcr to be significantly &ater (p&05) in lesions with flow, 73.6p +/- 19..5u, than in those without flow, 40.7u +/1 1.1 u. However. the mean number of tumor vessels in lesions with flow. 44.7 +/- 19.2, was not significantly different from those without flow, 63.5 +/- 50.6. CONCLUSION: Detectability of color Doppler flow in superficial melanoma metsstascs may be r&ted more to vessel diameter than to vessel number. However, further investigation is needed due to the small sample size.
SPMO 8101 SONOGRAPHIC
1, 1997
GUIDED ABLATION THERAPY PARATHYROID ADENOMAS Infectious
Diseases
Hosp.
Warsaw
Secondary hyperparathyreoidism is frequently encountered in permanently dialysed patients being result of phosphate retention and depression of intestinal calcium absorbtion. Material of our work consists of 21 patients with significant alterations of calcium & PTH serum levels (with PTH level over 400 mg/l) in whom ultrasound examination revealed l-4 cervical parathyroid adenomas varying in size from 6x4mm to 42x27mm. All pathological changes were injected with 96% apyrogen alcohol given in 2 parts during each session in total volume 1,5-2x exceeding the volume of hyperplastic glands. The procedure was usually repeated after l-3 months. Total amount of 34 tumors were cured with 70 injection attempts (54 complete injection, 12 partial injection, 4 failures). Clinical improvement & 3-4x decreased PTH level was observed in I5 patients, partial improvement in 4 while in 2 crises trere was no positive effect of alcoholisation. Repeated - 2 injections /I session ablation procedure enhances positive alcohol effect. Colour/power Doppler was extremely helpful in both initial study - demonstrating intratumoral & peripheral vessels in 29/34 adenomas as well as during repeated procedures (26/36). However its value was most pronounced in immediate control studies following ablation when flow was present in 8/70 tumors failures & partial injections. It was also a perfect indicator of active tumor in cases of repeated procedure of patients with multiple hyperplasia.
SPMO 8103 FEATURES IN THE DIAGNOSIS DIFFUSE GOITER
OF
Morikawa
P, Vera de Rufflnelli J, Monzdn Ml, Medina U, Boaado YL. Frutos IB. Moreno Azorero R. Instlluto‘de lnve&igaciones en Cienclas de la SaludUniversidad National de Aaunci6n, Aauncion-Paraguay. The purpose of this study was to determine sonographic features of diffuse goiter in order to differentiate thyroid dysfunctional disease from a simple endemic goiter. Fifly cases of diffuse goiter from a consecutive sample of 172 studies of thyroid ultrasonography were selected. Frequencies of sonographic parameters such as ecogenicity, ecotexture, contours and lobular thickness were determined. Besides, clinical laboratory tests, mainly serum levels of FT4, TSH and TPO ab were also measured in order to establish significant associations between groups according to the ecogeniclty and the dysfunctional parameters measured. The significance of differences between proportions was determined using Chi-square test. Twenty seven (54%) cases were Iso or Hiperecogenic (Group I) and 23 (46%) were hipoecogenic (Group II). Heterogeneous ecostructure (p
1NNER THYROID Esteves, Irapuan CARDIOLAH-ECOLAB
FOREIGN
- Rio de Janeiro
Patient complaining of mass, painful to handling, months evolution. Normal Diagnostic l l l l l l l
physical
BODY
- Brazil
front left cervical With approximately
tumoral three
examination
Investigation
Normal thyroidal hormones Normal full blood count and biochimestry Normal chest X-Ray Normal eletrocardiography Normal carcinoembrionaty antigen Thyroid cintilography:Diffuse goiter Biopsy:Inflammatoty response
Ultrassonografic report of the thyroid presented a linear echogenic structure sorrounded by a hypoechoic area at the left lobe, compatible with foreign body and resultant inflammatory response. A fish bone was found after to a left hand side lobectomy.
the patient
was submitted
Ultrasound
in Medicine
and Biology
Volume 23, Supplement
SPMO 8005
SPMO 8102
COLOR DOPPLER FLOW IN SUPERFICIAL MELANOMA METASTASES: HISTOLOGIC CORRELATION
ULTRASONICALLY OF SECONDARY M.Elwertowski Ultrasound Dept. POLAND
Alexan&,& Nszarian. LN, Capuzzi, Kurtz, AB. Duhow, BE
D, Rawool,
NM,
PURPOSE: To determine whether tumor vessel size or nnmhcr affects color Doppler flow detection in superficial melanoma metastsses. MATERIALS AND METHODS: Seven subcutaneous (n= 5) and superficial nodal (n= 2) melanoma metastascs in six patients were scanned with color Doppler US at 6 MHz. Color Doppler parameters were optimized for each lesion, and umscncc or absence of interns1 flow documented. Followinn &icsl removal, the metastascs underwent immunohistochemicsl staining for endothclial markers (Factor VIII and CD-34). For each lesion the number of tumor vessels (100X magnification) and diameter of the largest vessel (4COX magnification) were recorded. RESULTS: Four metsstases contained intcmsl color Doppler flow. and 3 did not. Histolonv showed the maximum vessel diamctcr to be significantly &ater (p&05) in lesions with flow, 73.6p +/- 19..5u, than in those without flow, 40.7u +/1 1.1 u. However. the mean number of tumor vessels in lesions with flow. 44.7 +/- 19.2, was not significantly different from those without flow, 63.5 +/- 50.6. CONCLUSION: Detectability of color Doppler flow in superficial melanoma metsstascs may be r&ted more to vessel diameter than to vessel number. However, further investigation is needed due to the small sample size.
SPMO 8101 SONOGRAPHIC
1, 1997
GUIDED ABLATION THERAPY PARATHYROID ADENOMAS Infectious
Diseases
Hosp.
Warsaw
Secondary hyperparathyreoidism is frequently encountered in permanently dialysed patients being result of phosphate retention and depression of intestinal calcium absorbtion. Material of our work consists of 21 patients with significant alterations of calcium & PTH serum levels (with PTH level over 400 mg/l) in whom ultrasound examination revealed l-4 cervical parathyroid adenomas varying in size from 6x4mm to 42x27mm. All pathological changes were injected with 96% apyrogen alcohol given in 2 parts during each session in total volume 1,5-2x exceeding the volume of hyperplastic glands. The procedure was usually repeated after l-3 months. Total amount of 34 tumors were cured with 70 injection attempts (54 complete injection, 12 partial injection, 4 failures). Clinical improvement & 3-4x decreased PTH level was observed in I5 patients, partial improvement in 4 while in 2 crises trere was no positive effect of alcoholisation. Repeated - 2 injections /I session ablation procedure enhances positive alcohol effect. Colour/power Doppler was extremely helpful in both initial study - demonstrating intratumoral & peripheral vessels in 29/34 adenomas as well as during repeated procedures (26/36). However its value was most pronounced in immediate control studies following ablation when flow was present in 8/70 tumors failures & partial injections. It was also a perfect indicator of active tumor in cases of repeated procedure of patients with multiple hyperplasia.
SPMO 8103 FEATURES IN THE DIAGNOSIS DIFFUSE GOITER
OF
Morikawa
P, Vera de Rufflnelli J, Monzdn Ml, Medina U, Boaado YL. Frutos IB. Moreno Azorero R. Instlluto‘de lnve&igaciones en Cienclas de la SaludUniversidad National de Aaunci6n, Aauncion-Paraguay. The purpose of this study was to determine sonographic features of diffuse goiter in order to differentiate thyroid dysfunctional disease from a simple endemic goiter. Fifly cases of diffuse goiter from a consecutive sample of 172 studies of thyroid ultrasonography were selected. Frequencies of sonographic parameters such as ecogenicity, ecotexture, contours and lobular thickness were determined. Besides, clinical laboratory tests, mainly serum levels of FT4, TSH and TPO ab were also measured in order to establish significant associations between groups according to the ecogeniclty and the dysfunctional parameters measured. The significance of differences between proportions was determined using Chi-square test. Twenty seven (54%) cases were Iso or Hiperecogenic (Group I) and 23 (46%) were hipoecogenic (Group II). Heterogeneous ecostructure (p
1NNER THYROID Esteves, Irapuan CARDIOLAH-ECOLAB
FOREIGN
- Rio de Janeiro
Patient complaining of mass, painful to handling, months evolution. Normal Diagnostic l l l l l l l
physical
BODY
- Brazil
front left cervical With approximately
tumoral three
examination
Investigation
Normal thyroidal hormones Normal full blood count and biochimestry Normal chest X-Ray Normal eletrocardiography Normal carcinoembrionaty antigen Thyroid cintilography:Diffuse goiter Biopsy:Inflammatoty response
Ultrassonografic report of the thyroid presented a linear echogenic structure sorrounded by a hypoechoic area at the left lobe, compatible with foreign body and resultant inflammatory response. A fish bone was found after to a left hand side lobectomy.
the patient
was submitted