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Squamous Cell Carcinoma of the Tongue
PATH TO PATIENT IMAGE QUIZ
Squamous Cell Carcinoma of the Tongue Lori A. Erickson, MD
T
he image below shows structures resected for deeply invasive squamous cell carcinoma extensively involving the tongue and extending to abut the larynx.
From the Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN.
Which statement about these tumors is most accurate?
a. Oral tongue cancer is often diagnosed at an advanced stage, unlike cancer of the base of the tongue b. Squamous cell carcinomas of the base of the tongue may be associated with human papillomavirus
c. Tongue carcinomas are usually adenocarcinomas d. The prognosis for oropharyngeal carcinoma is based only on nodal stage
(see page 1172 for answer) Mayo Clin Proc. n July 2017;92(7):1171-1172 n http://dx.doi.org/10.1016/j.mayocp.2017.05.022 www.mayoclinicproceedings.org n ª 2017 Mayo Foundation for Medical Education and Research
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MAYO CLINIC PROCEEDINGS
Answer: b. Squamous cell carcinomas of the base of the tongue may be associated with human papilloma virus
Oral tongue cancer tends to be diagnosed when the tumor is small and more easily removed, while cancer of the base of the tongue is often diagnosed at a more advanced stage. Squamous cell carcinomas of the base of the tongue may be associated with human papillomavirus, which can have an effect on prognosis and treatment.1 The prognosis for oropharyngeal carcinoma is based on human papillomavirus status, smoking history, tumor stage, and nodal stage. Microscopy shows squamous cell carcinoma infiltrating skeletal muscle.
REFERENCE 1. Sivars L, Bersani C, Grün N, et al. Human papillomavirus is a favourable prognostic factor in cancer of unknown primary in
1172
Mayo Clin Proc.
n
the head and neck region and in hypopharyngeal cancer. Mol Clin Oncol. 2016;5(6):671-674.
July 2017;92(7):1171-1172
n
http://dx.doi.org/10.1016/j.mayocp.2017.05.022 www.mayoclinicproceedings.org
Squamous Cell Carcinoma of the Tongue Lori A. Erickson, MD
T
he image below shows structures resected for deeply invasive squamous cell carcinoma extensively involving the tongue and extending to abut the larynx.
From the Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN.
Which statement about these tumors is most accurate?
a. Oral tongue cancer is often diagnosed at an advanced stage, unlike cancer of the base of the tongue b. Squamous cell carcinomas of the base of the tongue may be associated with human papillomavirus
c. Tongue carcinomas are usually adenocarcinomas d. The prognosis for oropharyngeal carcinoma is based only on nodal stage
(see page 1172 for answer) Mayo Clin Proc. n July 2017;92(7):1171-1172 n http://dx.doi.org/10.1016/j.mayocp.2017.05.022 www.mayoclinicproceedings.org n ª 2017 Mayo Foundation for Medical Education and Research
1171
MAYO CLINIC PROCEEDINGS
Answer: b. Squamous cell carcinomas of the base of the tongue may be associated with human papilloma virus
Oral tongue cancer tends to be diagnosed when the tumor is small and more easily removed, while cancer of the base of the tongue is often diagnosed at a more advanced stage. Squamous cell carcinomas of the base of the tongue may be associated with human papillomavirus, which can have an effect on prognosis and treatment.1 The prognosis for oropharyngeal carcinoma is based on human papillomavirus status, smoking history, tumor stage, and nodal stage. Microscopy shows squamous cell carcinoma infiltrating skeletal muscle.
REFERENCE 1. Sivars L, Bersani C, Grün N, et al. Human papillomavirus is a favourable prognostic factor in cancer of unknown primary in
1172
Mayo Clin Proc.
n
the head and neck region and in hypopharyngeal cancer. Mol Clin Oncol. 2016;5(6):671-674.
July 2017;92(7):1171-1172
n
http://dx.doi.org/10.1016/j.mayocp.2017.05.022 www.mayoclinicproceedings.org