anti-green streptococcus seru111. Tl1e reactions following the use of any one of these three types of serun1 were irrrgula1 and while at times severe,...
anti-green streptococcus seru111. Tl1e reactions following the use of any one of these three types of serun1 were irrrgula1 and while at times severe, were geu crally mild and produced no injury to tl1e patient. No well-defined improvements could be observed following the use of sera. The authors point out that it is uot to be expected that any marked specific beneficial action would follow antistreptococcus serum therapy in rheumatic fever, for the disease is not of tl1c general type wl1irh would respond favorably to a serum. It is 11ot an acute disease like diphtheria, tetanus or scarlet fever but a subacute or chronic infection resembling tuberculosis or syphilis in many of its features. The amount of material xsponsiblc for the various manifestations of the disease which are elaborated and conveyed to the blood varies in amount and intensity over long periods of time. The autl1ors conclude that antistreptococcus serum in 110 way should replace the long rst:1blished therapy of rl1cur1u~tic fever and that it does not apparently add enough to warrant its universal adoption. In their experiments the unpleasant reactions sometimes nttendn11t upon its al1plieation have not been outbalanced by :L reciprocal certainty of thrr:1prutic benefit.
Leech, Clifton 180:
631,
B.: Streptococcus
Viridans
Endocarditis
in Children.
Ar11. J. M.
8e.
1930.
Tire records of the Harriet Lane Home revealed 13 illstances of streptococcus viridans endocarditis proved by blood culture or by autopsy, 2 unproved but highly probable cases and 1 streptocnccus viridans septicemia without endocarditis. The 15 cases represent an incidence of approximately 0.1 per rent. An analysis of these records is partially indicated in the accompanying table. A discussion of the symptoms and signs indicates tl1at this infection produces a clear clinical diagnosis even without picture of sufficiently constant characteristics to permit culture of the blood.
Fishberg, Arthur M.: Auricular Fibrillation and Flutter in Metaetatic of the Right Auricle. -4m. .J. M. SC. 180: 629, 1, 1930.
Growths
Tl1ree cases are described in whicl1 secondary nmlignant grovvths in the auricle were accompanied by auriculx fibrillation or flutter. In the first of Cases tl1e involvement of the right auricle by the tumor was suspected during in tl1e two succeeding cases this diagnosis was considered very probable.
Sheldon, Wilfrid:
Rheumatism
in Childhood.
J,anwt
right these life;
11: 394, 1930.
This paper is based on the notes of six 11undred consecutive cases of rl1eunmtism seen during the last two years at the Rheumatic Clinic of the Hospital for Sick Children, Great Ornlond Street. The children were divided into tl1e following four groups. One group was of 235 children with rheumatic pains in the limbs. These children form an important group, because of the possibility of a later development of heart disease. The pains rarely develop before the age of three years. They are especially frequent during tl1e night, and they occur in many parts of the body, chiefly the legs. An accompanying curve shows that tl1e pains occur more frequently during the seasons when there is greater rainfall. Fift,y-two of 26F children with rheumatic heart disease complained of these pains as the only symptoms preceding the discovery of the heart disease; similarly 15 children out of 197 cases of ehorea gave a history of such pains in the limbs.