Subject index of volume 66

Steroids 66 (2001) 915–918

Subject Index of Volume 66 Acetolysis, 623 Acetylenic alcohols, 569 Activation function 2 domain, 203 Adenocarcinoma, 287 Adrenal steroids, 883 Adrenal tumor, 817 Affinity chromatography, 529 Affinity labeling, 189 Alcohols, 777 Allopregnanolone, 55, 99 1␣,25-Dihydroxy-2␤-(3-hydroxypropoxy)vitamin D3, 267 1␣,25-dihydroxyvitamin D3, 203, 267, 287, 539 1␣,25-Dihydroxyvitamin D4, 93 3␣,12␣-Dihydroxy-7-oxo-5␤-cholan-24-oic acid, 63 3␣,7␣-Dihydroxy-12-oxo-5␤-cholan-24-oic acid, 63 1␣-Hydroxylase, 409, 451 3␣-Hydroxy-7,12-dioxo-5␤-cholan-24-oic acid, 63 1␣,23(S),25(OH)3-24-oxo-D3, 423 1␣,25(OH)2-3-epi-D3, 441 1␣,25(OH)2-16-ene-D3 analogs, 327 1␣,25(OH)2D3, 137, 147, 227, 339, 347, 363, 409, 423, 441, 451, 463 1␣,25(OH)2D3 (calcitriol), 293 1␣,25(OH)2D3 analogs, 357 1␣,25-(OH)2D3-26,23-lactone analogues, 227 5␣-Reductase, 521 Analgesia, 811 Analogs, 223, 463 Androgen receptor, 293 Androgen receptor binding, 833 Androgens synthesis, 645 Androstenedione, 609 Ansa-steroids, 239 Antagonist, 227 Antibody production, 539 Apoptosis, 277, 301, 309, 327 A-ring conformation, 277 Aromatase, 511, 749 Ascomycetes, 771 Atherosclerosis, 473, 673 4-Azasteroids, 803 Behavior, 99 16␤-(Acetoxy)acetoxylation, 743 16␤-Acetoxylation, 743 17␤-Estradiol, 529 11␤ Hydroxysteroid dehydrogenase, 49, 845 ␤-Oxidation, 499 Bile, 93 Bile acid, 107 Bile acid biosynthesis, 499 Bile acid synthesis, 637 Biliary excretion, 701 Biological activity, 803 Biotin, 609 Biotine, 81 Bone, 257, 375 Bone resorption, 347 Brain, 865, 883 Branched DNA, 663 Breast cancer, 59, 301 Breast neoplasm, 905

PII: S 0 0 3 9 - 1 2 8 X ( 0 1 ) 0 0 1 6 6 - 0

C-24 Oxidation pathway, 451, 463 C-3 Epimerization pathway, 441, 463 Ca2⫹ signaling, 505 Calcitroic acid, 93 Calcium, 849 Calcium channels, 347, 357 cAMP, 39 Cancer, 319 Cancer cell lines, 319 Cancer cells, 433 26-Carboxy-1␣,24,25-trihydroxyvitamin D4, 93 28-Carboxy-1␣,24,25-trihydroxyvitamin D4, 93 Catechol estrogen, 615 Cbfa1, 159 Cell cycle, 223, 327 Cell differentiation, 227 Cell maturation, 683 Cell proliferation, 319 Chemical synthesis, 499, 821 Chinese truffles, 771 Chirality, 803 Chlorinated steroid, 25 Cholestenoic acid, 473 Cholesterol, 473, 673 Cholesterol 7␣-hydroxylase, 637 Cholic acid, 63 Chondrocyte cultures, 683 Chondrocytes, 363 Chromatin, 159 Clavularia viridis, 25 13 C-NMR spectroscopy, 249 Coactivators, 171, 213 Competitive RT-PCR, 87 Configurational analysis, 833 Conformation, 147 Conjugated reaction, 107 Conjugated steroids, 795 Corepressors, 213 Corticosterone, 845, 883 Cortisol, 737, 795, 817, 883 Cortisol metabolites, 795 Cortisone, 817 Covalent [3H]luteolin binding, 707 cPLA2, 309 Cushing’s disease, 817 CYP24, 409, 433, 451 CYP27, 399 Cyst fluid, 55 Cytochrome P450, 391 Cytochrome P450 aromatase, 763 Cytokine, 319 Cytotoxic activity, 785 Cytotoxicity, 897 DAST, 99 Daunorubicin conjugates, 785 D-Azasteroids, 655 D-bifunctional protein, 107 Dehydrocholic acid, 63 11-Dehydrocorticosterone, 845 Dehydroepiandrosterone sulfate, 865

916

Subject Index / Steroids 66 (2001) 915–918

Development, 883 Dexamethasone, 39 Dibutyltin, 763 Diels-Alder reaction, 249 Diethylstilbestrol, 505 Differentiation, 287, 327 Dimerization, 203 25-Dihydroxyvitamin D3, 277 1,3-Dipolar cycloaddition, 569 D-Secosteroids, 645 EB1089, 539 ED-71, 137, 267 Eisai hyperbilirubinemic rats, 701 Electrochemical anodic oxidation, 63 17-Enol acetoxy steroid, 743 Enzyme, 381 Enzyme activity, 529 Enzyme immunoassay, 59, 539 Enzyme-linked immunosorbent assay, 865 Epalon, 99 20-epi analog, 203 20-epi-2-methyl-1␣, 277 3-Epimers, 327 Epitestosterone, 55 ER mRNA, 905 Estradiol, 71, 511, 821, 889 Estrogen, 59, 301, 605, 663, 749 Estrogen receptor, 549, 905 Estrogen receptor ␣, 1, 17, 695 Estrogen receptor binding, 785 Estrone, 811 Ether and alkyl carbonate derivatives of 7-oxygenated steroids, 581 Extremophiles, 49 Fallopian tube, 87 Fecal metabolites, 875 Fibroblasts, 857 Follicle, 511, 889 FSH, 511 Fungi, 49 Fura-2, 505 GABAA receptor, 99, 655 Gas chromatography, 759 Gel shift clipping assay, 213 Gene expression, 597 Gene regulation, 381 GHRH, 71 Glucocorticoids, 597, 749 ␤-Glucuronidase, 795 Glucuronosides, 581 Glyceraldehyde-3-phosphate dehydrogenase (GAPDH), 529 Gonadotropins, 559 Gorgonian, 721, 897 Granulosa, 511 Granulosa cells, 889 Growth hormone, 71 Growth plate, 363 1

H NMR spectroscopy, 99 Hapten, 539 Helical peptides, 549 HL-60 cell differentiation, 277 HL-60 cells, 227, 423 Homology modeling, 177, 189 Hormone-binding analysis, 189 HPLC analysis, 107 Human, 87, 763 Human breast cancer cells, 309

Human keratinocytes, 409, 441 Human large intestine, 287 Human prostate, 521 Human serum, 59 Hybrid, 257 Hydrocortisone, 811 Hydrolysis, 795 2-hydroxyestrone, 59 4-Hydroxyestrone, 615 4-Hydroxyestrone 3-methyl ether, 615 24-Hydroxylated ED-71, 267 25-Hydroxylase, 399 16-Hydroxymethyl-5␣-androstane-3␤,17-diol, 623 17␣-Hydroxypregnenolone, 759 17-hydroxypregnenolone, 81, 759 4-Hydroxy-6-oxoestrone, 615 25-Hydroxyvitamin D3, 399 7-Hydroxy steroids, 117 7␤-Hydroxydehydroepiandrosterone, 581 Hydroxysteroid dehydrogenase, 821 Hypercholesterolemia, 673 Hyperglycemia, 597 Hypertension, 695 IGF-I, 309 Immunocytochemistry, 727 Immunohistochemical staining, 87 Immunohistochemistry, 905 In situ hybridization, 905 Indomethacin, 857 Inflammatory periodontal repair, 857 Inhibition, 451 Inhibition of aromatase activity, 645 Inhibitors, 409, 803 Insulin, 511 Insulin resistance, 559 Internal bypass, 637 Intestinal factor, 637 Isihippurols A and B, 721 Isis hippuris, 721 Isotope-labeling, 743 Keratinocyte differentiation, 339 Keratinocytes, 399, 451 KH-1060, 137 Kyotorphin, 811 Lactones, 777 L-bifunctional protein, 107 Lead (IV) acetate, 743 Lignans, 777 Limited protease digestion assay, 213 Linker, 811 Lipid environment, 521 Liver, 605 Liver X receptor, 473 Livial, 117 LXR, 673 Mammary gland, 301 Mass spectrometry, 759 MC-903, 137 MDCK cells, 505 Membrane ER-␣, 727 Menopause, 559 Mesophiles, 49 Metabolism, 423, 441, 463, 605 Metabolites, 93, 375, 463 4-Methoxyestrone, 615 2-Methyl-1␣, 277

Subject Index / Steroids 66 (2001) 915–918 24-Methylenecholest-4-en-3␤,6␤-diol, 33 16-Methyl steroids, 833 Michael reactions, 777 Mineralocorticoid, 817 Molecular modeling, 249, 803 Monobutyltin, 763 Monoclonal antibodies, 1 Moxestrol, 605 mRNA quantitation, 17 Multidrug resistance protein 2, 701 Mutation, 381 Natural metabolites, 423 Neighboring group participation, 623 Nitrile oxides, 569 NMR data, 821 19-Norsteroids, 569 Nuclear ER-␣, 727 Nuclear matrix, 159 Nuclear receptor, 147, 171, 177 Nuclear receptor conformations, 213 Nuclear receptors, 673 Obesity, 559 OCT, 137 25-OH-D3-24-hydroxylase, 227 17OH-Progesterone, 737 Oocyte, 849 ORG OD14, 117 Organic anions, 701 Osteoarthritis, 749 Osteoblasts, 357, 663 Osteocalcin, 159, 347 Osteopontin, 357 Osteoporosis, 137, 257 Osteosarcoma cells, 347 Ovulatory cycle, 889 3-O-␤-D-Glucopyranosyl-(22E, 24R)-ergosta-7, 22-die, 771 7-Oxo-dehydroepiandrosterone, 581 24-Oxo-5␤-cholestan-26-oyl CoA, 499 Oxysterol, 473 P450, 381 p53, 905 Parathyroid hormone, 357 Peptidosteroid, 821 Phosphatidylmonomethylethanolamine, 849 Phospholipase C-␥1, 339 Phospholipase D, 683 Phospholipases, 521 Phospholipids, 521 Phosphonate, 257 Plasma membrane, 849 Plexaurella grisea, 897 p-Nitrophenol, 727 Point mutation, 189 Polyclonal antibodies, 1 Polyhydroxylated sterol, 33 Polyhydroxysteroids, 721 Preeclampsia, 695 Pregnancy, 695, 875 Pregnanes, 875 Pregnenolone sulfate, 55 Progesterone, 529, 737, 849 Progesterone receptor, 663 Proliferation, 287, 433 Promoter, 381 Promoter selectivity, 213 Prostate cancer, 293 Protease, 849 Protein aggregation, 549

917

Protein dimerization, 549 Protein kinase C, 683 Protein-DNA interaction, 213 Psoriasis, 137 Purification of nuclear type II [3H]estradiol binding sites, 707

Quantitative plate assay, 727

24(R),25(OH)2D3, 363, 683 24R-Hydroxylase, 391 Rapid actions, 363 Rapid responses, 147 Rat, 319, 637, 865 Rational design, 549 Reaction mechanism, 743 Receptor, 223 Regioselectivity, 63 Remote functionalization, 481 Renal tubular cells, 505 Rhinoceros, 875

Saliva, 737 Selective estrogen receptor modulator, 663 Selective synthesis, 615 Serum, 865 Side chain conformation, 249 Signal transduction, 683 Soft coral, 25 Spirofurans, 569 Splice targeted primers, 17 Splice variants, 17 SRIF, 71 Stability, 737 Stable isotope, 759 Steroid, 71, 99, 107, 257, 293, 381, 399, 409, 481, 499, 549, 559, 597, 605, 663, 673, 695, 727, 759, 763, 817, 821, 857, 889 Steroid hormones, 171 Steroid hydroxylases, 391 Steroid inactivation, 845 Steroid metabolism, 391 Steroid receptors, 287 Steroid sulfatase, 87 Steroid sulfate, 473 Steroidal non-steroidal estrogen ligand, 785 Sterol, 249, 267, 771, 897 Structural elucidation, 25 Structure-function relationship, 177 Suprasterols, 239 Synoviocytes, 749 Synthesis, 33, 277, 539, 655, 777, 785

T lymphocytes, 39 Tamoxifen, 605 Tauroursodeoxycholate-3-sulfate, 701 Template competition RT PCR, 17 Testosterone, 71 Testosterone 5␣ reductase, 803 Tetrabutyltin, 763 Tibolone, 117 Time-resolved fluoroimmunoassay, 81, 609 TNF␣, 309, 319 trans-Activation, 597 Transcription, 159 Transcription regulation, 171 Transcriptional activity, 327 Tributyltin, 763 Tuber indicum, 771 Tuberoside, 771 Tyrosine aminotransferase, 597

918

Subject Index / Steroids 66 (2001) 915–918

VDR, 137 VDR binding affinity, 277 Vitamin D, 147, 177, 213, 223, 239, 257, 301, 319, 363, 375, 391, 399, 433 Vitamin D analogs, 137, 249, 293, 309, 319 Vitamin D receptor, 171, 203, 293, 363 Vitamin D receptor agonists, 213 Vitamin D receptor ligand-binding domain (structure), 189 Vitamin D signalling pathways, 213

Vitamin D steroid, 159 Wagner-Meerwein rearrangement, 623 Women, 749 Yeast, 49 Yonarasterol, 25