SUN-P073: Bioelectrical Impedance Analysis in Patients Undergoing Hematopoietic Stem Cell Transplantation

SUN-P073: Bioelectrical Impedance Analysis in Patients Undergoing Hematopoietic Stem Cell Transplantation

Nutrition and cancer 1 body weight for 4 hours once a week for up to six months. Blood samples were collected to assess omega-3 PUFA uptake into plasm...

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Nutrition and cancer 1 body weight for 4 hours once a week for up to six months. Blood samples were collected to assess omega-3 PUFA uptake into plasma non-esterified fatty acids (NEFAs) and phosphatidylcholine (PC) and into red blood cell (RBC) membranes. Fatty acid profiles were analysed by gas chromatography. Results: Twenty patients with at least one Omegaven® treatment were included in the intention to treat analysis. Each infusion of omega-3 PUFAs resulted in increased EPA and DHA in plasma NEFAs, but there was little effect on PUFAs within plasma PC during the infusions. However, with repeated weekly infusion of omega-3 PUFAs, the EPA content of plasma PC and of RBC membranes increased. Conclusion: Repeated weekly omega-3 PUFA infusion is safe in patients with advanced oesophagogastric cancer receiving palliative chemotherapy, and is effective in enriching plasma PC and RBC membranes in EPA. Disclosure of Interest: A. Eltweri Grant/Research Support from: Fresenius-Kabi, A. Thomas: None declared, H. Fisk: None declared, P. Calder Speaker Bureau of: Fresenius-Kabi, A. Dennison Grant/ Research Support from: Fresenius-Kabi, Speaker Bureau of: FreseniusKabi, D. Bowrey Grant/Research Support from: Fresenius-Kabi

SUN-P072 CREATION OF A MULTICENTER ONCOLOGIC NUTRITION GROUP S. T. K. Cerqueira1, E. Y. Hirose1, A. L. C. C. Rodrigues1, F. N. Peixoto1, A. N. Severine1. 1Nutrition, Hospital Sirio Libanes, São Paulo, Brazil Rationale: Creation of a multicenter study group formed by dietitians, from public and private institutions, to share experiences and improve knowledge in the pursuit of best professional practices. Methods: In 2012, the dietitians from Oncologic Center, with the team of Coordination and Management of the Food Service, created the NutriOnco group. This group was responsible to develop protocols, review institutional nutritional recommendations and oncologic menus; contributing to shape a permanent educational and professional training space for dietitians and catering staff. From this internal initiative, in 2014, the dietitians spread the idea with other institutions which demonstrated interest and availability to participate; simultaneously laboratories have become partners to support the events. Results: Topic discussed per meeting and number of participant institutions: Presentation of the Group’s proposal/4, Introduction of the participating institutions/6, Immunopressed diet/14;Immunonutrients in Oncology/11, Gastronomy applied in Oncology/11,Immunologic Prepare/12,The Oncological Pediatric Patient/13, GVHD diet protocols/9, When should start a dietary supplement?/11,Use of probiotics in oncology/12. Conclusion: The integration between the institutions promotes a better discussion of clinical practices, contributes and encourages clinical research and the dissemination of the knowledge in this area. References [1] Ministério da Saúde, Instituto Nacional do Câncer. Estimativa de Câncer no Brasil, 2016. Coordenação de Prevenção e Vigilância/ Divisão de Vigilância. [2] CARO M.M.M. et al. Nutritional intervention and quality of life in adult oncology patients. Clinical Nutrition, v. 26, p. 289–301, 2007.

S71 [3] PINHO N.B. et al. Terapia Nutricional na Oncologia. In: Sociedade Brasileira de Nutrição Parenteral e Enteral; Associação Brasileira de Nutrologia. Projeto diretrizes. Associação Médica Brasileira; Conselho Federal de Medicina Volume IX. Brasília: 2011. p. 127–141. Disclosure of Interest: None declared

SUN-P073 BIOELECTRICAL IMPEDANCE ANALYSIS IN PATIENTS UNDERGOING HEMATOPOIETIC STEM CELLTRANSPLANTATION J. B. Barban1, M. Tanaka1, A. P. N. Barrére1, F. Lucio1, J. M. Nabarrete1, S. M. F. Piovacari1, N. Hamerschlak2, A. Pereira2. 1Department of Clinical Nutrition, 2Oncology and Hematology Department, Hospital Israelita Albert Einstein, São Paulo, Brazil Rationale: The Bioelectrical Impedance Analysis (BIA) estimates the phase angle, fat and lean body mass. Low phase angle by BIA, is associated with increased morbidity and nutritional risk. The nutritional status of patients undergoing Hematopoietic stem cell transplantation (HSCT) is a prognostic indicator of this procedure. Study and correlate lean body mass, fat mas and phase angle in patients undergoing the HSCT. Methods: It was performed a retrospective study, from May 2015 to January 2016, in 38 patients undergoing HSCT. The said study took place at the Hematology-Oncology and Bone Marrow Transplantation Center of the Albert Einstein Hospital in São Paulo, Brazil. All patients were submitted to bioimpedance analysis prior to HSCT, and the data was analyzed using the SPSS program. Results: The study observed 21 elderly patients (>55 y) and 17 adults patients (<55 y). In this pool, 52.6% were female and 47.4 male, having a mean age of 55.2 ± 14.3 years, lean body mass of 71.1 ± 7.9%, fat mass of 28.9 ± 7.9% and phase angle of 5.6 ± 1.02°. The bioimpedance test did not show sarcopenia in patients. Moreover, a negative correlation between years and phase angle (rp = 0.5) was observed. In addition, the study presented a significant association between phase angle and elderly ( p < 0.05). Finally, no significant difference among lean mass, fat mass, and survival was observed. Conclusion: This study shows that elderly patients have a significant association with low phase angle when compared with adult patients undergoing HSCT. As literature evidences suggest, low phase angle, is associated with increased morbidity and nutritional risk. Therefore, a preventive nutritional care should be applied to elderly patients that will be submitted to a HSCT. Disclosure of Interest: None declared

SUN-P074 TUMOR-INDUCED HYPOGLYCEMIA(TIH) SYMPTOMS CONTROLLED BY PARENTERAL NUTRITION AND INTRAVENOUS GLUCAGON INFUSION(IGI): A CASE REPORT IN OVARY CANCER A. Z. Pereira1, A. M. Gomes Filho1, J. S. B. Barban2, F. C. Maluf1. 1 Oncology, 2Nutrition, Hospital Israelita Albert Einstein, São Paulo, Brazil Rationale: Hypoglycemia, an unusual clinical disorder not associated with diabetes, is diagnosed by a plasma glucose