- Email: [email protected]
SUN-P080: Change in Body Composition and Nutrient Intake after Chemotherapy Treatment of Breast Cancer Patients
S74 This study confirms this result also in non-hospitalized cancer patients having HPN carried out by a trained caregiver. It should be noted that caregiver’s training must be performed by highly qualified nursing staff. Disclosure of Interest: None declared
SUN-P080 CHANGE IN BODY COMPOSITION AND NUTRIENT INTAKE AFTER CHEMOTHERAPY TREATMENT OF BREAST CANCER PATIENTS E. Chae1, J. Baek 1, M. Rha1, Y. Cho1. 1Clinical Nutrition Part, Samsung Medical Center, Gangnam-gu, Seoul, Republic of Korea Rationale: The aim of this study was to investigate the changes in weight, body composition and nutrient intake after adjuvant chemotherapy treatment of breast cancer patients. Methods: Analyses of outcomes was conducted on 111 subjects with nutrition counseling after chemotherapy between March and May 2010 among breast patients with nutrition counseling before adjuvant chemotherapy. The anthropometric and biochemical data, nutrient intake were measured before and after chemotherapy treatment. All data were analyzed using PASW 18.0 with a significance of 95%. Results: The result of the study indicated that the body weight was not changed between before and after chemotherapy treatment, despite the tendency of weight gain after treatment. However, the body composition significantly changed, with a mean loss of 0.53 kg fat free mass (38.89 ± 3.78 kg vs 38.36 ± 3.78 kg, p < 0.05). Especially, within 6 months after the end of treatment, the patients showed highly significant change in body composition, with a mean loss of 0.34 kg FFM and a mean 2.1% increase in percent body fat, from 29.25 ± 4.79% to 31.32 ± 4.57% ( p < 0.05). Energy intake was not significantly changed after adjuvant chemotherapy treatment (1621.34 ± 376.35 kcal vs 1566.45 ± 319.14 kcal), whereas protein intake was significantly decreased after the chemotherapy treatment (61.04 ± 20.45 g vs 55.4 ± 16.24 g, p < 0.05). On the other hand, increased intake of cereals and oils group comprised significant percent of total calorie intake. Conclusion: This study showed unfavorable changes in body composition without weight change for breast cancer patients receiving adjuvant chemotherapy treatment whereas protein intake was significantly decreased. Taken together, it is necessary to counsel in the nutritional aspect as soon as possible, to minimize the change in body composition after chemotherapy. Disclosure of Interest: None declared
SUN-P081 THE INFLUENCE OF ADIPOSE TISSUE-SECRETED FACTORS ON THE PROGRESSION OF MALNUTRITION OF ONCOLOGICAL PATIENTS - PRELIMINARY RESULTS E. Sobczak1,2, S. Małgorzewicz1, W. J. Kruszewski2,3. 1 Department of Clinical Nutrition and Dietetics, Medical University of Gdańsk, Gdańsk, 2Department of Surgical Oncology, Gdynia Oncology Centre, Gdynia, 3Department of Oncology Propedeutics, Medical University of Gdańsk, Gdańsk, Poland Rationale: Malnutrition in patients with gastrointestinal cancer is mainly associated with muscle mass reduction. However,
Poster research shows that fat loss occurs even more rapidly and to a greater extent than loss of muscle tissue. Better understanding of the complex role of adipose tissue in development of cancer related malnutrition may be crucial for the development of cancer cachexia-specific markers and methods of its treatment. Methods: We present the preliminary results of a study conducted on 63 gastrointestinal adenocarcinoma patients and 20 from control group. Median age of 66.4 and median BMI 25.37 ± 4.7. The nutritional status was screened with NRS 2002, apetite with SNAQ and performance status with Karnofsky Scale. Samples collected from visceral adipose tissue for the future measurements of concentrations of selected hormones and inflammatory markers. The biochemical tests were tested before the procedure. Statistical analysis with Spearman rank correlation was performed. Results: The preliminary results indicate a statistically significant correlation between the presence and the severity of gastrointestinal adenocarcinoma and the nutritional status recorded by NRS 2002 (r = 0.62), BMI (r = −0.27), Karnofsky Scale (r = −0.52) and apetite (r = −0.59). There also was a statistically significant correlation between the size of tumour (T) and the nutritional status recorded by NRS 2002 (r = 0.41), BMI (r = −0.31), apetite(r = −0.42) and Karnofsky scale (r = −0.49). Similiar results were obtained when comparing the presence and number of metastases to the lymph nodes and distant metastases. The median albumin concentration in the examined group was 36.23 ± 11.47 g/L. Conclusion: The preliminary results indicate a correlation between the degree of malnutrition (NRS 2002, SGA), BMI, apetite and Karnofsky scale and the presence and the severity of gastrointestinal adenocarinoma. Disclosure of Interest: None declared
SUN-P082 LOW ADHERENCE TO DIETARY RECOMMENDATIONS IN ADULT CHILDHOOD CANCER SURVIVORS F. N. Belle1,2, L. Wengenroth3, A. Weiss1, G. Sommer1, M. Beck Popovic4, M. Ansari5, M. Bochud2, C. E. Kuehni1, on behalf of the Swiss Paediatric Oncology Group (SPOG). 1Institute of Social and Preventive Medicine, University of Bern, Bern, 2 Division of Chronic Diseases, Institute of Social and Preventive Medicine, Lausanne University Hospital CHUV, Lausanne, Switzerland; 3Institute of Occupational, Social and Environmental Medicine, Ludwig-Maximilians-Universtität, Munich, Germany; 4Paediatric Haematology-Oncology Unit, Lausanne University Hospital CHUV, Lausanne, 5Department of Paediatrics, Onco-Haematology Unit, Geneva University Hospital HUG, Geneva, Switzerland Rationale: Poor diet may increase the risk that childhood cancer survivors (CCS) will suffer from chronic disease. We compared adherence to national dietary recommendations between CCS, their siblings and the Swiss population, identified determinants of adherence, and assessed the association of adherence with cardiovascular disease (CVD) risk profiles. Methods: As part of the Swiss Childhood Cancer Survivor Study (SCCSS), a questionnaire was sent to all Swiss resident CCS aged <21 years at diagnosis, who survived ≥5 years and were 16–45 years old at the time of the survey. We compared dietary adherence between CCS, their siblings and participants in
SUN-P080 CHANGE IN BODY COMPOSITION AND NUTRIENT INTAKE AFTER CHEMOTHERAPY TREATMENT OF BREAST CANCER PATIENTS E. Chae1, J. Baek 1, M. Rha1, Y. Cho1. 1Clinical Nutrition Part, Samsung Medical Center, Gangnam-gu, Seoul, Republic of Korea Rationale: The aim of this study was to investigate the changes in weight, body composition and nutrient intake after adjuvant chemotherapy treatment of breast cancer patients. Methods: Analyses of outcomes was conducted on 111 subjects with nutrition counseling after chemotherapy between March and May 2010 among breast patients with nutrition counseling before adjuvant chemotherapy. The anthropometric and biochemical data, nutrient intake were measured before and after chemotherapy treatment. All data were analyzed using PASW 18.0 with a significance of 95%. Results: The result of the study indicated that the body weight was not changed between before and after chemotherapy treatment, despite the tendency of weight gain after treatment. However, the body composition significantly changed, with a mean loss of 0.53 kg fat free mass (38.89 ± 3.78 kg vs 38.36 ± 3.78 kg, p < 0.05). Especially, within 6 months after the end of treatment, the patients showed highly significant change in body composition, with a mean loss of 0.34 kg FFM and a mean 2.1% increase in percent body fat, from 29.25 ± 4.79% to 31.32 ± 4.57% ( p < 0.05). Energy intake was not significantly changed after adjuvant chemotherapy treatment (1621.34 ± 376.35 kcal vs 1566.45 ± 319.14 kcal), whereas protein intake was significantly decreased after the chemotherapy treatment (61.04 ± 20.45 g vs 55.4 ± 16.24 g, p < 0.05). On the other hand, increased intake of cereals and oils group comprised significant percent of total calorie intake. Conclusion: This study showed unfavorable changes in body composition without weight change for breast cancer patients receiving adjuvant chemotherapy treatment whereas protein intake was significantly decreased. Taken together, it is necessary to counsel in the nutritional aspect as soon as possible, to minimize the change in body composition after chemotherapy. Disclosure of Interest: None declared
SUN-P081 THE INFLUENCE OF ADIPOSE TISSUE-SECRETED FACTORS ON THE PROGRESSION OF MALNUTRITION OF ONCOLOGICAL PATIENTS - PRELIMINARY RESULTS E. Sobczak1,2, S. Małgorzewicz1, W. J. Kruszewski2,3. 1 Department of Clinical Nutrition and Dietetics, Medical University of Gdańsk, Gdańsk, 2Department of Surgical Oncology, Gdynia Oncology Centre, Gdynia, 3Department of Oncology Propedeutics, Medical University of Gdańsk, Gdańsk, Poland Rationale: Malnutrition in patients with gastrointestinal cancer is mainly associated with muscle mass reduction. However,
Poster research shows that fat loss occurs even more rapidly and to a greater extent than loss of muscle tissue. Better understanding of the complex role of adipose tissue in development of cancer related malnutrition may be crucial for the development of cancer cachexia-specific markers and methods of its treatment. Methods: We present the preliminary results of a study conducted on 63 gastrointestinal adenocarcinoma patients and 20 from control group. Median age of 66.4 and median BMI 25.37 ± 4.7. The nutritional status was screened with NRS 2002, apetite with SNAQ and performance status with Karnofsky Scale. Samples collected from visceral adipose tissue for the future measurements of concentrations of selected hormones and inflammatory markers. The biochemical tests were tested before the procedure. Statistical analysis with Spearman rank correlation was performed. Results: The preliminary results indicate a statistically significant correlation between the presence and the severity of gastrointestinal adenocarcinoma and the nutritional status recorded by NRS 2002 (r = 0.62), BMI (r = −0.27), Karnofsky Scale (r = −0.52) and apetite (r = −0.59). There also was a statistically significant correlation between the size of tumour (T) and the nutritional status recorded by NRS 2002 (r = 0.41), BMI (r = −0.31), apetite(r = −0.42) and Karnofsky scale (r = −0.49). Similiar results were obtained when comparing the presence and number of metastases to the lymph nodes and distant metastases. The median albumin concentration in the examined group was 36.23 ± 11.47 g/L. Conclusion: The preliminary results indicate a correlation between the degree of malnutrition (NRS 2002, SGA), BMI, apetite and Karnofsky scale and the presence and the severity of gastrointestinal adenocarinoma. Disclosure of Interest: None declared
SUN-P082 LOW ADHERENCE TO DIETARY RECOMMENDATIONS IN ADULT CHILDHOOD CANCER SURVIVORS F. N. Belle1,2, L. Wengenroth3, A. Weiss1, G. Sommer1, M. Beck Popovic4, M. Ansari5, M. Bochud2, C. E. Kuehni1, on behalf of the Swiss Paediatric Oncology Group (SPOG). 1Institute of Social and Preventive Medicine, University of Bern, Bern, 2 Division of Chronic Diseases, Institute of Social and Preventive Medicine, Lausanne University Hospital CHUV, Lausanne, Switzerland; 3Institute of Occupational, Social and Environmental Medicine, Ludwig-Maximilians-Universtität, Munich, Germany; 4Paediatric Haematology-Oncology Unit, Lausanne University Hospital CHUV, Lausanne, 5Department of Paediatrics, Onco-Haematology Unit, Geneva University Hospital HUG, Geneva, Switzerland Rationale: Poor diet may increase the risk that childhood cancer survivors (CCS) will suffer from chronic disease. We compared adherence to national dietary recommendations between CCS, their siblings and the Swiss population, identified determinants of adherence, and assessed the association of adherence with cardiovascular disease (CVD) risk profiles. Methods: As part of the Swiss Childhood Cancer Survivor Study (SCCSS), a questionnaire was sent to all Swiss resident CCS aged <21 years at diagnosis, who survived ≥5 years and were 16–45 years old at the time of the survey. We compared dietary adherence between CCS, their siblings and participants in