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SUN-P100: Randomized, Controlled Trial on the Effect of Maltodextrin on Training Efficiency in Stroke Rehabilitation
Nutrition and chronic diseases 1 Conclusion: In fact, where the cardiac patient is or may be a patient with special needs within the nephrological service specific enteral therapies, in both cases, the conservative treatment and the replenishment continues renal or flashing may favor the maintenance of nutritional status of the patient and the reduction of the consequences of renocárdica syndrome. In population studies, be hospitalized for compensation is an indicator of greater severity and worse prognosis. Disclosure of Interest: None declared
SUN-P099 ASSOCIATION THE CHRONIC KIDNEY DISEASE (CKD) AND CHANGES IN CARDIOVASCULAR RISK FACTORS IN PATIENTS FROM NUTRITION SERVICE F. C. Amparo1, D. Magnoni1, K. Gama1, A. Monteiro1, P. Moreira1, C. Paiva1, R. Alves1, C. Kovacs1. 1Nutrition, Dante Pazzanese Institute of Cardiology, Sao Paulo, Brazil Rationale: One reason for this strong association is due to risk factors atherogenic classic for cardiovascular disease (CVD) such as blood pressure, diabetes mellitus, obesity, dyslipidemia, which contribute a pathogenesis for progressive loss of renal function. The objective of this study was to investigate the association of cardiovascular risk factors with CKD in these patients. Methods: Transversal cohort study evaluated 42 patients in stage 3–5 CKD, [66 (38–90) years, 76.2% men]. The following risk factors were considered: obesity, lipid profile, diabetes, microalbuminuria and blood pressure. For statistical analysis, the chi-square test was used for association between quantitative variables was applied to the linear correlation coefficient of Pearson’s, with a significance level of 5% ( p < 0.05). Results: The glomerular filtration rate (GFR) was negatively correlated with urea (r = −0.56; p < 0.01) and HDL (r = −0.28, p = 0.07). Urea is a weak predictor of GFR (alone) about 40– 70% return plasma via passive diffusion process. Microalbuminuria was positively correlated with TG (r = 0.56; p = 0.05). Increased triglycerides are associated with changes in clearance and subsequent increase in plasma levels. Blood glucose was positively correlated with HDL (r = 0.34; p = 0.04) and urea (r = 0.33; p = 0.06). DM is directly associated with uremia, since it is of the main factors of development of CKD. We note that some parameters showed a trend for significance, this is the sample number. The evaluated patients were using medications such as statins, oral hypoglycemic agents and antihypertensives. Therefore, the correlations were not statistically significant, as these patients were already treated. Conclusion: Concluded that in patients with CKD undergoing conservative treatment, treated with medications, nutritional monitoring is important to prevent disease progression and cardiovascular outcomes. Disclosure of Interest: None declared
SUN-P100 RANDOMIZED, CONTROLLED TRIAL ON THE EFFECT OF MALTODEXTRIN ON TRAINING EFFICIENCY IN STROKE REHABILITATION D. M. Nissen1, M. R. Jakobsen1, H. K. Iversen2, M. Warzecha2, J. R. Andersen1. 1Department of Nutrition, Exercise and Sports, University of Copenhagen, 2Department of Neurology, Rigshospitalet Glostrup, Copenhagen, Denmark
S81 Rationale: Patients in rehabilitation after stroke often experience fatigue during exercise probably due to reduced glycogen stores during workout. The consequence in clinical practice is often decreased exercise intensity and duration. The aim was to investigate whether a supplement of maltodextrin during and after exercise can improve the efficiency of the training programme. Methods: Randomized, controlled, double-blinded trial. Stroke patients in the rehabilitation program receive either supplementary maltodextrin (male = 2 × 15 g, female = 2 × 10 g) mixed in 100 mL of lemonade before and after workouts (intervention. n = 21) or 100 mL lemonade before and after workouts (control, n = 20) for 2 weeks or untill training stopped for medical reasons. Primary endpoints included: duration of workouts with physiotherapist and intensity of exercise measured by the physiotherapist on a Borg-Scale. Secondary endpoints included: experienced fatigue (5-point scale), MAS (Motor Assessment Scale), 10MWT (10 meter walk test) and RSS (rise and sit test). Diets were identical in the groups and were the normal routine of the department. Results: By Intention-To-Treat analysis showed no significant differences on the primary endpoints, but significantly better results in the intervention group on all secondary endpoints. The intervention group felt more energetic and less sleepy, drowsy and worn out after exercise and less fatigued before workout than the control group. No cases of elevated blood glucose was observed. Conclusion: The results seem promissing, but the dose of maltodextrin was probably too low, and a high carbohydrate content in basic the diet could be potentielly beneficial. Disclosure of Interest: None declared
SUN-P101 SARCOPENIA AND DYNAPENIA IN PATIENTS WITH PARKINSONISM M. Barichella1, G. Pinelli1, L. Iorio1, E. Cassani1, A. Valentino1, C. Pusani1, V. Ferri1, C. Bolliri1, M. Pasqua1, G. Pezzoli1, G. Frazzitta2, E. Cereda3. 1Parkinson Institute, ASST G. Pini-CTO, ex ICP, Milano, 2Department of Brain Injury and Parkinson Disease Rehabilitation, “Moriggia-Pelascini” Hospital, Como, 3Fondazione IRCCS Policlinico San Matteo, Pavia, Italy Rationale: To estimate prevalence of sarcopenia and dynapenia in Parkinson’s disease (PD) outpatients and to investigate their association with the features of the disease. Methods: Consecutive patients (N = 364) aged ≥65 years, affected by parkinsonian syndromes and attending a specialised tertiary care centre were included. Skeletal muscle mass (SMM), as well as strength and gait speed (GS) were assessed by bioimpedence analysis, handgrip dynamometry, and the 4-meter walking test, respectively. Based on these assessments sarcopenia was diagnosed using the EWGSOP criteria. Dynapenia was defined as handgrip strength <30 kg and <20 kg in men and women, respectively. Results: In total, 235 patients (64.6%) had a diagnosis of idiopathic PD. Low SMM index was recorded in 27 patients. Due to gait disturbances and postural instability, GS could not be measured in 98 patients and was found to be reduced in 61.3% of those assessed. Prevalence of sarcopenia and
SUN-P099 ASSOCIATION THE CHRONIC KIDNEY DISEASE (CKD) AND CHANGES IN CARDIOVASCULAR RISK FACTORS IN PATIENTS FROM NUTRITION SERVICE F. C. Amparo1, D. Magnoni1, K. Gama1, A. Monteiro1, P. Moreira1, C. Paiva1, R. Alves1, C. Kovacs1. 1Nutrition, Dante Pazzanese Institute of Cardiology, Sao Paulo, Brazil Rationale: One reason for this strong association is due to risk factors atherogenic classic for cardiovascular disease (CVD) such as blood pressure, diabetes mellitus, obesity, dyslipidemia, which contribute a pathogenesis for progressive loss of renal function. The objective of this study was to investigate the association of cardiovascular risk factors with CKD in these patients. Methods: Transversal cohort study evaluated 42 patients in stage 3–5 CKD, [66 (38–90) years, 76.2% men]. The following risk factors were considered: obesity, lipid profile, diabetes, microalbuminuria and blood pressure. For statistical analysis, the chi-square test was used for association between quantitative variables was applied to the linear correlation coefficient of Pearson’s, with a significance level of 5% ( p < 0.05). Results: The glomerular filtration rate (GFR) was negatively correlated with urea (r = −0.56; p < 0.01) and HDL (r = −0.28, p = 0.07). Urea is a weak predictor of GFR (alone) about 40– 70% return plasma via passive diffusion process. Microalbuminuria was positively correlated with TG (r = 0.56; p = 0.05). Increased triglycerides are associated with changes in clearance and subsequent increase in plasma levels. Blood glucose was positively correlated with HDL (r = 0.34; p = 0.04) and urea (r = 0.33; p = 0.06). DM is directly associated with uremia, since it is of the main factors of development of CKD. We note that some parameters showed a trend for significance, this is the sample number. The evaluated patients were using medications such as statins, oral hypoglycemic agents and antihypertensives. Therefore, the correlations were not statistically significant, as these patients were already treated. Conclusion: Concluded that in patients with CKD undergoing conservative treatment, treated with medications, nutritional monitoring is important to prevent disease progression and cardiovascular outcomes. Disclosure of Interest: None declared
SUN-P100 RANDOMIZED, CONTROLLED TRIAL ON THE EFFECT OF MALTODEXTRIN ON TRAINING EFFICIENCY IN STROKE REHABILITATION D. M. Nissen1, M. R. Jakobsen1, H. K. Iversen2, M. Warzecha2, J. R. Andersen1. 1Department of Nutrition, Exercise and Sports, University of Copenhagen, 2Department of Neurology, Rigshospitalet Glostrup, Copenhagen, Denmark
S81 Rationale: Patients in rehabilitation after stroke often experience fatigue during exercise probably due to reduced glycogen stores during workout. The consequence in clinical practice is often decreased exercise intensity and duration. The aim was to investigate whether a supplement of maltodextrin during and after exercise can improve the efficiency of the training programme. Methods: Randomized, controlled, double-blinded trial. Stroke patients in the rehabilitation program receive either supplementary maltodextrin (male = 2 × 15 g, female = 2 × 10 g) mixed in 100 mL of lemonade before and after workouts (intervention. n = 21) or 100 mL lemonade before and after workouts (control, n = 20) for 2 weeks or untill training stopped for medical reasons. Primary endpoints included: duration of workouts with physiotherapist and intensity of exercise measured by the physiotherapist on a Borg-Scale. Secondary endpoints included: experienced fatigue (5-point scale), MAS (Motor Assessment Scale), 10MWT (10 meter walk test) and RSS (rise and sit test). Diets were identical in the groups and were the normal routine of the department. Results: By Intention-To-Treat analysis showed no significant differences on the primary endpoints, but significantly better results in the intervention group on all secondary endpoints. The intervention group felt more energetic and less sleepy, drowsy and worn out after exercise and less fatigued before workout than the control group. No cases of elevated blood glucose was observed. Conclusion: The results seem promissing, but the dose of maltodextrin was probably too low, and a high carbohydrate content in basic the diet could be potentielly beneficial. Disclosure of Interest: None declared
SUN-P101 SARCOPENIA AND DYNAPENIA IN PATIENTS WITH PARKINSONISM M. Barichella1, G. Pinelli1, L. Iorio1, E. Cassani1, A. Valentino1, C. Pusani1, V. Ferri1, C. Bolliri1, M. Pasqua1, G. Pezzoli1, G. Frazzitta2, E. Cereda3. 1Parkinson Institute, ASST G. Pini-CTO, ex ICP, Milano, 2Department of Brain Injury and Parkinson Disease Rehabilitation, “Moriggia-Pelascini” Hospital, Como, 3Fondazione IRCCS Policlinico San Matteo, Pavia, Italy Rationale: To estimate prevalence of sarcopenia and dynapenia in Parkinson’s disease (PD) outpatients and to investigate their association with the features of the disease. Methods: Consecutive patients (N = 364) aged ≥65 years, affected by parkinsonian syndromes and attending a specialised tertiary care centre were included. Skeletal muscle mass (SMM), as well as strength and gait speed (GS) were assessed by bioimpedence analysis, handgrip dynamometry, and the 4-meter walking test, respectively. Based on these assessments sarcopenia was diagnosed using the EWGSOP criteria. Dynapenia was defined as handgrip strength <30 kg and <20 kg in men and women, respectively. Results: In total, 235 patients (64.6%) had a diagnosis of idiopathic PD. Low SMM index was recorded in 27 patients. Due to gait disturbances and postural instability, GS could not be measured in 98 patients and was found to be reduced in 61.3% of those assessed. Prevalence of sarcopenia and