- Email: [email protected]
Support for protein capture
Biosensors & Bioelectronics Vol. 12 No. 2 (1997)
News and Market Update The Section is a snap-shot of what is happening now in the field of biosensors and bioelectronics. Edited from international printed and electronic media, using research, application, novelty and innovation as key words, we give you the pearls!
Measuring the bitter in bitter The bittemess sensation is loca&d at the back of the tongue and the bittemess of beer is derived from the bitter tasting hop iso-alpha acids. The BeerProbe, a rapid in-line beer bittemess and colour analyzer, uses the fluorescente properties of the iso-alpha acids, and the quenching effect produced fiom colour dependent absorption. The fluorescente emission of the beer is measured against known standards enabling accurate in-line value of colour and bittemess to be rapidly obtained. The patented fluorescente technique was developed by Instruments SA (UK) Ltd, a subsidiary of Instruments SA France in conjunction with Whitbread PLC. For jùrther information contact: Chris Kemp, Instruments S.A. (UK) Ltd, 2-4 Wigton Gardens, Stanmore, Mdldesex HA7 IBG, UK, tel: [44/ 181 204 8142, fax: (441181 204 6142, email: [email protected]. uk Inert Coating Applications
for
Critical
Biomedical
Pwlene, a xylylene polymer originally developed as a protective coating for electronic assemblies, is now finding applications in the biomedical field; where it is said to be suitable for coating bone pins and temporary hardware, prosthetic components, catheters, heart pacemakers, cochlea implants, neurological probes and other similar devices. The optically clear, high performance polymer coating is claimed to be pure, highly resistant to body fluids and is compatible with
body tissues. Typically applied in a coating thickness of 5 to 25 micrometers this very thin, transparent protective polymer layer is pinhole fiee, uniform and conf%rmaland can be applied to a wide variety of substrate materials. The coating is stable, causes minima1 or no change in response characteristics and isolates surfaces electrically and chemically from body fluids, moisture and ionic contamination, as wel1 I as offering excellent dry film lubricity. / Forjûrther information contact: Nova Tran Ltd, Monarch Rd, Northampton NN2 6EH, UK, tel: [44] 1604 715600, fax: [44] 1604 715483 IL purchases Mallinckrodt’s Sensors Systems Mallinckrodt’s sensor systems business, having been considered ‘no longer fitting their strategie direction’, has been acquired by the American diagnostics company Instrumentation Laboratory for an undisclosed amount Pharmacia Biosensor becomes Biocore Following a strategie assessment Pharmacia Biosensor have refocused their identity and become more closely identified with their instruments by changing the corporate name to Biocore AB. The Company’saddresses, contacts and contact numbers remain unchanged. Support for Protein Capture The Biosupport Division of Pal1 Corporation has introduced a new solid phase support for use in molecular/immunoassays. The Immunodyne ABC membrane is designed to covalently immobilise polyclonal and monoclonal antibodies, enzymes
i
Biosensors & Bioelectronics Vol. 12 No. 2 (1997)
Considered to be a fairly mature marke& growth is expected primarily in tbe areas of homecare monitors, and portable monitors. The technology trends are towards non-invasive monitoring and when possible, stepdown monitor&, which would in turn imply better and more efficient use of intensive care units. By geographical region, (for 1994) Germany accounted for around 345% of market revenue followed by France, UK and Italy with 16.2%, 13.2% and 12.6% respectively. The remaining 23.5% was accounted for by Benelux (8.2), Iberia (3.6), Scandinavia (5.9), and Rest of Europe (5.8). Though there are more that 50 companies servicing the Ewopean patient monitoring market, Hewlett-Packard in the dominant agent in both the geographical bloc and by individual country. In 1994 H-P had 27% market share more than twice its nearest competitor (Siemens) with 13%. For&rther information on Frost & Sullivan report ‘The European Market for Patient Monitoring Equipment (1975-56) priced at $3,800; contact Kristina Menzefricke @ Frost & Sullivan, Sullivan House, 4 Grosvenor Gardens, London SWl W ODH, UK, tel: 1441 171 915 7824, fax: [44] 171 730 3343
and peptide antigens. The microporous structure of the membrane provides a greater binding capacity that traditional non-porous solid phase surfaces, with an available immobilization area of up to 3OOcm’per cm*. In addition, tbe membrane covalently binds proteins, so that immobilized protein molecules cannot be washed away from its surface. For jùrther information contact: Pal1 Biosupport Division, 25 Harbor Park Drive, Port Washington, NY 11050, USA, tel: [l] 516 484 3600, fax: [IJ 516 484 363 7 European Patient Monitoring Frost & Sulhvan value the total European market for patient monitoring equipment (meaning Stationary electmcardiography units, Stand-alone pulse oximeters, Respiratory gas monitors [comprising of capnographs and multiparameter gas monitors], Intrapartum foetal monitors, and, Stand-akme neonatal transcutaneous monitors and modular neonatal monitors) at $244.4m in 1994. From this base-year the market is predicted to grow to $275. lm in the year 2001- a compound annual growth rate of 1.7% over that time period. By comparison, unit sales wil1 decrease í?om 28,400 (1994) per year to 28,200 (2001); resulting from a market shift from standalone units to multiparameter monitors towards the end of the ccntury.
% Revenue of European Patient Monitoring Equipment Market by Product Type Product Type
1994
2001
Stationary electrocardiography units
60.7
63.8
Stand-alone pulse oximeters
9.8
4.9
Respiratory gas monitors
17.9
19.1
Intrapartum foetal monitors
5.0
5.7
Stand-alone neonatal monitors
6.2
6.4
News and Market Update The Section is a snap-shot of what is happening now in the field of biosensors and bioelectronics. Edited from international printed and electronic media, using research, application, novelty and innovation as key words, we give you the pearls!
Measuring the bitter in bitter The bittemess sensation is loca&d at the back of the tongue and the bittemess of beer is derived from the bitter tasting hop iso-alpha acids. The BeerProbe, a rapid in-line beer bittemess and colour analyzer, uses the fluorescente properties of the iso-alpha acids, and the quenching effect produced fiom colour dependent absorption. The fluorescente emission of the beer is measured against known standards enabling accurate in-line value of colour and bittemess to be rapidly obtained. The patented fluorescente technique was developed by Instruments SA (UK) Ltd, a subsidiary of Instruments SA France in conjunction with Whitbread PLC. For jùrther information contact: Chris Kemp, Instruments S.A. (UK) Ltd, 2-4 Wigton Gardens, Stanmore, Mdldesex HA7 IBG, UK, tel: [44/ 181 204 8142, fax: (441181 204 6142, email: [email protected]. uk Inert Coating Applications
for
Critical
Biomedical
Pwlene, a xylylene polymer originally developed as a protective coating for electronic assemblies, is now finding applications in the biomedical field; where it is said to be suitable for coating bone pins and temporary hardware, prosthetic components, catheters, heart pacemakers, cochlea implants, neurological probes and other similar devices. The optically clear, high performance polymer coating is claimed to be pure, highly resistant to body fluids and is compatible with
body tissues. Typically applied in a coating thickness of 5 to 25 micrometers this very thin, transparent protective polymer layer is pinhole fiee, uniform and conf%rmaland can be applied to a wide variety of substrate materials. The coating is stable, causes minima1 or no change in response characteristics and isolates surfaces electrically and chemically from body fluids, moisture and ionic contamination, as wel1 I as offering excellent dry film lubricity. / Forjûrther information contact: Nova Tran Ltd, Monarch Rd, Northampton NN2 6EH, UK, tel: [44] 1604 715600, fax: [44] 1604 715483 IL purchases Mallinckrodt’s Sensors Systems Mallinckrodt’s sensor systems business, having been considered ‘no longer fitting their strategie direction’, has been acquired by the American diagnostics company Instrumentation Laboratory for an undisclosed amount Pharmacia Biosensor becomes Biocore Following a strategie assessment Pharmacia Biosensor have refocused their identity and become more closely identified with their instruments by changing the corporate name to Biocore AB. The Company’saddresses, contacts and contact numbers remain unchanged. Support for Protein Capture The Biosupport Division of Pal1 Corporation has introduced a new solid phase support for use in molecular/immunoassays. The Immunodyne ABC membrane is designed to covalently immobilise polyclonal and monoclonal antibodies, enzymes
i
Biosensors & Bioelectronics Vol. 12 No. 2 (1997)
Considered to be a fairly mature marke& growth is expected primarily in tbe areas of homecare monitors, and portable monitors. The technology trends are towards non-invasive monitoring and when possible, stepdown monitor&, which would in turn imply better and more efficient use of intensive care units. By geographical region, (for 1994) Germany accounted for around 345% of market revenue followed by France, UK and Italy with 16.2%, 13.2% and 12.6% respectively. The remaining 23.5% was accounted for by Benelux (8.2), Iberia (3.6), Scandinavia (5.9), and Rest of Europe (5.8). Though there are more that 50 companies servicing the Ewopean patient monitoring market, Hewlett-Packard in the dominant agent in both the geographical bloc and by individual country. In 1994 H-P had 27% market share more than twice its nearest competitor (Siemens) with 13%. For&rther information on Frost & Sullivan report ‘The European Market for Patient Monitoring Equipment (1975-56) priced at $3,800; contact Kristina Menzefricke @ Frost & Sullivan, Sullivan House, 4 Grosvenor Gardens, London SWl W ODH, UK, tel: 1441 171 915 7824, fax: [44] 171 730 3343
and peptide antigens. The microporous structure of the membrane provides a greater binding capacity that traditional non-porous solid phase surfaces, with an available immobilization area of up to 3OOcm’per cm*. In addition, tbe membrane covalently binds proteins, so that immobilized protein molecules cannot be washed away from its surface. For jùrther information contact: Pal1 Biosupport Division, 25 Harbor Park Drive, Port Washington, NY 11050, USA, tel: [l] 516 484 3600, fax: [IJ 516 484 363 7 European Patient Monitoring Frost & Sulhvan value the total European market for patient monitoring equipment (meaning Stationary electmcardiography units, Stand-alone pulse oximeters, Respiratory gas monitors [comprising of capnographs and multiparameter gas monitors], Intrapartum foetal monitors, and, Stand-akme neonatal transcutaneous monitors and modular neonatal monitors) at $244.4m in 1994. From this base-year the market is predicted to grow to $275. lm in the year 2001- a compound annual growth rate of 1.7% over that time period. By comparison, unit sales wil1 decrease í?om 28,400 (1994) per year to 28,200 (2001); resulting from a market shift from standalone units to multiparameter monitors towards the end of the ccntury.
% Revenue of European Patient Monitoring Equipment Market by Product Type Product Type
1994
2001
Stationary electrocardiography units
60.7
63.8
Stand-alone pulse oximeters
9.8
4.9
Respiratory gas monitors
17.9
19.1
Intrapartum foetal monitors
5.0
5.7
Stand-alone neonatal monitors
6.2
6.4