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Surgical Resection of Mandible as Treatment for Central Giant Cell Lesion: Clinical Case Report
ORAL AND MAXILLOFACIAL PATHOLOGY e56 Abstracts syndactyly; maxillary retrusion; anterior open bite; posterior crossbite; Byzantine-arch palate; multiple dental anomalies of position (maxillary dental crowding and dental rotation) and shape (pronounced enamel bridge in lateral incisors and taurodontism in all second molar teeth); and bilateral elongation of the styloid process. Her parents were young adults and her mother had used illicit drugs and alcohol during pregnancy. The patient is undergoing treatment by her orthodontist. This rare case of taurodontism in a patient with Apert syndrome expands knowledge of the possible abnormalities associated with this pathological condition and underscores the role of nonspecific genetic pathways involved in syndromic taurodontism.
PCC-161 - SURGICAL RESECTION OF MANDIBLE AS TREATMENT FOR CENTRAL GIANT CELL LESION: CLINICAL CASE REPORT. ISRAEL ALEXANDRE DE ARAUJO SENA, ISABELA PINHEIRO CAVALCANTI LIMA, ROBERTO TIAGO ALVES PINHEIRO, ROSEANA DE ALMEIDA FREITAS, LELIA BATISTA DE SOUZA, BRUNA RAFAELA MARTINS DOS SANTOS. UNIVERSIDADE DO ESTADO DO RIO GRANDE DO NORTE. Central giant cell lesion (CGCL) is an uncommon intraosseous benign lesion of unknown etiology, the prevalence of which is highest among females in the third decade of life. It most often occurs in the jaw. The clinical behavior of CGCL is variable, ranging from an asymptomatic volume increase to an aggressive symptomatic lesion with bone destruction. A 46-yearold male sought dental care complaining of a volume increase, in the right mandibular region, that had first appeared 2 years earlier. Panoramic radiography and computed tomography indicated a diagnosis of solid ameloblastoma. Analysis of an incisional biopsy sample indicated a CGCL. As a definitive therapy, we performed en bloc surgical resection with partial removal of the mandible and reconstruction with a 2.4-mm plate. The patient returned periodically for evaluation, and the treatment was found to be satisfactory, there having been no relapses during the first year of follow-up.
PCC-162 - CONTACT STOMATITIS TO TOOTHPASTE: IMPORTANCE OF DIFFERENTIAL DIAGNOSIS. SIMONE DE MACEDO AMARAL, ÁGUIDA MARIA MENEZES AGUIAR MIRANDA, JULIANA DE NORONHA SANTOS NETTO, FÁBIO RAMOA PIRES. UNIVERSIDADE ESTÁCIO DE SÁ/ASSOCIAÇÃO BRASILEIRA DE ODONTOLOGIA e RIO DE JANEIRO. Oral contact reactions are common in oral medicine daily practice, and the differential diagnosis can be challenging. Here, we report 2 cases of contact stomatitis. A 48-year-old female presented for consultation with several painful whitish, small plaques on the floor of the mouth that started just after initiating the use of a new toothpaste (Oral B ProSaúdeÒ). Due to the association of the symptoms, use of the toothpaste was interrupted and the lesions disappeared in 5 days. In the second case, a 67-year-old female was referred for evaluation of reddish plaques on the anterior ventral and right lateral border of the tongue and lower labial mucosa. The lesions started after beginning the use of a new toothpaste (Oral B ProSaúdeÒ). Discontinuation of its use resulted in complete remission of the lesions within 7 days. Clinicians should be aware of oral local contact stomatitis, and it is essential to consider toothpastes and other oral hygiene products as possible triggers.
OOOO August 2015 PCC-163 - DIRECT IMMUNOFLUORESCENCE AS AN IMPORTANT TOOL IN THE DIAGNOSIS OF PEMPHIGUS VULGARIS CONFINED TO THE ORAL CAVITY. AMANDA LAÍSA DE OLIVEIRA LIMA, MARIA LETÍCIA CINTRA, CAMILA GUEDES RAMOS, FRANCIELLE SANTOS NASCIMENTO, FERNANDA BRAGA PEIXOTO, SONIA MARIA SOARES FERREIRA, CAMILA MARIA BEDER RIBEIRO. CENTRO UNIVERSITÁRIO CESMAC. Mucocutaneous diseases can remain restricted to the mouth for decades, impairing the nosological diagnosis. A 55-year-old patient presented to our outpatient dental care center complaining of having had intermittent painful sores in the gingiva and oral mucous membranes for approximately 15 years. On clinical examination, the following differential diagnoses were proposed: pemphigus vulgaris (PV), bullous pemphigoid, and other autoimmune diseases. Two perilesional biopsies of the buccal mucosa were performed, and the histopathological examination revealed tiny intraepithelial suprabasal clefts. Direct immunofluorescence (DIF) showed strong linear deposits of immunoglobulin G and C3 in the intercellular space of the stratum spinous, establishing the diagnosis of PV. The use of histopathology and DIF can be of great value in the approach to PV patients, whose lesions remain restricted to the oral cavity for long periods of time.
PCC-164 - ORAL FOLLICULAR LYMPHOID HYPERPLASIA: A CASE REPORT FOCUSING ON ITS DIFFERENTIAL DIAGNOSIS. MARIELE SILVA DE AZEVEDO, THAYRONE IRINEU DA COSTA, FRANCISCO DAS CHAGAS MARISON ALVES, GIORDANO BRUNO DE ARAÚJO, ANA BEATRIZ RODRIGUES DA MOTA, MARIA AUXILIADORA CARVALHO DA ROCHA, JOABE DOS SANTOS PEREIRA. UNIVERSIDADE ESTADUAL DA PARAÍBA/UNIVERSIDADE FEDERAL DO RIO GRANDE DO NORTE. Follicular lymphoid hyperplasia is an uncommon, poorly understood, non-neoplastic lymphoproliferative disease. This entity can be clinically and histologically confused with malignant lymphoma. A 76-year-old male presented with an elevated mass on the right lateral border of the tongue. The lesion, which was 1 cm in diameter, had appeared 8 months earlier. The patient reported no history of local trauma. There were no secondary signs or lymphadenopathy. The diagnostic hypothesis was blastoma. Histopathological examination revealed a dense lymphoid infiltrate with several lymphoid follicles and germinal centers, a thick mantle zone of small mature lymphocytes, tingible body macrophages, and a polymorphic lymphoid cell population. A final diagnosis of follicular lymphoid hyperplasia was made. In some cases, indistinct histological features contribute to the misdiagnosis of lymphoma, with consequent unnecessary treatment. In such cases, immunohistochemical analysis and molecular studies are essential to achieving an accurate diagnosis.
PCC-165 - ORAL LICHEN PLANUS CLINICAL FEATURES CHANGED BY CANDIDIASIS INFECTION. JULIANA TRISTÃO WERNECK, CHRISTIAN STIBICH, TAIARA OLIVEIRA, ELIANE PEDRA DIAS, ARLEY SILVA JUNIOR. UNIVERSIDADE FEDERAL FLUMINENSE. Oral lichen planus (OLP) lesions manifest in different patterns. Erosive OLP can cause pain, itching, and burning. The clinical profile of OLP can change when associated with Candida sp. infection. We present 2 cases in which infection with
PCC-161 - SURGICAL RESECTION OF MANDIBLE AS TREATMENT FOR CENTRAL GIANT CELL LESION: CLINICAL CASE REPORT. ISRAEL ALEXANDRE DE ARAUJO SENA, ISABELA PINHEIRO CAVALCANTI LIMA, ROBERTO TIAGO ALVES PINHEIRO, ROSEANA DE ALMEIDA FREITAS, LELIA BATISTA DE SOUZA, BRUNA RAFAELA MARTINS DOS SANTOS. UNIVERSIDADE DO ESTADO DO RIO GRANDE DO NORTE. Central giant cell lesion (CGCL) is an uncommon intraosseous benign lesion of unknown etiology, the prevalence of which is highest among females in the third decade of life. It most often occurs in the jaw. The clinical behavior of CGCL is variable, ranging from an asymptomatic volume increase to an aggressive symptomatic lesion with bone destruction. A 46-yearold male sought dental care complaining of a volume increase, in the right mandibular region, that had first appeared 2 years earlier. Panoramic radiography and computed tomography indicated a diagnosis of solid ameloblastoma. Analysis of an incisional biopsy sample indicated a CGCL. As a definitive therapy, we performed en bloc surgical resection with partial removal of the mandible and reconstruction with a 2.4-mm plate. The patient returned periodically for evaluation, and the treatment was found to be satisfactory, there having been no relapses during the first year of follow-up.
PCC-162 - CONTACT STOMATITIS TO TOOTHPASTE: IMPORTANCE OF DIFFERENTIAL DIAGNOSIS. SIMONE DE MACEDO AMARAL, ÁGUIDA MARIA MENEZES AGUIAR MIRANDA, JULIANA DE NORONHA SANTOS NETTO, FÁBIO RAMOA PIRES. UNIVERSIDADE ESTÁCIO DE SÁ/ASSOCIAÇÃO BRASILEIRA DE ODONTOLOGIA e RIO DE JANEIRO. Oral contact reactions are common in oral medicine daily practice, and the differential diagnosis can be challenging. Here, we report 2 cases of contact stomatitis. A 48-year-old female presented for consultation with several painful whitish, small plaques on the floor of the mouth that started just after initiating the use of a new toothpaste (Oral B ProSaúdeÒ). Due to the association of the symptoms, use of the toothpaste was interrupted and the lesions disappeared in 5 days. In the second case, a 67-year-old female was referred for evaluation of reddish plaques on the anterior ventral and right lateral border of the tongue and lower labial mucosa. The lesions started after beginning the use of a new toothpaste (Oral B ProSaúdeÒ). Discontinuation of its use resulted in complete remission of the lesions within 7 days. Clinicians should be aware of oral local contact stomatitis, and it is essential to consider toothpastes and other oral hygiene products as possible triggers.
OOOO August 2015 PCC-163 - DIRECT IMMUNOFLUORESCENCE AS AN IMPORTANT TOOL IN THE DIAGNOSIS OF PEMPHIGUS VULGARIS CONFINED TO THE ORAL CAVITY. AMANDA LAÍSA DE OLIVEIRA LIMA, MARIA LETÍCIA CINTRA, CAMILA GUEDES RAMOS, FRANCIELLE SANTOS NASCIMENTO, FERNANDA BRAGA PEIXOTO, SONIA MARIA SOARES FERREIRA, CAMILA MARIA BEDER RIBEIRO. CENTRO UNIVERSITÁRIO CESMAC. Mucocutaneous diseases can remain restricted to the mouth for decades, impairing the nosological diagnosis. A 55-year-old patient presented to our outpatient dental care center complaining of having had intermittent painful sores in the gingiva and oral mucous membranes for approximately 15 years. On clinical examination, the following differential diagnoses were proposed: pemphigus vulgaris (PV), bullous pemphigoid, and other autoimmune diseases. Two perilesional biopsies of the buccal mucosa were performed, and the histopathological examination revealed tiny intraepithelial suprabasal clefts. Direct immunofluorescence (DIF) showed strong linear deposits of immunoglobulin G and C3 in the intercellular space of the stratum spinous, establishing the diagnosis of PV. The use of histopathology and DIF can be of great value in the approach to PV patients, whose lesions remain restricted to the oral cavity for long periods of time.
PCC-164 - ORAL FOLLICULAR LYMPHOID HYPERPLASIA: A CASE REPORT FOCUSING ON ITS DIFFERENTIAL DIAGNOSIS. MARIELE SILVA DE AZEVEDO, THAYRONE IRINEU DA COSTA, FRANCISCO DAS CHAGAS MARISON ALVES, GIORDANO BRUNO DE ARAÚJO, ANA BEATRIZ RODRIGUES DA MOTA, MARIA AUXILIADORA CARVALHO DA ROCHA, JOABE DOS SANTOS PEREIRA. UNIVERSIDADE ESTADUAL DA PARAÍBA/UNIVERSIDADE FEDERAL DO RIO GRANDE DO NORTE. Follicular lymphoid hyperplasia is an uncommon, poorly understood, non-neoplastic lymphoproliferative disease. This entity can be clinically and histologically confused with malignant lymphoma. A 76-year-old male presented with an elevated mass on the right lateral border of the tongue. The lesion, which was 1 cm in diameter, had appeared 8 months earlier. The patient reported no history of local trauma. There were no secondary signs or lymphadenopathy. The diagnostic hypothesis was blastoma. Histopathological examination revealed a dense lymphoid infiltrate with several lymphoid follicles and germinal centers, a thick mantle zone of small mature lymphocytes, tingible body macrophages, and a polymorphic lymphoid cell population. A final diagnosis of follicular lymphoid hyperplasia was made. In some cases, indistinct histological features contribute to the misdiagnosis of lymphoma, with consequent unnecessary treatment. In such cases, immunohistochemical analysis and molecular studies are essential to achieving an accurate diagnosis.
PCC-165 - ORAL LICHEN PLANUS CLINICAL FEATURES CHANGED BY CANDIDIASIS INFECTION. JULIANA TRISTÃO WERNECK, CHRISTIAN STIBICH, TAIARA OLIVEIRA, ELIANE PEDRA DIAS, ARLEY SILVA JUNIOR. UNIVERSIDADE FEDERAL FLUMINENSE. Oral lichen planus (OLP) lesions manifest in different patterns. Erosive OLP can cause pain, itching, and burning. The clinical profile of OLP can change when associated with Candida sp. infection. We present 2 cases in which infection with