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SYNCHRONIC TONGUE SQUAMOUS CELL CARCINOMAS IN YOUNG SIBLINGS
ABSTRACTS
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SYNCHRONIC TONGUE SQUAMOUS CELL CARCINOMAS IN YOUNG SIBLINGS. FIGUEIRA, SAYGO TOMO, JESSICA ARAUJO RENATA CALLESTINI, MARCELO MACEDO CRIVELINI, EDER RICARDO BIASOLI, GLAUCO ISSAMU MIYAHARA and, DANIEL GALERA BERNABE A 30-year-old female patient was referred because of a tongue lesion with 3 months of evolution. Clinical oral examination revealed painful infiltrative ulcer in tongue dorsum measuring 3 £ 2 cm with necrotic areas and well-defined limits. Biopsy was performed, and the histopathologic diagnosis was squamous cell carcinoma (SCC). The patient with clinical stage IV (T4aN1M0) cancer was treated with chemotherapy (CT) followed by partial glossectomy associated with unilateral supraomohyoid cervical emptying besides CT and radiotherapy post surgery. During treatment, her 28-year-old brother noticed a tongue lesion and sought care in our center. Clinical examination revealed a painless ulcer on right lateral tongue border measuring 2 £ 1 cm with well-defined limits and rough surface. The histopathologic diagnosis was also SCC. The clinical stage I (T1N0M0) cancer led to tumor excision with margin control as the treatment. Currently, both siblings are being followed up at our center.
LATE DIAGNOSIS OF INTRAORAL SALI VARY GLAND CARCINOMA. JESSICA ARAUJO FIGUEIRA, LUCAS NOVAES TEIXEIRA, VERA CAVALCANTE DE ARAUJO, CRISTIANE FURUSE, EDER RICARDO BIASOLI, GLAUCO ISSAMU MIYAHARA and, DANIEL GALERA BERNABE A 58-year-old female patient was referred because of a palatal nodular lesion. The patient reported that the lesion began 4 years ago, and she was attended by 5 different dentists without definitive diagnosis. Given its exacerbated growth in the last months, she sought care again, and then she was referred to our center. Clinical oral examination revealed an extensive nodular lesion located on the hard palate measuring 4 £ 3 cm with welldefined limits, smooth surface, and pain with palpation. Our diagnostic hypotheses were pleomorphic adenoma and adenoid cystic carcinoma (ACC). Incisional biopsy was performed, and based on histopathologic and immunohistochemical findings, the diagnosis of ACC was established. Partial maxillectomy and rehabilitation with maxillary obturator prosthesis were performed. Currently, the patient is undergoing dental and psychological care in our center.
CONGENITAL EPULIS: CASE REPORT. KATIANNE SOARES RODRIGUES, ONDINA KARLA MOUSINHO DA SILVA ROCHA, CAIO CESAR DA SILVA BARROS, AFONSO NOBREGA DANTAS, LUIZ ARTHUR BARBOSA DA SILVA, MARINA BOZZINI PAIES and, MARCIA CRISTINA DA COSTA MIGUEL Congenital epulis, also called congenital granular cell lesion, is an uncommon benign soft tissue lesion of unknown etiology that affects the gums of fetuses and neonates. This report describes the case of a 16-day-old female neonate whose lesion was detected at birth. During the intraoral examination, a pink to red staining nodular exophytic lesion was observed with smooth
OOOO January 2020 surface and firm consistency located in the anterior region of the maxillary alveolar ridge. The lesion was submitted to excisional biopsy, and the histopathologic examination revealed the presence of large, rounded cells with abundant granular eosinophilic cytoplasm and basophilic nuclei presenting shapes ranging from round to oval in a richly vascularized fibrous connective tissue stroma. Follow-up was performed after 6 months, and the patient’s mucosa had an aspect of normality.
ADENOMATOID HYPERPLASIA OF THE MINOR SALIVARY GLANDS: CASE REPORT. STHEFANE GOMES FEITOSA, ERASMO BERNARDO MARINHO, KHALIL FERNANDES VIANA, EVELINE TURATTI, FABRICIO DE SOUSA BITU, ROBERTA BARROSO CAVALCANTE and, KARUZA MARIA ALVES PEREIRA Adenomatoid hyperplasia (AH) is a rare nonneoplastic enlargement of minor salivary glands with unknown etiology. The present report describes a case of 57-year-old male patient who presented with complaint of swelling at his right side of posterior hard palate with painful symptomatology. Clinically, the lesion was a nodule covered by healthy mucosa and was of soft consistency. Radiographic examination did not demonstrate any bone involvement. An excisional biopsy was performed, and the specimen sent for microscopic analysis. Histopathologic examination revealed epithelial covering of orthokeratinized stratified squamous type. In the submucosal layer, there were minor salivary gland parenchyma exhibiting hyperplasic, ductal ectasia, and discrete acinar atrophy. The diagnosis was compatible with AH. The patient is under follow-up with no sign of recurrence after 6 months. We emphasize the importance of the correct diagnosis because clinically this lesion can be confused with benign or malignant salivary gland tumors.
PERIPHERAL CALCIFYING EPITHELIAL ODONTOGENIC TUMOR: CASE REPORT. STHEFANE GOMES FEITOSA, NAYANA OLIVEIRA AZEVEDO, JOSE RONILDO LINS DO CARMO FILHO, KARUZA MARIA ALVES PEREIRA, ANA PAULA ^ NEGREIROS NUNES ALVES, PAULO GOBERLANIO DE BARROS SILVA and, MARIO ROGERIO LIMA MOTA Calcifying epithelial odontogenic tumors (CEOTs) are rare benign odontogenic neoplasms of the jaws that account for < 1% of all odontogenic tumors. The peripheral counterpart is an extremely rare lesion that accounts only for 6% of all CEOTs. A 33-year-old woman presented with a mass in the gingiva of the right maxilla. Periapical radiograph showed localized bone loss between teeth 14 and 15. Histopathologic analysis revealed encapsulated lesion with fibrous stroma supporting numerous islands of polyhedral epithelial cells with hyperchromatic nucleus and intercellular bridges. Some of these tumor islands revealed clear cell changes, amorphous eosinophilic deposits, and concentric calcification. The immunohistochemical analysis showed positivity for CK14 in neoplastic cells. The eosinophilic material stained with Congo red exhibited green-apple birefringence under polarized light microscopy. The diagnosis of peripheral CEOT is challenging because of its clinical similarity to other fibrous lesions; therefore, histopathologic examination is essential to elucidate the diagnosis of this neoplasm.
e102
SYNCHRONIC TONGUE SQUAMOUS CELL CARCINOMAS IN YOUNG SIBLINGS. FIGUEIRA, SAYGO TOMO, JESSICA ARAUJO RENATA CALLESTINI, MARCELO MACEDO CRIVELINI, EDER RICARDO BIASOLI, GLAUCO ISSAMU MIYAHARA and, DANIEL GALERA BERNABE A 30-year-old female patient was referred because of a tongue lesion with 3 months of evolution. Clinical oral examination revealed painful infiltrative ulcer in tongue dorsum measuring 3 £ 2 cm with necrotic areas and well-defined limits. Biopsy was performed, and the histopathologic diagnosis was squamous cell carcinoma (SCC). The patient with clinical stage IV (T4aN1M0) cancer was treated with chemotherapy (CT) followed by partial glossectomy associated with unilateral supraomohyoid cervical emptying besides CT and radiotherapy post surgery. During treatment, her 28-year-old brother noticed a tongue lesion and sought care in our center. Clinical examination revealed a painless ulcer on right lateral tongue border measuring 2 £ 1 cm with well-defined limits and rough surface. The histopathologic diagnosis was also SCC. The clinical stage I (T1N0M0) cancer led to tumor excision with margin control as the treatment. Currently, both siblings are being followed up at our center.
LATE DIAGNOSIS OF INTRAORAL SALI VARY GLAND CARCINOMA. JESSICA ARAUJO FIGUEIRA, LUCAS NOVAES TEIXEIRA, VERA CAVALCANTE DE ARAUJO, CRISTIANE FURUSE, EDER RICARDO BIASOLI, GLAUCO ISSAMU MIYAHARA and, DANIEL GALERA BERNABE A 58-year-old female patient was referred because of a palatal nodular lesion. The patient reported that the lesion began 4 years ago, and she was attended by 5 different dentists without definitive diagnosis. Given its exacerbated growth in the last months, she sought care again, and then she was referred to our center. Clinical oral examination revealed an extensive nodular lesion located on the hard palate measuring 4 £ 3 cm with welldefined limits, smooth surface, and pain with palpation. Our diagnostic hypotheses were pleomorphic adenoma and adenoid cystic carcinoma (ACC). Incisional biopsy was performed, and based on histopathologic and immunohistochemical findings, the diagnosis of ACC was established. Partial maxillectomy and rehabilitation with maxillary obturator prosthesis were performed. Currently, the patient is undergoing dental and psychological care in our center.
CONGENITAL EPULIS: CASE REPORT. KATIANNE SOARES RODRIGUES, ONDINA KARLA MOUSINHO DA SILVA ROCHA, CAIO CESAR DA SILVA BARROS, AFONSO NOBREGA DANTAS, LUIZ ARTHUR BARBOSA DA SILVA, MARINA BOZZINI PAIES and, MARCIA CRISTINA DA COSTA MIGUEL Congenital epulis, also called congenital granular cell lesion, is an uncommon benign soft tissue lesion of unknown etiology that affects the gums of fetuses and neonates. This report describes the case of a 16-day-old female neonate whose lesion was detected at birth. During the intraoral examination, a pink to red staining nodular exophytic lesion was observed with smooth
OOOO January 2020 surface and firm consistency located in the anterior region of the maxillary alveolar ridge. The lesion was submitted to excisional biopsy, and the histopathologic examination revealed the presence of large, rounded cells with abundant granular eosinophilic cytoplasm and basophilic nuclei presenting shapes ranging from round to oval in a richly vascularized fibrous connective tissue stroma. Follow-up was performed after 6 months, and the patient’s mucosa had an aspect of normality.
ADENOMATOID HYPERPLASIA OF THE MINOR SALIVARY GLANDS: CASE REPORT. STHEFANE GOMES FEITOSA, ERASMO BERNARDO MARINHO, KHALIL FERNANDES VIANA, EVELINE TURATTI, FABRICIO DE SOUSA BITU, ROBERTA BARROSO CAVALCANTE and, KARUZA MARIA ALVES PEREIRA Adenomatoid hyperplasia (AH) is a rare nonneoplastic enlargement of minor salivary glands with unknown etiology. The present report describes a case of 57-year-old male patient who presented with complaint of swelling at his right side of posterior hard palate with painful symptomatology. Clinically, the lesion was a nodule covered by healthy mucosa and was of soft consistency. Radiographic examination did not demonstrate any bone involvement. An excisional biopsy was performed, and the specimen sent for microscopic analysis. Histopathologic examination revealed epithelial covering of orthokeratinized stratified squamous type. In the submucosal layer, there were minor salivary gland parenchyma exhibiting hyperplasic, ductal ectasia, and discrete acinar atrophy. The diagnosis was compatible with AH. The patient is under follow-up with no sign of recurrence after 6 months. We emphasize the importance of the correct diagnosis because clinically this lesion can be confused with benign or malignant salivary gland tumors.
PERIPHERAL CALCIFYING EPITHELIAL ODONTOGENIC TUMOR: CASE REPORT. STHEFANE GOMES FEITOSA, NAYANA OLIVEIRA AZEVEDO, JOSE RONILDO LINS DO CARMO FILHO, KARUZA MARIA ALVES PEREIRA, ANA PAULA ^ NEGREIROS NUNES ALVES, PAULO GOBERLANIO DE BARROS SILVA and, MARIO ROGERIO LIMA MOTA Calcifying epithelial odontogenic tumors (CEOTs) are rare benign odontogenic neoplasms of the jaws that account for < 1% of all odontogenic tumors. The peripheral counterpart is an extremely rare lesion that accounts only for 6% of all CEOTs. A 33-year-old woman presented with a mass in the gingiva of the right maxilla. Periapical radiograph showed localized bone loss between teeth 14 and 15. Histopathologic analysis revealed encapsulated lesion with fibrous stroma supporting numerous islands of polyhedral epithelial cells with hyperchromatic nucleus and intercellular bridges. Some of these tumor islands revealed clear cell changes, amorphous eosinophilic deposits, and concentric calcification. The immunohistochemical analysis showed positivity for CK14 in neoplastic cells. The eosinophilic material stained with Congo red exhibited green-apple birefringence under polarized light microscopy. The diagnosis of peripheral CEOT is challenging because of its clinical similarity to other fibrous lesions; therefore, histopathologic examination is essential to elucidate the diagnosis of this neoplasm.