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Synchronous Unilateral Parotid Gland Neoplasms of Two Different Histological Types
ORAL AND MAXILLOFACIAL PATHOLOGY e152 Abstracts SYNCHRONOUS UNILATERAL PAROTID GLAND NEOPLASMS OF TWO DIFFERENT HISTOLOGICAL TYPES Tuba Canpolat1, Alper Nabi Erkan2, 1Department of Pathology, Baskent University, Adana, Turkey; 2Department of Otorhinolaryngology, Baskent University, Adana, Turkey The parotid gland is the most usual location of benign neoplasms. The occurrence of multiple tumours in the parotid glands is rare and the majority of these are multifocal Warthin’s tumors. There are many articles about multiple parotid tumors but only a few of them are focused on unilateral synchronous benings tumors. The most common combination is a pleomorphic adenoma and a Warthin’s tumor. We report a 55-year-old female with a basal cell adenoma occurring synchronously with a Warthin’s tumor within the superficial be of her left parotid gland. Keywords: Synchronous, parotid gland neoplasm, unilateral
ANCIENT SCHWANNOMA OF THE PAROTID GLAND: A CASE REPORT Meryem Dogan, Gözde Kir, Fatıma Gürsoy, Ays¸e Nur Ihvan, Department of Pathology, Umraniye Education and Research Hospital, Istanbul, Turkey Ancient schwannoma in the head and neck region is very rare. The tumour occurring in the intraparotid facial nerve is even rarer. In this report, a 37-year-old male patient with an ancient schwannoma of the parotid gland is presented. Grossly masses were 3 2,5 2 and 3 2 2 cm in size. They were well encapsuled and had firm gray white cut surface with hemorrhagic areas. In immunohistochemical study, S 100 protein, vimentin and GFAP was found to be positive. The histological and immunohistochemical examination yielded a diagnosis of ancient schwannoma. Because this is unusual, the case is presented together with the histopathological findings. Keywords: Ancient schwannoma, parotid gland, head and neck
PLEOMORPHIC ADENOMA OF THE LARYNX: CASE REPORT Meryem Dogan, Gözde Kir, Murat Hakan Karabulut, Ays¸e Nur Ihvan, Department of Pathology, Umraniye Education and Research Hospital, Istanbul, Turkey Pleomorphic adenomas are the most common benign neoplasm of the salivary glands. It usually occurs in major salivary glands, such as the parotid and submandibular glands. However, it uncommonly arises from the larynx. These lesions generally present as a slow-growing, painless mass. Malignant transformation of is very rare, but it is increases with time. We report a case of a 59-year-old male who presented with complaints of hoarseness. Examination of the right vertical partial hemilaryngectomy, showed a mucosa-covered, fleshy 2 1.5 1 cm mass in the supraglottic area of larynx. This lesion had histological characteristics of a pleomorphic adenoma, and this was confirmed by immunohistochemical expression of cytokeratin, S-100 protein, GFAP and vimentin. Their histopathological identification is, however, not always straightforward; immunohistochemistry can contribute significantly to the formulation of a definitive diagnosis and to the realization of an appropriate follow-up. Keywords: Pleomorphic adenoma, Larynx, Immunohistochemistry
OOOO March 2015 CALCIFYING EPITHELIAL ODONTOGENIC TUMOR (PINDBORG’S TUMOR): A CASE REPORT Ahmet Mihmanlı1, Emre Aytu gar1, Nihat Demirtas¸2, Suzan Bayer1, 3 1 Fatma Canan Alatlı , Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Bezmialem Vakif University, Istanbul, Turkey; 2Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Bezmialem Vakif University, Istanbul, Turkey; 3Department of Pathology, Faculty of Dentistry, Istanbul University, Istanbul, Turkey Calcifying epithelial odontogenic tumor (CEOT) is a rare benign neoplasm and it has been described by pathologist Jens Jorgen Pindborg in 1955. World Health Organization (WHO) in 2005 classified it as a benign odontogenic tumor, which include odontogenic epithelium with mature, fibrous stroma without odontogenic ectomesenchyme. It is a locally aggressive, painless and slow growing tumor and accounts for less than 1% of all odontogenic tumors. CEOT has high rate of recurrence and generally affects the maxillary posterior region. It occurs between 2nd and 6th decade of life without gender preduection. It is detected by clinical, radiographic and histopathological examination. In general they are associated with an impacted tooth. In this paper we present histopathological and radiological features of a giant CEOT in 42-year-old man. Therefore we aimed to investigate the surgical managements of these tumors. Keywords: Odontogenic tumors, histopathology, calcifying epithelial odontogenic tumor, Pindborg tumor
UNICYSTIC AMELOBLABLASTOMA WITH DIVERSE MURAL PROLIFERATION: A CASE REPORT Emre Barıs¸1, Burcu Sengüven1, Süleyman Bozkaya2, Sara Samur Ergüven2, 1 Department of Oral Pathology, Gazi University Faculty of Dentistry, Ankara, Turkey; 2Department of Oral and Maxillofacial Surgery, Gazi University Faculty of Dentistry, Ankara, Turkey Unicystic ameloblastoma is a benign odontogenic neoplasm which includes several clinic-radiological and histological types. Here we are presenting a case of unicystic ameloblastoma in a 12-year-old boy who complained of swelling on the right mandibular molar region. Radiographic examination revealed a well defined multilocular radiolucent lesion around second molar tooth mimicking dentigerous cyst which was extend to vestibular part of first molar. Following incisional biopsy, a diagnosis of unicystic ameloblastoma was made and marsupialisation was performed for reduced the lesion size. The lesion was totally enucleated 15 months after marsupialisation. Histopathological examination of the enucleation specimen exhibited a unicystic ameloblastoma of luminal, intraluminal, and mural type. Intraluminal proliferation was of plexiform pattern and mural proliferation showed unusual histopathological findings, which revealed follicular, acanthomatous areas coexisted with plexiform areas. 6 months follow up till to date has not revealed any signs of recurrence. Keywords: unicystic ameloblastoma, mural proliferation, diverse histology
WHAT IS THE MEANING OF FOCUS SCORE[1 IN ¨ GREN’S SYNDROME? Leyla Haryullah1, Fulya ÇakaSJO la gao glu1, Demet Etit1, Nes¸e Ekinci1, Emel Civas¸1, Mustafa Özmen2, Gerçek Can2, 1Department of Pathology, Izmir Katip Çelebi University Ataturk Training and Research Hospital,
ANCIENT SCHWANNOMA OF THE PAROTID GLAND: A CASE REPORT Meryem Dogan, Gözde Kir, Fatıma Gürsoy, Ays¸e Nur Ihvan, Department of Pathology, Umraniye Education and Research Hospital, Istanbul, Turkey Ancient schwannoma in the head and neck region is very rare. The tumour occurring in the intraparotid facial nerve is even rarer. In this report, a 37-year-old male patient with an ancient schwannoma of the parotid gland is presented. Grossly masses were 3 2,5 2 and 3 2 2 cm in size. They were well encapsuled and had firm gray white cut surface with hemorrhagic areas. In immunohistochemical study, S 100 protein, vimentin and GFAP was found to be positive. The histological and immunohistochemical examination yielded a diagnosis of ancient schwannoma. Because this is unusual, the case is presented together with the histopathological findings. Keywords: Ancient schwannoma, parotid gland, head and neck
PLEOMORPHIC ADENOMA OF THE LARYNX: CASE REPORT Meryem Dogan, Gözde Kir, Murat Hakan Karabulut, Ays¸e Nur Ihvan, Department of Pathology, Umraniye Education and Research Hospital, Istanbul, Turkey Pleomorphic adenomas are the most common benign neoplasm of the salivary glands. It usually occurs in major salivary glands, such as the parotid and submandibular glands. However, it uncommonly arises from the larynx. These lesions generally present as a slow-growing, painless mass. Malignant transformation of is very rare, but it is increases with time. We report a case of a 59-year-old male who presented with complaints of hoarseness. Examination of the right vertical partial hemilaryngectomy, showed a mucosa-covered, fleshy 2 1.5 1 cm mass in the supraglottic area of larynx. This lesion had histological characteristics of a pleomorphic adenoma, and this was confirmed by immunohistochemical expression of cytokeratin, S-100 protein, GFAP and vimentin. Their histopathological identification is, however, not always straightforward; immunohistochemistry can contribute significantly to the formulation of a definitive diagnosis and to the realization of an appropriate follow-up. Keywords: Pleomorphic adenoma, Larynx, Immunohistochemistry
OOOO March 2015 CALCIFYING EPITHELIAL ODONTOGENIC TUMOR (PINDBORG’S TUMOR): A CASE REPORT Ahmet Mihmanlı1, Emre Aytu gar1, Nihat Demirtas¸2, Suzan Bayer1, 3 1 Fatma Canan Alatlı , Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Bezmialem Vakif University, Istanbul, Turkey; 2Department of Oral and Maxillofacial Radiology, Faculty of Dentistry, Bezmialem Vakif University, Istanbul, Turkey; 3Department of Pathology, Faculty of Dentistry, Istanbul University, Istanbul, Turkey Calcifying epithelial odontogenic tumor (CEOT) is a rare benign neoplasm and it has been described by pathologist Jens Jorgen Pindborg in 1955. World Health Organization (WHO) in 2005 classified it as a benign odontogenic tumor, which include odontogenic epithelium with mature, fibrous stroma without odontogenic ectomesenchyme. It is a locally aggressive, painless and slow growing tumor and accounts for less than 1% of all odontogenic tumors. CEOT has high rate of recurrence and generally affects the maxillary posterior region. It occurs between 2nd and 6th decade of life without gender preduection. It is detected by clinical, radiographic and histopathological examination. In general they are associated with an impacted tooth. In this paper we present histopathological and radiological features of a giant CEOT in 42-year-old man. Therefore we aimed to investigate the surgical managements of these tumors. Keywords: Odontogenic tumors, histopathology, calcifying epithelial odontogenic tumor, Pindborg tumor
UNICYSTIC AMELOBLABLASTOMA WITH DIVERSE MURAL PROLIFERATION: A CASE REPORT Emre Barıs¸1, Burcu Sengüven1, Süleyman Bozkaya2, Sara Samur Ergüven2, 1 Department of Oral Pathology, Gazi University Faculty of Dentistry, Ankara, Turkey; 2Department of Oral and Maxillofacial Surgery, Gazi University Faculty of Dentistry, Ankara, Turkey Unicystic ameloblastoma is a benign odontogenic neoplasm which includes several clinic-radiological and histological types. Here we are presenting a case of unicystic ameloblastoma in a 12-year-old boy who complained of swelling on the right mandibular molar region. Radiographic examination revealed a well defined multilocular radiolucent lesion around second molar tooth mimicking dentigerous cyst which was extend to vestibular part of first molar. Following incisional biopsy, a diagnosis of unicystic ameloblastoma was made and marsupialisation was performed for reduced the lesion size. The lesion was totally enucleated 15 months after marsupialisation. Histopathological examination of the enucleation specimen exhibited a unicystic ameloblastoma of luminal, intraluminal, and mural type. Intraluminal proliferation was of plexiform pattern and mural proliferation showed unusual histopathological findings, which revealed follicular, acanthomatous areas coexisted with plexiform areas. 6 months follow up till to date has not revealed any signs of recurrence. Keywords: unicystic ameloblastoma, mural proliferation, diverse histology
WHAT IS THE MEANING OF FOCUS SCORE[1 IN ¨ GREN’S SYNDROME? Leyla Haryullah1, Fulya ÇakaSJO la gao glu1, Demet Etit1, Nes¸e Ekinci1, Emel Civas¸1, Mustafa Özmen2, Gerçek Can2, 1Department of Pathology, Izmir Katip Çelebi University Ataturk Training and Research Hospital,