Synthesis of trifluoromethylthiazoles and their application as the photochromic compounds

B59

121

SYNTHESIS

OF TRIFLUOROMETHYLTHIAZOLES

AS THE PHOTOCHROMIC

S. Iwata, Faculty

and K. Tanaka

of Engineering, Tokyo

Seikei

University,

180 (Japan)

5-Lithio-4-trifluoromethylthiazole, corresponding various

thiazole

electrophiles.

pyrazine

gives

The reaction

the tetrakis-substituted

2 is obtained

ring-closure discussed.

derived

and butyllithium,

with octafluorocyclopentene, ethene

APPLICATION

COMPOUNDS

Y. Ishihara,

Musashino-shi,

AND THEIR

reaction

from the

is reactive

with

to

dichlorodicyano-

pyrazine

1 and,

bis(trifluoromethylthiazoly1)

in a moderate

yield.

The reversible

of 2 by photoirradiation

shall be