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SYSTEMIC LUPUS ERYTHEMATOUS MIMETIZING BULLOUS PEMPHIGOID: A CASE REPORT
ABSTRACTS
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radiolucent images associated with the unerupted tooth 48. By mesial was suggestive of dentigerous cyst and by distal presented no defined limits, measuring about 2 cm, with an initial hypothesis of ameloblastoma. An incisional biopsy (distal image) with extraction of tooth 48 was carried out. The histopathology analysis of distal image showed hypercellular, hematopoietic bone marrow characterized by erythroid, granulocytic, and lymphocytic series. A few dilated vascular channels were also observed. There was no abnormality in the morphology of the hematopoietic cells and no evidence of malignant cells. The diagnosis of focal osteoporotic marrow defect was made. The mesial image revealed a dentigerous cyst. Currently, there is no evidence of disease.
SYSTEMIC LUPUS ERYTHEMATOUS MIMETIZING BULLOUS PEMPHIGOID: A CASE REPORT. LARISSA NATIELE MIOTTO, BARROS DE JESSICA HELENA DOTTA, ANALU OLIVEIRA, CLEVERTON ROBERTO DE ANDRADE, MIRIAN APARECIDA ONOFRE, TULIO MORANDIN FERRISSE and, ELAINE MARIA SGAVIOLI MASSUCATO A 43-year-old woman was referred for evaluation of "blister on the gingiva." Intraoral examination revealed erosion on the free marginal gingiva, bacterial plaque accumulation on the cervical and proximal teeth, and some destruction of interdental papilla with reddish coloration. Biopsy was performed after periodontal treatment, and histopathologic analysis evidenced bullous pemphigoid. The patient was treated with topical and systemic corticoid; however, there was no improvement in the clinical aspect. Therefore, complementary examination was done, and the positive ones were anti-nuclei factor and anti double-stranded DNA. A new biopsy was performed, and histopathologic analysis evidenced systemic lupus erythematous. The patient was treated with systemic corticoid and hydroxychloroquine and showed regression of symptoms. Currently, the patient is without lesions and still continues the use of medication. Patients with immunomediated diseases with oral repercussions should be closely monitored because of the overlap of clinical and histopathologic findings.
EXPANSIVE OSSEOUS DYSPLASIA: CASE REPORT AND LITERATURE REVIEW. LARISSA NATIELE MIOTTO, JESSICA HELENA BARROS DE OLIVEIRA, AUDREY DOTTA, ANALU FOSTER LEFORT ROCHA, JORGE ESQUICHE LEON, ROSE MARA ORTEGA and, TULIO MORANDIN FERRISSE Literature review was carried out and found 30 cases. According to the data found, the most affected sex is female at 35 § 16.4 years, with location in the maxilla. A 33-year-old woman was diagnosed as having florid osseous dysplasia through radiographic examinations. Five years later, she was referred, exhibiting an expansive lesion of the mandibular anterior region. The intraoral examination revealed an expansion in the vestibular and lingual cortical bones, and the teeth showed displacement without alterations of pulp vitality testing and pain. The panoramic radiograph showed an expansive mixed lesion. Teeth resorptions were not visualized. The computed tomography showed a dense mixed lesion closely associated with the roots of the mandibular incisors. Intraoral incisional biopsy was performed, which proved difficult to detach from adjacent bone, and the specimen microscopically revealed a benign fibro-osseous lesion. The clinicopathologic
OOOO January 2020 features favored the diagnosis of expansive osseous dysplasia. The patient was referred for surgical evaluation.
OSTEOSARCOMA OF THE ANTERIOR MAXILLA: CONTRIBUTION OF THE DENTAL TEAM IN THE DIAGNOSIS AND IMMEDIATE REHABILITATION. CLAUDIA JOFFILY PARAHYBA, WANESSA MIRANDA E SILVA, JULIA BRUNO, RAFAEL SARLO VILELA, FELIPE PAIVA FONSECA and, EDUARDO RODRIGUES FREGNANI Tumors of jaw are among the most uncommon of all types of neoplasms. Osteosarcoma of the jaw represents a distinct group of lesions from the common type often occurring in long bones, which rarely affects the anterior maxilla. A 43-year-old male patient with a previous history of dental losses in the anterior maxilla region and biopsy results without conclusive diagnosis for 18 months attended the oral medicine service complaining of an asymptomatic hard nodule in the anterior maxilla. An incisional biopsy was performed, and diagnosis was chondroblast osteosarcoma. The patient was referred to the oncologist and head and neck surgeon, received 3 cycles of chemotherapy with cisplatin and doxorubicin, maintained stable disease, and then underwent conservative maxillectomy. The surgical planning included the collaboration of the dental team, with installation of immediate removable maxillary obturator prostheses, allowing the patient more comfort postoperatively and improving in speech, swallowing, and esthetics.
ORAL MELANOMA INVOLVING GINGIVA AND PALATE. LUCAS ALVES DA MOTA SANTANA, THIAGO SANTANA RIBEIRO, e CELESTE SANCHEZ-ROMERO, PAULA ASSUNC ¸ AO ^ NOVAIS, CLEVERSON LUCIANO TRENTO, ANTONIO CARLOS MARQUETI and, SILVIA FERREIRA DE SOUSA A 67-year-old male farmer presented with the complaint of a slightly symptomatic spot in the mouth for the past 2 years. The medical history discussed no abnormalities. Extraoral examination revealed cervical lymphadenopathy on the left side and intraoral examination a blue-black sessile elevated mass with irregular borders, involving the attached vestibular gingiva of teeth 27 and 28, extending to the hard palate and measuring approximately 3.5 cm. Panoramic radiograph did not show bone involvement. A diagnostic hypothesis of oral melanoma was made, and an incisional biopsy was performed. Microscopic findings revealed a proliferation of densely pigmented pleomorphic cells, invading the subepithelial connective tissue in sheets or nests in an organoid fashion. Immunopositivity for S-100, Melan A, and HMB-45 confirmed the diagnosis of melanoma. The patient was referred to an oncology hospital, and, unfortunately, we have no information if he initiated the treatment. Financial Support: CAPES.
LOW-LEVEL LASER THERAPY IN THE TREATMENT OF ORAL PEMPHIGUS VULGARIS: 2 CASE REPORTS. RAQUEL RICHELIEU LIMA DE ANDRADE PONTES, JULIANA SOARES PEREIRA, ANA CAROLINE PENCHINA DE SOUZA, WAGNER PERERIRA COUTINHO FILHO, NANCY DE ASSIS FERREIRA and, RENATO LIESS KREBS
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radiolucent images associated with the unerupted tooth 48. By mesial was suggestive of dentigerous cyst and by distal presented no defined limits, measuring about 2 cm, with an initial hypothesis of ameloblastoma. An incisional biopsy (distal image) with extraction of tooth 48 was carried out. The histopathology analysis of distal image showed hypercellular, hematopoietic bone marrow characterized by erythroid, granulocytic, and lymphocytic series. A few dilated vascular channels were also observed. There was no abnormality in the morphology of the hematopoietic cells and no evidence of malignant cells. The diagnosis of focal osteoporotic marrow defect was made. The mesial image revealed a dentigerous cyst. Currently, there is no evidence of disease.
SYSTEMIC LUPUS ERYTHEMATOUS MIMETIZING BULLOUS PEMPHIGOID: A CASE REPORT. LARISSA NATIELE MIOTTO, BARROS DE JESSICA HELENA DOTTA, ANALU OLIVEIRA, CLEVERTON ROBERTO DE ANDRADE, MIRIAN APARECIDA ONOFRE, TULIO MORANDIN FERRISSE and, ELAINE MARIA SGAVIOLI MASSUCATO A 43-year-old woman was referred for evaluation of "blister on the gingiva." Intraoral examination revealed erosion on the free marginal gingiva, bacterial plaque accumulation on the cervical and proximal teeth, and some destruction of interdental papilla with reddish coloration. Biopsy was performed after periodontal treatment, and histopathologic analysis evidenced bullous pemphigoid. The patient was treated with topical and systemic corticoid; however, there was no improvement in the clinical aspect. Therefore, complementary examination was done, and the positive ones were anti-nuclei factor and anti double-stranded DNA. A new biopsy was performed, and histopathologic analysis evidenced systemic lupus erythematous. The patient was treated with systemic corticoid and hydroxychloroquine and showed regression of symptoms. Currently, the patient is without lesions and still continues the use of medication. Patients with immunomediated diseases with oral repercussions should be closely monitored because of the overlap of clinical and histopathologic findings.
EXPANSIVE OSSEOUS DYSPLASIA: CASE REPORT AND LITERATURE REVIEW. LARISSA NATIELE MIOTTO, JESSICA HELENA BARROS DE OLIVEIRA, AUDREY DOTTA, ANALU FOSTER LEFORT ROCHA, JORGE ESQUICHE LEON, ROSE MARA ORTEGA and, TULIO MORANDIN FERRISSE Literature review was carried out and found 30 cases. According to the data found, the most affected sex is female at 35 § 16.4 years, with location in the maxilla. A 33-year-old woman was diagnosed as having florid osseous dysplasia through radiographic examinations. Five years later, she was referred, exhibiting an expansive lesion of the mandibular anterior region. The intraoral examination revealed an expansion in the vestibular and lingual cortical bones, and the teeth showed displacement without alterations of pulp vitality testing and pain. The panoramic radiograph showed an expansive mixed lesion. Teeth resorptions were not visualized. The computed tomography showed a dense mixed lesion closely associated with the roots of the mandibular incisors. Intraoral incisional biopsy was performed, which proved difficult to detach from adjacent bone, and the specimen microscopically revealed a benign fibro-osseous lesion. The clinicopathologic
OOOO January 2020 features favored the diagnosis of expansive osseous dysplasia. The patient was referred for surgical evaluation.
OSTEOSARCOMA OF THE ANTERIOR MAXILLA: CONTRIBUTION OF THE DENTAL TEAM IN THE DIAGNOSIS AND IMMEDIATE REHABILITATION. CLAUDIA JOFFILY PARAHYBA, WANESSA MIRANDA E SILVA, JULIA BRUNO, RAFAEL SARLO VILELA, FELIPE PAIVA FONSECA and, EDUARDO RODRIGUES FREGNANI Tumors of jaw are among the most uncommon of all types of neoplasms. Osteosarcoma of the jaw represents a distinct group of lesions from the common type often occurring in long bones, which rarely affects the anterior maxilla. A 43-year-old male patient with a previous history of dental losses in the anterior maxilla region and biopsy results without conclusive diagnosis for 18 months attended the oral medicine service complaining of an asymptomatic hard nodule in the anterior maxilla. An incisional biopsy was performed, and diagnosis was chondroblast osteosarcoma. The patient was referred to the oncologist and head and neck surgeon, received 3 cycles of chemotherapy with cisplatin and doxorubicin, maintained stable disease, and then underwent conservative maxillectomy. The surgical planning included the collaboration of the dental team, with installation of immediate removable maxillary obturator prostheses, allowing the patient more comfort postoperatively and improving in speech, swallowing, and esthetics.
ORAL MELANOMA INVOLVING GINGIVA AND PALATE. LUCAS ALVES DA MOTA SANTANA, THIAGO SANTANA RIBEIRO, e CELESTE SANCHEZ-ROMERO, PAULA ASSUNC ¸ AO ^ NOVAIS, CLEVERSON LUCIANO TRENTO, ANTONIO CARLOS MARQUETI and, SILVIA FERREIRA DE SOUSA A 67-year-old male farmer presented with the complaint of a slightly symptomatic spot in the mouth for the past 2 years. The medical history discussed no abnormalities. Extraoral examination revealed cervical lymphadenopathy on the left side and intraoral examination a blue-black sessile elevated mass with irregular borders, involving the attached vestibular gingiva of teeth 27 and 28, extending to the hard palate and measuring approximately 3.5 cm. Panoramic radiograph did not show bone involvement. A diagnostic hypothesis of oral melanoma was made, and an incisional biopsy was performed. Microscopic findings revealed a proliferation of densely pigmented pleomorphic cells, invading the subepithelial connective tissue in sheets or nests in an organoid fashion. Immunopositivity for S-100, Melan A, and HMB-45 confirmed the diagnosis of melanoma. The patient was referred to an oncology hospital, and, unfortunately, we have no information if he initiated the treatment. Financial Support: CAPES.
LOW-LEVEL LASER THERAPY IN THE TREATMENT OF ORAL PEMPHIGUS VULGARIS: 2 CASE REPORTS. RAQUEL RICHELIEU LIMA DE ANDRADE PONTES, JULIANA SOARES PEREIRA, ANA CAROLINE PENCHINA DE SOUZA, WAGNER PERERIRA COUTINHO FILHO, NANCY DE ASSIS FERREIRA and, RENATO LIESS KREBS