The biology of nitric oxide, part 5

The biology of nitric oxide, part 5

1012 Book Reviews PII S0891-5849(96)00288-2 THE BIOLOGY OF NITRIC OXIDE, PART 5 S. MONCADA, J. STAMLER, S. GROSS, E. A. HIGGS, EDITORS Portla...

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1012

Book Reviews

PII S0891-5849(96)00288-2

THE

BIOLOGY

OF NITRIC

OXIDE,

PART

5

S. MONCADA, J. STAMLER, S. GROSS, E. A. HIGGS, EDITORS Portland Press Ltd., London W I N 3AJ, UK, 1996 Part 5, 353 pp, 1996. Price: $160 US

Reviewed by W. A. Pryor BiodynamicsInstitute, LouisianaState University,Baton Rouge, LA 70803, USA

This volume results from the 4th International Meeting on the Biology of Nitric Oxide that was held at Amelia Island in Florida in September 1995. Approximately 1350 scientists took part in that meeting, with approximately 60 presentations and 400 posters. This volume has one-page abstracts from about 40 of the oral presentations and about 270 of the posters. The presentations are divided into sections on biochemistry, molecular biology, immunology, chemistry, pharmacology, physiology, therapy, and "hot topics." The field of nitric oxide research is moving as fast as or faster than any field in science; for that reason, the publisher should be particularly commended on getting a book in the hands of readers only 6 months after the meeting was held. Virtually every topic that you know and love about nitric oxide is covered in this book, in one form or another. Some areas of discussion were gene expression; function and detection of NO; ESR and spintrapping; the role of NO in diseases such as HIV,

stroke, and cancer; NO in the inflammatory response; NO modulations of cytokines and nuclear transcription factors; apoptosis; S-nitrosothiols; and many others. Most, if not all, of the contributions reported in this book of abstracts will ultimately be published. Since none of the reports in this book are longer than a page, and since few present more than one or two tables or figures, the volume is useful mainly as a view of "things to c o m e " in the literature over the next year or so. For persons working in the field, that view forward will serve a useful purpose. The articles are done camera-ready, which was a wise decision from the publisher in order to speed publication. There is both a subject index and an author index, and the subject index is quite detailed. In summary, this book can be recommended, but only to persons working in the field who feel they would benefit from knowing the direction of current research.