- Email: [email protected]
THE CEREBRAL PATHOLOGY OF HEREDITARY CHOREA.
1614 unofficial and had not been submitted to the comWhen education is the avowed object it must surely be a short-sighted policy which encourages individuals to possess themselves of rare specimens, removing to their private cases objects which might have instructed hundreds of future botanists in the field.
movements diminished and
effort arrested them incoordinate and arrhythmic. Speech was hesitating and jerky and difficult to understand owing to the irregular movements of the lips and tongue. The general strength was good. No trophic disturbances or troubles of the sphincters were present. There wer& no stigmata of degeneration, except as regards the ears whichshowed a marked folding of the helix. The patient was. "THE GOVERNMENT AND THE MEDICAL PROFESSION." loquacious and was inclined to slight incoherence of speech. Obstinate constipation A GENTLEMAN has made a communication to us with There was some arterio-sclerosis. The urine was free from albumin or sugar. The prevailed. regard to the leading article in THE LANCET of Jane died from cachexia in March, 1900. The necropsy. 1st, p. 1551, on "The Government and the Medical patient all the internal organs were small and wasted in showed that Profession," who signs himself "An Onlooker"but who There was old tuberculosis of both apices of the. appearance. does not do us the compliment of trusting his name to Examination of. brain was of normal volume. The lungs. us. The gist of his communication is that Mr. M’Kenna’s the frontal after convolution staining with. ascending method of bringing forward Dr. Irvine’s case from Mr. an infiltration of small round cells in. Nissl’s method showed Markham’s side constituted a pantomime and that the House of Commons, being weary and hungry, objected to hear the molecular layer, but the medium-sized and small bloodHe says that vessels appeared normal. The nuclei of these round cells. the matter debated at the dinner-hour. the House preferred fair play and dinner to all else, were blue and homogeneous in appearance, and were clothed a unlike normal neuroglia cells but what sort of fair play was meted out by Mr. with pellicle of protoplasm in These cells occurred nests of two, three, or four, and in Chamberlain and Sir John Gorst to the General Medical the sacs of the pericellular larger nerve-cells they were. Council, the disciplinary body of the medical profession, we numc rbus and conspicuous. The pyramidal cells showed an. Our anonymous correspondent is very are unable to say. exces3 of yellow pigment in proportion with the age of the vigorous in his assertions that Mr. M’Kenna’s action was directed against Mr. Chamberlain and not inspired by a love patient. Some pyramidal cells were pale and almost uniof justice. Mr. M’Kenna probably knows the truth of the formly stainless. Only the larger cortical vessels showed pro-matter which is really of no consequence whatever. He liferatiln of the perivascular sheath, especially in their the white matter. The ascending parietal properly raised a very important question in the House of course through showed similar changes. No degenerated nerve convolution Commons and whether he did so from a 7)on motif or not is a could found with Marchi’s method in Exner’s. fibres be secondary matter. plexus. The cervical spinal cord showed with Nissl’s method a normal condition of the nerve-cells. The spinal nerve-THE CEREBRAL PATHOLOGY OF HEREDITARY roots and meninges were normal. Hence the lesion was one. CHOREA. AN interesting contribution wmcn throws ngnt on tne of the cerebral cortex and from its nature it appeared to be. incurable. of or hitherto obscure to
was
mittee.
for
a
while.
voluntary
All these movements
were
*-
-
pathology
hereditary
Huntington’s
chorea has been published in the Revue Ne1l’l’ologiqlle of May 15th by Lannois, Paviot, and Mouisset. In a previous publication,l Keraval and Raviart stated that they found the following changes in the nervous system in a fatal case of hereditary chorea: rarefaction of the perinuclear protoplasm, even to the extent of disintegration, in the large pyramidal and small nerve-cells of the cerebral cortex ; an infiltration of small round cells into the pericellular and perivascular spaces ; swollen nuclei and faint staining of the protoplasm of the cell-bodies in the nerve-cells of the central convolutions ; and similar changes in the cells of the spinal cord, especially in Clarke’s column. Weigert’s method also showed a diminution of the nerve-fibres in the superficial layer of the cerebral cortex (Exner’s plexus) and a moniliform degeneration of nerve-fibres in various depths of the cortex. The "small round cells" alluded to above stained green with Rosin’s methods, like the nuclei of neuroglia cells. Kattwinkel who investigated a case found a similar of small round cells, but regarded them as leucocytes. The present case was as follows. aged 68 years, by occupation a gardener, had suffered
proliferation
mononuclear A man,
___
THE JUBILEE DINNER OF THE ISLINGTON MEDICAL SOCIETY. THE dinner in commemoration of the fiftieth year of the above society was held in the Victoria Hall of the Criterion Restaurant on June 5th. Dr. James Grey Glover was in the chair, and among the guests were Sir William Turner, K C.B., Dr. W. Bruce of Dingwall, Dr. Mitchell Bruce, Inspector-General Grant, Sir Albert Rollit,. M.P., Sir John Glover, J.P., Mr. T. Lough, M.P., and Dr. Barlow, the newly appointed Dean of Peterborough,. until recently vicar of Islington. After the usual Dr. and toasts Glover loyal patriotic proposed the toast of"The Islington Medical Society." He gave a. sketch of the foundation of the society in 1850, there being12 original members, of whom only one, Mr. Jackson, survived. He, although 87 years of age. would have been, there that night but that he was suffering from his ninthattack of influenza. The speeches were interspersed withsongs and musical sketches contributed by Dr. W. K. Byrne, Mr. Thomas Jago, Mr. Seymour Dicker, and others. The toast of "The Guests"was proposed by Dr. Alexander Morison. and replied to by Sir William Turner and others. Great, praise is due to the secretary, Mr. David Keele, for the success with which everything passed off, and the society may congratulate itself upon a very fitting jubilee festivals
from chorea since 1872, but since 1896 as the result of an accident the symptoms had grown very severe. His father had died at the age of 80 years from the same complaint, and the patient’s only brother, aged 65 years, was a sufferer from chronic chorea for many years. There was no history of alcohol or syphilis in the patient. He was thin and emaciated and had twitching of the face, lips, and eyes resembling NAILS IN BUNS AND CHEESE. and silence both occurred grimaces. They during speech A CORRESPONDENT informs us that within a month he has and were accompanied by jerky movements of the eyeballs heard of three tacks being found in buns and a bent nail and of the nostrils. There were also present oscillations of of an inch long in a piece of cheese. One of three-quarters the head and purposeless and choreic movements of the the tacks was not discovered until it had entered the month arms, legs, and trunk. On the patient lying down these of the person eating the bun and the presence of the nail was 1 Archives de also detected in the same way. In the case of an adult who Neurologie, 1900.
movements diminished and
effort arrested them incoordinate and arrhythmic. Speech was hesitating and jerky and difficult to understand owing to the irregular movements of the lips and tongue. The general strength was good. No trophic disturbances or troubles of the sphincters were present. There wer& no stigmata of degeneration, except as regards the ears whichshowed a marked folding of the helix. The patient was. "THE GOVERNMENT AND THE MEDICAL PROFESSION." loquacious and was inclined to slight incoherence of speech. Obstinate constipation A GENTLEMAN has made a communication to us with There was some arterio-sclerosis. The urine was free from albumin or sugar. The prevailed. regard to the leading article in THE LANCET of Jane died from cachexia in March, 1900. The necropsy. 1st, p. 1551, on "The Government and the Medical patient all the internal organs were small and wasted in showed that Profession," who signs himself "An Onlooker"but who There was old tuberculosis of both apices of the. appearance. does not do us the compliment of trusting his name to Examination of. brain was of normal volume. The lungs. us. The gist of his communication is that Mr. M’Kenna’s the frontal after convolution staining with. ascending method of bringing forward Dr. Irvine’s case from Mr. an infiltration of small round cells in. Nissl’s method showed Markham’s side constituted a pantomime and that the House of Commons, being weary and hungry, objected to hear the molecular layer, but the medium-sized and small bloodHe says that vessels appeared normal. The nuclei of these round cells. the matter debated at the dinner-hour. the House preferred fair play and dinner to all else, were blue and homogeneous in appearance, and were clothed a unlike normal neuroglia cells but what sort of fair play was meted out by Mr. with pellicle of protoplasm in These cells occurred nests of two, three, or four, and in Chamberlain and Sir John Gorst to the General Medical the sacs of the pericellular larger nerve-cells they were. Council, the disciplinary body of the medical profession, we numc rbus and conspicuous. The pyramidal cells showed an. Our anonymous correspondent is very are unable to say. exces3 of yellow pigment in proportion with the age of the vigorous in his assertions that Mr. M’Kenna’s action was directed against Mr. Chamberlain and not inspired by a love patient. Some pyramidal cells were pale and almost uniof justice. Mr. M’Kenna probably knows the truth of the formly stainless. Only the larger cortical vessels showed pro-matter which is really of no consequence whatever. He liferatiln of the perivascular sheath, especially in their the white matter. The ascending parietal properly raised a very important question in the House of course through showed similar changes. No degenerated nerve convolution Commons and whether he did so from a 7)on motif or not is a could found with Marchi’s method in Exner’s. fibres be secondary matter. plexus. The cervical spinal cord showed with Nissl’s method a normal condition of the nerve-cells. The spinal nerve-THE CEREBRAL PATHOLOGY OF HEREDITARY roots and meninges were normal. Hence the lesion was one. CHOREA. AN interesting contribution wmcn throws ngnt on tne of the cerebral cortex and from its nature it appeared to be. incurable. of or hitherto obscure to
was
mittee.
for
a
while.
voluntary
All these movements
were
*-
-
pathology
hereditary
Huntington’s
chorea has been published in the Revue Ne1l’l’ologiqlle of May 15th by Lannois, Paviot, and Mouisset. In a previous publication,l Keraval and Raviart stated that they found the following changes in the nervous system in a fatal case of hereditary chorea: rarefaction of the perinuclear protoplasm, even to the extent of disintegration, in the large pyramidal and small nerve-cells of the cerebral cortex ; an infiltration of small round cells into the pericellular and perivascular spaces ; swollen nuclei and faint staining of the protoplasm of the cell-bodies in the nerve-cells of the central convolutions ; and similar changes in the cells of the spinal cord, especially in Clarke’s column. Weigert’s method also showed a diminution of the nerve-fibres in the superficial layer of the cerebral cortex (Exner’s plexus) and a moniliform degeneration of nerve-fibres in various depths of the cortex. The "small round cells" alluded to above stained green with Rosin’s methods, like the nuclei of neuroglia cells. Kattwinkel who investigated a case found a similar of small round cells, but regarded them as leucocytes. The present case was as follows. aged 68 years, by occupation a gardener, had suffered
proliferation
mononuclear A man,
___
THE JUBILEE DINNER OF THE ISLINGTON MEDICAL SOCIETY. THE dinner in commemoration of the fiftieth year of the above society was held in the Victoria Hall of the Criterion Restaurant on June 5th. Dr. James Grey Glover was in the chair, and among the guests were Sir William Turner, K C.B., Dr. W. Bruce of Dingwall, Dr. Mitchell Bruce, Inspector-General Grant, Sir Albert Rollit,. M.P., Sir John Glover, J.P., Mr. T. Lough, M.P., and Dr. Barlow, the newly appointed Dean of Peterborough,. until recently vicar of Islington. After the usual Dr. and toasts Glover loyal patriotic proposed the toast of"The Islington Medical Society." He gave a. sketch of the foundation of the society in 1850, there being12 original members, of whom only one, Mr. Jackson, survived. He, although 87 years of age. would have been, there that night but that he was suffering from his ninthattack of influenza. The speeches were interspersed withsongs and musical sketches contributed by Dr. W. K. Byrne, Mr. Thomas Jago, Mr. Seymour Dicker, and others. The toast of "The Guests"was proposed by Dr. Alexander Morison. and replied to by Sir William Turner and others. Great, praise is due to the secretary, Mr. David Keele, for the success with which everything passed off, and the society may congratulate itself upon a very fitting jubilee festivals
from chorea since 1872, but since 1896 as the result of an accident the symptoms had grown very severe. His father had died at the age of 80 years from the same complaint, and the patient’s only brother, aged 65 years, was a sufferer from chronic chorea for many years. There was no history of alcohol or syphilis in the patient. He was thin and emaciated and had twitching of the face, lips, and eyes resembling NAILS IN BUNS AND CHEESE. and silence both occurred grimaces. They during speech A CORRESPONDENT informs us that within a month he has and were accompanied by jerky movements of the eyeballs heard of three tacks being found in buns and a bent nail and of the nostrils. There were also present oscillations of of an inch long in a piece of cheese. One of three-quarters the head and purposeless and choreic movements of the the tacks was not discovered until it had entered the month arms, legs, and trunk. On the patient lying down these of the person eating the bun and the presence of the nail was 1 Archives de also detected in the same way. In the case of an adult who Neurologie, 1900.