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The circulatory and respiratory disturbances of acute compressed air illness and the administration of oxygen as a therapeutic measure
Erllst, Curt: 745,
Localized
Edemas
in Human
Beings.
Deutsche
wetI.
~l;(.ilriHI.:tr.
a1 L
1039.
Vasoneurotie and hypertonic (red veloping local edemas in the skin and of several hundred vasoneurotic and of spastic-atonic capillaries. But the of the minute vessels; there are also The elasticity of the skin is decreased; showed a decrease in elasticity from injection of 1:1,000,000 solution of more pronounc,ed reaction, more lasting an increased amount of fluid in the showed increased capillary permeability.
hypertonic) patients are ))redisposed to demucous membranes. capillary examination hypertonic patients showed characteristics local edemas are not due only to the changes present typical changes in the skin tissue. rnco,sured with an elastometer (Shade), it 14 per eent to 38 per cent. Intrarutaneous morphine gave in this type of patients a and larger wheals anti redness, scggesting skin. Intracutaneous histamine injection
Vasoneurotic individuals are predisposed to certain ulcer, red hypertension, Raynaud ‘s disease, ulcerative and certain types of asthma, cystitis, and glaucoma.
diseases sueE colitis. MOniGre
a.s gast.ric ‘s disease, J. IZ.
Behnke, Albert R., Shaw, Louis A., Messer, Anne C., Thomson, Robert M., and Motley, E. Preble: The Circulatory and Respiratory Disturbances of Acute Compressed Air Illness and the Administration of Oxygen as a Therapeutic Measure. Am. J. Physiol. 114: 526, 1036. Nitrogen emboli were produced in the blood of anesthetized dogs by rapid decon,pression from air compressed to 65 pound gauge pressure for 106 minutes. Rapid breathing, temporary rise followed by a fall in the blood pressure, retarded pulse rate, oxygen unsaturation of the arterial blood, and a marked inereasc in the arteriovenous difference were noted. The rapid breathirlg aml unsaturation of the arterial blood arc attributed to rmbolie blockage of the puInlouary circulation, and the fall in blood pressure and increased arteriovenous difference are attributed to embolic injury to the nerve tissue which controls circulation. E. A.
Smith, Fred N., Rathe, H. W., and Paul, Disease of the Coronary Arteries. Arch.
IX: Theophylline Int. Med. 56:
in the 1250, 236.
Treatment
of
It is important that measures be directed toward the restoration and maintenance of an efficient coronary circulation in the treatment of disease of the coronary arteries. The preparations of theophylline have a marked dilating action on the coronary vessels in the experimental animal, and clinical experience has demonstrated that they are valuable therapeutic agents in the treatment of diaease of the coronary arteries, regardless of whether the cardiac disability is expressed by eongestive failure, paroxysmal dyspnea, angina on effort, or occlusion of the coronary arteries. results and failures are encountered, but Q ues t ionable this is to be expected in the more advanced forms of the disease. Theophylline should be prescribed as soon as the diagnosis of disease of the coronary arteries is established, and its administration should be continued for a. long period, in order to insure the maximum benefit from the medication. It should be remembered, however, that this constitutes only one measure in the treatment and, except for experimental purposes, should not be employed to the exclusion of other established means of restoring the cardiac function.
Localized
Edemas
in Human
Beings.
Deutsche
wetI.
~l;(.ilriHI.:tr.
a1 L
1039.
Vasoneurotie and hypertonic (red veloping local edemas in the skin and of several hundred vasoneurotic and of spastic-atonic capillaries. But the of the minute vessels; there are also The elasticity of the skin is decreased; showed a decrease in elasticity from injection of 1:1,000,000 solution of more pronounc,ed reaction, more lasting an increased amount of fluid in the showed increased capillary permeability.
hypertonic) patients are ))redisposed to demucous membranes. capillary examination hypertonic patients showed characteristics local edemas are not due only to the changes present typical changes in the skin tissue. rnco,sured with an elastometer (Shade), it 14 per eent to 38 per cent. Intrarutaneous morphine gave in this type of patients a and larger wheals anti redness, scggesting skin. Intracutaneous histamine injection
Vasoneurotic individuals are predisposed to certain ulcer, red hypertension, Raynaud ‘s disease, ulcerative and certain types of asthma, cystitis, and glaucoma.
diseases sueE colitis. MOniGre
a.s gast.ric ‘s disease, J. IZ.
Behnke, Albert R., Shaw, Louis A., Messer, Anne C., Thomson, Robert M., and Motley, E. Preble: The Circulatory and Respiratory Disturbances of Acute Compressed Air Illness and the Administration of Oxygen as a Therapeutic Measure. Am. J. Physiol. 114: 526, 1036. Nitrogen emboli were produced in the blood of anesthetized dogs by rapid decon,pression from air compressed to 65 pound gauge pressure for 106 minutes. Rapid breathing, temporary rise followed by a fall in the blood pressure, retarded pulse rate, oxygen unsaturation of the arterial blood, and a marked inereasc in the arteriovenous difference were noted. The rapid breathirlg aml unsaturation of the arterial blood arc attributed to rmbolie blockage of the puInlouary circulation, and the fall in blood pressure and increased arteriovenous difference are attributed to embolic injury to the nerve tissue which controls circulation. E. A.
Smith, Fred N., Rathe, H. W., and Paul, Disease of the Coronary Arteries. Arch.
IX: Theophylline Int. Med. 56:
in the 1250, 236.
Treatment
of
It is important that measures be directed toward the restoration and maintenance of an efficient coronary circulation in the treatment of disease of the coronary arteries. The preparations of theophylline have a marked dilating action on the coronary vessels in the experimental animal, and clinical experience has demonstrated that they are valuable therapeutic agents in the treatment of diaease of the coronary arteries, regardless of whether the cardiac disability is expressed by eongestive failure, paroxysmal dyspnea, angina on effort, or occlusion of the coronary arteries. results and failures are encountered, but Q ues t ionable this is to be expected in the more advanced forms of the disease. Theophylline should be prescribed as soon as the diagnosis of disease of the coronary arteries is established, and its administration should be continued for a. long period, in order to insure the maximum benefit from the medication. It should be remembered, however, that this constitutes only one measure in the treatment and, except for experimental purposes, should not be employed to the exclusion of other established means of restoring the cardiac function.