THE CNV IN REACTIVE DEPRESSIVES AND NORMALS M. ELTON,
R. DE JONG and R. FERSTL
Max Plarlck-Institut
furPsychiatric,
Munchet~, W. Germatg
The recent increase in interest in the interstimulus interv,-’ (ISI) revealing two or more separate components in the CNV has not been applied to psychiatric groups. Using a short ISI depressives have lower amplitude CNVs than do normals (Donchin. 1978). The present study investigates the comparative stability of distinct CNV components in depressives, in comparison to normal controls. and their responsiveness to motivational manipulation. Twenty patients were recorded on admission to, and discharge from hospital together with 20 age-sex matched normals. Subjects were recorded under a fixed 6 set foreperiod reaction time task in two conditions. The second differed from the first only in that 25 Pfennigs could be won for each reaction faster than the criterion time which was individually determined. EEG was recorded between vertex and left mastoid. and eye movement monitored. Feedback on performance was given after each trial via the fixation lights. Stimulus delivery, feedback. collection were controlled on-line using a PDP 8E which was subsequently averaging
the EEG following
exclusion
of contaminated
and data used for
trials.
On admission patients failed to demonstrate a clear increase in late negativity particularly in the motivated condition. On discharge negativity was increased over earlier dition.
levels in the motivated condition, and contrasted with the unmotivated conAn early CNV component was evident in all conditions. Results are further
presented
as to the relative
the experimental
groups,
size of the components
and their individual
over time within
relationships
and between
to psychopathology.
Reference Donchin, E. (1978). Cognitive psychophysiology. In: Calloway, S.H. (Eds). Event-related Brain Potentials in Man. New York:
THE CONTIGENT NEGATIVE VARIATION ACQUISITION AND EXTINCTION JOHN LUMSDEN, Department