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The cyclotron of the biochemical research foundation
Feb., r94o.] BIOCHEMICAL RESEARCH FOUNDATION.
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b y greatly increasing the frequency induces parallel leakages with s u b s e q u e n t error in measurement. Therefore in the design of a c o n d u c t i v i t y cell of small volume concessions must be made on one or more of these points.
The Cyclotron of the Biochemical Research Foundation. - - A . J. ALLEN, M. B. SAMPSON AND R. G. FRANKLIN. (JouRNAL OF THE FRANKLIN INSTITUTE, 228: 543, I939.) Certain features of the Biochemical Research F o u n d a t i o n cyclotron, which m a y be of interest to those building a similar machine, are presented: (I) The design and construction of the magnetic circuit, (2) results of a survey of the magnetic field with and w i t h o u t " s h i m m i n g , " (3) the construction and dimensions of the v a c u u m t a n k and deflector, (4) the design of dee supports with a convenient a r r a n g e m e n t for the a d j u s t m e n t of the dees, (5) modified ion sources using tungsten ribbon filaments, one of which enables the cyclotron to deliver a current of at least 3 ° microamperes of deuterons at I I Mev. on an external target, (6) a high frequency system for supplying voltage to the dees. Attempts to Detect a Reaction Between Human Allergic Serum and Its Antigen,--~JOHN 5{. NEWF~LL. (Journal of Allergy, xI: 35, I939.) Does the h u m a n sufferer from h a y fever or a s t h m a have an a n t i b o d y in his blood which will react in the test tube with the material t h a t causes the trouble? In the lower animals it is c o m m o n to find antibodies which precipitate the substance to which the animal is sensitive. However, workers in the field of h u m a n allergy have not been able to find such antibodies and it is generally believed that the beneficial results of injections are due to reactions which take place in the living cells and not in the fluids of the blood. This question was examined to see w h e t h e r newly developed m e t h o d s of studying proteins could detect a n y reactions between h u m a n allergic serum and the substance to which the donor of the serum was sensitive. In the first experiment the serum of a person sensitive to rabbit hair and to rabbit serum was examined b y means of the air-driven ultracentrifuge. This h u m a n serum, as do the sera of most adults, contained antitoxin to staphylococcus
263
b y greatly increasing the frequency induces parallel leakages with s u b s e q u e n t error in measurement. Therefore in the design of a c o n d u c t i v i t y cell of small volume concessions must be made on one or more of these points.
The Cyclotron of the Biochemical Research Foundation. - - A . J. ALLEN, M. B. SAMPSON AND R. G. FRANKLIN. (JouRNAL OF THE FRANKLIN INSTITUTE, 228: 543, I939.) Certain features of the Biochemical Research F o u n d a t i o n cyclotron, which m a y be of interest to those building a similar machine, are presented: (I) The design and construction of the magnetic circuit, (2) results of a survey of the magnetic field with and w i t h o u t " s h i m m i n g , " (3) the construction and dimensions of the v a c u u m t a n k and deflector, (4) the design of dee supports with a convenient a r r a n g e m e n t for the a d j u s t m e n t of the dees, (5) modified ion sources using tungsten ribbon filaments, one of which enables the cyclotron to deliver a current of at least 3 ° microamperes of deuterons at I I Mev. on an external target, (6) a high frequency system for supplying voltage to the dees. Attempts to Detect a Reaction Between Human Allergic Serum and Its Antigen,--~JOHN 5{. NEWF~LL. (Journal of Allergy, xI: 35, I939.) Does the h u m a n sufferer from h a y fever or a s t h m a have an a n t i b o d y in his blood which will react in the test tube with the material t h a t causes the trouble? In the lower animals it is c o m m o n to find antibodies which precipitate the substance to which the animal is sensitive. However, workers in the field of h u m a n allergy have not been able to find such antibodies and it is generally believed that the beneficial results of injections are due to reactions which take place in the living cells and not in the fluids of the blood. This question was examined to see w h e t h e r newly developed m e t h o d s of studying proteins could detect a n y reactions between h u m a n allergic serum and the substance to which the donor of the serum was sensitive. In the first experiment the serum of a person sensitive to rabbit hair and to rabbit serum was examined b y means of the air-driven ultracentrifuge. This h u m a n serum, as do the sera of most adults, contained antitoxin to staphylococcus