The Effect of Dose on Local Control of Prostate Cancer

The Effect of Dose on Local Control of Prostate Cancer

Medical Dosimetry 62 Int. J. Radiation Oncology, Biology, Physics, Vol. 15, December 1988, pp. 1465-1473 The Cr&eil method is a simple system for i...

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Medical Dosimetry

62

Int. J. Radiation Oncology, Biology, Physics, Vol. 15, December 1988, pp. 1465-1473

The Cr&eil method is a simple system for intracavitary therapy of cervical and uterine cancer. The system consists of a plastic cervico-vaginal moulage (which can be custom made for each patient) and is loaded with 0.5 mm diameter 192Ir wire sources. Treatment can be performed in a single application, radioprotective measures are simple and the patient is not restricted to his bed.

THE Emcr

OF DOSEON LOCALCONTROL OF PROSTATECANCER

G. E. Hanks, M.D., K. L. Marty, M.S., and J. J. Diamond, Ph.D. University of Pennsylvania, Fox Chase Cancer Center, Philadelphia, PA

Volume 14, Number 1, 1989

Department of Radiation Oncology, Medical College of Wisconsin, 8700 W. Wisconsin Avenue, Milwaukee, WI 53226 Department of Pathology, Zablocki Veteran’s Administration Hospital, 5000 W. National Avenue, Milwaukee, WI 53295 Int. J. Radiation Oncology, Biology, Physics, Vol. 15,

December 1988, pp. 144-1446 This article discusses two cases in which both adult patients developed ARDS following limited thoracic irradiation for lung cancer. Autopsy findings in both irradiated and unirradiated volumes of lung were consistent with hylaine membrane charges. The possible relationship between radiation therapy to limited lung volumes and the development of ARDS is discussed.

American College of Radiology, Philadelphia, PA Int. J. Radiation Oncology, Biology, Physics, Vol. 15,

December 1988, pp. 1299-1305 Surveys of 1516 prostate cancer patients have been combined and analyzed for the effect of dose on infield recurrence. No dose effect was observed for stage A cancers within the dose range of 5500 cGy to >7000 cGy. In stage B a dose range of 6000 cGy to 6999 cGy was appropriate to obtain best local control. Stage C cancer requires a dose 27000 cGy to obtain local control and the increased morbidity of this high dose appears to be justified in this stage of the disease. THE ASSOCIATION OF ADULTRESPIRATORY DISTRESS SYNDROME (ARDS) WITHTHORACICIRRADIATION (RT) Roger E. Byhardt, M.D., Ross Abrams, M.D., and Urias Almagro, M.D.

DESIGNAND CHARACTERISTICS OF A FACILITYFOR TOTAL-BODYAND LARGEFIELDIRRADIATION Wendell R. Lutz, Ph.D., Peter W. Dougan, Ph.D., and Bebqt E. Bjamgard, Ph.D. Joint Center for Radiation Therapy, Harvard Medical School, Boston, MA 02 115 Int..J. Radiation Oncology, Biology, Physics,

Vol. 15, Oct. 1988, pp. 1035-1040 A facility has been built in which two 4 MV linear accelerators are used for total body irradiation. One accelerator is supported from the ceiling and the other is placed in a floor pit. The patient lies supine on a light movable support which is halfway between the sources. The maximum distance between the sources is 410 cm. A special flattening filter is used which maintains the dose rate in air within &3% over the central 70 X 200 cm2 of the field.