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The effect of pregnancy upon experimental hypertension in the rabbit
SELECTED
The
characteristic
laboratory
No evidence was hemolytic streptococcus influenza virus. Rheumatic
finding
obtained to of proved
recurrences
were
not
ABSTRACTS
283
mas a relative
suggest that pathogenicity precipitated
the
leucopenia. virulence of a Group was increased by this
by
the
influenza
A Beta strain of
outbreak. AUTHORS.
Walsh, B. J., and Sprague, H. B.: Character With Active Rheumatic Fever. Am. J. Dis.
of Congestive Failure in Children Child. 61: 1003, 1941.
The clinical features of congestive failure in disease are described, the observations being based dren between the ages of. 3 and 15 years who were April 1, 1940, at the House of the Good Samaritan. The initial signs fever and congestive
of heart failure in these failure were enlargement A accompanied by unexpected gain in weight. and active rheumatic fever preferred to lie flat puttlness of the face, which caused them to look ited
Pulmonary rbles to the terminal
were seldom heard in these stages of the illness.
children with rheumatic heart on a study of forty-four chilseen between July 1, 1937, and
forty-four children with rheumatic of the liver and putliness of the face few children with congestive failure in bed. These children had marked as if they had primary renal disease. children,
their
appearance
being
lim-
Other important evidences of congestive failure in children with rheumatic fever and congestive failure were high venous pressure apparent at the onset of the failure, a shift of the electrical axis of the heart to the right, which increased with progression of the heart failure and decreased or disappeared with the patient’s improvement or recovery, and a well-marked diastolic gallop rhythm along the upper left
sternal
border. AUTHORS.
Corbit, J. D., Jr.: The Effect of Pregnancy Upon Experimental the Rabbit. Am. J. M. SC. 201: 876, 1941.
Hypertension
in
A study was made of the fluctuations in: a, blood pressure; b, blood urea; and c, in the excretion of urinary protein during pregnancy in normal rabbits, and in rabbits in which arterial tension was previously raised by the experimental induction of renal ischemia. It was found in both groups of animals that pregnancy tended to bring about a lowering of the systolic pressure a few days before the onset of labor. The extent of this fall amounted to about 20 per cent of the pre-pregnancy tension. The return of pressure to the pre-pregnancy level occurred gradually during the first two to three weeks post partum. In the normal animal these fluctuations of arterial tension were not accompanied by significant alterations of blood urea, nor by proteinuria. In the renal ischemic animals, however, there was a coincidental, slight, prepartal fall of blood urea, and a tendency to proteinuria. In no animal was there evidence to indicate that these changes were due to ill health. The normal gestational increase of maternal body weight took place, the pregnancies were normal in duration, and the number of pups born was normal for this species. The extent of the prepartal of fetuses present.
fall
of blood
pressure
was proportionate
to the number AUTHOR.
The
characteristic
laboratory
No evidence was hemolytic streptococcus influenza virus. Rheumatic
finding
obtained to of proved
recurrences
were
not
ABSTRACTS
283
mas a relative
suggest that pathogenicity precipitated
the
leucopenia. virulence of a Group was increased by this
by
the
influenza
A Beta strain of
outbreak. AUTHORS.
Walsh, B. J., and Sprague, H. B.: Character With Active Rheumatic Fever. Am. J. Dis.
of Congestive Failure in Children Child. 61: 1003, 1941.
The clinical features of congestive failure in disease are described, the observations being based dren between the ages of. 3 and 15 years who were April 1, 1940, at the House of the Good Samaritan. The initial signs fever and congestive
of heart failure in these failure were enlargement A accompanied by unexpected gain in weight. and active rheumatic fever preferred to lie flat puttlness of the face, which caused them to look ited
Pulmonary rbles to the terminal
were seldom heard in these stages of the illness.
children with rheumatic heart on a study of forty-four chilseen between July 1, 1937, and
forty-four children with rheumatic of the liver and putliness of the face few children with congestive failure in bed. These children had marked as if they had primary renal disease. children,
their
appearance
being
lim-
Other important evidences of congestive failure in children with rheumatic fever and congestive failure were high venous pressure apparent at the onset of the failure, a shift of the electrical axis of the heart to the right, which increased with progression of the heart failure and decreased or disappeared with the patient’s improvement or recovery, and a well-marked diastolic gallop rhythm along the upper left
sternal
border. AUTHORS.
Corbit, J. D., Jr.: The Effect of Pregnancy Upon Experimental the Rabbit. Am. J. M. SC. 201: 876, 1941.
Hypertension
in
A study was made of the fluctuations in: a, blood pressure; b, blood urea; and c, in the excretion of urinary protein during pregnancy in normal rabbits, and in rabbits in which arterial tension was previously raised by the experimental induction of renal ischemia. It was found in both groups of animals that pregnancy tended to bring about a lowering of the systolic pressure a few days before the onset of labor. The extent of this fall amounted to about 20 per cent of the pre-pregnancy tension. The return of pressure to the pre-pregnancy level occurred gradually during the first two to three weeks post partum. In the normal animal these fluctuations of arterial tension were not accompanied by significant alterations of blood urea, nor by proteinuria. In the renal ischemic animals, however, there was a coincidental, slight, prepartal fall of blood urea, and a tendency to proteinuria. In no animal was there evidence to indicate that these changes were due to ill health. The normal gestational increase of maternal body weight took place, the pregnancies were normal in duration, and the number of pups born was normal for this species. The extent of the prepartal of fetuses present.
fall
of blood
pressure
was proportionate
to the number AUTHOR.