The effect of severe hypothermia on the central nervous system and on peripheral nerves

The effect of severe hypothermia on the central nervous system and on peripheral nerves

96 ABSTRACTS OF I N T E R E S T once, 8, or 20 times. During rewarming there was a gradual accumulation of ascorbic acid in the adrenal cortex with ...

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96

ABSTRACTS OF I N T E R E S T

once, 8, or 20 times. During rewarming there was a gradual accumulation of ascorbic acid in the adrenal cortex with a reappearance of zonal distribution. Normal content and distribution of ascorbic acid was attained 48 hr following the restor,ttion of n ormothermia.

The Effect of Severe Hypothermia on the Central Nervous System and on Peripheral Nerves. BEX.IAMIN, I:I. B., P. Jocm.~m;:,x', W. JocmMsl.:,~, AND A. ]3ECKE4¢. Rev. Canad. Biol., 22: 433-436, 1963. In comparing the brains and sciatic nerves of rats l,hat had survived severe hyl)othermia (body temperature, 45 ° to" 550F) by immersion i n a water bsth for periods r.mging from 25 t o 90 rain with normothermic animals that were sacrificed, no alterations were seen on either a gross or a histological basis. Controls were indistinguishable from experimental animals. The cause of the temporary paresis, obviously a reversible phenomenon, has no adequate exl)lanation.

Elcctrocortieogram of the Young Animal in Hypothermia a n d in l l y p e r t h e r m i a (l~lectrocortlcogramn;e du jennc animal sous hypothermie et sons l ~ y p e r t h e r m i e ) . BLOZ0VSl~I, D., aND M. BLozovsi,u. J. Physiol. (Par.), 55: 115116, 1963. Electrocortieograms were obt,dned from eurarized young an(l ,tdult nil)bits and chickens during immersion in warm or cold water. No significant differences were observed in the response of young and adult "aninmls i,o moderate hypoihern~i,l (25°(;). Cooling to 15°C was associated with .l progressive decrease in the frequency of cortical diseliarges. The re-establishment of the eortie,fl r h y l h m during rewnrming was slower in adult ,nnireals, During moderate hyperthermia (,12°C), the amplitude "rod frequency of disctmrges increased in all animals, but convulsive activity was more frequent in young "mlmals. Extreme hyperttmrmia (45 ° lo 46°0) produce(l a further increase in the amplitude of discharges, while the frequency deere,~sed until irreversible arrest occurred.