- Email: [email protected]
The effects of intrathecal fentanyl in transurethral resection of prostat syndrome surgery under spinal anaesthesia
30
Posters
•
Central Nerve Blocks IV
171. The effects of intrathecal fentanyl in transurethral resection of prostat syndrome surgery under spinal anaesthesia Ozgurel O Department of Anaesthesiology, Akdeniz University, Antalya, Turkey Background and goal of study: The purpose of this study was to investigate the effects of adding intrathecal fentanyl to low dose hyperbaric bupivacaine in transurethral resection of prostat syndrome surgery. Material and methods: Forty-five patients were randomly allocated into three groups of 15. Spinal anaesthesia was performed between L3-4 interspace with a 25 G spinal needle in the left lateral position. In Group 1, intrathecal 10 mg hyperbaric bupivacaine 0.5% in 3 ml; in Group 2, 10 mg hyperbaric bupivacaine 0.5% ⫹ 12.5 micg fentanyl in 3 ml, and in Group 3, 10 mg hyperbaric bupivacaine 0.5% ⫹ 25 micg fentanyl in 3 ml were administered. Patients were taken to litotomy position after keeping them in the supine for 10 minutes. Maximum sensorial and motor block levels, regression time of sensorial block to the L1 dermatome, time to the first analgesic requirement during the postoperative period, side effects and complications were recorded. Results and discussion: Maximum sensorial block levels were significantly higher in group III than those in other groups (9.13 ⫾ 1.59, 9.46 ⫾ 1.06, and 7.73 ⫾ 1.75, respectively; p ⫽ 0.023); and maximum motor block levels were 3.00 ⫾ 0.00, 2.93 ⫾ 0.25 and 3.00 ⫾ 0.00, respectively (p ⫽ 0.37). Regression time of sensorial block to the L1 dermatome was significantly longer in Group III (p ⫽ 0.036). Time to the first analgesic requirement was significantly longer in Group III than the others (p ⫽ 0.026). The incidence of pruritis was significantly higher in Group III (p ⫽ 0.019). Conclusion: In conclusion, the addition of fentanyl to hyperbaric bupivacaine in spinal anaesthesia has dose dependent effect on increasing of the duration of analgesia, but it has also increased the incidence of side effects.
References 1. Anesth Analg. 2000;91:1452-1456. 2. Can J Anaesth. 42:987-991, 1995.
Posters
•
Central Nerve Blocks IV
171. The effects of intrathecal fentanyl in transurethral resection of prostat syndrome surgery under spinal anaesthesia Ozgurel O Department of Anaesthesiology, Akdeniz University, Antalya, Turkey Background and goal of study: The purpose of this study was to investigate the effects of adding intrathecal fentanyl to low dose hyperbaric bupivacaine in transurethral resection of prostat syndrome surgery. Material and methods: Forty-five patients were randomly allocated into three groups of 15. Spinal anaesthesia was performed between L3-4 interspace with a 25 G spinal needle in the left lateral position. In Group 1, intrathecal 10 mg hyperbaric bupivacaine 0.5% in 3 ml; in Group 2, 10 mg hyperbaric bupivacaine 0.5% ⫹ 12.5 micg fentanyl in 3 ml, and in Group 3, 10 mg hyperbaric bupivacaine 0.5% ⫹ 25 micg fentanyl in 3 ml were administered. Patients were taken to litotomy position after keeping them in the supine for 10 minutes. Maximum sensorial and motor block levels, regression time of sensorial block to the L1 dermatome, time to the first analgesic requirement during the postoperative period, side effects and complications were recorded. Results and discussion: Maximum sensorial block levels were significantly higher in group III than those in other groups (9.13 ⫾ 1.59, 9.46 ⫾ 1.06, and 7.73 ⫾ 1.75, respectively; p ⫽ 0.023); and maximum motor block levels were 3.00 ⫾ 0.00, 2.93 ⫾ 0.25 and 3.00 ⫾ 0.00, respectively (p ⫽ 0.37). Regression time of sensorial block to the L1 dermatome was significantly longer in Group III (p ⫽ 0.036). Time to the first analgesic requirement was significantly longer in Group III than the others (p ⫽ 0.026). The incidence of pruritis was significantly higher in Group III (p ⫽ 0.019). Conclusion: In conclusion, the addition of fentanyl to hyperbaric bupivacaine in spinal anaesthesia has dose dependent effect on increasing of the duration of analgesia, but it has also increased the incidence of side effects.
References 1. Anesth Analg. 2000;91:1452-1456. 2. Can J Anaesth. 42:987-991, 1995.