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The effects of micro direct current electric stimulation on the enhancement of bone density and osseointegration
024-B2 Distraction osteogenesis and BMP osis by giving low calcium food to 14-week-old wister rats and observed serial changes in bone mineral density in the mandible, maxillary body, femur, and the spine. The mandible showed lower bone mineral density than the other bones.
14. Bone Apposition along Thin Ca-P Composite Films Prepared by the Ion:Beam Assisted Sputter Deposition Method
139
plants and P-rich Ca-P-IBASD implants, which was not seen around the control. It was also noted that there were no signs of released particles along the IBASD-coated implants. The histomorphometric results showed that there was statistically higher bone contact in the [3-TCP-IBASD specimens (70.2+-4.2%) as compared with the control (41.6_+ 14.9%, P = 0.01, Student t-test). In contrast, there was no statistically significant difference between P-rich Ca-P-IBASD specimens (64.9 +- 16.1%) and the c0ntrol(47.7-+ 20.1, P = 0.13, Student t-test). In conclusion, the present study showed that more bone was found adjacent to 13-TCP-IBASD implants as compared with the control after 12 weeks in rabbit tibiae.
Tsuboi, y1,2, Sennerby, L. 1, Johansson, C), Albrektsson, T.1, Ektessabi, A. M. 3, lizuka, T.2 IDepartment of Biomaterials/Handicap Research, Institute for Surgical Sciences, Gothenburg Univ., Sweden, 2Department of OMS, Graduate School of Medicine, Kyoto Univ., 3Department of Precision Engineering, Graduate School of Engineering, Kyoto Univ., Japan
15. The Effects of Micro Direct Current Electric Stimulation on the Enhancement of Bone Density and Osseointegration Yoo, J. S., Kim, S. K.
Departmen,t of Oral and Maxillofacial Surgery, College of Dentistry, Seoul National University, Seoul, Korea The aim of the present study was to investigate the bone apposition along thin HAP-like Ca-P composite films prepared by ion-beam assisted sputter deposition (IBASD). In this study, two types of Ca-P composite films with a thickness of 0.3 gm were coated on Cp-Ti cylindrical implants by using the IBASD method. The targets for the IBASD treatment were f3-TCP and P-rich Ca-P composite materials. The film compositions of the [3-TCP-IBASD implants and Prich-Ca-P-IBASD implants were analyzed by PIXE, RBS, and E R D and were found to be Ca10P5.7023.5H10.3 and Ca10P10.6034.4H5.6, respectively. The implants were inserted into both tibiae of five rabbits. Uncoated Cp-Ti implants were used as the control. All implants were retrieved en bloc and immediately immersed in 4% formalin for fixation 12 weeks after implant insertion. The specimens were embedded in light-curing resin, ground-sectioned to about 10 gm thickness, and stained with toluidine blue. By using Leitz microscopy with a Microvid computer, bone apposition along the implant surface was observed and the length of bone contact with the implants was measured at the cortical passage. Qualitative analysis revealed that an "osteocyte-rich" bone was present adjacent to the [3-TCP-IBASD im-
Successful osseointegration of titanium dental implants is decreased in areas of poor bone density. Electrical stimulation has been shown to perturb cells, which in turn promotes bone growth. The purpose of this study was to evaluate the effect of micro direct current electric stimulation on the bone density and osseointegration of implants. Both sides of the tibia of 12 matured, white rabbits were prepared for implantation. An 15 gA electric current stimulation was performed at the experimental side. Microscopic, radiologic and biomechanical examinations revealed that: 1. Active new bone formation and early calcification occurred at the test side. 2. Enhancement of bone density was seen (Bone Mineral Density), using Dural Energy X-ray Absorptiometry and Digital X-ray analysis system. 3. Micro Current Electric Stimulation, which was done before implantation, had more effect on the enhancement of bone density and osseointegration than electric stimulation after implantation.
14. Bone Apposition along Thin Ca-P Composite Films Prepared by the Ion:Beam Assisted Sputter Deposition Method
139
plants and P-rich Ca-P-IBASD implants, which was not seen around the control. It was also noted that there were no signs of released particles along the IBASD-coated implants. The histomorphometric results showed that there was statistically higher bone contact in the [3-TCP-IBASD specimens (70.2+-4.2%) as compared with the control (41.6_+ 14.9%, P = 0.01, Student t-test). In contrast, there was no statistically significant difference between P-rich Ca-P-IBASD specimens (64.9 +- 16.1%) and the c0ntrol(47.7-+ 20.1, P = 0.13, Student t-test). In conclusion, the present study showed that more bone was found adjacent to 13-TCP-IBASD implants as compared with the control after 12 weeks in rabbit tibiae.
Tsuboi, y1,2, Sennerby, L. 1, Johansson, C), Albrektsson, T.1, Ektessabi, A. M. 3, lizuka, T.2 IDepartment of Biomaterials/Handicap Research, Institute for Surgical Sciences, Gothenburg Univ., Sweden, 2Department of OMS, Graduate School of Medicine, Kyoto Univ., 3Department of Precision Engineering, Graduate School of Engineering, Kyoto Univ., Japan
15. The Effects of Micro Direct Current Electric Stimulation on the Enhancement of Bone Density and Osseointegration Yoo, J. S., Kim, S. K.
Departmen,t of Oral and Maxillofacial Surgery, College of Dentistry, Seoul National University, Seoul, Korea The aim of the present study was to investigate the bone apposition along thin HAP-like Ca-P composite films prepared by ion-beam assisted sputter deposition (IBASD). In this study, two types of Ca-P composite films with a thickness of 0.3 gm were coated on Cp-Ti cylindrical implants by using the IBASD method. The targets for the IBASD treatment were f3-TCP and P-rich Ca-P composite materials. The film compositions of the [3-TCP-IBASD implants and Prich-Ca-P-IBASD implants were analyzed by PIXE, RBS, and E R D and were found to be Ca10P5.7023.5H10.3 and Ca10P10.6034.4H5.6, respectively. The implants were inserted into both tibiae of five rabbits. Uncoated Cp-Ti implants were used as the control. All implants were retrieved en bloc and immediately immersed in 4% formalin for fixation 12 weeks after implant insertion. The specimens were embedded in light-curing resin, ground-sectioned to about 10 gm thickness, and stained with toluidine blue. By using Leitz microscopy with a Microvid computer, bone apposition along the implant surface was observed and the length of bone contact with the implants was measured at the cortical passage. Qualitative analysis revealed that an "osteocyte-rich" bone was present adjacent to the [3-TCP-IBASD im-
Successful osseointegration of titanium dental implants is decreased in areas of poor bone density. Electrical stimulation has been shown to perturb cells, which in turn promotes bone growth. The purpose of this study was to evaluate the effect of micro direct current electric stimulation on the bone density and osseointegration of implants. Both sides of the tibia of 12 matured, white rabbits were prepared for implantation. An 15 gA electric current stimulation was performed at the experimental side. Microscopic, radiologic and biomechanical examinations revealed that: 1. Active new bone formation and early calcification occurred at the test side. 2. Enhancement of bone density was seen (Bone Mineral Density), using Dural Energy X-ray Absorptiometry and Digital X-ray analysis system. 3. Micro Current Electric Stimulation, which was done before implantation, had more effect on the enhancement of bone density and osseointegration than electric stimulation after implantation.