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The function of the left atrium in hypertensive patients
110 economic level. The prevalence of associated cardiovascular risk factors was high: 10% for diabetes, 9% for dyslipidemia, 24% for obesity and 25% for smoking. Half of hypertensive subjects were aware of having hypertension, among them 96% were receiving treatment. Conclusion the prevalence of hypertension was high in 2009 in this cohort of Tunisian population. As primary prevention, it is important to consider lifestyle modification of the Tunisian people in order to reduce this cardiovascular risk factor. Also, screening for hypertension and improving access to health must be established in order to reduce the burden of this cardiovascular risk factor. Disclosure of interest The authors declare that they have no competing interest. https://doi.org/10.1016/j.acvdsp.2017.11.223 095
The function of the left atrium in hypertensive patients M. Ztati 1,∗ , L. Bendriss 2 , A. Elkhatouri 2 Cardiologie, CHU Mohamed VI 2 HMA CHU Mohamed VI, Marrakech, Morocco ∗ Corresponding author. E-mail address: [email protected] (M. Ztati)
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Introduction It has been established that the volume of OG is a marker of alteration of the diastolic function of the left ventricle. The aim of this study is to determine the relationship between left atrium remodeling and left ventricle diastolic dysfunction in hypertensive patients with preserved systolic function and the repercussions of high blood pressure (HTA) on size and function OG. Materials and methods A prospective study of 200 hypertensive patients in the cardiology department of the Avicenne military hospital in Marrakech during the period from July 2015 to July 2016. Results The average age of hypertensuve patients was 52 ± 5 years, 80 men, whose data were all evaluated by echocardiography measuring left atrium volumes during the reservoir, conduit and pump phases. Standard indices reflecting left ventricular filling were also assessed. Medium left atrium volume indexed for body surface was significantly higher in hypertensive patients—32.1 ± 4.6 mL/m2 vs.21.72 (2.52) mL/m2 . When compared to normal subjects, patients with mild diastolic dysfunction had lower corrected passive emptying volumes (P < 0.001) and higher corrected active emptying volumes, thus leading to similar corrected total emptying volumes (P < 0.001). However, patients with moderate diastolic dysfunction had smaller active emptying volumes, but higher passive and total emptying volumes when compared to normal controls and patients with mild diastolic dysfunction. Conclusion The HTA induces an increase in the pump function and the reservoir function and an alteration of the function of the OG; these changes appear to be related to left ventricular hypertrophy and the degree of left ventricular diastolic dysfunction. Disclosure of interest The authors declare that they have no competing interest. https://doi.org/10.1016/j.acvdsp.2017.11.224 068
Orthostatic hypotension in hypertensive patients: About 200 cases I. Hendy ∗ , A. Zbitou , A. Chatoui , A. Rbaibi , L. Bendriss , A. Khatouri Cardiologie, hôpital militaire Avicenne, Marrakech, Morocco ∗ Corresponding author. E-mail address: [email protected] (I. Hendy)
06-Arterial hypertension and vascular disease Introduction Orthostatic hypotension is common in hypertensive patients. It’s a poor prognostic factor and an independent marker of cardiovascular mortality. Purpose Studying the prevalence of orthostatic hypotension in hypertensive patients followed and its risk factors. Methods This is a prospective epidemiological study conducted within the Avicenna military hospital from January 2015 to august 2015. We included patients randomly selected from the hypertension consultation. The statistical analysis was done using SPSS software V10. We recorded a total of 200 patients. The average age was 62.2 years old. The sex ratio was 1.5 in favor of female sex. 31 patients were known to have diabetes (15.5%), 80% of our patients had a well-controlled hypertension, 35% were smokers and 24% had dyslipidemia. A total of 20 patients (10%) had a history of stroke and 9 of myocardial infarction. Results The prevalence of orthostatic hypotension in our patients was 10%, 60% of them were symptomatic. Eighty percent of the cases were over 60 years old with no significant gender difference. The prevalence in diabetic patients was 38% with a positive correlation between orthostatic hypotension and glycemic control. We found a positive correlation between the orthostatic hypotension and the hypertension grade (17.1% grade III, 9.4% grade II, 7.1% grades I), 80% in orthostatic hypotension cases were poorly balanced in terms of blood pressure. Orthostatic hypotension was more frequent in patient under triple therapy (50%). In multivariate analysis, factors independently related to orthostatic hypotension were: advanced age, diabetes, triple therapy and stroke. Conclusion Orthostatic hypotension is commonly associated with hypertension and remains under diagnosed due to the frequency of asymptomatic forms. It’s a factor of mortality and poor therapeutic adherence, so a systematic screening is justified in all hypertensive patients. Disclosure of interest The authors declare that they have no competing interest. https://doi.org/10.1016/j.acvdsp.2017.11.225 420
Echocardiographic left atrial remodelling in the early phase of high blood pressure and its correlation with microalbuminuria: A case control study in sub Saharan Africans A. Dzudie-Tamdja 1,2 , C. Simo-Gounoue 3,∗ , S.-P. Choukem 3 , A. Nzali 4 , C. Nkoke 5 , S. Mouliom 1 , C. Nganou 2 , M.P. Halle 1 , S. Kingue 2 1 Hopital General de Douala, Douala 2 Cardiology department, faculty of medecine and biomedical sciences University of Yaounde 1 3 Faculty of health sciences Universityof Buea, Buea 4 Deido district hospital, Douala, Cameroon 5 Cardiology department, Buea regional hospital, Buea, Bulgary ∗ Corresponding author. E-mail address: corrine [email protected] (C. Simo-Gounoue) Background Left atrial remodelling (LAR) is a common finding in patients with chronic hypertension and increases the risk of adverse cardiovascular events. However, early changes in the left atrial size and association microalbuminuria are poorly elucidated. Objective To assess early left atrial structural remodelling in hypertensive patients and determine its correlation with microalbuminuria. Methodology Fifty-two patients diagnosed with hypertension for less than a year were matched for age sex to forty healthy controls. Patients with pre-existing, cardiovascular disease, kidney disease and diabetes were excluded. The left atrial endocardial border was traced to get atrial length, transverse diameter, surface area and volume while the anteroposterior diameter was obtained on the
The function of the left atrium in hypertensive patients M. Ztati 1,∗ , L. Bendriss 2 , A. Elkhatouri 2 Cardiologie, CHU Mohamed VI 2 HMA CHU Mohamed VI, Marrakech, Morocco ∗ Corresponding author. E-mail address: [email protected] (M. Ztati)
1
Introduction It has been established that the volume of OG is a marker of alteration of the diastolic function of the left ventricle. The aim of this study is to determine the relationship between left atrium remodeling and left ventricle diastolic dysfunction in hypertensive patients with preserved systolic function and the repercussions of high blood pressure (HTA) on size and function OG. Materials and methods A prospective study of 200 hypertensive patients in the cardiology department of the Avicenne military hospital in Marrakech during the period from July 2015 to July 2016. Results The average age of hypertensuve patients was 52 ± 5 years, 80 men, whose data were all evaluated by echocardiography measuring left atrium volumes during the reservoir, conduit and pump phases. Standard indices reflecting left ventricular filling were also assessed. Medium left atrium volume indexed for body surface was significantly higher in hypertensive patients—32.1 ± 4.6 mL/m2 vs.21.72 (2.52) mL/m2 . When compared to normal subjects, patients with mild diastolic dysfunction had lower corrected passive emptying volumes (P < 0.001) and higher corrected active emptying volumes, thus leading to similar corrected total emptying volumes (P < 0.001). However, patients with moderate diastolic dysfunction had smaller active emptying volumes, but higher passive and total emptying volumes when compared to normal controls and patients with mild diastolic dysfunction. Conclusion The HTA induces an increase in the pump function and the reservoir function and an alteration of the function of the OG; these changes appear to be related to left ventricular hypertrophy and the degree of left ventricular diastolic dysfunction. Disclosure of interest The authors declare that they have no competing interest. https://doi.org/10.1016/j.acvdsp.2017.11.224 068
Orthostatic hypotension in hypertensive patients: About 200 cases I. Hendy ∗ , A. Zbitou , A. Chatoui , A. Rbaibi , L. Bendriss , A. Khatouri Cardiologie, hôpital militaire Avicenne, Marrakech, Morocco ∗ Corresponding author. E-mail address: [email protected] (I. Hendy)
06-Arterial hypertension and vascular disease Introduction Orthostatic hypotension is common in hypertensive patients. It’s a poor prognostic factor and an independent marker of cardiovascular mortality. Purpose Studying the prevalence of orthostatic hypotension in hypertensive patients followed and its risk factors. Methods This is a prospective epidemiological study conducted within the Avicenna military hospital from January 2015 to august 2015. We included patients randomly selected from the hypertension consultation. The statistical analysis was done using SPSS software V10. We recorded a total of 200 patients. The average age was 62.2 years old. The sex ratio was 1.5 in favor of female sex. 31 patients were known to have diabetes (15.5%), 80% of our patients had a well-controlled hypertension, 35% were smokers and 24% had dyslipidemia. A total of 20 patients (10%) had a history of stroke and 9 of myocardial infarction. Results The prevalence of orthostatic hypotension in our patients was 10%, 60% of them were symptomatic. Eighty percent of the cases were over 60 years old with no significant gender difference. The prevalence in diabetic patients was 38% with a positive correlation between orthostatic hypotension and glycemic control. We found a positive correlation between the orthostatic hypotension and the hypertension grade (17.1% grade III, 9.4% grade II, 7.1% grades I), 80% in orthostatic hypotension cases were poorly balanced in terms of blood pressure. Orthostatic hypotension was more frequent in patient under triple therapy (50%). In multivariate analysis, factors independently related to orthostatic hypotension were: advanced age, diabetes, triple therapy and stroke. Conclusion Orthostatic hypotension is commonly associated with hypertension and remains under diagnosed due to the frequency of asymptomatic forms. It’s a factor of mortality and poor therapeutic adherence, so a systematic screening is justified in all hypertensive patients. Disclosure of interest The authors declare that they have no competing interest. https://doi.org/10.1016/j.acvdsp.2017.11.225 420
Echocardiographic left atrial remodelling in the early phase of high blood pressure and its correlation with microalbuminuria: A case control study in sub Saharan Africans A. Dzudie-Tamdja 1,2 , C. Simo-Gounoue 3,∗ , S.-P. Choukem 3 , A. Nzali 4 , C. Nkoke 5 , S. Mouliom 1 , C. Nganou 2 , M.P. Halle 1 , S. Kingue 2 1 Hopital General de Douala, Douala 2 Cardiology department, faculty of medecine and biomedical sciences University of Yaounde 1 3 Faculty of health sciences Universityof Buea, Buea 4 Deido district hospital, Douala, Cameroon 5 Cardiology department, Buea regional hospital, Buea, Bulgary ∗ Corresponding author. E-mail address: corrine [email protected] (C. Simo-Gounoue) Background Left atrial remodelling (LAR) is a common finding in patients with chronic hypertension and increases the risk of adverse cardiovascular events. However, early changes in the left atrial size and association microalbuminuria are poorly elucidated. Objective To assess early left atrial structural remodelling in hypertensive patients and determine its correlation with microalbuminuria. Methodology Fifty-two patients diagnosed with hypertension for less than a year were matched for age sex to forty healthy controls. Patients with pre-existing, cardiovascular disease, kidney disease and diabetes were excluded. The left atrial endocardial border was traced to get atrial length, transverse diameter, surface area and volume while the anteroposterior diameter was obtained on the