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The Genetics of Cancer
Libri
Biomed & Pharmacother 1997;51:140 © Elsevier, Paris
Immunology. Fourth Edition. I Roitt, J Brostoff, D Male, eds. Mosby, London, 1995. This 4th edition constitutes the best texbook for students of both science and medicine. Its concise, comprehensible text and conceptual diagrams make immunologic mechanisms clear to any student. This edition provides the most lucid and up-to-date coverage of immunology available. Conceptual, color artwork on every page enables to comprehend this difficult subject, not just memorize isolated facts. The chapter objectives provided at the start of each chapter help to focus efforts, and will serve as a great review tool before exams. Paragraph headings provide a summary of the following details, ensuring that the reader takes in the most important information at every stage, and will be particularly useful during exam preparation. Critical thinking boxes are included at the end of each chapter. These encourage the student to think about the information he has just read, ensuring that his understanding is complete and integrated into the whole framework of immunology. Concise text and small chapters enable to learn the subject without becoming overwhelmed. Glossary of terms includes the many new words and phrases that will be encountered during this course, now even more comprehensive than in previous editions.
The Genetics of Cancer. BAJ Ponder, MJ Waring, Kluwer Academic Publishers, Dordrecht/Boston/London, 1995. It has been recognized for almost 200 years that certain families seem to inherit cancer. It is only in the past decade, however, that molecular genetics and epidemiology have combined to define the role of inheritance in cancer more clearly, and to identify some of the genes involved. The causative genes can be tracked through cancer-prone families via genetic linkage and positional cloning. Several of the genes discovered have subsequently been proven to play critical roles in normal growth and development. There are also implications for the families themselves in terms of genetic testing with its attendant dilemmas, if it is not clear that useful action will result.
The chapters in The Genetics of Cancer illustrate what has already been achieved and take a critical look at the future directions of this research and its potential clinical applications.
Guidebook on Molecular Modeling in Drug Design. N Claude Cohen. Academic Press, San Diego/New York/Boston/London/Sydney/Tokyo/Toronto, 1996. Molecular modeling has assumed an important role in understanding the three-dimensional aspects of specificity in drug-receptor interactions at the molecular level. Well-established in pharmaceutical research, molecular modeling offers unprecedented opportunities for assisting medicinal chemists in the design of new therapeutic agents. Advances made in computer hardware and in theoretical medicinal chemistry have brought high-performance computing and graphics tools within the reach of most academic and industrial laboratories, and permitted the development of new approaches to rational drug design. The Guidebook on Molecular Modeling in Drug Design serves as a manual for the analysis of the molecular structure of biological molecules and drugs and the correlation of these structures with pharmacological actions. Intended as a guide to the capabilities of computer-assisted modeling in drug design and discovery for advanced students and professionals, this book will be of interest to medicinal and organic chemists, pharmaceutical researchers, pharmacologists, and biochemists who want to gain further insight into this rapidly advancing field.
Books received DNA and RNA Cleavers and Chemotherapy of Cancer and Viral Diseases. B Meunier. Kluwer Academic Publishers, Dordrecht/Boston/London, 1996.
Drug-Induced Hepatotoxicity. RG Cameron, G Geuer, FA de la Iglesia. Springer Verlag, Berlin/Heidelberg/New York/London/Paris/Tokyo/Hong Kong/Barcelona/Budapest, ! 996.
Biomed & Pharmacother 1997;51:140 © Elsevier, Paris
Immunology. Fourth Edition. I Roitt, J Brostoff, D Male, eds. Mosby, London, 1995. This 4th edition constitutes the best texbook for students of both science and medicine. Its concise, comprehensible text and conceptual diagrams make immunologic mechanisms clear to any student. This edition provides the most lucid and up-to-date coverage of immunology available. Conceptual, color artwork on every page enables to comprehend this difficult subject, not just memorize isolated facts. The chapter objectives provided at the start of each chapter help to focus efforts, and will serve as a great review tool before exams. Paragraph headings provide a summary of the following details, ensuring that the reader takes in the most important information at every stage, and will be particularly useful during exam preparation. Critical thinking boxes are included at the end of each chapter. These encourage the student to think about the information he has just read, ensuring that his understanding is complete and integrated into the whole framework of immunology. Concise text and small chapters enable to learn the subject without becoming overwhelmed. Glossary of terms includes the many new words and phrases that will be encountered during this course, now even more comprehensive than in previous editions.
The Genetics of Cancer. BAJ Ponder, MJ Waring, Kluwer Academic Publishers, Dordrecht/Boston/London, 1995. It has been recognized for almost 200 years that certain families seem to inherit cancer. It is only in the past decade, however, that molecular genetics and epidemiology have combined to define the role of inheritance in cancer more clearly, and to identify some of the genes involved. The causative genes can be tracked through cancer-prone families via genetic linkage and positional cloning. Several of the genes discovered have subsequently been proven to play critical roles in normal growth and development. There are also implications for the families themselves in terms of genetic testing with its attendant dilemmas, if it is not clear that useful action will result.
The chapters in The Genetics of Cancer illustrate what has already been achieved and take a critical look at the future directions of this research and its potential clinical applications.
Guidebook on Molecular Modeling in Drug Design. N Claude Cohen. Academic Press, San Diego/New York/Boston/London/Sydney/Tokyo/Toronto, 1996. Molecular modeling has assumed an important role in understanding the three-dimensional aspects of specificity in drug-receptor interactions at the molecular level. Well-established in pharmaceutical research, molecular modeling offers unprecedented opportunities for assisting medicinal chemists in the design of new therapeutic agents. Advances made in computer hardware and in theoretical medicinal chemistry have brought high-performance computing and graphics tools within the reach of most academic and industrial laboratories, and permitted the development of new approaches to rational drug design. The Guidebook on Molecular Modeling in Drug Design serves as a manual for the analysis of the molecular structure of biological molecules and drugs and the correlation of these structures with pharmacological actions. Intended as a guide to the capabilities of computer-assisted modeling in drug design and discovery for advanced students and professionals, this book will be of interest to medicinal and organic chemists, pharmaceutical researchers, pharmacologists, and biochemists who want to gain further insight into this rapidly advancing field.
Books received DNA and RNA Cleavers and Chemotherapy of Cancer and Viral Diseases. B Meunier. Kluwer Academic Publishers, Dordrecht/Boston/London, 1996.
Drug-Induced Hepatotoxicity. RG Cameron, G Geuer, FA de la Iglesia. Springer Verlag, Berlin/Heidelberg/New York/London/Paris/Tokyo/Hong Kong/Barcelona/Budapest, ! 996.