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The immediate prognosis of congestive heart failure
SELECTED
137
ABSTRACT’S
to the media, or more superficially, near the endothelium. they are surrounded by chronic inflammatory changes.
In the majority
of cases
Hemorrhage from these sinusoids is a not uncommon finding in coronary atherosclerosis. Hemorrhages into the deeper zones of the intima heal by granulation tissue Such a process increases the fibrosis and in. which new capillaries are numerous. the vascularity of the intima and predisposes it to further hemorrhage. Superficial intimal hemorrhage is a most coronary occlusion. It was present in eleven in nine of these, thrombotic occlusion of the
important factor in the etiology of seventeen patients examined, lumen was also present.
The factors determining the intimal hemorrhage are probably sinusoidal wall by toxic action and transient raised intraluminar In such cases superimposed intravascular by exertion or emotion. delayed until a subsequent period of bodily or mental rest.
weakening pressure thrombosis
of but,
of the induced may be AUTHOR.
Boyer, N. II., Leach, C. E., and White, P. D.: The Immediate gestive Heart Failure. Ann. Int. Med. 14: 2210, 1941.
Prognosis
of Con-
The immediate prognosis in 748 patients with congestive heart failure has been studied and found, in general, to depend very little on the underlying type on the precipitating cause of failure, of heart disease, but, in varying degree, the patient’s age, the degree of clinical cardiac enlargement, and the presence or absence of complications. An additional analysis of the case histories of seventy-seven known hypertensive patients and ninety known nonhypertensive patients with coronary thrombosis revealed that a greater percentage of hypertensive patients will develop congestive heart failure than will the nonhypertensive, and consequently the prognosis is poorer for the former group of patients when coronary occlusion occurs. Once failure develops, however, the outcome is the same for those with or without antecedent hypertension. AUTHORS.
Crafoord, J. A. M.
C., ‘and Jorpes, E.: A. 116:
2831,
In 325 cases involving thromboembolie complications such complications occurred The mitted urinary
Heparin
as a Prophylactic
Against
Thrombosis.
1941. postoperative did not arise. in 9 per cent.
treatment with heparin, symptoms of In a Pontrol series of 1,111 similar cases
patients selected were in both series over thirty-five years to operations on the gastrointestinal tract, the biliary passages or to major operations for hernia and varices.
of age and subsystem or the
Reference is made to another series of eighty-eight patients with gynecologic disorders operated on for myoma or prolapsus uteri without any thromboembolic complications. In the control series of 1,054 cases there were complications in 4 per cent. The heparin used had a strength of about 70 per cent of the pure mucoitin trisulfuric acid. It was given as a 5 per cent sterile solution in intermittent intravenous injections four times a day. The ordinary dose was 50 plus 50 plus 50 plus 100 (or 75 plus 75 plus 75 plus 125) mg. daily, started four hours after the operation. The treatment was continued for five to ten days. AUTHORS.
137
ABSTRACT’S
to the media, or more superficially, near the endothelium. they are surrounded by chronic inflammatory changes.
In the majority
of cases
Hemorrhage from these sinusoids is a not uncommon finding in coronary atherosclerosis. Hemorrhages into the deeper zones of the intima heal by granulation tissue Such a process increases the fibrosis and in. which new capillaries are numerous. the vascularity of the intima and predisposes it to further hemorrhage. Superficial intimal hemorrhage is a most coronary occlusion. It was present in eleven in nine of these, thrombotic occlusion of the
important factor in the etiology of seventeen patients examined, lumen was also present.
The factors determining the intimal hemorrhage are probably sinusoidal wall by toxic action and transient raised intraluminar In such cases superimposed intravascular by exertion or emotion. delayed until a subsequent period of bodily or mental rest.
weakening pressure thrombosis
of but,
of the induced may be AUTHOR.
Boyer, N. II., Leach, C. E., and White, P. D.: The Immediate gestive Heart Failure. Ann. Int. Med. 14: 2210, 1941.
Prognosis
of Con-
The immediate prognosis in 748 patients with congestive heart failure has been studied and found, in general, to depend very little on the underlying type on the precipitating cause of failure, of heart disease, but, in varying degree, the patient’s age, the degree of clinical cardiac enlargement, and the presence or absence of complications. An additional analysis of the case histories of seventy-seven known hypertensive patients and ninety known nonhypertensive patients with coronary thrombosis revealed that a greater percentage of hypertensive patients will develop congestive heart failure than will the nonhypertensive, and consequently the prognosis is poorer for the former group of patients when coronary occlusion occurs. Once failure develops, however, the outcome is the same for those with or without antecedent hypertension. AUTHORS.
Crafoord, J. A. M.
C., ‘and Jorpes, E.: A. 116:
2831,
In 325 cases involving thromboembolie complications such complications occurred The mitted urinary
Heparin
as a Prophylactic
Against
Thrombosis.
1941. postoperative did not arise. in 9 per cent.
treatment with heparin, symptoms of In a Pontrol series of 1,111 similar cases
patients selected were in both series over thirty-five years to operations on the gastrointestinal tract, the biliary passages or to major operations for hernia and varices.
of age and subsystem or the
Reference is made to another series of eighty-eight patients with gynecologic disorders operated on for myoma or prolapsus uteri without any thromboembolic complications. In the control series of 1,054 cases there were complications in 4 per cent. The heparin used had a strength of about 70 per cent of the pure mucoitin trisulfuric acid. It was given as a 5 per cent sterile solution in intermittent intravenous injections four times a day. The ordinary dose was 50 plus 50 plus 50 plus 100 (or 75 plus 75 plus 75 plus 125) mg. daily, started four hours after the operation. The treatment was continued for five to ten days. AUTHORS.