OOOO Volume 129, Number 1 of chromosome 6 p21, whose function is the differentiation of osteoblasts. Evidence suggests that this gene also acts in the participation of odontoblasts differentiation. The main clinical alterations are short stature, enlarged head, prolonged retention of deciduous teeth, delayed eruption of permanents, and presence of innumerable supernumeraries. The objective of this study is to report the diagnosis of cleidocranial dysplasia in a 4-year-old female patient with light brown skin color in a family health unit. The main clinical findings were prominence of the frontal and parietal bosses, ocular hypertelorism, and depressed nasal bridge and shoulders with hypermobility. The imaging examinations showed clavicular hypoplasia and changes in tarsal bones without major abnormalities in facial radiograph.
DIFFUSE LARGE B-CELL LYMPHOMA OF THE MENTAL REGION. THAYSA BARBOSA DOS SANTOS QUEIROZ, SARAH APARECIDA FERREIRA ANTERO, RAFAELA DA SILVA GONCALVES ¸ BEZERRA, ALEXANDRE MAURITY DE e PAULA AFONSO, JULLY GUIMARAES DE OLIVEIRA ANTUNES, BRUNO AUGUSTO BENEVENUTO DE e ANDRADE and, MARIO JOSE ROMANACH Diffuse large B-cell lymphoma (DLBCL) is an aggressive type of non-Hodgkin lymphoma. A 38-year-old male patient was referred presenting an exuberant, asymptomatic, and reddish swelling in the mental region of the face, with progressive growth for the last 3 months. Intraoral examination revealed an ulcerated nodule in the lower anterior vestibule, which produced slight resorption of the buccal bone cortical of the anterior mandible and displacement of anterior teeth. Intraoral incisional biopsy was performed, and microscopic examination revealed proliferation of atypical large lymphoid cells, which were immunopositive for CD20, PAX-5, BCL-6, MUM-1, CD30, and Ki-67 (90%) and negative for CD3 and CD10. The final diagnosis was DLBCL. The patient is under follow-up after the first cycle of chemotherapy, and the tumor has decreased totally in size. DLBCL may appear as a reddish swelling of the face with extension to the oral cavity.
THE IMPORTANCE OF DIFFERENTIAL DIAGNOSIS IN CASES OF NECROTIZING SIALOMETAPLASIA: A CASE REPORT. LORENA BATISTA SANDRE, GUILHERME HENRIQUE DIAS DA COSTA DANTAS, MARCONI GONZAGA TAVARES and, e ELIZIARIO CESAR DE VASCONCELOS LEITAO Necrotizing sialometaplasia (NS) is a rare benign disease characterized by a reactionary inflammatory process of salivary glands, which may mimic malignancy, creating diagnostic dilemma leading to unwarranted aggressive treatment. On the present report, a 51-year-old male patient without comorbidities who was a casual alcoholic and smoker for over 25 years sought care with complaint of a painful wound on the palate for 15 days. Intraoral examination revealed an ulcerated wound localized in the transition between hard and soft palate, measuring 2.5 cm, and rounded with friable necrotic tissue and well delimitated elevated borders. The initial diagnostic hypothesis was squamous cell carcinoma. Incisional biopsy was performed, and the histopathologic analysis revealed mixed inflammatory process, ulcerated, involving minor salivary glands with focus of squamous metaplasia. The final diagnosis was NS. The treatment was the quitting of smoking and monitoring of the case. After 60 days, there was regression of the wound compatible with cure.
ABSTRACTS
e95
AMELOBLASTOMA OF THE POSTERIOR MANDIBLE: DELAYED DIAGNOSIS DURING ORTHODONTIC TREATMENT. DANIELLA LUCENA MORAIS, ANA LUZIA ARAUJO e BATISTA, RAFAEL GROTTA GREMPEL, TIAGO JOAO DA SILVA FILHO, DANIELA PITA DE MELO, POLLIANNA MUNIZ ALVES and, CASSIANO FRANCISCO WEEGE NONAKA Ameloblastoma is a benign epithelial odontogenic neoplasm characterized by locally aggressive behavior. This lesion is often asymptomatic, and some cases are detected during routine radiographic examination. A 33-year-old female patient undergoing orthodontic treatment presented with a 1-month history of a painful swelling in the posterior mandible. Her medical history was noncontributory. Panoramic radiograph showed a well-defined, multilocular radiolucency on the left side of the mandible extending from tooth #37 to the mandibular ramus. A panoramic radiograph obtained for orthodontic documentation 7 years earlier revealed a well-defined, unilocular radiolucency associated with the crown of unerupted tooth #38. Under the diagnostic hypothesis of odontogenic keratocyst, an incisional biopsy was performed. Histopathologic findings confirmed the diagnosis of ameloblastoma. The patient was referred for surgical treatment and remains under close follow-up. This case emphasizes the importance of a detailed analysis of patient images, irrespective of the diagnostic goal, before any dental treatment planning.
LASER PHOTOCOAGULATION FOR THE TREATMENT OF VASCULAR LESION IN OROFACIAL REGION. DANIELLA LUCENA MORAIS, GUSTAVO GOMES AGRIPINO, ROBERIA LUCIA DE QUEIROZ FIGUEIREDO, ISABELLA JARDELINO DIAS, JOZINETE VIEIRA PEREIRA, CASSIANO FRANCISCO WEEGE NONAKA and, DALIANA QUEIROGA DE CASTRO GOMES A 53-year-old male patient presented with an approximately 8-year history of an asymptomatic "blood blister" on the lower lip. Extraoral examination revealed a soft, purplish, lobulated swelling on the left side of the lower lip skin. Intraoral examination showed a well-defined, purplish stain and papules on the left lower lip and alveolar mucosa, measuring approximately 1.5 £ 1.0 cm. The diagnostic hypothesis was vascular lesion, which was later confirmed by a positive diascopy result. Under local anesthesia, the patient was submitted to 2 clinical sessions of photocoagulation with high-intensity diode laser (Thera Lase Surgery; 808»830 nm § 20 nm, 2.5 W, defocused 2 mm beam in continuous mode). The postoperative course was uneventful. After 6 months of follow-up, the patient reported only mild sensitivity in the region. Clinical examination revealed fibrosis compatible with the tissue repair process without aesthetic or functional impairment.
ORAL MANIFESTATIONS IN LANGERHANS CELL HISTIOCYTOSIS. A CASE REPORT. PILAR GANDARA-VILA, CATALINA BARBAe MONTERO, JOSE MANUEL SUAREZ-PENARANDA, JOSE MANUEL SOMOZA-MARTIN, ABEL GARCIAGARCIA, ANDRES BLANCO-CARRION and, MARIO PEREZ-SAYANS We present a case of a 68-year-old woman diagnosed as having multisystem Langerhans cell histiocytosis (LCH) 8 years ago.