THE KING AMONG THE SURGEONS

THE KING AMONG THE SURGEONS

378 " XBD=2553 XBD=1476 XHG=2476 XBD=1537 XBD=1896 XBD=1992 XBD=2312 XBD=2370 XBD=2456 XHG=1372 YBD=232 XHG=1497 XHG=1558 XHG=1916 XHG=2013 XHG=2332 ...

212KB Sizes 4 Downloads 55 Views

378

" XBD=2553 XBD=1476 XHG=2476 XBD=1537 XBD=1896 XBD=1992 XBD=2312 XBD=2370 XBD=2456 XHG=1372 YBD=232 XHG=1497 XHG=1558 XHG=1916 XHG=2013 XHG=2332 XHG=2390 YBD=233 YBD=242 YBD=241 YHG=203>tions YHG=202>of YHG=200>sulphaguanidine YHG=201>and YHG=200>sulphathiazole YHG=200>in YHG=200>the YHG=200>first Annotations

" XBD=2597 XBD=1598 XHG=2588 XBD=1718 XBD=1823 XBD=1964 XBD=2093 XBD=2167 XBD=2289 XBD=2424 XBD=2493 XBD=2556 XHG=1372 YBD=258 XHG=1604 XHG=1729 XHG=1834 XHG=1971 XHG=2102 XHG=2179 XHG=2296 XHG=2434 XHG=2502 YBD=286 YHG=240>.YBD=278 YBD=285 YBD=277 YBD=276 YHG=246>forty-eight YHG=247>hours YHG=255>were YHG=245>nearly YHG=245>equal, YHG=245>the YHG=254>mean YHG=244>values YHG=245>for YHG=245>six

"|>"XBD=2208 XBD=1626 XBD=1756 XBD=1856 XBD=1909 XBD=2015 XBD=2137 XBD=2555 XHG=1371 XHG=1644 XHG=1769 XHG=1870 XHG=1925 XHG=2025 XHG=2150 XHG=2223YBD=320 YBD=329 YBD=321 YBD=330 YBD=329YHG=290>for YHG=290>experiments YHG=289>being YHG=289>27% YHG=290>of YHG=290>dose YHG=290>given YHG=289>sulphaguanidine THE KING AMONG THE SURGEONS "|>"XBD=2557 XBD=1449 XBD=1699 XBD=2036 XBD=2132 XBD=2222 XBD=2360 XBD=2496 XBD=1612 XHG=1372 XHG=1640 XHG=1727 XHG=2062 XHG=2156 XHG=2247 XHG=2384 XHG=2520 XHG=1479YBD=365 YBD=374 YBD=364 YBD=374YHG=335>of YHG=333>and YHG=334>for YHG=333>sulphathiazole, YHG=333>but YHG=334>the YHG=333>blood YHG=333>levels YHG=334>25-8% " XBD=1308 XBD=249 XBD=473 XBD=548 XBD=646 XBD=755 XBD=956 XBD=1063 XBD=1223 XHG=164 XHG=285 XHG=507 XHG=583 XHG=678 XHG=992 XHG=1098 XHG=1258 YBD=405 YBD=410 YBD=405 YBD=406 YBD=407 YHG=376>THE YHG=375>luncheon YHG=375>at YHG=375>no. YHG=375>39,, YHG=374>Inn YHG=374>Fields YHG=385>on XBD=1712XHG=767 XBD=1819 XBD=1923 XBD=2020 XBD=2140 XBD=2192 XBD=2503 XBD=2554 XHG=1371YBD=406 XHG=1724 XHG=1833 XHG=1938 XHG=2031 XHG=2153 XHG=2208 XHG=2516 YBD=417YHG=374>Lincoln’s YBD=418 YBD=409 YHG=377>sulphaguanidine YHG=387>were YHG=377>only YHG=378>half YHG=378>those YHG=379>of YHG=377>sulphathiazole YHG=380>at total XBD=244 XBD=285 XBD=378 XBD=581 XBD=637 XBD=721 XBD=876 XBD=997 XBD=1055 XBD=1247 XBD=1308 XHG=115 XHG=265 XHG=301 XHG=396 XHG=598 XHG=655 XHG=738 XHG=892 XHG=1014 XHG=1071 XHG=1265 YBD=449 YBD=457 YBD=450 YBD=449 YBD=450 YHG=419>March YHG=421>8 YHG=428>was YHG=418>domestic YHG=418>in YHG=418>the YHG=427>proper YHG=427>sense YHG=418>of YHG=419>intimate YHG=428>or "|>"XBD=2555 XBD=1393 XBD=1648 XBD=1763 XBD=1965 XBD=2166 XBD=2354 XBD=2448 XBD=1879 XBD=2264 XHG=1370 XHG=1407 XHG=1669 XHG=1893 XHG=2090 XHG=2282 XHG=2372 XHG=2464 XHG=1780 XHG=2184 YBD=461 YBD=453 YBD=454 YBD=452 YBD=462 YBD=460 YBD=453 YHG=431>a YHG=422>comparable YHG=422>time YHG=423>mg. YHG=422>and YHG=431>mg. YHG=422>free YHG=421>drug YHG=422>(2’14 YHG=424>1-56 XBD=140 XBD=197 XBD=363 XBD=496 XBD=629 XBD=693 XBD=780 XBD=980 XBD=1156 XBD=1235 XBD=1307 XHG=118 XHG=155 XHG=213 XHG=416 XHG=515 XHG=652 XHG=714 XHG=802 XHG=1003 XHG=1175 XHG=1256 YBD=476 YBD=501 YBD=492 YBD=493 YBD=502 YBD=499 YBD=494 YHG=464>&dquo; YHG=464>at YHG=463>home.&dquo; YHG=461>The YHG=462>King, YHG=471>as YHG=461>the YHG=461>College’s YHG=462>Visitor, YHG=464>sat YHG=472>on "|>"XBD=2552 XBD=1436 XBD=1529 XBD=1643 XBD=1865 XBD=1977 XBD=2152 XBD=2274 XBD=2366 XBD=2056 XBD=2466 XHG=1368 XHG=1462 XHG=1549 XHG=1664 XHG=1884 XHG=2078 XHG=2175 XHG=2291 XHG=2483 XHG=1999 XHG=2385 YBD=504 YBD=505 YBD=497 YBD=496 YBD=506 YBD=497 YBD=496 YHG=474>per YHG=466>100 YHG=475>c.cm YHG=466>compared YHG=466>with YHG=466>total YHG=465>and YHG=475>mg. YHG=467>4-7 YHG=466>3-45 Smith XBD=181 XHG=783 XBD=422 XBD=552 XBD=637 XBD=766 XBD=822 XBD=1063 XBD=1128 XBD=1203 XBD=1302 XHG=114 XHG=196 XHG=438 XHG=571 XHG=654 XHG=845YBD=537 XHG=1079 XHG=1144 XHG=1220 YBD=545 YBD=536 YBD=537 YBD=537YHG=505>of YBD=542 YHG=506>the YHG=506>president’s YHG=505>right, YHG=505>the YHG=505>Duke YHG=505>Gloucester YHG=516>onhas YHG=506>his YHG=506>left, " XBD=2552 XBD=1473 XBD=1772 XBD=1963 XBD=2181 XBD=2227 XBD=2425 XHG=1367 XHG=1664 XHG=1795 XHG=1989 XHG=2205 XHG=2253 XHG=2450 YBD=540 YBD=550 YBD=548 YBD=541 YHG=501>free). YHG=509>4 YHG=510>recently YHG=510>described YHG=519>a YHG=509>series,of YHG=509>adult XBD=155 XBD=243 XBD=354 XBD=539 XBD=629 XBD=859 XBD=1029 XBD=1156 XBD=1218 XBD=1306 XBD=479XHG=650 XHG=114 XHG=177 XHG=265 XHG=501 XHG=562 XHG=882 XHG=1049 XHG=1178 XHG=1239 XHG=374YBD=581 YBD=589 YBD=580 YBD=581 YBD=586YHG=549>renovated YBD=581 YHG=550>at YHG=550>the YHG=549>long YHG=549>in YHG=549>the YHG=550>council YHG=549>table YHG=559>room YHG=550>of YHG=550>the "|>"XBD=2553 XBD=1576 XBD=1765 XBD=1937 XBD=2048 XBD=2422 XHG=1369 XHG=1597 XHG=1788 XHG=1956 XHG=2074 XHG=2443 YBD=585 YBD=595 YBD=593 YHG=552>dysentery YHG=554>patients YHG=554>treated YHG=554>with YHG=553>sulphaguanidine, YHG=562>many " XBD=1305 XBD=356 XBD=552 XBD=684 XBD=743 XBD=1089 XBD=1202 XHG=113 XHG=394 XHG=604 XHG=780 XHG=1126 XHG=1239 YBD=633 YBD=624 YBD=633 YBD=625 YHG=593>war-scarred YHG=592>College. YHG=593>The YHG=593>vice-presidents YHG=594>and YHG=594>the XBD=1409XHG=721 XBD=1547 XBD=1771 XBD=1887 XBD=2026 XBD=2157 XBD=2234 XBD=2358 XBD=2467 XBD=2551 XHG=1369YBD=623 XHG=1420 XHG=1564 XHG=1785 XHG=1899 XHG=2038 XHG=2170 XHG=2247 XHG=2371 XHG=2489 YBD=627YHG=594>2 YBD=628 YBD=638 YBD=632 YBD=629 YBD=636 YBD=630 YHG=596>of YHG=597>whom YHG=598>developed YHG=598>toxic YHG=598>rashes YHG=598>about YHG=598>ninth YHG=598>day; YHG=598>the XBD=161 XBD=409 XBD=744 XBD=954 XBD=1121 XBD=1226 XBD=1305 XBD=660XHG=771 XHG=120 XHG=187 XHG=692 XHG=983 XHG=1149 XHG=1256 XHG=427YBD=678 YBD=667 YBD=668 YBD=676 YBD=668 YBD=676YHG=646>generous YBD=668 YHG=637>19 YHG=637>councillors YHG=637>by YHG=637>donors YHG=637>,(reinforced YHG=636>and YHG=647>an "|>"XBD=2552 XBD=1482 XBD=1844 XBD=1971 XBD=2038 XBD=2161 XBD=2218 XBD=2281 XBD=2331 XBD=2463 XHG=1368 XHG=1505 XHG=1863 XHG=1989 XHG=2054 XHG=2179 XHG=2235 XHG=2297 XHG=2350 XHG=2480 YBD=672 YBD=682 YBD=678 YBD=674 YBD=681 YBD=680 YBD=673 YHG=639>blood YHG=641>sulphaguanidine YHG=642>level, YHG=652>on YHG=643>doses YHG=643>of YHG=643>24 YHG=651>g. YHG=641>daily, YHG=651>was XBD=371 XHG=870 XBD=432 XBD=547 XBD=667 XBD=759 XBD=844 XBD=929 XBD=1062 XBD=1181 XBD=1313 XHG=115 XHG=389 XHG=455 XHG=569 XHG=691 XHG=779 XHG=953YBD=712 XHG=1083 XHG=1206 YBD=721 YBD=720 YBD=721 YBD=713YHG=681>far YBD=712 YHG=680>ex-president YHG=690>or YHG=683>two) YHG=691>were YHG=683>not YHG=683>too YHG=691>away YHG=682>from YHG=680>their " XBD=2552 XBD=1833 XBD=2205 XBD=2292 XHG=1371 XHG=1855 XHG=2216 XHG=2302 YBD=726 YBD=723 YBD=717 YHG=687>10-14mg.perl00c.cm. YHG=686>Jamieson, YHG=687>and YHG=683>Stiven5 have Brodie " XBD=1303 XBD=254 XBD=356 XBD=560 XBD=656 XBD=750 XBD=812 XBD=888 XBD=1046 XBD=1172 XHG=114 XHG=272 XHG=383 XHG=578 XHG=681 XHG=777 XHG=913 XHG=1072 XHG=1197 YBD=764 YBD=762 YBD=765 YBD=755 YHG=726>guests, YHG=724>who YHG=725>included YHG=725>also YHG=725>Mr. YHG=725>S. YHG=726>Bruce, YHG=725>High YHG=724>ComXBD=1446XHG=837 XBD=1591 XBD=1690 XBD=1960 XBD=2150 XBD=2200 XBD=2550 XHG=1368YBD=756 XHG=1460 XHG=1605 XHG=1704 XHG=1973 XHG=2161 XHG=2218 YBD=762YHG=725>M. YBD=760 YBD=761 YBD=769 YHG=731>also YHG=729>shown YHG=730>that YHG=730>considerable YHG=732>amounts YHG=731>of YHG=728>sulphaguanidine " XBD=312 XBD=393 XBD=613 XBD=738 XBD=821 XBD=1012 XBD=1105 XBD=1219 XHG=117 XHG=333 XHG=409 XHG=660 XHG=839 XHG=1028 XHG=1122 XHG=1237 YBD=800 YBD=799 YBD=799 YBD=800 YHG=768>missioner YHG=768>for YHG=769>Australia. YHG=768>But YHG=769>occasion YHG=779>was YHG=778>none YHG=768>the " XBD=1303 XBD=1434XHG=755 XBD=1574 XBD=1633 XBD=1720 XBD=1846 XBD=1907 XBD=2093 XBD=2301 XBD=2551 XHG=1370YBD=799 XHG=1453 XHG=1595 XHG=1654 XHG=1741 XHG=1867 XHG=1925 XHG=2114 XHG=2320 YBD=806YHG=769>the YBD=804 YBD=805 YBD=814 YBD=812 YHG=785>are YHG=774>found YHG=774>in YHG=774>the YHG=775>urine YHG=774>of YHG=773>patients YHG=774>receiving YHG=774>therapeutic XBD=410 XHG=749 XBD=490 XBD=588 XBD=724 XBD=789 XBD=1033 XBD=1153 XBD=1224 XBD=1304 XHG=114 XHG=431 XHG=521 XHG=613 XHG=815YBD=844 XHG=1055 XHG=1181 XHG=1252 YBD=852 YBD=850 YBD=851YHG=813>of YBD=852 YHG=812>less’symbolic, YHG=813>for YHG=813>the YHG=813>Duke YHG=813>Gloucester YHG=813>(who YHG=812>is, YHG=812>by " XBD=2549 XBD=1483 XBD=1548 XBD=1643 XBD=1779 XBD=1879 XBD=2153 XBD=2357 XHG=1374 XHG=1508 XHG=1577 XHG=1672 XHG=1804 XHG=2050 XHG=2174 XHG=2378 YBD=850 YBD=849 YBD=857 YHG=819>doses YHG=818>of YHG=818>the YHG=818>drug, YHG=818>and YHG=817>has YHG=817>observed YHG=816>sulphonWhyte " XBD=1300 XBD=178 XBD=304 XBD=356 XBD=586 XBD=773 XBD=843 XBD=943 XBD=1015 XBD=1110 XHG=111 XHG=206 XHG=334 XHG=385 XHG=617 XHG=804 XHG=975 XHG=1044 XHG=1139 YBD=896 YBD=887 YBD=897 YBD=888 YBD=888 YHG=857>the YHG=866>way, YHG=866>a YHG=857>perpetual YHG=858>student YHG=858>of YHG=857>of YHG=857>the YHG=856>London XBD=1492XHG=872 XBD=1669 XBD=1721 XBD=1800 XBD=1923 XBD=1977 XBD=2039 XBD=2124 XBD=2181 XBD=2243 XBD=2427 XBD=2549 XHG=1366YBD=888 XHG=1509 XHG=1682 XHG=1734 XHG=1817 XHG=1936 XHG=1998 XHG=2056 XHG=2141 XHG=2198 XHG=2260 XHG=2443 YBD=893YHG=867>one YBD=902 YBD=901 YHG=862>amide YHG=862>crystals YHG=862>in YHG=862>the YHG=862>urine YHG=864>18 YHG=864>out YHG=862>of YHG=863>25 YHG=861>patients YHG=862>given XBD=273 XHG=937 XBD=457 XBD=572 XBD=710 XBD=915 XBD=977 XBD=1067 XBD=1298 XHG=114 XHG=296 XHG=473 XHG=598 XHG=727 XHG=1001YBD=931 XHG=1089 YBD=941 YBD=932 YBD=940 YBD=943 YBD=931YHG=902>to YBD=939 YHG=901>medical YHG=901>schools) YHG=902>after YHG=901>being YHG=901>admitted YHG=901>the YHG=900>fellowship " XBD=2549 XBD=1389 XBD=1544 XBD=1693 XBD=1746 XBD=2103 XBD=2300 XBD=2361 XBD=2430 XBD=2495 XHG=1366 XHG=1407 XHG=1564 XHG=1706 XHG=1761 XHG=2123 XHG=2319 XHG=2381 XHG=2454 XHG=2513 YBD=938 YBD=937 YBD=946 YBD=945 YBD=936 YHG=916>a YHG=906>week’s YHG=916>course YHG=906>’sulphaguanidine YHG=906>totalling YHG=907>51 YHG=915>g., YHG=907>14 YHG=906>of " XBD=1302 XBD=247 XBD=305 XBD=433 XBD=542 XBD=639 XBD=675 XBD=833 XBD=1018 XBD=1093 XBD=1168 XHG=112 XHG=265 XHG=324 XHG=449 XHG=559 XHG=652 XHG=850 XHG=1034 XHG=1111 XHG=1187 YBD=984 YBD=976 YBD=975 YBD=983 YBD=975 YBD=984 YHG=945>agreed YHG=946>to YHG=954>carry YHG=945>with YHG=945>him YHG=954>a YHG=944>diploma YHG=944>for YHG=943>Sir YHG=944>Hugh XBD=1472XHG=692 XBD=1636 XBD=1722 XBD=1832 XBD=1894 XBD=1999 XBD=2057 XBD=2176 XBD=2237 XBD=2281 XBD=2394 XBD=2547 XHG=1365YBD=974 XHG=1492 XHG=1656 XHG=1745 XHG=1853 XHG=1915 XHG=2018 XHG=2079 XHG=2198 XHG=2259 XHG=2303 XHG=2423 YBD=990YHG=938>similar YBD=981 YBD=989 YBD=980 YHG=951>them YHG=950>having YHG=950>red YHG=949>cells YHG=959>as YHG=949>well YHG=950>in YHG=950>spite YHG=949>of YHG=959>a YHG=949>fluid YHG=949>intake XBD=271 XHG=811 XBD=360 XBD=417 XBD=499 XBD=695 XBD=789 XBD=833 XBD=1151 XBD=1214 XBD=1301 XHG=113 XHG=290 XHG=377 XHG=433 XHG=514 XHG=713 XHG=855YBD=1018 XHG=1174 XHG=1235 YBD=1027 YBD=1020 YBD=1019 YBD=1027 YBD=1018 YBD=1019 YHG=988>Devine, YHG=998>one YHG=989>of YHG=989>the YHG=988>founders YHG=988>and YHG=997>a YHG=988>past-president YHG=988>of YHG=988>the " XBD=2546 XBD=1405 XBD=1527 XBD=1580 XBD=1767 XBD=1886 XBD=2255 XBD=2419 XBD=2496 XHG=1365 XHG=1435 XHG=1559 XHG=1610 XHG=1798 XHG=1939 XHG=2287 XHG=2448 XHG=2526 YBD=1025 YBD=1034 YBD=1033 YBD=1024 YHG=995>of YHG=1003>over YHG=996>5 YHG=994>pints YHG=993>day. YHG=993>Sulphasuxidine YHG=993>stands YHG=1002>on YHG=1003>a a XBD=236 XHG=776 XBD=520 XBD=691 XBD=753 XBD=973 XBD=1069 XBD=1125 XBD=1301 XHG=115 XHG=259 XHG=545 XHG=713 XHG=993YBD=1072 XHG=1085 XHG=1148 YBD=1064 YBD=1063 YBD=1062 YBD=1063YHG=1032>Surgeons, YBD=1071 YHG=1033>Royal YHG=1032>Australasian YHG=1032>College YHG=1032>of YHG=1032>and YHG=1033>to YHG=1033>present " XBD=2546 XBD=1542 XBD=1693 XBD=1838 XBD=1920 XBD=2040 XBD=2268 XBD=2357 XBD=2466 XHG=1365 XHG=1559 XHG=1719 XHG=1854 XHG=1936 XHG=2056 XHG=2285 XHG=2373 XHG=2484 YBD=1068 YBD=1069 YBD=1077 YBD=1067 YBD=1078 YHG=1038>different YHG=1038>plane YHG=1037>under YHG=1038>the YHG=1047>same YHG=1038>conditions YHG=1037>less YHG=1037>than YHG=1038>2% ; " XBD=141 XBD=199 XBD=296 XBD=351 XBD=586 XBD=645 XBD=709 XBD=839 XBD=930 XBD=1059 XBD=1122 XHG=111 XHG=158 XHG=216 XHG=312 XHG=367 XHG=603 XHG=661 XHG=728 XHG=953 XHG=1082 XHG=1140 YBD=1108 YBD=1107 YBD=1106 YBD=1107 YHG=1077>it YHG=1078>to YHG=1077>him YHG=1077>in YHG=1077>Melbourne YHG=1086>as YHG=1076>he YHG=1076>could YHG=1085>come YHG=1077>to YHG=1076>London " XBD=1301 XBD=1404XHG=862 XBD=1494 XBD=1617 XBD=1809 XBD=1865 XBD=2008 XBD=2071 XBD=2162 XBD=2305 XBD=2406 XBD=2546 XHG=1364YBD=1106 XHG=1428 XHG=1520 XHG=1639 XHG=1834 XHG=1889 XHG=2033 XHG=2096 XHG=2186 XHG=2331 XHG=2431 YBD=1122YHG=1077>not YBD=1121 YBD=1117 YBD=1112 YBD=1113 YHG=1083>of YHG=1083>the YHG=1082>drug YHG=1082>ingested YHG=1082>is YHG=1082>found YHG=1082>in YHG=1082>the YHG=1082>urine, YHG=1081>and YHG=1080>traces " XBD=170 XBD=236 XBD=367 XBD=544 XBD=611 XBD=694 XBD=815 XBD=908 XBD=971 XBD=1134 XBD=1235 XHG=106 XHG=194 XHG=288 XHG=384 XHG=561 XHG=627 XHG=710 XHG=830 XHG=988 XHG=1156 XHG=1260 YBD=1152 YBD=1151 YBD=1150 YBD=1150 YBD=1149 YHG=1121>it. YHG=1120>The YHG=1120>mimosa YHG=1129>on YHG=1120>the YHG=1118>table YHG=1128>was YHG=1119>remind YHG=1119>him YHG=1119>of " XBD=1300 XBD=1454XHG=930 XBD=1515 XBD=1603 XBD=1750 XBD=1848 XBD=2031 XBD=2228 XBD=2344 XBD=2431 XBD=2547 XHG=1363YBD=1150 XHG=1475 XHG=1536 XHG=1625 XHG=1804 XHG=1871 XHG=2051 XHG=2251 XHG=2366 XHG=2451 YBD=1165YHG=1120>to YBD=1157 YBD=1156 YBD=1166 YHG=1126>only YHG=1127>in YHG=1126>the YHG=1126>blood. YHG=1127>In YHG=1126>surgical YHG=1126>practice, YHG=1125>with YHG=1125>the YHG=1124>large XBD=160 XHG=729 XBD=401 XBD=678 XBD=808 XBD=1007 XBD=1224 XBD=1299 XHG=110 XHG=183 XHG=418 XHG=832YBD=1195 XHG=1034 XHG=1249 YBD=1203 YBD=1203YHG=1164>The YBD=1194 YHG=1164>its YHG=1163>Australian YHG=1164>associations. YHG=1164>speeches YHG=1164>(reported YHG=1173>on " XBD=2546 XBD=1532 XBD=1700 XBD=1846 XBD=2017 XBD=2160 XBD=2415 XHG=1362 XHG=1547 XHG=1719 XHG=1868 XHG=2036 XHG=2182 XHG=2436 YBD=1201 YBD=1209 YBD=1210 YBD=1200 YBD=1208 YHG=1170>initial YHG=1170>loading YHG=1170>dose YHG=1169>usually YHG=1171>given, YHG=1169>measurable YHG=1178>quan&dquo; &dquo; " XBD=1298 XBD=271 XBD=404 XBD=488 XBD=584 XBD=699 XBD=814 XBD=910 XBD=992 XBD=1106 XBD=1223 XHG=111 XHG=295 XHG=423 XHG=514 XHG=609 XHG=725 XHG=839 XHG=1017 XHG=1122 XHG=1249 YBD=1240 YBD=1239 YBD=1248 YBD=1239 YBD=1238 YHG=1208>another YHG=1211>page) YHG=1208>did YHG=1210>not YHG=1208>take YHG=1208>long YHG=1208>but YHG=1207>chat YHG=1210>went YHG=1217>on XBD=1468XHG=927 XBD=1558 XBD=1800 XBD=1944 XBD=2009 XBD=2101 XBD=2253 XBD=2461 XBD=2547 XHG=1363YBD=1238 XHG=1494 XHG=1584 XHG=1825 XHG=1971 XHG=2035 XHG=2128 XHG=2281 XHG=2486 YBD=1244YHG=1208>the YBD=1249 YBD=1254 YBD=1245 YHG=1214>tities YHG=1223>are YHG=1214>sometimes YHG=1214>found YHG=1214>in YHG=1213>blood, YHG=1212>although YHG=1214>the XBD=354 XHG=768 XBD=480 XBD=579 XBD=737 XBD=952 XBD=1110 XBD=1296 XHG=108 XHG=381 XHG=512 XHG=614 XHG=983YBD=1288 XHG=1135 YBD=1283 YBD=1284 YBD=1292 YBD=1283 YBD=1292YHG=1252>brothers, YHG=1252>contentedly YHG=1252>until YHG=1253>the YHG=1252>Royal YHG=1252>before YHG=1252>leaving, " XBD=2547 XBD=1461 XBD=1511 XBD=1675 XBD=1788 XBD=1922 XBD=2055 XBD=2170 XBD=2278 XBD=2339 XBD=2424 XHG=1362 XHG=1480 XHG=1533 XHG=1696 XHG=1810 XHG=1942 XHG=2075 XHG=2192 XHG=2300 XHG=2359 XHG=2444 YBD=1298 YBD=1299 YBD=1290 YBD=1289 YHG=1258>level YHG=1259>is YHG=1258>always YHG=1268>very YHG=1258>much YHG=1258>lower YHG=1258>than YHG=1258>that YHG=1258>of YHG=1257>the YHG=1258>other " XBD=204 XBD=382 XBD=457 XBD=552 XBD=680 XBD=875 XBD=950 XBD=1048 XHG=108 XHG=236 XHG=416 XHG=491 XHG=576 XHG=712 XHG=982 XHG=1084 YBD=1328 YBD=1328 YHG=1306>were YHG=1297>invited YHG=1305>to YHG=1306>see YHG=1297>what YHG=1298>remains YHG=1296>the YHG=1296>Hunterian " XBD=1298 XBD=1610XHG=910 XHG=1362YBD=1328 YBD=1343YHG=1297>of YHG=1303>compounds. " XBD=1295 XBD=282 XBD=385 XBD=480 XBD=618 XBD=705 XBD=783 XBD=1049 XHG=104 XHG=310 XHG=413 XHG=507 XHG=645 XHG=732 XHG=809 XHG=1111 YBD=1381 YBD=1372 YBD=1372 YBD=1381 YHG=1350>museum YHG=1341>and YHG=1342>the YHG=1342>plans YHG=1342>for YHG=1342>its YHG=1341>restoration. XBD=1449 XHG=2440 XBD=1503 XBD=1594 XBD=1681 XBD=1866 XBD=1928 XBD=2080 XBD=2152 XBD=2239 XBD=2418 XBD=2545 XHG=1413 YBD=1378 XHG=1472 XHG=1525 XHG=1616 XHG=1704 XHG=1888 XHG=1952 XHG=2103 XHG=2174 XHG=2262 YBD=1386 YHG=1341>Surgeons YBD=1377 YHG=1347>It YHG=1347>is YHG=1349>not YHG=1348>yet YHG=1347>possible YHG=1348>to YHG=1347>decide YHG=1357>on YHG=1347>the YHG=1346>relative YHG=1347>value XBD=174 XHG=871 XBD=314 XBD=429 XBD=550 XBD=660 XBD=730 XBD=848 XBD=930 XBD=1139 XBD=1297 XHG=108 XHG=197 XHG=338 XHG=451 XHG=574 XHG=682 XHG=755 XHG=953YBD=1416 XHG=1162 YBD=1425 YBD=1424YHG=1385>for YHG=1385>the YHG=1385>world YHG=1395>over YHG=1386>have YHG=1395>now YHG=1395>no YHG=1386>time YHG=1385>anything YHG=1387>except " XBD=2547 XBD=1401 XBD=1506 XBD=1698 XBD=2044 XBD=2123 XBD=2227 XBD=2473 XHG=1361 XHG=1440 XHG=1546 XHG=1737 XHG=2083 XHG=2162 XHG=2267 XHG=2510 YBD=1431 YBD=1421 YBD=1422 YHG=1391>of YHG=1391>various YHG=1390>sulphonamides YHG=1391>in YHG=1391>the YHG=1392>treatment YHG=1392>of has XBD=205 XHG=720 XBD=315 XBD=420 XBD=474 XBD=624 XBD=703 XBD=796 XBD=1007 XBD=1126 XBD=1214 XBD=1297 XHG=106 XHG=221 XHG=331 XHG=435 XHG=490 XHG=640 XHG=813YBD=1461 XHG=1023 XHG=1145 XHG=1231 YBD=1470 YBD=1460 YBD=1469 YBD=1470 YBD=1460YHG=1430>and YHG=1429>their YHG=1429>grim YHG=1429>task YHG=1430>of YHG=1430>saving YHG=1429>life YHG=1429>salvaging YHG=1430>limb, YHG=1429>but YHG=1430>the XBD=1559 XBD=1800 XBD=1905 XBD=2113 XHG=1361 XHG=1589 XHG=1829 XHG=1930 YBD=1467 YBD=1472 YHG=1435>intestinal YHG=1435>infections, YHG=1435>and YHG=1435>Paulley " XBD=2544 XBD=2435 XHG=2238 XHG=2463 YBD=1475 YBD=1466 YHG=1434>suggested YHG=1435>that " XBD=1297 XBD=321 XBD=531 XBD=679 XBD=773 XBD=893 XBD=983 XBD=1231 XHG=109 XHG=347 XHG=555 XHG=703 XHG=798 XHG=917 XHG=1008 XHG=1257 YBD=1506 YBD=1505 YBD=1514 YBD=1505 YHG=1474>Hunterian YHG=1474>tradition YHG=1474>which YHG=1474>has YHG=1474>been YHG=1474>the YHG=1473>inspiration YHG=1473>of XBD=1672 XHG=2414 XBD=1771 XBD=2035 XBD=2156 XBD=2251 XBD=2384 XBD=2544 XHG=1360 YBD=1520 XHG=1702 XHG=1801 XHG=2065 XHG=2185 XHG=2283 YBD=1511 YHG=1479>widely YBD=1510 YHG=1480>sulphapyridine YHG=1480>has YHG=1479>advantages YHG=1489>over YHG=1479>the YHG=1489>more XBD=205 XHG=808 XBD=436 XBD=547 XBD=614 XBD=708 XBD=791 XBD=980 XBD=1073 XBD=1114 XBD=1296 XHG=104 XHG=220 XHG=453 XHG=564 XHG=632 XHG=725 XHG=997YBD=1549 XHG=1092 XHG=1131 YBD=1549 YBD=1549YHG=1518>occasion YBD=1558 YHG=1517>their YHG=1518>handicraft YHG=1518>lives YHG=1528>on YHG=1518>and YHG=1518>the YHG=1528>was YHG=1528>a YHG=1518>recogni" XBD=2542 XBD=1453 XBD=1824 XBD=1914 XBD=1964 XBD=2082 XBD=2274 XBD=2378 XHG=1360 XHG=1473 XHG=1878 XHG=1933 XHG=1985 XHG=2099 XHG=2293 XHG=2398 YBD=1564 YBD=1555 YBD=1554 YBD=1563 YHG=1525>used YHG=1524>sulphaguanidine. YHG=1524>It YHG=1524>is YHG=1523>clear YHG=1524>however YHG=1524>that YHG=1523>sulpha" XBD=661 XBD=187 XBD=247 XBD=353 XBD=548 XHG=104 XHG=208 XHG=266 XHG=374 YBD=1601 YHG=1562>tion YHG=1562>of YHG=1562>that YHG=1570>supreme XBD=1565XHG=568 XBD=1619 XBD=1666 XBD=1833 XBD=2043 XBD=2173 XBD=2275 XBD=2370 XBD=2542 XHG=1360YBD=1593 XHG=1589 XHG=1643 XHG=1689 XHG=1856 XHG=2066 XHG=2199 XHG=2299 XHG=2393 YBD=1608YHG=1562>fact. YBD=1599 YBD=1598 YBD=1607 YHG=1568>guanidine YHG=1569>is YHG=1577>a YHG=1568>readily YHG=1568>absorbed YHG=1568>drug, YHG=1567>and YHG=1577>one YHG=1568>capable " XBD=2542 XBD=1400 XHG=2361 XBD=1558 XBD=1656 XBD=1724 XBD=1857 XBD=2110 XBD=2216 XBD=2331 XHG=1360 XHG=1428 XHG=1584 XHG=1684 XHG=1754 XHG=1887 XHG=2141 XHG=2244 YBD=1653 YBD=1643 YHG=1612>of YHG=1612>giving YHG=1613>rise YHG=1614>to YHG=1612>toxic YHG=1613>symptoms, YHG=1612>and YHG=1612>that YHG=1612>adequate TOXICITYYBD=1652 OF SULPHAGUANIDINE " XBD=2553 XBD=1516 XHG=2453 XBD=1675 XBD=1796 XBD=1862 XBD=2115 XBD=2173 XBD=2353 XBD=2436 XHG=1360 YBD=1696 XHG=1535 XHG=1694 XHG=1816 XHG=1881 XHG=2134 XHG=2192 XHG=2371 YBD=1687 YHG=1656>drug* YBD=1688 YHG=1656>urinary YHG=1658>output YHG=1659>must YHG=1656>be YHG=1656>maintained YHG=1658>to YHG=1658>prevent YHG=1656>the "" XBD=1307 XBD=543 XBD=656 XBD=793 XBD=971 XBD=1105 XBD=1186 XHG=156 XHG=586 XHG=698 XHG=833 XHG=1013 XHG=1147 XHG=1228 YBD=1715 YBD=1716 YBD=1724 YBD=1715 YBD=1716 YHG=1684>SULPHAGUANIDINE YHG=1685>has YHG=1685>been YHG=1685>widely YHG=1685>used YHG=1684>in YHG=1684>the XBD=1614 XBD=1710 XBD=1852 XBD=1901 XBD=1958 XBD=2180 XBD=2431 XBD=2543 XHG=1360 XHG=1631 XHG=1763 XHG=1869 XHG=1919 XHG=1977 XHG=2197 XHG=2448 YBD=1731 YBD=1740 YBD=1732 YHG=1701>crystallising YHG=1703>out. YHG=1700>This YHG=1700>is YHG=1701>of YHG=1701>particular YHG=1701>importance YHG=1701>since " XBD=317 XBD=385 XBD=593 XBD=817 XBD=1000 XBD=1106 XBD=1203 XBD=1298 XHG=109 XHG=346 XHG=413 XHG=621 XHG=845 XHG=1031 XHG=1134 XHG=1232 YBD=1760 YBD=1759 YBD=1765 YBD=1760 YBD=1759 YHG=1730>treatment YHG=1729>of YHG=1729>infective YHG=1728>intestinal YHG=1729>disease, YHG=1729>and YHG=1729>has " XBD=2542 XBD=1425 XHG=2388 XBD=1668 XBD=1755 XBD=1905 XBD=1999 XBD=2124 XBD=2182 XBD=2362 XHG=1358 YBD=1784 XHG=1453 XHG=1696 XHG=1782 XHG=1933 XHG=2028 XHG=2151 XHG=2211 YBD=1776 YHG=1729>the YBD=1785 YBD=1775 YHG=1745>conditions YHG=1745>for YHG=1744>which YHG=1744>the YHG=1745>drug YHG=1744>is YHG=1745>usually YHG=1744>given"" XBD=1296 XBD=326 XBD=397 XBD=541 XBD=662 XBD=786 XBD=972 XBD=1188 XHG=108 XHG=359 XHG=428 XHG=572 XHG=693 XHG=817 XHG=1003 XHG=1220 YBD=1803 YBD=1812 YBD=1813 YBD=1804 YHG=1772>reputation YHG=1773>of YHG=1773>being YHG=1772>only YHG=1782>very YHG=1772>slightly YHG=1772>absorbed XBD=1565 XHG=2438 XBD=1662 XBD=1981 XBD=2310 XBD=2373 XBD=2418 XBD=2543 XHG=1357 YBD=1820 XHG=1587 XHG=1684 XHG=2002 XHG=2332 XHG=2396 YBD=1829 YHG=1773>and YBD=1819 YHG=1789>dysentery YHG=1788>and YHG=1789>dysentery-like YHG=1789>illnesses-tend YHG=1791>to YHG=1798>a YHG=1789>small "" XBD=1296 XBD=329 XBD=565 XBD=664 XBD=816 XBD=918 XBD=973 XBD=1030 XBD=1167 XHG=108 XHG=355 XHG=618 XHG=688 XHG=839 XHG=942 XHG=998 XHG=1056 XHG=1193 YBD=1856 YBD=1848 YBD=1847 YBD=1848 YBD=1848 YHG=1816>practically YHG=1817>non-toxic. YHG=1817>In YHG=1816>actual YHG=1817>fact YHG=1817>it YHG=1817>is YHG=1817>much XBD=1500 XHG=2360 XBD=1564 XBD=1853 XBD=1982 XBD=2129 XBD=2337 XBD=2542 XHG=1359 YBD=1869 XHG=1523 XHG=1586 XHG=1876 XHG=2004 XHG=2151 YBD=1872 YHG=1826>more YBD=1865 YBD=1864 YBD=1873 YHG=1835>output YHG=1833>of YHG=1833>concentrated YHG=1833>urine YHG=1833>unless YHG=1833>energetic YHG=1842>measures "" XBD=1294 XBD=224 XBD=424 XBD=514 XBD=634 XBD=758 XBD=860 XBD=907 XBD=1110 XHG=106 XHG=238 XHG=439 XHG=530 XHG=648 XHG=766 XHG=921 XHG=1124 YBD=1901 YBD=1903 YBD=1901 YBD=1892 YHG=1861>freely YHG=1861>absorbed YHG=1861>and YHG=1870>more YHG=1861>toxic YHG=1861>than YHG=1861>generally YHG=1861>realised. XBD=1421XHG=876 XBD=1579 XBD=1978 XBD=2036 XBD=2103 XBD=2178 XBD=2367 XBD=2467 XBD=2540 XHG=1358YBD=1892 XHG=1448 XHG=1632 XHG=2005 XHG=2063 XHG=2132 XHG=2205 XHG=2394 XHG=2494 YBD=1917YHG=1861>is YBD=1914 YBD=1909 YBD=1908 YHG=1886>are YHG=1877>taken. YHG=1877>Sulphaguanidine YHG=1877>is YHG=1880>to YHG=1877>be YHG=1877>treated, YHG=1877>like YHG=1877>all "" XBD=1292 XBD=145 XBD=237 XBD=334 XBD=546 XBD=601 XBD=712 XBD=781 XBD=929 XBD=1020 XBD=1193 XHG=108 XHG=160 XHG=253 XHG=351 XHG=562 XHG=622 XHG=728 XHG=797 XHG=945 XHG=1038 XHG=1207 YBD=1935 YBD=1946 YBD=1936 YBD=1936 YBD=1942 YBD=1937 YHG=1905>It YHG=1914>was YHG=1905>first YHG=1905>described YHG=1906>in YHG=1906>1938 YHG=1901>by YHG=1906>Buttle YHG=1905>and YHG=1906>others,l XBD=1468 XHG=2321 XBD=1825 XBD=1905 XBD=1965 XBD=2177 XBD=2285 XBD=2542 XHG=1358 YBD=1962 XHG=1505 XHG=1864 XHG=1941 XHG=2001 XHG=2215 YBD=1961 YHG=1905>who YBD=1952 YBD=1953 YHG=1921>other YHG=1921>sulphonamides, YHG=1931>as YHG=1931>a YHG=1922>valuable YHG=1922>but YHG=1921>potentially "" XBD=1294 XBD=288 XBD=336 XBD=397 XBD=441 XBD=570 XBD=638 XBD=962 XBD=1019 XBD=1200 XHG=106 XHG=306 XHG=357 XHG=420 XHG=457 XHG=587 XHG=648 XHG=980 XHG=1038 XHG=1218 YBD=1962 YBD=1980 YBD=1989 YBD=1981 YBD=1990 YBD=1981 YHG=1949>regarded YHG=1949>it YHG=1958>as YHG=1950>&dquo; YHG=1950>equal YHG=1943>to YHG=1949>sulphanilamide YHG=1950>in YHG=1950>activity XBD=1570 XHG=2387 XBD=1693 XBD=1792 XBD=1946 XBD=2034 XBD=2100 XBD=2314 XBD=2370 XBD=2541 XHG=1356 YBD=1997 XHG=1589 XHG=1716 XHG=1811 XHG=1966 XHG=2054 XHG=2121 XHG=2332 YBD=2006 YHG=1950>and YBD=1996 YHG=1966>dangerous YHG=1966>drug, YHG=1966>and YHG=1966>should YHG=1968>not YHG=1966>be YHG=1966>exhibited YHG=1966>in YHG=1965>reckless "" XBD=1293 XBD=305 XBD=395 XBD=473 XBD=630 XBD=682 XBD=873 XBD=959 XBD=1030 XHG=105 XHG=320 XHG=408 XHG=487 XHG=643 XHG=694 XHG=971 XHG=1041 XHG=1280 YBD=2033 YBD=2024 YBD=2025 YBD=2026 YBD=2013 YHG=1993>toxicity,&dquo; YHG=1993>and YHG=1994>the YHG=1994>studies YHG=1993>of YHG=1994>Marshall YHG=1994>his YHG=1994>co-workers YHG=1994>2 XBD=1506XHG=884 XBD=1563 XBD=1611 XBD=1693 XBD=1818 XBD=1875 XBD=1997 XBD=2184 XBD=2334 XBD=2537 XHG=1355YBD=2025 XHG=1522 XHG=1581 XHG=1628 XHG=1709 XHG=1835 XHG=1894 XHG=2015 XHG=2203 XHG=2387 YBD=2040YHG=1994>and YBD=2041 YBD=2049 YBD=2050 YHG=2010>dosage, YHG=2019>as YHG=2010>is YHG=2010>the YHG=2010>habit YHG=2010>in YHG=2019>some YHG=2012>quarters YHG=2010>today. YHG=2010>Sulpha"" XBD=1292 XBD=144 XBD=274 XBD=395 XBD=542 XBD=658 XBD=731 XBD=972 XBD=1116 XHG=104 XHG=172 XHG=297 XHG=418 XHG=565 XHG=681 XHG=754 XHG=996 XHG=1141 YBD=2070 YBD=2074 YBD=2069 YBD=2078 YBD=2075 YBD=2070 YHG=2038>in YHG=2039>1940, YHG=2037>from YHG=2038>which YHG=2037>time YHG=2038>its YHG=2038>popularity YHG=2039>dates, XBD=1529 XHG=2503 XBD=1628 XBD=1818 XBD=1949 XBD=2083 XBD=2146 XBD=2232 XBD=2358 XBD=2482 XBD=2539 XHG=1355 YBD=2084 XHG=1552 XHG=1649 XHG=1840 XHG=1971 XHG=2106 XHG=2166 XHG=2254 XHG=2379 YBD=2085 YHG=2039>showed YBD=2094 YHG=2054>suxidine YHG=2054>and YHG=2054>possibly YHG=2054>other YHG=2054>drugs YHG=2055>of YHG=2054>the YHG=2064>same YHG=2056>type, YHG=2054>in "" XBD=1293 XBD=195 XBD=287 XBD=477 XBD=555 XBD=718 XBD=775 XBD=985 XBD=1059 XBD=1190 XHG=108 XHG=221 XHG=313 XHG=503 XHG=583 XHG=744 XHG=1011 XHG=1088 XHG=1217 YBD=2122 YBD=2113 YBD=2114 YHG=2082>that YHG=2082>the YHG=2082>toxicity YHG=2082>by YHG=2082>mouth YHG=2082>is YHG=2093>no YHG=2092>more YHG=2083>and XBD=1477XHG=802 XBD=1544 XBD=1898 XBD=2033 XBD=2081 XBD=2279 XBD=2337 XBD=2429 XBD=2540 XHG=1353YBD=2123 XHG=1494 XHG=1562 XHG=1914 XHG=2051 XHG=2099 XHG=2297 XHG=2364 XHG=2454 YBD=2138YHG=2083>certainly YBD=2129 YBD=2130 YBD=2136 YHG=2098>which YHG=2107>an YHG=2098>acyl-substituent YHG=2107>group YHG=2099>is YHG=2099>attached YHG=2100>to YHG=2099>the YHG=2098>NH2 "" XBD=1293 XBD=294 XBD=382 XBD=494 XBD=600 XBD=658 XBD=983 XBD=1042 XHG=106 XHG=309 XHG=399 XHG=512 XHG=618 XHG=1000 XHG=1060 YBD=2158 YBD=2157 YBD=2158 YBD=2167 YHG=2126>probably YHG=2126>less YHG=2127>than YHG=2126>that YHG=2127>of YHG=2137>or YHG=2126>sulphathiaXBD=1472XHG=675 XBD=1550 XBD=1895 XBD=2031 XBD=2106 XBD=2189 XBD=2300 XBD=2432 XBD=2538 XHG=1353YBD=2166 XHG=1509 XHG=1584 XHG=1931 XHG=2066 XHG=2143 XHG=2223 XHG=2334 XHG=2465 YBD=2182YHG=2126>sulphapyridine YBD=2173 YHG=2152>group YHG=2142>of YHG=2142>sulphathiazole, YHG=2151>seem YHG=2144>to YHG=2143>be YHG=2143>free YHG=2143>from YHG=2142>this "" XBD=1293 XBD=198 XBD=287 XBD=391 XBD=596 XBD=677 XBD=810 XBD=880 XBD=1021 XBD=1120 XHG=106 XHG=249 XHG=314 XHG=419 XHG=624 XHG=705 XHG=838 XHG=909 XHG=1048 XHG=1148 YBD=2210 YBD=2202 YBD=2202 YBD=2202 YBD=2211 YHG=2171>zole. YHG=2171>It YHG=2181>was YHG=2171>reported YHG=2171>by YHG=2170>them YHG=2181>as YHG=2171>much YHG=2171>less XBD=1507 XHG=2451 XBD=1606 XBD=1664 XBD=1759 XBD=1828 XBD=1889 XBD=2008 XBD=2245 XBD=2304 XBD=2434 XBD=2539 XHG=1354 YBD=2226 XHG=1529 XHG=1625 XHG=1684 XHG=1778 XHG=1849 XHG=1910 XHG=2026 XHG=2264 XHG=2322 YBD=2217 YHG=2171>readily YBD=2227 YHG=2187>danger, YHG=2187>and YHG=2186>live YHG=2196>up YHG=2188>to YHG=2186>their YHG=2187>reputation YHG=2187>of YHG=2186>being YHG=2196>very "" XBD=1291 XBD=292 XBD=411 XBD=540 XBD=897 XBD=1007 XBD=1121 XBD=1190 XBD=1232 XHG=106 XHG=316 XHG=431 XHG=565 XHG=936 XHG=1032 XHG=1145 XHG=1211 XHG=1255 YBD=2246 YBD=2254 YBD=2246 YBD=2251 YBD=2246 YBD=2255 YHG=2215>absorbed YHG=2215>than YHG=2215>other YHG=2214>sulphonamides YHG=2225>one YHG=2216>dose YHG=2216>of YHG=2217>6 ; XBD=1487 XHG=1504 XBD=1719 XHG=1352 YBD=2262 YBD=2270 YHG=2225>g. YHG=2230>poorly YHG=2230>absorbed.a " XBD=1292 XBD=172 XHG=869 XBD=256 XBD=542 XBD=662 XBD=709 XBD=845 XBD=982 XHG=105 XHG=196 XHG=283 XHG=566 XHG=687 XHG=732 XHG=1007YBD=2290 YBD=2300 YBD=2299 YBD=2291YHG=2259>blood YHG=2269>per YHG=2259>kg. YHG=2259>body-weight YHG=2268>gave YHG=2268>a YHG=2258>lower YHG=2260>concentration YANDELL HENDERSON "|>"XBD=1290 XBD=145 XBD=229 XBD=344 XBD=457 XBD=593 XBD=680 XBD=761 XBD=827 XBD=1160 XBD=537XHG=782 XHG=96 XHG=163 XHG=248 XHG=363 XHG=557 XHG=613 XHG=700 XHG=840 XHG=1212 XHG=479 YBD=2335 YBD=2335 YBD=2344 YBD=2343 YBD=2334 YBD=2343 YBD=2335 YBD=2334 YHG=2304>of YHG=2304>the YHG=2304>drug YHG=2304>than YHG=2313>g. YHG=2312>per YHG=2303>kg. YHG=2304>of. YHG=2303>sulphapyridine. YHG=2305>0-5 YHG=2304>But " XBD=2539 XBD=264 XBD=330 XBD=696 XBD=950 XBD=1040 XBD=1185 XBD=1290 XHG=105 XHG=291 XHG=356 XHG=723 XHG=977 XHG=1065 XHG=1212 YBD=2388 YBD=2379 YBD=2387 YBD=2378 YBD=2378 YBD=2378 YHG=2348>crystals YHG=2349>of YHG=2346>sulphaguanidine YHG=2347>derivatives YHG=2357>are YHG=2348>found YHG=2357>sur|>" " XBD=1599 XBD=2029 XBD=2087 XBD=2211 XBD=2355 XBD=2487 XBD=1778 XHG=1405 XHG=1797 XHG=2049 XHG=2106 XHG=2229 XHG=2373 XHG=2502 XHG=1618 YBD=2390 YBD=2396 YBD=2391 YBD=2389 YBD=2390 YHG=2359>Professor YHG=2360>Henderson, YHG=2360>of YHG=2360>Yale, YHG=2360>whose YHG=2359>death YHG=2359>in YHG=2359>Yandell "" XBD=1293 XBD=287 XBD=408 XBD=465 XBD=550 XBD=743 XBD=858 XBD=915 XBD=998 XBD=1128 XHG=104 XHG=304 XHG=427 XHG=483 XHG=567 XHG=760 XHG=877 XHG=1016 XHG=1146 YBD=2432 YBD=2423 YBD=2427 YBD=2430 YBD=2422 YBD=2422 YBD=2431 YHG=2392>prisingly YHG=2393>often YHG=2392>in YHG=2392>the YHG=2391>urine, YHG=2391>spite YHG=2392>of YHG=2392>much YHG=2393>greater in XBD=1561XHG=932 XBD=1665 XBD=1916 XBD=2016 XBD=2191 XBD=2311 XBD=2385 XBD=2539 XHG=1357YBD=2421 XHG=1588 XHG=1692 XHG=1941 XHG=2045 XHG=2221 XHG=2338 XHG=2413 YBD=2433YHG=2391>the YBD=2439 YBD=2443 YBD=2434 YBD=2441 YHG=2402>California YHG=2412>was YHG=2403>announced YHG=2403>last YHG=2404>month, YHG=2413>may YHG=2403>be YHG=2402>briefly "" XBD=1296 XBD=300 XBD=364 XBD=438 XBD=590 XBD=823 XBD=943 XBD=1054 XBD=1119 XHG=105 XHG=323 XHG=388 XHG=464 XHG=614 XHG=848 XHG=968 XHG=1080 XHG=1144 YBD=2476 YBD=2467 YBD=2474 YBD=2466 YBD=2465 YBD=2465 YBD=2465 YBD=2474 YHG=2436>solubility YHG=2436>of YHG=2436>its YHG=2434>acetyl YHG=2434>derivative YHG=2435>than YHG=2434>that YHG=2435>of YHG=2435>sulphaXBD=1553 XHG=2476 XBD=1620 XBD=1711 XBD=1826 XBD=1936 XBD=2033 XBD=2200 XBD=2378 XBD=2451 XBD=2538 XHG=1357 YBD=2477 XHG=1579 XHG=1645 XHG=1738 XHG=1852 XHG=1961 XHG=2059 XHG=2226 XHG=2403 YBD=2476 YHG=2446>the YBD=2486 YBD=2478 YHG=2446>described YHG=2456>as YHG=2447>the YHG=2456>man YHG=2446>who YHG=2449>put YHG=2447>carbon YHG=2447>dioxide YHG=2456>on XBD=278 XHG=886 XBD=341 XBD=674 XBD=865 XBD=972 XBD=1016 XBD=1294 XHG=105 XHG=300 XHG=362 XHG=698 XHG=994YBD=2509 XHG=1038 YBD=2519 YBD=2511 YBD=2520 YBD=2518 YBD=2509 YBD=2511YHG=2479>that YHG=2480>pyridine YHG=2490>or YHG=2479>sulphathiazole, YHG=2478>showing YHG=2488>a YHG=2479>considerable "" XBD=2537 XBD=1444 XBD=1502 XBD=1542 XBD=1795 XBD=1935 XBD=2025 XBD=2118 XBD=2288 XBD=2439 XHG=1355 XHG=1461 XHG=1519 XHG=1558 XHG=1811 XHG=1988 XHG=2040 XHG=2134 XHG=2303 XHG=2455 YBD=2520 YBD=2529 YBD=2530 YBD=2522 YBD=2521 YHG=2500>map YHG=2500>as YHG=2499>a YHG=2490>therapeutic YHG=2492>agent. YHG=2490>It YHG=2500>was YHG=2490>already YHG=2491>known YHG=2490>that "" XBD=1294 XBD=326 XBD=374 XBD=591 XBD=753 XBD=862 XBD=983 XBD=1213 XHG=104 XHG=343 XHG=392 XHG=644 XHG=770 XHG=1001 XHG=1231 YBD=2563 YBD=2556 YBD=2554 YBD=2562 YBD=2553 YHG=2524>proportion YHG=2524>is YHG=2523>absorbed. YHG=2523>Cases YHG=2523>with YHG=2524>symptoms YHG=2532>are XBD=1496XHG=881 XBD=1669 XBD=1722 XBD=1766 XBD=1934 XBD=2129 XBD=2191 XBD=2448 XBD=2537 XHG=1354YBD=2553 XHG=1518 XHG=1690 XHG=1744 XHG=1787 XHG=1954 XHG=2150 XHG=2213 XHG=2471 YBD=2574YHG=2522>toxic YBD=2565 YHG=2527>carbon YHG=2534>dioxide YHG=2534>is YHG=2544>a YHG=2534>normal YHG=2534>stimulus YHG=2536>to YHG=2535>respiration, YHG=2534>but "" XBD=1293 XBD=259 XBD=331 XBD=625 XBD=750 XBD=961 XBD=1007 XBD=1177 XHG=106 XHG=283 XHG=353 XHG=650 XHG=774 XHG=984 XHG=1029 XHG=1199 YBD=2607 YBD=2599 YBD=2598 YBD=2597 YBD=2606 YBD=2598 YHG=2568>already YHG=2578>on YHG=2568>record-thus YHG=2567>Cole3 YHG=2566>mentions YHG=2576>a YHG=2567>patient XBD=1396 XHG=2223 XBD=1636 XBD=1705 XBD=1798 XBD=1878 XBD=2107 XBD=2208 XBD=2535 XHG=1354 YBD=2617 XHG=1414 XHG=1649 XHG=1720 XHG=1813 XHG=1892 XHG=2121 YBD=2618 YHG=2566>with YBD=2609 YHG=2580>to YHG=2578>Henderson YHG=2587>we YHG=2588>owe YHG=2578>the YHG=2578>suggestion YHG=2579>that YHG=2578>over-breathing, "" XBD=1292 XBD=310 XBD=450 XBD=551 XBD=778 XBD=818 XBD=1095 XBD=1200 XHG=105 XHG=328 XHG=466 XHG=569 XHG=835 XHG=1112 XHG=1217 YBD=2643 YBD=2651 YBD=2642 YBD=2641 YHG=2611>ulcerative YHG=2612>colitis YHG=2612>who YHG=2611>developed YHG=2610>morbilliform YHG=2611>rash YHG=2611>and XBD=1447XHG=795 XBD=1510 XBD=1622 XBD=1689 XBD=1847 XBD=1921 XBD=2101 XBD=2318 XBD=2381 XBD=2535 XHG=1354YBD=2641 XHG=1468 XHG=1532 XHG=1643 XHG=1711 XHG=1869 XHG=1941 XHG=2122 XHG=2339 XHG=2400 YBD=2661YHG=2621>a YBD=2653 YBD=2662 YHG=2623>such YHG=2631>as YHG=2632>may YHG=2622>be YHG=2622>caused YHG=2621>by YHG=2622>surgical YHG=2623>operation YHG=2631>or YHG=2622>injury, " XBD=1291 XBD=292 XBD=388 XBD=456 XBD=549 XBD=683 XBD=781 XBD=884 XBD=1007 XBD=1188 XHG=105 XHG=317 XHG=416 XHG=483 XHG=576 XHG=736 XHG=807 XHG=909 XHG=1034 XHG=1215 YBD=2695 YBD=2687 YBD=2696 YBD=2686 YBD=2685 YBD=2685 YHG=2655>vomiting YHG=2656>due YHG=2658>to YHG=2657>the YHG=2656>drug. YHG=2656>In YHG=2655>this YHG=2655>issue YHG=2654>Crofton XBD=1445 XHG=2472 XBD=1554 XBD=1618 XBD=1775 XBD=1837 XBD=1925 XBD=2168 XBD=2268 XBD=2420 XBD=2536 XHG=1355 YBD=2695 XHG=1467 XHG=1577 XHG=1641 XHG=1799 XHG=1860 XHG=1948 XHG=2192 XHG=2293 YBD=2705 YHG=2655>and YBD=2697 YBD=2696 YHG=2676>may YHG=2666>lead YHG=2668>to YHG=2666>failure YHG=2666>of YHG=2666>the YHG=2666>circulation YHG=2666>and YHG=2665>death. YHG=2665>His XBD=237 XHG=756 XBD=439 XBD=581 XBD=720 XBD=796 XBD=1064 XBD=1293 XHG=104 XHG=272 XHG=474 XHG=618 XHG=831YBD=2730 XHG=1098 YBD=2739 YBD=2731 YBD=2730 YBD=2738YHG=2699>of YHG=2699>Diggle YHG=2699>describe YHG=2700>three YHG=2709>cases YHG=2698>confusional YHG=2698>psychosis " XBD=2533 XBD=1435 XBD=1580 XBD=1656 XBD=1758 XBD=1888 XBD=1990 XBD=2214 XBD=2280 XBD=2372 XHG=1352 XHG=1460 XHG=1601 XHG=1681 XHG=1783 XHG=1912 XHG=2014 XHG=2240 XHG=2306 XHG=2396 YBD=2741 YBD=2743 YBD=2748 YBD=2749 YBD=2740 YHG=2709>first YHG=2718>paper YHG=2719>on YHG=2710>this YHG=2710>topic YHG=2719>was YHG=2709>published YHG=2710>in YHG=2709>the YHG=2708>British XBD=243 XBD=365 XBD=733 XBD=968 XBD=1034 XBD=1290 XHG=104 XHG=268 XHG=394 XHG=760 XHG=995 XHG=1060 YBD=2782 YBD=2773 YBD=2783 YBD=2774 YBD=2772 YBD=2781 YHG=2743>arising YHG=2743>from YHG=2743>sulphaguanidine YHG=2744>treatment YHG=2742>of YHG=2743>dysentery ; |>|>" " |>" XBD=1689 XBD=1738 XBD=1856 XBD=1997 XBD=2085 XBD=2223 XBD=2357 XBD=2537 XBD=1517 XHG=1528 XHG=1699 XHG=1755 XHG=1908 XHG=2009 XHG=2097 XHG=2235 XHG=2368 XHG=1355 YBD=2783 YBD=2784 YBD=2783 YBD=2784 YHG=2753>J YHG=2753>in YHG=2754>1906. YHG=2753>This YHG=2753>and YHG=2753>others YHG=2753>which YHG=2749>followed YHG=2753>.4ledival oumal "" XBD=1292 XBD=204 XBD=331 XBD=444 XBD=548 XBD=785 XBD=996 XBD=1126 XHG=103 XHG=228 XHG=359 XHG=471 XHG=577 XHG=813 XHG=1048 XHG=1154 YBD=2816 YBD=2817 YBD=2826 YBD=2816 YBD=2825 YHG=2786>their YHG=2785>third YHG=2795>case YHG=2787>also YHG=2787>developed YHG=2786>cyanosis. YHG=2785>The YHG=2785>dosage XBD=1501 XHG=2306 XBD=1699 XBD=1791 XBD=1918 XBD=2162 XBD=2276 XBD=2535 XHG=1353 YBD=2830 XHG=1528 XHG=1727 XHG=1820 XHG=1946 XHG=2205 YBD=2836 YHG=2796>Henderson, YBD=2833 YBD=2827 YHG=2797>shortly ; YHG=2796>received YHG=2798>too YHG=2796>little YHG=2796>attention YHG=2796>but XBD=142 XHG=893 XBD=234 XBD=333 XBD=445 XBD=547 XBD=640 XBD=865 XBD=963 XBD=1029 XBD=1101 XBD=1162 XBD=1289 XHG=103 XHG=168 XHG=259 XHG=361 XHG=470 XHG=574 XHG=667 XHG=990YBD=2860 XHG=1059 XHG=1127 XHG=1189 YBD=2859 YBD=2861 YBD=2860 YBD=2860YHG=2839>one YBD=2869 YBD=2859 YHG=2829>in YHG=2829>the YHG=2829>last YHG=2839>case YHG=2839>was YHG=2831>the YHG=2839>enormous YHG=2830>of YHG=2831>10 YHG=2838>g. YHG=2829>four"" XBD=2536 XBD=1445 XBD=1753 XBD=1912 XBD=2013 XBD=2349 XHG=1351 XHG=1472 XHG=1779 XHG=1936 XHG=2039 XHG=2375 YBD=2872 YBD=2880 YBD=2871 YBD=2879 YHG=2841>with YHG=2840>characteristic YHG=2840>vigour YHG=2839>and YHG=2840>outspokenness, YHG=2839>pursued "" XBD=1287 XBD=250 XBD=351 XBD=589 XBD=819 XBD=941 XBD=1010 XBD=1068 XBD=1168 XHG=102 XHG=276 XHG=375 XHG=613 XHG=967 XHG=1034 XHG=1092 XHG=1193 YBD=2903 YBD=2912 YBD=2913 YBD=2904 YBD=2913 YBD=2903 YBD=2904 YHG=2873>hourly, YHG=2874>and YHG=2875>symptoms YHG=2874>developed YHG=2874>60 YHG=2882>g. YHG=2873>had YHG=2872>been XBD=1490XHG=843 XBD=1539 XBD=1763 XBD=1885 XBD=1974 XBD=2146 XBD=2246 XBD=2387 XBD=2461 XBD=2535 XHG=1352YBD=2904 XHG=1516 XHG=1563 XHG=1786 XHG=1908 XHG=1998 XHG=2169 XHG=2271 XHG=2411 XHG=2487 YBD=2915YHG=2874>after YBD=2923 YBD=2914 YBD=2916 YBD=2922 YHG=2884>almost YHG=2893>a YHG=2884>campaign YHG=2883>until YHG=2884>the YHG=2883>subject YHG=2893>was YHG=2883>taken YHG=2893>up YHG=2883>by XBD=239 XHG=878 XBD=316 XBD=405 XBD=539 XBD=637 XBD=764 XBD=854 XBD=985 XBD=1103 XBD=1288 XHG=102 XHG=278 XHG=339 XHG=430 XHG=561 XHG=663 XHG=788 XHG=1008YBD=2948 XHG=1127 YBD=2956 YBD=2946 YBD=2947 YBD=2949 YBD=2948YHG=2918>doses YBD=2951 YHG=2917>given YHG=2917>in YHG=2917>the YHG=2917>other YHG=2919>two YHG=2927>cases YHG=2918>the YHG=2926>were; YHG=2916>smaller, "" XBD=2536 XBD=1418 XBD=1592 XBD=1791 XBD=1958 XBD=2016 XBD=2136 XBD=2255 XBD=2346 XBD=2452 XHG=1351 XHG=1431 XHG=1607 XHG=1805 XHG=1971 XHG=2028 XHG=2148 XHG=2270 XHG=2358 XHG=2464 YBD=2967 YBD=2963 YBD=2957 YBD=2958 YHG=2928>the YHG=2927>Medical YHG=2927>Research YHG=2925>Council YHG=2927>20 YHG=2936>years YHG=2927>later, YHG=2927>and YHG=2927>Dale YHG=2926>and "|>"XBD=1290 XBD=248 XBD=330 XBD=445 XBD=536 XBD=631 XBD=932 XBD=987 XBD=1088 XBD=1198 XBD=881XHG=948 XHG=103 XHG=264 XHG=346 XHG=459 XHG=553 XHG=896 XHG=1003 XHG=1104 XHG=1215 XHG=645YBD=2991 YBD=2999 YBD=2990 YBD=3001 YBD=3000 YBD=2999 YBD=2991 YHG=2960>though YHG=2959>the YHG=2960>total YHG=2970>was YHG=2961>still YHG=2971>g. YHG=2961>large―87-5 YHG=2960>four YHG=2960>days YHG=2960>and XBD=1484 XBD=1635 XBD=1775 XBD=1885 XBD=2047 XBD=2220 XBD=2320 XBD=2535 XHG=1352 XHG=1507 XHG=1655 XHG=1797 XHG=1907 XHG=2070 XHG=2242 XHG=2342 YBD=3010YHG=2961>in YBD=3001 YBD=3002 YBD=3009 YHG=2971>Evans YHG=2971>(1926) YHG=2971>found YHG=2971>that YHG=2971>carbon YHG=2970>dioxide YHG=2965>was YHG=2979>necessary " XBD=1286 XBD=147 XBD=216 XBD=291 XBD=398 XBD=540 XBD=638 XBD=832 XBD=993 XBD=1177 XHG=103 XHG=181 XHG=251 XHG=323 XHG=433 XHG=593 XHG=672 XHG=864 XHG=1031 XHG=1210 YBD=3043 YBD=3033 YBD=3042 YBD=3034 YBD=3035 YBD=3045 YBD=3035 YBD=3034 YHG=3005>89 YHG=3013>g. YHG=3003>in YHG=3003>five YHG=3003>days. YHG=3004>In YHG=3005>another YHG=3014>paper, YHG=3004>Stainer XBD=1409 XHG=2492 XBD=1495 XBD=1650 XBD=1906 XBD=1963 XBD=2046 XBD=2284 XBD=2440 XBD=2535 XHG=1350 YBD=3045 XHG=1428 XHG=1513 XHG=1667 XHG=1924 XHG=1981 XHG=2065 XHG=2303 YBD=3046 YHG=3004>and YBD=3054 YHG=3015>for YHG=3015>the YHG=3024>proper YHG=3015>functioning YHG=3014>of YHG=3014>the YHG=3015>vasomotor YHG=3016>centre. YHG=3014>In " XBD=2535 XBD=301 XHG=912 XBD=514 XBD=618 XBD=877 XBD=988 XBD=1213 XBD=1291 XHG=103 XHG=338 XHG=552 XHG=657 XHG=1023YBD=3079 XHG=1250 YBD=3086 YBD=3077 YBD=3087 YBD=3078YHG=3048>and YBD=3077 YHG=3047>Stapleton YHG=3056>compare YHG=3047>the YHG=3048>absorption YHG=3048>excretion YHG=3047>of " XBD=1417 XBD=1655 XBD=1909 XBD=2016 XBD=2185 XBD=2357 XHG=1350 XHG=1449 XHG=1688 XHG=1939 XHG=2048 XHG=2216 XHG=2389 YBD=3088 YBD=3089 YHG=3058>the YHG=3059>meantime YHG=3059>Henderson YHG=3058>had YHG=3058>caused YHG=3058>carbon YHG=3058>dioxide "" XBD=1288 XBD=453 XBD=801 XBD=923 XHG=102 XHG=501 XHG=970 YBD=3130 YBD=3128 YBD=3122 YBD=3130 YHG=3091>sulphaguanidine, YHG=3090>sulphathiazole YHG=3093>and YHG=3090>succinylsulphaXBD=1392XHG=847 XBD=1455 XBD=1596 XBD=1650 XBD=1731 XBD=1931 XBD=1987 XBD=2149 XBD=2256 XBD=2328 XBD=2533 XHG=1350 XHG=1408 XHG=1470 XHG=1611 XHG=1667 XHG=1747 XHG=1947 XHG=2001 XHG=2163 XHG=2270 XHG=2342 YBD=3133 YBD=3131 YBD=3141 YBD=3132 YHG=3102>be YHG=3102>added YHG=3104>to YHG=3102>the YHG=3102>cylinders YHG=3102>of YHG=3111>oxygen YHG=3102>used YHG=3102>for YHG=3102>resuscita"" XBD=1289 XBD=263 XBD=643 XBD=720 XBD=938 XBD=1228 XHG=101 XHG=303 XHG=682 XHG=978 XHG=1267 YBD=3172 YBD=3164 YBD=3173 YBD=3164 YHG=3134>thiazole YHG=3133>(sulphasuxidine) YHG=3134>in YHG=3134>maintaining YHG=3143>a XBD=1433XHG=760 XBD=1520 XBD=1745 XBD=2086 XBD=2159 XBD=2313 XBD=2423 XBD=2533 XHG=1349YBD=3170 XHG=1467 XHG=1555 XHG=1780 XHG=2121 XHG=2194 XHG=2348 XHG=2456 YBD=3184YHG=3134>children, YBD=3185 YBD=3176 YBD=3175 YHG=3146>tion YHG=3146>by YHG=3154>surgeons, YHG=3145>rescue-workers YHG=3146>in YHG=3145>mines YHG=3146>and YHG=3145>fire"|>" XBD=264 XBD=425 XBD=487 XBD=651 XBD=741 XBD=826 XBD=1085 XBD=1146 XBD=594XHG=764 XHG=99 XHG=287 XHG=447 XHG=616 XHG=674 XHG=848 XHG=1110 XHG=1168 XHG=511 YBD=3207 YBD=3207 YBD=3214 YBD=3215 YBD=3216 YBD=3216 YBD=3207 YBD=3215 YBD=3216 YHG=3178>uniform YHG=3178>dosage YHG=3176>of YHG=3185>g. YHG=3186>per YHG=3177>kg. YHG=3177>four-hourly YHG=3177>0-05 YHG=3180>(a YHG=3177>figure " XBD=1286 XBD=1537 XBD=1649 XBD=1755 XBD=1863 XBD=2179 XBD=2276 XBD=2411 XBD=2534 XHG=1350 XHG=1592 XHG=1679 XHG=1785 XHG=1895 XHG=2210 XHG=2305 XHG=2441 YBD=3227 YBD=3228 YBD=3219 YHG=3188>brigades. YHG=3189>He YHG=3189>had YHG=3188>also YHG=3188>demonstrated YHG=3189>the YHG=3191>great YHG=3189>vari" XBD=1288 XBD=191 XHG=797 XBD=304 XBD=358 XBD=461 XBD=515 XBD=596 XBD=692 XBD=781 XBD=963 XBD=1018 XBD=1197 XHG=100 XHG=207 XHG=318 XHG=375 XHG=476 XHG=529 XHG=610 XHG=705 XHG=979YBD=3258 XHG=1043 XHG=1212 YBD=3259 YBD=3250 YBD=3249 YBD=3250 YBD=3251YHG=3220>patients YBD=3250 YHG=3230>very YHG=3220>close YHG=3221>to YHG=3220>that YHG=3220>of YHG=3219>the YHG=3218>first YHG=3220>two YHG=3221>of YHG=3220>Crofton YHG=3220>and 4. Smith, H. G. Brit. med. J. Feb. 26, 1944, p. 287. " XBD=1287 XBD=246 XHG=871 XBD=326 XBD=571 XBD=718 XBD=849 XBD=969 XBD=1142 XHG=99 XHG=268 XHG=346 XHG=592 XHG=771 XHG=989YBD=3302 XHG=1163 YBD=3302 YBD=3292 YBD=3293 YBD=3301 YBD=3293 YHG=3263>Diggle) YHG=3263>for YHG=3263>forty-eight YHG=3262>hours. YHG=3262>The YHG=3263>total YHG=3264>urinary YHG=3273>excre5. Jamieson, W. M., Brodie, J. and Stiven, D. H.,

Dewing, T., Foster, G. E., Gray, W. H., Smith, S. and Stephenson, D. Biochem. J. 1938, 32, 1101. 2. Marshall, E. K., Bratton, A. C., White, H. J. and Litchfield, J. T. Bull. Johns Hopk. Hosp. 1940, 67, 163, 3. Cole, S. L. J. Amer. med. Ass. 1912, 120, 196. 1.

Buttle, G.

A.

Ibid, March 4, 6. Whyte, J. H. S. Ibid, March 11, 1944, p. 373. 1944, p.322. 7. Paulley, J. W. Lancet, 1942, ii, 592. 8. Favourable findings in mice with succinyl sulphapyrazine and malyl sulphathiazole are reported by Callomon, F. T. and Raiziss, G. W. J. Pharmacol. 1943, 79, 200.