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(PC), external quality control (QC) schemes, and new approaches to QC in clmical microbiology. Chapter 6 includes a selection of topics involving the use of a PC (computational errors, direct capture of data from an instrument and high-resolution graphs from a dot-matrix printer). Unfortunately, the list of supplementary reading has not been updated, apart from references to articles on the floating point.
W.M. Grogan and J.M. Collins, Guide to Flow Cytometry Methods, Dekker, New York, 1990 (ISBN 0-8247-8330-l). x + 228 pp. Price US$119.50. The technique of flow cytometry has evolved from a device developed in the 1950s for counting blood cells by means of differences in electrical conducttvity between the cells and their medium. In a typical flow cytometer cells in suspension, usually stained with a fluorescent dye, are made to flow in single file through a beam of illuminating hght, usually from a laser. Fluorescent and scattered radiation can be monitored by suitably located optics and photomultiplier tubes. After passing through the light beam cells can subsequently be sorted and collected. Most of the applications to date have been m the clinical field, e.g. for DNA analysis, immunofluorescence and intracellular parameters. There is however considerable potential for its application m other areas, e.g. for monitoring phytoplankton in marine environments, and for this reason the book may be of interest to a variety of scientists.
K L. Zirm and J. Mayer (Eds.), The Management of Hazardous Substances m the Envrronment, Elsevier Applied Science, Barkmg, 1990 (ISBN l85166-459-9). xiii + 200 pp. Price aO.00. This publication contains 14 of the lectures presented at the first international congress of the
ANALYTICA
CHIMICA
ACTA
Intemattonal Society for Environmental Protection held in Vienna m February 1989. The conference had three parallel sessions covering scientific, technical and economic aspects of contemporary environmental protection problems with the emphasis apparently being on water quality. Contemporary management of water requires the identlficatton and removal of a wide range of organic mtcropollutants and of nutrients such as phosphate and nitrate which contrasts with historical requirements for the measurement of more general pollution indicators such as biological oxygen demand. This book covers specific saentific and technical matters such as pollution control technology for boilers, furnaces and incmerators, waste water treatment technologies and recycling technologies. It also has more general chapters on e.g. strategies for environmental pohcy and cooperation, the responsibilities of the mternational chermcal industry and intematronal strategies for environmental policy. It is not of particular interest to analytical chemists but contains useful background material for individuals with a responsibility for waste management and environmental protection.
Monographs on the Evaluation of Carcmogemc Risks to Humans, Vol. 49, Chromium, Nickel and Weldmg, World Health Organisation, International Agency for Research on Cancer, 1990 (ISBN 92-832-1249-5). 677 + viii pp. Price SF 95.00.
This is the largest book yet in this series, and covers, m the now well established format, mformation relevant to evaluating the carcmogenic risk of chromium and its compounds, nickel and its compounds, and those arising from all types of welding activity. It is supported by masses of data, and extensive literature references. Appendices of 119 pages detail activity profiles for genetic effects. The book concludes with a cumulative cross index to all volumes and supplements.