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THE MARINE TOXIN OKADAIC ACID REDUCES O2− GENERATION AND TYROSINE PHOSPHORYLATION IN LPS-PRIMED RAT NEUTROPHILS
e +
Abstract. in vivo
a a
~
Introduction
a 1
a
Methods
B C a
+ +
>
C
5
#
+ a a pc Results
a a a
Pc P C
A
I■ LPS-PMNOKA 4 ❑ LPS-PMNDMSO ● SAL-PMNOKA ~ 1 o SAL-PMNDMSO
I
I
9 8
B T
I
7 6 5 4
3L---0
1
2
3
05
4
10 15 20 25 30
1 a %
+ < 12345678
-112
- S
+ + SAL-PMN t + OKA[PM] 2 0 2 0 1 0 1 0 Densitometry 123 17.119 39.722.422.710.724.S 72 100 48 100 99 100 44 100 2
%
B
A 1-. 1-
TT.
<
12345
6
7
x
-55
+ SAL-PMN + Genistein [PM] 300 Densitometry 1.6 90 Control 44
+
+ 0
300
0
3.6 100
1.0 20
5.1 100
70
+
+
300 483 805
0 6.0 100
+
+
300
0
465
Discussion
a
1
a
a a a
in
1 2
a
a a
a a
a
a
Acknowledgements
a
References Y. MURAKAMI, Y. OSHIMA
A
Abstract. in vivo
a a
~
Introduction
a 1
a
Methods
B C a
+ +
>
C
5
#
+ a a pc Results
a a a
Pc P C
A
I■ LPS-PMNOKA 4 ❑ LPS-PMNDMSO ● SAL-PMNOKA ~ 1 o SAL-PMNDMSO
I
I
9 8
B T
I
7 6 5 4
3L---0
1
2
3
05
4
10 15 20 25 30
1 a %
+ < 12345678
-112
- S
+ + SAL-PMN t + OKA[PM] 2 0 2 0 1 0 1 0 Densitometry 123 17.119 39.722.422.710.724.S 72 100 48 100 99 100 44 100 2
%
B
A 1-. 1-
TT.
<
12345
6
7
x
-55
+ SAL-PMN + Genistein [PM] 300 Densitometry 1.6 90 Control 44
+
+ 0
300
0
3.6 100
1.0 20
5.1 100
70
+
+
300 483 805
0 6.0 100
+
+
300
0
465
Discussion
a
1
a
a a a
in
1 2
a
a a
a a
a
a
Acknowledgements
a
References Y. MURAKAMI, Y. OSHIMA
A